Results
Title

INNOVATIVE CHARACTERIZATION OF CURCUMIN NANOPARTICLES AS ADVANCED PHYTOPHARMACEUTICALS.

Authors

Sodik, J. J.; Dinata, D. I.; Jafar, G.; Fakih, T. M.; Putranto, M. F.; Syarifuddin, F.; Wijayanti, S.

Abstract

Curcumin provides numerous advantages, including its antioxidant, antibacterial, anticancer, and anti-inflammatory properties. Despite these advantages, its ability to be absorbed by the body is limited. One effective method to improve curcumin's absorption is by developing curcumin nanoparticles. These nano-sized particles have several advantages over larger particles, notably a larger surface area that enhances absorption and improves penetration into cells. The nanoparticles produced will undergo analysis to determine their formulation characteristics by using particle size analysis (PSA) instruments to evaluate parameters such as particle dimensions, polydispersity index (PDI), and zeta potential. Morphology will also be examined using Fourier Transform Infrared Spectroscopy (FTIR) and Transmission Electron Microscopy (TEM). TEM results indicate that curcumin nanoparticles are smaller than 100 nm. FTIR analysis of nano-curcumin reveals the presence of functional groups typical of curcumin (C=O and O-H).

Subjects

FOURIER transform infrared spectroscopy; TRANSMISSION electron microscopes; TRANSMISSION electron microscopy; PARTICLE analysis; CURCUMIN; ZETA potential

Publication

Rasayan Journal of Chemistry, 2024, Vol 17, Issue 4, p1860

ISSN

0974-1496

Publication type

Academic Journal

DOI

10.31788/RJC.2024.1749019