Works matching DE "DRUG lipophilicity"

Results: 688

Bigels: A unique class of materials for drug delivery applications.

Published in:

Soft Materials, 2018, v. 16, n. 2, p. 77, doi. 10.1080/1539445X.2018.1424638

By:

Shakeel, Ahmad;
Lupi, Francesca R.;
Gabriele, Domenico;
Baldino, Noemi;
De Cindio, Bruno

Publication type:

Article

Organogels as Matrices for Controlled Drug Delivery: A Review on the Current State.

Published in:

Soft Materials, 2014, v. 12, n. 1, p. 47, doi. 10.1080/1539445X.2012.756016

By:

Sagiri, S.S.;
Behera, B.;
Rafanan, R.R.;
Bhattacharya, C.;
Pal, K.;
Banerjee, I.;
Rousseau, D.

Publication type:

Article

Impedance technology reveals correlations between cytotoxicity and lipophilicity of mono and bimetallic phosphine complexes.

Published in:

BioMetals, 2015, v. 28, n. 4, p. 653, doi. 10.1007/s10534-015-9851-y

By:

Fonteh, P.;
Elkhadir, A.;
Omondi, B.;
Guzei, I.;
Darkwa, J.;
Meyer, D.

Publication type:

Article

Designing for topical delivery: Prodrugs can make the difference.

Published in:

Medicinal Research Reviews, 2003, v. 23, n. 6, p. 763, doi. 10.1002/med.10048

By:

Kenneth B. Sloan;
Scott Wasdo

Publication type:

Article

Recent Advances in Improving the Bioavailability of Hydrophobic/Lipophilic Drugs and Their Delivery via Self-Emulsifying Formulations.

Published in:

Colloids & Interfaces, 2023, v. 7, n. 1, p. 16, doi. 10.3390/colloids7010016

By:

Ameta, Rakesh Kumar;
Soni, Kunjal;
Bhattarai, Ajaya

Publication type:

Article

Partition of DDT and DDE into Membranes and Extracted Lipids of Bacillus stearothermophilus.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1997, v. 59, n. 5, p. 696, doi. 10.1007/s001289900536

By:

Donato, M. M.;
Antunes-Madeira, M. C.;
Jurado, A. S.;
Madeira, V. M. C.

Publication type:

Article

In vivo and in vitro dermal penetration of lipophilic and hydrophilic pesticides in mice.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1987, v. 38, n. 6, p. 917, doi. 10.1007/BF01609073

By:

Grissom, R.;
Brownie, C.;
Guthrie, F.

Publication type:

Article

Augmented simvastatin cytotoxicity using optimized lipid nanocapsules: a potential for breast cancer treatment.

Published in:

Journal of Liposome Research, 2017, v. 27, n. 1, p. 1, doi. 10.3109/08982104.2015.1137313

By:

Safwat, Sally;
Hathout, Rania M.;
Ishak, Rania A.;
Mortada, Nahed D.

Publication type:

Article

Optimization of drug loading to improve physical stability of paclitaxel-loaded long-circulating liposomes.

Published in:

Journal of Liposome Research, 2015, v. 25, n. 4, p. 308, doi. 10.3109/08982104.2014.995671

By:

Kannan, Vinayagam;
Balabathula, Pavan;
Divi, Murali K.;
Thoma, Laura A.;
Wood, George C.

Publication type:

Article

A study on the encapsulation of an occludin lipophilic derivative in liposomal carriers.

Published in:

Journal of Liposome Research, 2015, v. 25, n. 4, p. 287, doi. 10.3109/08982104.2014.992025

By:

Cupri, Sarha;
Graziano, Adriana C. E.;
Cardile, Venera;
Skwarczynski, Mariusz;
Toth, Istvan;
Pignatello, Rosario

Publication type:

Article

Effects of liposomal encapsulation on the antioxidant activity of lipophilic prodrugs of idebenone.

Published in:

Journal of Liposome Research, 2011, v. 21, n. 1, p. 46, doi. 10.3109/08982101003735996

By:

Pignatello, Rosario;
Acquaviva, Rosaria;
Campisi, Agata;
Raciti, Giuseppina;
Musumeci, Teresa;
Puglisi, Giovanni

Publication type:

Article

Effect of preparation technique on the properties and in vivo efficacy of benzocaine-loaded ethosomes.

Published in:

Journal of Liposome Research, 2009, v. 19, n. 4, p. 253, doi. 10.3109/08982100902788408

By:

Maestrelli, Francesca;
Capasso, Gaetano;
González-Rodríguez, Maria L.;
Rabasco, Antonio M.;
Ghelardini, Carla;
Mura, Paola

Publication type:

Article

Phosphatidyl choline-based colloidal systems for dermal and transdermal drug delivery.

Published in:

Journal of Liposome Research, 2009, v. 19, n. 4, p. 267, doi. 10.3109/08982100902814006

By:

Ferderber, Kristina;
Hook, Sarah;
Rades, Thomas

Publication type:

Article

Lipophilic Drug Transfer Between Liposomal and Biological Membranes: What Does It Mean for Parenteral and Oral Drug Delivery?

Published in:

Journal of Liposome Research, 2006, v. 16, n. 3, p. 281, doi. 10.1080/08982100600848702

By:

Fahr, Alfred;
van Hoogevest, Peter;
Kuntsche, Judith;
Leigh, Mathew L. S.

Publication type:

Article

Baseline Lipophilicity Relationships in Human Cytochromes P450 Associated with Drug Metabolism.

Published in:

Drug Metabolism Reviews, 2003, v. 35, n. 1, p. 1, doi. 10.1081/DMR-120018245

By:

Lewis, David F. V.;
Dickins, Maruice

Publication type:

Article

220. ATYPICAL ENZYME KINETICS OBSERVED WITH CYTOCHROME P450 2C9.

Published in:: 2002
Publication type:: Abstract

Comparison of Pharmacokinetics and Tissue Distribution Kinetics of Roxithromycin and Expression of CYP 3A1 between Pregnant Mice and Foetuses.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2017, v. 120, n. 2, p. 146, doi. 10.1111/bcpt.12668

By:

Qin, Yi;
Xu, Weizhe;
Mo, Lanjian;
Li, Xiaorong;
Ge, Beikang;
Xiong, Jie;
Gao, Lifang;
Xu, Pinxiang;
Xue, Ming

Publication type:

Article

Lipid Rescue - Efficacy and Safety Still Unproven.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2016, v. 119, n. 4, p. 345, doi. 10.1111/bcpt.12607

By:

Höjer, Jonas;
Jacobsen, Dag;
Neuvonen, Pertti J.;
Rosenberg, Per H.

Publication type:

Article

Third-Generation Beta-Adrenoceptor Antagonists in the Treatment of Hypertension and Heart Failure.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2015, v. 117, n. 1, p. 5, doi. 10.1111/bcpt.12396

By:

Fisker, Filip Y.;
Grimm, Daniela;
Wehland, Markus

Publication type:

Article

Magnetic Nanoemulsions: Comparison between Nanoemulsions Formed by Ultrasonication and by Spontaneous Emulsification.

Published in:

Nanomaterials (2079-4991), 2017, v. 7, n. 7, p. 190, doi. 10.3390/nano7070190

By:

Rodríguez-Burneo, Nathalia;
Busquets, Maria Antònia;
Estelrich, Joan

Publication type:

Article

Reversed-phase thin-layer chromatography behavior of aldopentose derivatives.

Published in:

Chemical Industry / Hemijska Industrija, 2012, v. 66, n. 3, p. 365, doi. 10.2298/HEMIND111012099L

By:

Livaja-Popović, Dragana J.;
Lončar, Eva S.;
Jevrić, Lidija R.;
MalbaŠa, Radomir V.

Publication type:

Article

Eosinophilic pustular folliculitis: successful treatment with topical pimecrolimus.

Published in:

2007

By:

Rho, N.-K.;
Kim, B.-J.

Publication type:

Letter

Formulations of Fentanyl for the Management of Pain.

Published in:

Drugs, 2010, v. 70, n. 1, p. 57, doi. 10.2165/11531740-000000000-00000

By:

Grape, Sina;
Schug, Stephan A.;
Lauer, Stefan;
Schug, Barbara S.

Publication type:

Article

Interaction of resveratrol analogues with biomembrane models: a calorimetric study on structural variations effects.

Published in:

Journal of Excipients & Food Chemicals, 2012, v. 3, n. 3, p. 96

By:

Sarpietro, Maria Grazia;
Spatafora, Carmela;
Ottimo, Sara;
Tringali, Corrado;
Castelli, Francesco

Publication type:

Article

Selecting surfactants for the maximum inhibition of the activity of the multidrug resistance efflux pump transporter, P-glycoprotein: conceptual development.

Published in:

Journal of Excipients & Food Chemicals, 2010, v. 1, n. 3, p. 51

By:

Prakash, Apte Shireesh

Publication type:

Article

Manufacturing techniques and excipients used during the formulation of oil-in-water type nanosized emulsions for medical applications.

Published in:

Journal of Excipients & Food Chemicals, 2010, v. 1, n. 1, p. 11

By:

Tamilvanan, Shunmugaperumal;
Senthilkumar, Sudalaimuthu Ramachandran;
baskar, Raj;
Sekharan, Thenrajan Raja

Publication type:

Article

A confidence predictor for logD using conformal regression and a support-vector machine.

Published in:

Journal of Cheminformatics, 2018, v. 10, n. 1, p. 1, doi. 10.1186/s13321-018-0271-1

By:

Lapins, Maris;
Arvidsson, Staffan;
Lampa, Samuel;
Berg, Arvid;
Schaal, Wesley;
Alvarsson, Jonathan;
Spjuth, Ola

Publication type:

Article

CORRELATING STUDY ON PHISYCO-CHEMICAL AND BIOLOGICAL PROPERTIES OF THIOSEMICARBAZONE AND THIADIAZOLINE DERIVATIVES.

Published in:

Studia Universitatis Babes-Bolyai, Chemia, 2012, v. 57, n. 3, p. 109

By:

IONUŢ, IOANA A.;
TIPERCIUC, BRÎNDUŞA;
ONIGA, OVIDIU;
SZEFLER, BEATA;
MATIES, RALUCA

Publication type:

Article

STUDY OF THE CHROMATOGRAPHIC RETENTION OF SOME NEW ORGANOSELENIUM AND ORGANOTELLURIUM COMPOUNDS CONTAINING INTRAMOLECULAR INTERACTIONS BY HPTLC.

Published in:

Studia Universitatis Babes-Bolyai, Chemia, 2009, n. 3, p. 71

By:

Dunca, Silvia Lenuţa;
Kulcsar, Monica;
Silvestru, Anca;
Silvestru, Cristian;
Sârbu, Costel

Publication type:

Article

Accelerated Stability Testing of a Clobetasol Propionate-Loaded Nanoemulsion as per ICH Guidelines.

Published in:

Scientia Pharmaceutica, 2013, v. 81, n. 4, p. 1089, doi. 10.3797/scipharm.1210-02

By:

ALI, Mohammad Sajid;
ALAM, Mohammad Sarfaraz;
ALAM, Nawazish;
ANWER, Tarique;
SAFHI, Mohammed Mohsen A.

Publication type:

Article

Functions of Lipids for Enhancement of Oral Bioavailability of Poorly Water-Soluble Drugs.

Published in:

Scientia Pharmaceutica, 2011, v. 79, n. 4, p. 705, doi. 10.3797/scipharm.1105-09

By:

Nanjwade, Basavaraj K.;
Patel, Didhija J.;
Udhani, Ritesh A.;
Manvi, Fakirappa V.

Publication type:

Article

Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197422

By:

Beckwitt, Colin H.;
Shiraha, Keisuke;
Wells, Alan

Publication type:

Article

Single-Photon-Emission Computed Tomography (SPECT) with Technetium Sestamibi in the Diagnosis of Small Breast Cancer and Axillary Node Involvement.

Published in:

World Journal of Surgery, 2011, v. 35, n. 12, p. 2673, doi. 10.1007/s00268-011-1271-8

By:

Jacobsson, Hans

Publication type:

Article

Effects of Hydrophilic and Lipophilic β-Blockers on Heart Rate Variability and Baroreflex Sensitivity in Normal Subjects.

Published in:

Pacing & Clinical Electrophysiology, 1998, v. 21, n. 3, p. 559, doi. 10.1111/j.1540-8159.1998.tb00099.x

By:

Pitzalis, Maria Vittoria;
Mastropasqua, Filippo;
Massari, Francesco;
Forleo, Cinzia;
Passantino, Andrea;
Colombo, Roberto;
Totaro, Paolo;
Rizzon, Paolo

Publication type:

Article

MELATONIN AND MONOAMINERGIC SYSTEM - BEHAVIOURAL ASPECTS.

Published in:

Romanian Journal of Neurology, 2016, v. 15, n. 1, p. 17, doi. 10.37897/rjn.2016.1.1

By:

Voiculescu, S. E.;
Rosca, A.;
Zahiu, C. M. D.;
Badiu, C.;
Zagrean, A. M.

Publication type:

Article

Peptide reagent design based on physical and chemical properties of amino acid residues.

Published in:

Journal of Computational Chemistry, 2007, v. 28, n. 12, p. 2043, doi. 10.1002/jcc.20732

By:

Du, Qi-Shi;
Huang, Ri-Bo;
Wei, Yu-Tuo;
Wang, Cheng-Hua;
Chou, Kuo-Chen

Publication type:

Article

Heuristic molecular lipophilicity potential (HMLP): Lipophilicity and hydrophilicity of amino acid side chains.

Published in:

Journal of Computational Chemistry, 2006, v. 27, n. 6, p. 685, doi. 10.1002/jcc.20369

By:

Qi-Shi Du;
Da-Peng Li;
Wen-Zhang He;
Kuo-Chen Chou

Publication type:

Article

Ocular Permeability Screening of Dexamethasone Esters Through Combined Cellular and Tissue Systems.

Published in:

Journal of Ocular Pharmacology & Therapeutics, 2004, v. 20, n. 1, p. 75, doi. 10.1089/108076804772745482

By:

Civiale, Claudine;
Bucaria, Filippo;
Piazza, Silvana;
Peri, Ornella;
Miano, Fausto;
Enea, Vincenzo

Publication type:

Article

Corneal Permeation of Ganciclovir:Mechanism of Ganciclovir Permeation Enhancement by Acyl Ester Prodrug Design.

Published in:

Journal of Ocular Pharmacology & Therapeutics, 2002, v. 18, n. 6, p. 535, doi. 10.1089/108076802321021081

By:

Tirucherai, Giridhar S.;
Dias, Clapton;
Mitra, Ashim K.

Publication type:

Article

Cerebrospinal fluid/plasma quotients of essential and non-essential metals in patients with Alzheimer's disease.

Published in:

Journal of Neural Transmission, 2011, v. 118, n. 6, p. 957, doi. 10.1007/s00702-011-0605-x

By:

Gerhardsson, Lars;
Lundh, Thomas;
Londos, Elisabet;
Minthon, Lennart

Publication type:

Article

A Practical Synthesis of 3,3-Difluorocyclobutane Carboxylic Acid.

Published in:

Synthetic Communications, 2005, v. 35, n. 5, p. 657, doi. 10.1081/SCC-200050350

By:

Elend, Dirk;
Fengas, David;
Fray, M.Jonathan

Publication type:

Article

Determination of the Lipophilicity of Some New Derivatives of Thiosemicarbazide and 1,2,4-triazoline-5-thione with Potential Antituberculosis Activity.

Published in:: Croatica Chemica Acta, 2010, v. 83, n. 3, p. 299
Publication type:: Article

A comparison of patient-controlled analgesia administered by the intravenous or intranasal route during the early postoperative period.

Published in:

Anaesthesia, 2002, v. 57, n. 1, p. 48, doi. 10.1046/j.1365-2044.2002.02263.x

By:

Ward, M.;
Minto, G.;
Alexander-Williams, J. M.

Publication type:

Article

Cytotoxicity evaluation of symmetrically branched glycerol trimer in human hepatocellular carcinoma HepG2 cells.

Published in:

Journal of Toxicological Sciences, 2012, v. 37, n. 5, p. 1059, doi. 10.2131/jts.37.1059

By:

Licht Miyamoto;
Masashi Watanabe;
Mai Kono;
Tsuyoshi Matsushita;
Hatsuhiko Hattori;
Keisuke Ishizawa;
Hisao Nemoto;
Koichiro Tsuchiya

Publication type:

Article

The Mechanisms of Inhibition of Frog Endplate Currents With Homologous Derivatives of the 1,1-dimethyl-3-oxybutyl Phosphonic Acid.

Published in:

Physiological Research, 2012, v. 61, n. 4, p. 395, doi. 10.33549/physiolres.932314

By:

Pryazhnikov, E.;
Ostroumov, A.;
Druginina, O.;
Vyskočil, F.;
Skorinkin, A.

Publication type:

Article

Distinct Effects of Acute Pretreatment With Lipophilic and Hydrophilic Statins on Myocardial Stunning, Arrhythmias and Lethal Injury in the Rat Heart Subjected to Ischemia/Reperfusion.

Published in:

Physiological Research, 2011, v. 60, n. 5, p. 825

By:

ČARNICKÁ, S.;
ADAMEOVÁ, A.;
NEMČEKOVÁ, M.;
MATEJÍKOVÁ, J.;
PANCZA, D.;
RAVINGEROVÁ, T.

Publication type:

Article

Effects of statin use on volumetric mammographic density: results from the KARMA study.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1457-9

By:

Skarping, Ida;
Brand, Judith S.;
Hall, Per;
Borgquist, Signe

Publication type:

Article

Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay.

Published in:

BMC Cancer, 2009, v. 9, p. 1, doi. 10.1186/1471-2407-9-38

By:

Knight, Louise A.;
Kurbacher, Christian M.;
Glaysher, Sharon;
Fernando, Augusta;
Reichelt, Ralf;
Dexel, Susanne;
Reinhold, Uwe;
Cree, Ian A.

Publication type:

Article

Interpretation of absorption rate data for inhaled fluticasone propionate obtained in compartmental pharmacokinetic modeling.

Published in:

International Journal of Clinical Pharmacology & Therapeutics, 2005, v. 43, n. 3, p. 117, doi. 10.5414/CPP43117

By:

S. Krishnaswami;
Hochhaus, G.;
Möllmann, H.;
Barth, J.;
Derendorf, H.

Publication type:

Article

Agent treats patients with BCG-refractory CIS of bladder.

Published in:

Urology Times, 1998, v. 26, n. 11, p. 38

By:

Tennant, Scott

Publication type:

Article