Helicobacter Pylori and Recent Ischemic Stroke: Is there a Relationship?

ALDHALMI, AHMED KHALID; ALDABBAGH, LAITH; HAMAD, AMMAR JABBAR; ALMUHANA, SADIQ J.; HASSOUN, HAYDER K.; ALAREEDH, MOHAMMED DHAMIN; ALMUDAFER, AHMED; JABER, JABER HATIF

Background: Stroke is an acute focal brain dysfunction due to vascular disease. Stroke is the third most basic reason for death on the planet. Helicobacter pylori is a gram-negative microaerophilic pole discovered most regularly in the more profound bits of the mucous gel covering the gastric mucosa. Several studies were done on H. pylori infection that reported organization between H. pylori and endothelial dysfunction, chronic inflammation, dyslipidemia, impaired glucose metabolism, metabolic syndrome, peripheral vascular disease and coronary conduit illness. Patients and methods: This case control study was carried out in Al-Najaf city for a period of fourteen months from January 2015 to February 2016. This study included one hundred patients presented with newly diagnosed ischemic stroke, fifty male and fifty female and one hundred control patients (50 males and 50 females) who consulted the Middle Euphrates neurological screen center for diseases rather than stroke. The ages of all persons in this study ranged from 40 to 60 years. Results: The presence of H. pylori in patients with ischemic stroke was 56%, while it was 44% in controls; however, the difference was statistically not significant (p>0.05). There is significant association between H. pylori and recent atheroembolic ischemic stroke in diabetic patients. There is no statistically significant association between H. pylori infection and severity of recent ischemic stroke. Conclusion: There is no significant relationship between H. pylori infection and ischemic stroke after stratification of other cofounder risk factors.

NAJAF (Iraq); ISCHEMIC stroke; HELICOBACTER pylori; PERIPHERAL vascular diseases; STROKE; GASTRIC mucosa

International Journal of Pharmaceutical Research (09752366), 2020, Vol 12, Issue 4, p2828

0975-2366

Academic Journal

10.31838/ijpr/2020.12.04.390