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AMPK activation: a therapeutic target for type 2 diabetes ?
- Published in:
- Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy, 2014, v. 7, p. 241, doi. 10.2147/DMSO.S43731
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- Publication type:
- Article
SIRT4 controls the balance between lipid synthesis and catabolism by repressing malonyl-CoA decarboxylase.
- Published in:
- 2012
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- Publication type:
- Abstract
Malonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytes
- Published in:
- FEBS Letters, 2005, v. 579, n. 29, p. 6581, doi. 10.1016/j.febslet.2005.10.050
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- Publication type:
- Article
Use of glucocorticoids in the palliative treatment of metastatic brain tumors.
- Published in:
- Cancer (0008543X), 1965, v. 18, n. 3, p. 298, doi. 10.1002/1097-0142(196503)18:3<298::AID-CNCR2820180306>3.0.CO;2-H
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- Publication type:
- Article
Regulation of muscle malonyl-CoA levels in the nutritionally insulin-resistant desert gerbil, Psammomys obesus.
- Published in:
- Diabetes/Metabolism Research & Reviews, 2002, v. 18, n. 3, p. 217, doi. 10.1002/dmrr.288
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- Publication type:
- Article
Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats.
- Published in:
- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0127388
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- Publication type:
- Article
Overexpression of SIRT1 in Rat Skeletal Muscle Does Not Alter Glucose Induced Insulin Resistance.
- Published in:
- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121959
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- Publication type:
- Article
Resveratrol Prevents Oxidative Stress-Induced Senescence and Proliferative Dysfunction by Activating the AMPK-FOXO3 Cascade in Cultured Primary Human Keratinocytes.
- Published in:
- PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0115341
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- Publication type:
- Article
Glucagon-Like Peptide-1 (GLP-1) Analog Liraglutide Inhibits Endothelial Cell Inflammation through a Calcium and AMPK Dependent Mechanism.
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097554
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- Publication type:
- Article
Acute Activation of AMP-Activated Protein Kinase Prevents H<sub>2</sub>O<sub>2</sub>-Induced Premature Senescence in Primary Human Keratinocytes.
- Published in:
- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035092
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- Publication type:
- Article
Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686.
- Published in:
- 2015
- By:
- Publication type:
- Letter
Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes.
- Published in:
- Diabetes, 2015, v. 64, n. 3, p. 673, doi. 10.2337/db14-0694
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- Publication type:
- Article
Pioglitazone Acutely Reduces Energy Metabolism and Insulin Secretion in Rats.
- Published in:
- Diabetes, 2013, v. 62, n. 6, p. 2122, doi. 10.2337/db12-0428
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- Publication type:
- Article
Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: association with changes in cAMP, energy state, and endogenous fuel mobilization.
- Published in:
- 2009
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- Publication type:
- journal article
Activation of AMP-Activated Protein Kinase by Interleukin-6 in Rat Skeletal Muscle.
- Published in:
- Diabetes, 2009, v. 58, n. 9, p. 1953, doi. 10.2337/db08-1293
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- Publication type:
- Article
AMPK, insulin resistance, and the metabolic syndrome.
- Published in:
- Journal of Clinical Investigation, 2013, v. 123, n. 7, p. 2764, doi. 10.1172/JCI67227
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- Publication type:
- Article
Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells.
- Published in:
- Bioscience Reports, 2016, v. 36, n. 5, p. 1, doi. 10.1042/BSR20160174
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- Publication type:
- Article
Metabolic and hormonal interactions between muscle and adipose tissue.
- Published in:
- Proceedings of the Nutrition Society, 2004, v. 63, n. 2, p. 381, doi. 10.1079/PNS2004356
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- Publication type:
- Article
Pancreatic β-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Cε, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene Expression.
- Published in:
- PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153017
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- Publication type:
- Article
Chronic Inhibition of AMP-activated Protein Kinase (AMPK) Augments Oxidative Stress, and Stimulates Basal and TNF-Alpha-Induced NF-kappaB Transactivation.
- Published in:
- Diabetes, 2007, v. 56, p. A515
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- Publication type:
- Article
Interleukin-6 Activation of AMPK Involves Both Jak-Stat and Cyclic AMP-Mediated Signaling.
- Published in:
- Diabetes, 2007, v. 56, p. A510
- By:
- Publication type:
- Article
AMP-Activated Protein Kinase Activity Is Altered by Changes in Redox State in HepG2 Cells by a SIRT1-Dependent Mechanism.
- Published in:
- Diabetes, 2007, v. 56, p. A394
- By:
- Publication type:
- Article
Lipolysis Decreases the Energy State and Activates AMP-Activated Protein Kinase (AMPK) in the Adipocyte.
- Published in:
- Diabetes, 2007, v. 56, p. A355
- By:
- Publication type:
- Article
Pharmacological Blockade of Acety1-CoA Carboxylase System Prevents Insulin Resistance and PKC θ Activation in Incubated Rat Muscle.
- Published in:
- Diabetes, 2007, v. 56, p. A333
- By:
- Publication type:
- Article
Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome.
- Published in:
- 2006
- By:
- Publication type:
- journal article
Palmitate-induced apoptosis in cultured bovine retinal pericytes: roles of NAD(P)H oxidase, oxidant stress, and ceramide.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Glucose autoregulates its uptake in skeletal muscle: involvement of AMP-activated protein kinase.
- Published in:
- 2003
- By:
- Publication type:
- journal article
Glucose Autoregulates Its Uptake in Skeletal Muscle.
- Published in:
- Diabetes, 2003, v. 52, n. 7, p. 1635, doi. 10.2337/diabetes.52.7.1635
- By:
- Publication type:
- Article
AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Fatty Acid Oxidation and the Regulation of Malonyl-CoA in Human Muscle.
- Published in:
- Diabetes, 2000, v. 49, n. 7, p. 1078, doi. 10.2337/diabetes.49.7.1078
- By:
- Publication type:
- Article
Hyperglycemia inhibits insulin activation of Akt/protein kinase B but not phosphatidylinositol 3-kinase in rat skeletal muscle.
- Published in:
- 1999
- By:
- Publication type:
- journal article
Enhanced stimulation of diacylglycerol and lipid synthesis by insulin in denervated muscle. Altered protein kinase C activity and possible link to insulin resistance.
- Published in:
- 1991
- By:
- Publication type:
- journal article
Metabolic Syndrome: Adenosine Monophosphate-activated Protein Kinase and Malonyl Coenzyme A.
- Published in:
- Obesity (19307381), 2006, v. 14, p. 25S, doi. 10.1038/oby.2006.279
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- Publication type:
- Article
Hyperglycemia and Insulin Resistance: Possible Mechanisms.
- Published in:
- Annals of the New York Academy of Sciences, 2002, v. 967, n. 1, p. 43, doi. 10.1111/j.1749-6632.2002.tb04262.x
- By:
- Publication type:
- Article
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
- Published in:
- Nature, 2010, v. 464, n. 7285, p. 121, doi. 10.1038/nature08778
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- Publication type:
- Article
An Electron Microscopic Study of Lipoprotein Production and Release by the Isolated Perfused Rat Liver.∗.
- Published in:
- Proceedings of the Society for Experimental Biology & Medicine, 1966, v. 123, n. 1, p. 4, doi. 10.3181/00379727-123-31388
- By:
- Publication type:
- Article
Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals.
- Published in:
- 2014
- By:
- Publication type:
- journal article
Partial Characterization of an Insulin-dependent Serum Factor that Regulates Ornithine Decarboxylase in Skeletal Muscle.
- Published in:
- Diabetes, 1982, v. 31, n. 6, p. 500, doi. 10.2337/diab.31.6.500
- By:
- Publication type:
- Article
Regulation of Ornithine Decarboxylase in Skeletal Muscle.
- Published in:
- Diabetes, 1981, v. 30, n. 8, p. 678, doi. 10.2337/diab.30.8.678
- By:
- Publication type:
- Article
The effect of physical training on glucose tolerance and plasma lipids in maturity-onset diabetes.
- Published in:
- 1979
- By:
- Publication type:
- journal article
Substrate utilization in perfused skeletal muscle.
- Published in:
- 1979
- By:
- Publication type:
- journal article
Glucose and amino acid metabolism in perfused skeletal muscle. Effect of dichloroacetate.
- Published in:
- 1978
- By:
- Publication type:
- journal article
Glucose metabolism in rat skeletal muscle at rest. Effect of starvation, diabetes, ketone bodies and free fatty acids.
- Published in:
- 1974
- By:
- Publication type:
- journal article
Effect of acute insulin deprivation on rat liver glucokinase.
- Published in:
- 1968
- By:
- Publication type:
- journal article
Insulin Resistance in Type 2 Diabetes: Association with Truncal Obesity, Impaired Fitness, and Atypical Malonyl Coenzyme A Regulation.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 1, p. 82, doi. 10.1210/jc.2002-020330
- By:
- Publication type:
- Article
Why Might Thiazolidinediones Increase Exercise Capacity in Patients With Type 2 Diabetes?
- Published in:
- 2005
- By:
- Publication type:
- Editorial
Cutting the Gordian Knot.
- Published in:
- Diabetes Care, 1999, v. 22, n. 11, p. 1912, doi. 10.2337/diacare.22.11.1912
- By:
- Publication type:
- Article
Ten-year experience with an exercise-based outpatient life-style modification program in the treatment of diabetes mellitus.
- Published in:
- 1992
- By:
- Publication type:
- journal article
Diabetes, exercise, and atherosclerosis.
- Published in:
- 1992
- By:
- Publication type:
- journal article