Title: Crystal Growth and Structural Refinement of Chlorzoxazone (5-Chloro-3H-benzooxazol-2-one): An Effective Muscle Relaxant.
Authors: SHARMA, RANJANA; PRASHER, DIXIT; TIWARI, R. K.
Abstract: The title compound, chlorzoxazone has a good medicinal interest in the treatment of painful musculoskeletal conditions and is also used to inhibit allergic rhinitis and asthma. In crystal structure interpretation of chlorzoxazone were carried out by operating single X The structural refinement was done by using SHELXS 97 program. It was observed that the cry chlorzoxazone undergoes in space group P = 9.0202(5) Ǻ, c = 10.0463(5) Ǻ, α = 93.435 (4)0, calculated density is 1.658 Mg m-3. The value for structure factor was 172 and final R = 0 reflections.
Subjects: CHLORZOXAZONE; CRYSTAL structure; X-ray diffraction; RHINITIS; ASTHMA
Publication: International Journal of Pharmaceutical Research (09752366), 2020, Vol 12, Issue 1, p409
ISSN: 0975-2366
Publication type: Academic Journal
DOI: 10.31838/ijpr/2020.12.01.071

Crystal Growth and Structural Refinement of Chlorzoxazone (5-Chloro-3H-benzooxazol-2-one): An Effective Muscle Relaxant.

SHARMA, RANJANA; PRASHER, DIXIT; TIWARI, R. K.