Prevalence and Distribution of ß-Thalassemia Patients in Al-Najaf province.

AL-KENANI, HEYAM QAID MOHAMMED; MEJBEL, FATIMA ABDUL-HUSSEIN

Beta-thalassemia is the most severe genetic condition arising from a reduction or lack of ß-globin chains that usually form part of the adult hemoglobin. This study was conducted with 96 male and female patients aged between 1-50 years visiting the Thalassemia Center at Al-Zahra Teaching Hospital in Al-Najaf, Iraq for disease management and 90 volunteer healthy as a control group. The sample collection took place between April 2019 and the end of August 2019. This research seems to be 44.2 % for males and 55.8 % for females for thalassemia patients, with the greater prevalence of 1-10 with 11-20 years, which was 39 (40.6 percent) relative to other categories. This research showed the highest incidence of female patients of age of 1-10 and 11-20 accompanied by 21-30 and the lowest prevalence in 41-50 who were 39%, 39%, 15% and 3% respectively, resulting in a substantial difference in the p-value of 0.05 betwwen male patients in all age groups, as well as female patients in all age groups and showing a significant difference in the p-value of 0.05. During the time of study, 19 (19.8 %) patients had splenectomy and 77 (80.2 %) patients had regular spleen in remainder. Conclusion: The highest prevalence of infection with thalassemia was in female than men, and the highest incidence of infection with thalassemia was in age group (1-10 and 11-20) years. Eventually, the greatest proportion of female patients of age was observed of 1-10 and 11-20 relative to certain categories, culminating in a substantial differential at p-value 0.05 and demonstrating a small gap between male and female patients at p-value 0.05.

NAJAF (Iraq); FETAL hemoglobin; AGE groups; WOMEN patients; DISEASE management; TEACHING hospitals; BETA-Thalassemia

International Journal of Pharmaceutical Research (09752366), 2020, p803

0975-2366

Academic Journal

10.31838/ijpr/2020.SP1.125