Vaccines are one of the most important discoveries of humanity, being an effective intervention to protect the population against infectious diseases. When the Covid-19 vaccination campaign, the feat of Doctor Francisco Javier de Balmis y Berenguer in the "Royal Philanthropic Vaccine Expedition" is remembered due to the importance that vaccination has had over the years and mentioning that The National Vaccination Campaign against COVID-19 in Mexico began at the "Dr. Eduardo Liceaga" General Hospital of Mexico.