Acute promyelocytic leukaemia (APML) is the most malignant form of acute leukaemia, relatively uncommon in children, rapidly fatal if untreated and several developments have paved the way to make this disease curable. We report a first case to our knowledge in Nepal in a 12 years old boy who was diagnosed as APML and treated with all trans retinoic acid (ATRA) 14 years back and has been free from disease till date.