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- Title
INNOVATIVE CHARACTERIZATION OF CURCUMIN NANOPARTICLES AS ADVANCED PHYTOPHARMACEUTICALS.
- Authors
Sodik, J. J.; Dinata, D. I.; Jafar, G.; Fakih, T. M.; Putranto, M. F.; Syarifuddin, F.; Wijayanti, S.
- Abstract
Curcumin provides numerous advantages, including its antioxidant, antibacterial, anticancer, and anti-inflammatory properties. Despite these advantages, its ability to be absorbed by the body is limited. One effective method to improve curcumin's absorption is by developing curcumin nanoparticles. These nano-sized particles have several advantages over larger particles, notably a larger surface area that enhances absorption and improves penetration into cells. The nanoparticles produced will undergo analysis to determine their formulation characteristics by using particle size analysis (PSA) instruments to evaluate parameters such as particle dimensions, polydispersity index (PDI), and zeta potential. Morphology will also be examined using Fourier Transform Infrared Spectroscopy (FTIR) and Transmission Electron Microscopy (TEM). TEM results indicate that curcumin nanoparticles are smaller than 100 nm. FTIR analysis of nano-curcumin reveals the presence of functional groups typical of curcumin (C=O and O-H).
- Subjects
FOURIER transform infrared spectroscopy; TRANSMISSION electron microscopes; TRANSMISSION electron microscopy; PARTICLE analysis; CURCUMIN; ZETA potential
- Publication
Rasayan Journal of Chemistry, 2024, Vol 17, Issue 4, p1860
- ISSN
0974-1496
- Publication type
Academic Journal
- DOI
10.31788/RJC.2024.1749019