Works matching AU Gillies, Robert J

Results: 131

The role of carbonic anhydrase IX in cancer development: links to hypoxia, acidosis, and beyond.

Published in:

Cancer & Metastasis Reviews, 2019, v. 38, n. 1/2, p. 65, doi. 10.1007/s10555-019-09799-0

By:

Pastorekova, Silvia;
Gillies, Robert J

Publication type:

Article

Preface.

Published in:

2019

By:

Gillies, Robert J.

Publication type:

Editorial

Causes, consequences, and therapy of tumors acidosis.

Published in:

Cancer & Metastasis Reviews, 2019, v. 38, n. 1/2, p. 205, doi. 10.1007/s10555-019-09792-7

By:

Pillai, Smitha R.;
Damaghi, Mehdi;
Marunaka, Yoshinori;
Spugnini, Enrico Pierluigi;
Fais, Stefano;
Gillies, Robert J.

Publication type:

Article

Distinct regulation of pHin and [Ca2+]in in human melanoma cells with different metastatic potential.

Published in:

Journal of Cellular Physiology, 1998, v. 176, n. 1, p. 196, doi. 10.1002/(SICI)1097-4652(199807)176:1<196::AID-JCP21>3.0.CO;2-4

By:

Martínez-Zaguilán, Raul;
Martinez, Gloria M.;
Gomez, Araceli;
Hendrix, Mary J. C.;
Gillies, Robert J.

Publication type:

Article

Effect of glucose on pHin and [Ca2+]in in NIH-3T3 cells transfected with the yeast P-Type H+-ATPase.

Published in:

Journal of Cellular Physiology, 1994, v. 161, n. 1, p. 129, doi. 10.1002/jcp.1041610116

By:

Martínez, Gloria M.;
Martínez-Zaguilán, Raul;
Gillies, Robert J.

Publication type:

Article

NIH 3T3 cells transfected with a yeast H+-ATPase have altered sensitivity to insulin, insulin growth factor-I, and platelet-derived growth factor-AA.

Published in:

Journal of Cellular Physiology, 1994, v. 159, n. 3, p. 551, doi. 10.1002/jcp.1041590319

By:

Peterson, Eric P.;
Martinez, Gloria M.;
Martinez-Zaguilan, Raul;
Perona, Rosario;
Gillies, Robert J.

Publication type:

Article

Dimethylsulfoxide modifies the sensitivity of BALB/c-3T3 cells to the activation of Na+/H+ exchange by phorbol esters.

Published in:

Journal of Cellular Physiology, 1989, v. 139, n. 1, p. 131, doi. 10.1002/jcp.1041390119

By:

Martinez, Raul;
Gillies, Robert J.

Publication type:

Article

Sphingosine inhibits phorbol 12-myristate 13-acetate-, but not serum-induced, activation of Na+/H+ exchange in mammalian cells.

Published in:

Journal of Cellular Physiology, 1989, v. 139, n. 1, p. 125, doi. 10.1002/jcp.1041390118

By:

Gillies, Robert J.;
Martinez, Raul;
Sneider, Judith M.;
Hoyer, Patricia B.

Publication type:

Article

Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer.

Published in:

Science Translational Medicine, 2016, v. 8, n. 327, p. 1, doi. 10.1126/scitranslmed.aad7842

By:

Enriquez-Navas, Pedro M.;
Yoonseok Kam;
Das, Tuhin;
Hassan, Sabrina;
Silva, Ariosto;
Foroutan, Parastou;
Ruiz, Epifanio;
Martinez, Gary;
Minton, Susan;
Gillies, Robert J.;
Gatenby, Robert A.

Publication type:

Article

Evolutionary Analysis of TCGA Data Using Over- and Under- Mutated Genes Identify Key Molecular Pathways and Cellular Functions in Lung Cancer Subtypes.

Published in:

Cancers, 2023, v. 15, n. 1, p. 18, doi. 10.3390/cancers15010018

By:

Freischel, Audrey R.;
Teer, Jamie K.;
Luddy, Kimberly;
Cunningham, Jessica;
Artzy-Randrup, Yael;
Epstein, Tamir;
Tsai, Kenneth Y.;
Berglund, Anders;
Cleveland, John L.;
Gillies, Robert J.;
Brown, Joel S.;
Gatenby, Robert A.

Publication type:

Article

Modeling Tumor: Lymphatic Interactions in Lymphatic Metastasis of Triple Negative Breast Cancer.

Published in:

Cancers, 2021, v. 13, n. 23, p. 6044, doi. 10.3390/cancers13236044

By:

Ji, Kyungmin;
Zhao, Zhiguo;
Sameni, Mansoureh;
Moin, Kamiar;
Xu, Yong;
Gillies, Robert J.;
Sloane, Bonnie F.;
Mattingly, Raymond R.

Publication type:

Article

Targeting of Evolutionarily Acquired Cancer Cell Phenotype by Exploiting pHi-Metabolic Vulnerabilities.

Published in:

Cancers, 2021, v. 13, n. 1, p. 64, doi. 10.3390/cancers13010064

By:

Ordway, Bryce;
Tomaszewski, Michal;
Byrne, Samantha;
Abrahams, Dominique;
Swietach, Pawel;
Gillies, Robert J.;
Damaghi, Mehdi

Publication type:

Article

Multi-window CT based Radiomic signatures in differentiating indolent versus aggressive lung cancers in the National Lung Screening Trial: a retrospective study.

Published in:

2019

By:

Lu, Hong;
Mu, Wei;
Balagurunathan, Yoganand;
Qi, Jin;
Abdalah, Mahmoud A.;
Garcia, Alberto L.;
Ye, Zhaoxiang;
Gillies, Robert J.;
Schabath, Matthew B.

Publication type:

journal article

Radiomics predicts risk of cachexia in advanced NSCLC patients treated with immune checkpoint inhibitors.

Published in:

2021

By:

Mu, Wei;
Katsoulakis, Evangelia;
Whelan, Christopher J.;
Gage, Kenneth L.;
Schabath, Matthew B.;
Gillies, Robert J.

Publication type:

journal article

Artificial selection for host resistance to tumour growth and subsequent cancer cell adaptations: an evolutionary arms race.

Published in:

2021

By:

Ibrahim-Hashim, Arig;
Luddy, Kimberly;
Abrahams, Dominique;
Enriquez-Navas, Pedro;
Damgaci, Sultan;
Yao, Jiqiang;
Chen, Tingan;
Bui, Marilyn M.;
Gillies, Robert J.;
O'Farrelly, Cliona;
Richards, Christina L.;
Brown, Joel S.;
Gatenby, Robert A.

Publication type:

journal article

Tumor pH and Its Measurement.

Published in:

Journal of Nuclear Medicine, 2010, v. 51, n. 8, p. 1167, doi. 10.2967/jnumed.109.068981

By:

Xiaomeng Zhang;
Yuxiang Lin;
Gillies, Robert J.

Publication type:

Article

Causes and Consequences of Increased Glucose Metabolism of Cancers.

Published in:

Journal of Nuclear Medicine, 2008, v. 49, n. 6, p. 24S, doi. 10.2967/jnumed.107.047258

By:

Gillies, Robert J.;
Robey, Ian;
Gatenby, Robert A.

Publication type:

Article

Cancer heterogeneity and metastasis: life at the edge.

Published in:

Clinical & Experimental Metastasis, 2022, v. 39, n. 1, p. 15, doi. 10.1007/s10585-021-10101-2

By:

Gillies, Robert J.

Publication type:

Article

Heterogeneity analysis of MRI T2 maps for measurement of early tumor response to radiotherapy.

Published in:

NMR in Biomedicine, 2021, v. 34, n. 3, p. 1, doi. 10.1002/nbm.4454

By:

Tomaszewski, Michal R.;
Dominguez‐Viqueira, William;
Ortiz, Antonio;
Shi, Yu;
Costello, James R.;
Enderling, Heiko;
Rosenberg, Stephen A.;
Gillies, Robert J.

Publication type:

Article

Direct and indirect assessment of cancer metabolism explored by MRI.

Published in:

NMR in Biomedicine, 2019, v. 32, n. 10, p. N.PAG, doi. 10.1002/nbm.3966

By:

Kishimoto, Shun;
Oshima, Nobu;
Krishna, Murali C.;
Gillies, Robert J.

Publication type:

Article

Glioblastoma targeting via integrins is concentration dependent.

Published in:

Biotechnology & Bioengineering, 2009, v. 104, n. 2, p. 408, doi. 10.1002/bit.22424

By:

Rosca, Elena V.;
Gillies, Robert J.;
Caplan, Michael R.

Publication type:

Article

Sweat but no gain: Inhibiting proliferation of multidrug resistant cancer cells with 'ersatzdroges'.

Published in:

International Journal of Cancer, 2015, v. 136, n. 4, p. E188, doi. 10.1002/ijc.29158

By:

Kam, Yoonseok;
Das, Tuhin;
Tian, Haibin;
Foroutan, Parastou;
Ruiz, Epifanio;
Martinez, Gary;
Minton, Susan;
Gillies, Robert J.;
Gatenby, Robert A.

Publication type:

Article

Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane.

Published in:

Nature Communications, 2015, v. 6, n. 12, p. 8752, doi. 10.1038/ncomms9752

By:

Damaghi, Mehdi;
Tafreshi, Narges K.;
Lloyd, Mark C.;
Sprung, Robert;
Estrella, Veronica;
Wojtkowiak, Jonathan W.;
Morse, David L.;
Koomen, John M.;
Bui, Marilyn M.;
Gatenby, Robert A;
Gillies, Robert J

Publication type:

Article

Corrigendum: Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach.

Published in:

Nature Communications, 2014, v. 5, n. 8, p. 4644, doi. 10.1038/ncomms5644

By:

Aerts, Hugo J.W.L.;
Velazquez, Emmanuel Rios;
Leijenaar, Ralph T.H.;
Parmar, Chintan;
Grossmann, Patrick;
Carvalho, Sara;
Bussink, Johan;
Monshouwer, René;
Haibe-Kains, Benjamin;
Rietveld, Derek;
Hoebers, Frank;
Rietbergen, Michelle M.;
Leemans, C. René;
Dekker, Andre;
Quackenbush, John;
Gillies, Robert J.;
Lambin, Philippe

Publication type:

Article

Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach.

Published in:

Nature Communications, 2014, v. 5, n. 6, p. 4006, doi. 10.1038/ncomms5006

By:

Aerts, Hugo J. W. L.;
Velazquez, Emmanuel Rios;
Leijenaar, Ralph T. H.;
Parmar, Chintan;
Grossmann, Patrick;
Cavalho, Sara;
Bussink, Johan;
Monshouwer, René;
Haibe-Kains, Benjamin;
Rietveld, Derek;
Hoebers, Frank;
Rietbergen, Michelle M.;
Leemans, C. René;
Dekker, Andre;
Quackenbush, John;
Gillies, Robert J.;
Lambin, Philippe

Publication type:

Article

pH sensing and regulation in cancer.

Published in:

Frontiers in Physiology, 2013, v. 4, p. 1, doi. 10.3389/fphys.2013.00370

By:

Damaghi, Mehdi;
Wojtkowiak, Jonathan W.;
Gillies, Robert J.

Publication type:

Article

Differences in Patient Outcomes of Prevalence, Interval, and Screen-Detected Lung Cancers in the CT Arm of the National Lung Screening Trial.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0159880

By:

Schabath, Matthew B.;
Massion, Pierre P.;
Thompson, Zachary J.;
Eschrich, Steven A.;
Balagurunathan, Yoganand;
Goldof, Dmitry;
Aberle, Denise R.;
Gillies, Robert J.

Publication type:

Article

Collagen production and niche engineering: A novel strategy for cancer cells to survive acidosis in DCIS and evolve.

Published in:

Evolutionary Applications, 2020, v. 13, n. 10, p. 2689, doi. 10.1111/eva.13075

By:

Damaghi, Mehdi;
Mori, Hidetoshi;
Byrne, Samantha;
Xu, Liping;
Chen, Tingan;
Johnson, Joseph;
Gallant, Nathan D.;
Marusyk, Andriy;
Borowsky, Alexander D.;
Gillies, Robert J.

Publication type:

Article

AI-Radiomics Can Improve Inclusion Criteria and Clinical Trial Performance.

Published in:

Tomography: A Journal for Imaging Research, 2022, v. 8, n. 1, p. 341, doi. 10.3390/tomography8010028

By:

Tomaszewski, Michal R.;
Fan, Shuxuan;
Garcia, Alberto;
Qi, Jin;
Kim, Youngchul;
Gatenby, Robert A.;
Schabath, Matthew B.;
Tap, William D.;
Reinke, Denise K.;
Makanji, Rikesh J.;
Reed, Damon R.;
Gillies, Robert J.

Publication type:

Article

Deep Feature Stability Analysis Using CT Images of a Physical Phantom Across Scanner Manufacturers, Cartridges, Pixel Sizes, and Slice Thickness.

Published in:

Tomography: A Journal for Imaging Research, 2020, v. 6, n. 2, p. 250, doi. 10.18383/j.tom.2020.00003

By:

Paul, Rahul;
Shafiq-ul Hassan, Mohammed;
Moros, Eduardo G.;
Gillies, Robert J.;
Hall, Lawrence O.;
Goldgof, Dmitry B.

Publication type:

Article

Lung Nodule Sizes Are Encoded When Scaling CT Image for CNN's.

Published in:

Tomography: A Journal for Imaging Research, 2020, v. 6, n. 2, p. 209, doi. 10.18383/j.tom.2019.00024

By:

Cherezov, Dmitry;
Paul, Rahul;
Fetisov, Nikolai;
Gillies, Robert J.;
Schabath, Matthew B.;
Goldgof, Dmitry B.;
Hall, Lawrence O.

Publication type:

Article

Multisite Technical and Clinical Performance Evaluation of Quantitative Imaging Biomarkers from 3D FDG PET Segmentations of Head and Neck Cancer Images.

Published in:

Tomography: A Journal for Imaging Research, 2020, v. 6, n. 2, p. 65, doi. 10.18383/j.tom.2020.00004

By:

Smith, Brian J.;
Buatti, John M.;
Bauer, Christian;
Ulrich, Ethan J.;
Ahmadvand, Payam;
Budzevich, Mikalai M.;
Gillies, Robert J.;
Goldgof, Dmitry;
Grkovski, Milan;
Hamarneh, Ghassan;
Kinahan, Paul E.;
Muzi, John P.;
Muzi, Mark;
Laymon, Charles M.;
Mountz, James M.;
Nehmeh, Sadek;
Oborski, Matthew J.;
Binsheng Zhao;
Sunderland, John J.;
Beichel, Reinhard R.

Publication type:

Article

Multi-Window CT Based Radiological Traits for Improving Early Detection in Lung Cancer Screening.

Published in:

Cancer Management & Research, 2020, v. 12, p. 12225, doi. 10.2147/CMAR.S246609

By:

Lu, Hong;
Kim, Jongphil;
Qi, Jin;
Li, Qian;
Liu, Ying;
Schabath, Matthew B;
Ye, Zhaoxiang;
Gillies, Robert J;
Balagurunathan, Yoganand

Publication type:

Article

Lysosomal protein relocation as an adaptation mechanism to extracellular acidosis.

Published in:

Cell Cycle, 2016, v. 15, n. 13, p. 1659, doi. 10.1080/15384101.2016.1176394

By:

Damaghi, Mehdi;
Gillies, Robert J.

Publication type:

Article

Proton export upregulates aerobic glycolysis.

Published in:

BMC Biology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12915-022-01340-0

By:

Russell, Shonagh;
Xu, Liping;
Kam, Yoonseok;
Abrahams, Dominique;
Ordway, Bryce;
Lopez, Alex S.;
Bui, Marilyn M.;
Johnson, Joseph;
Epstein, Tamir;
Ruiz, Epifanio;
Lloyd, Mark C.;
Swietach, Pawel;
Verduzco, Daniel;
Wojtkowiak, Jonathan;
Gillies, Robert J.

Publication type:

Article

Cell Density Measurements in Hollow Fiber Bioreactors.

Published in:

Biotechnology Progress, 1988, v. 4, n. 4, p. 202, doi. 10.1002/btpr.5420040403

By:

Blute, Thomas;
Gillies, Robert J.;
Dale, Bruce E.

Publication type:

Article

[Ca2+]i and pHin Homeostasis in Kaposi Sarcoma Cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 1996, v. 6, n. 3, p. 169, doi. 10.1159/000154820

By:

Martínez-Zaguilán, Raul;
Chinnock, Brian F.;
Wald-Hopkins, Sarah;
Bernas, Mike;
Way, Dennis;
Weinand, Martin;
Witte, Marlys H.;
Gillies, Robert J.

Publication type:

Article

Glucose Decreases Intracellular Free Calcium and pH in Cultured Rat Aortic Vascular Smooth Muscle Cells: Role of Ca2+-ATPase.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 1995, v. 5, n. 5, p. 299, doi. 10.1159/000154766

By:

Wang, Xiaonan;
Lien, Yeong-Hau H.;
Gillies, Robert J.;
Martínez-Zaguilán, Raul

Publication type:

Article

Why do cancers have high aerobic glycolysis?

Published in:

Nature Reviews Cancer, 2004, v. 4, n. 11, p. 891, doi. 10.1038/nrc1478

By:

Gatenby, Robert A.;
Gillies, Robert J.

Publication type:

Article

L-DOS47 Elevates Pancreatic Cancer Tumor pH and Enhances Response to Immunotherapy.

Published in:

Biomedicines, 2024, v. 12, n. 2, p. 461, doi. 10.3390/biomedicines12020461

By:

Jardim-Perassi, Bruna Victorasso;
Irrera, Pietro;
Oluwatola, Oluwaseyi E.;
Abrahams, Dominique;
Estrella, Veronica C.;
Ordway, Bryce;
Byrne, Samantha R.;
Ojeda, Andrew A.;
Whelan, Christopher J.;
Kim, Jongphil;
Beatty, Matthew S.;
Damgaci-Erturk, Sultan;
Longo, Dario Livio;
Gaspar, Kim J.;
Siegers, Gabrielle M.;
Centeno, Barbara A.;
Lau, Justin Y. C.;
Pilon-Thomas, Shari A.;
Ibrahim-Hashim, Arig;
Gillies, Robert J.

Publication type:

Article

Delta radiomic features improve prediction for lung cancer incidence: A nested case–control analysis of the National Lung Screening Trial.

Published in:

Cancer Medicine, 2018, v. 7, n. 12, p. 6340, doi. 10.1002/cam4.1852

By:

Cherezov, Dmitry;
Hawkins, Samuel H.;
Goldgof, Dmitry B.;
Hall, Lawrence O.;
Liu, Ying;
Li, Qian;
Balagurunathan, Yoganand;
Gillies, Robert J.;
Schabath, Matthew B.

Publication type:

Article

Tris-base buffer: a promising new inhibitor for cancer progression and metastasis.

Published in:

Cancer Medicine, 2017, v. 6, n. 7, p. 1720, doi. 10.1002/cam4.1032

By:

Ibrahim‐Hashim, Arig;
Abrahams, Dominique;
Enriquez‐Navas, Pedro M.;
Luddy, Kim;
Gatenby, Robert A.;
Gillies, Robert J.

Publication type:

Article

Extracellular Acidification Induces Lysosomal Dysregulation.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1188, doi. 10.3390/cells10051188

By:

Ordway, Bryce;
Gillies, Robert J.;
Damaghi, Mehdi;
Isidoro, Ciro;
Jäättelä, Marja;
Sloane, Bonnie F.

Publication type:

Article

Current advances in mathematical modeling of anti-cancer drug penetration into tumor tissues.

Published in:

Frontiers in Oncology, 2013, v. 3, p. 1, doi. 10.3389/fonc.2013.00278

By:

Kim, MunJu;
Gillies, Robert J.;
Rejniak, Katarzyna A.

Publication type:

Article

Immunotherapy on acid: opportunities and challenges.

Published in:

2020

By:

Damgaci, Sultan;
Enriquez-Navas, Pedro M.;
Pilon-Thomas, Shari;
Guvenis, Albert;
Gillies, Robert J.;
Ibrahim-Hashim, Arig

Publication type:

journal article

Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation.

Published in:

International Journal of Cancer, 2017, v. 140, n. 6, p. 1331, doi. 10.1002/ijc.30540

By:

Avnet, Sofia;
Di Pompo, Gemma;
Chano, Tokuhiro;
Errani, Costantino;
Ibrahim‐Hashim, Arig;
Gillies, Robert J.;
Donati, Davide Maria;
Baldini, Nicola

Publication type:

Article

T-cells produce acidic niches in lymph nodes to suppress their own effector functions.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-17756-7

By:

Wu, Hao;
Estrella, Veronica;
Beatty, Matthew;
Abrahams, Dominique;
El-Kenawi, Asmaa;
Russell, Shonagh;
Ibrahim-Hashim, Arig;
Longo, Dario Livio;
Reshetnyak, Yana K.;
Moshnikova, Anna;
Andreev, Oleg A.;
Luddy, Kimberly;
Damaghi, Mehdi;
Kodumudi, Krithika;
Pillai, Smitha R.;
Enriquez-Navas, Pedro;
Pilon-Thomas, Shari;
Swietach, Pawel;
Gillies, Robert J.

Publication type:

Article

Quantitative Computed Tomographic Descriptors Associate Tumor Shape Complexity and Intratumor Heterogeneity with Prognosis in Lung Adenocarcinoma.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0118261

By:

Grove, Olya;
Berglund, Anders E.;
Schabath, Matthew B.;
Aerts, Hugo J. W. L.;
Dekker, Andre;
Wang, Hua;
Velazquez, Emmanuel Rios;
Lambin, Philippe;
Gu, Yuhua;
Balagurunathan, Yoganand;
Eikman, Edward;
Gatenby, Robert A.;
Eschrich, Steven;
Gillies, Robert J.

Publication type:

Article

Intermittent Hypoxia Selects for Genotypes and Phenotypes That Increase Survival, Invasion, and Therapy Resistance.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120958

By:

Verduzco, Daniel;
Lloyd, Mark;
Xu, Liping;
Ibrahim-Hashim, Arig;
Balagurunathan, Yoganand;
Gatenby, Robert A.;
Gillies, Robert J.

Publication type:

Article

Evaluation of the “Steal” Phenomenon on the Efficacy of Hypoxia Activated Prodrug TH-302 in Pancreatic Cancer.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0113586

By:

Bailey, Kate M.;
Cornnell, Heather H.;
Ibrahim-Hashim, Arig;
Wojtkowiak, Jonathan W.;
Hart, Charles P.;
Zhang, Xiaomeng;
Leos, Rafael;
Martinez, Gary V.;
Baker, Amanda F.;
Gillies, Robert J.

Publication type:

Article