Works matching DE "DRUG solubility"

Results: 2979

Preparation and Characterization of Ternary Complexes to Improve the Solubility and Dissolution Performance of a Proteolysis-Targeting Chimera Drug.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 671, doi. 10.3390/pharmaceutics17050671

By:

Zhang, Heng;
Wu, Hengqian;
Wang, Lili;
Galarza, Laura Machín;
Wu, Chuanyu;
Li, Mingzhong;
Wang, Zhengping;
Zhou, Erpeng;
Han, Jun

Publication type:

Article

Biofunctional Excipients: Their Emerging Role in Overcoming the Inherent Poor Biopharmaceutical Characteristics of Drugs.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 598, doi. 10.3390/pharmaceutics17050598

By:

Qelliny, Milad Reda;
Mustafa, Wesam W.;
Fatease, Adel Al;
Alamri, Ali H.;
Alany, Raid;
Abdelkader, Hamdy

Publication type:

Article

Application of Theoretical Solubility Calculations and Thermal and Spectroscopic Measurements to Guide the Processing of Triamcinolone Acetonide by Hot-Melt Extrusion.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 586, doi. 10.3390/pharmaceutics17050586

By:

Granados, Pedro A.;
Gross, Idejan P.;
Medeiros-Souza, Patrícia;
Sá-Barreto, Livia L.;
Gelfuso, Guilherme M.;
Gratieri, Tais;
Cunha-Filho, Marcilio

Publication type:

Article

Influence of Ionization and the Addition of Cyclodextrins and Hydrophilic Excipients on the Solubility of Benzthiazide, Isoxicam, and Piroxicam.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 571, doi. 10.3390/pharmaceutics17050571

By:

Lucero-Borja, Diego;
Ruiz, Rebeca;
Fuguet, Elisabet;
Ràfols, Clara

Publication type:

Article

Formulation and Characterization of Chitosan Based Oral Nanoparticles of Poorly Water-Soluble Drug Lurasidone Hydrochloride.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2025, v. 59, p. s454, doi. 10.5530/ijper.20253872

By:

Gangane, Purushottam;
Ingle, Pallavi;
Rabade, Vijaya;
Sawarkar, Harigopal

Publication type:

Article

Acetoxy DMU-loaded carboxymethylchitosan nanocapsules: preparation and in vitro release evaluation followed by an analytical methodology validation.

Published in:

Soft Materials, 2022, v. 20, n. 2, p. 219, doi. 10.1080/1539445X.2021.1992426

By:

Jacumazo, Joslaine;
Perez, Carla C.;
Khalil, Najeh Maissar;
Almeida, Carlos Alberto Policiano

Publication type:

Article

Design and evaluation of sustained release hydrophilic matrix tablets of Piroxicam based on carboxymethyl xanthan derivatives.

Published in:

Soft Materials, 2021, v. 19, n. 2, p. 178, doi. 10.1080/1539445X.2020.1789994

By:

Yahoum, Madiha M.;
Lefnaoui, Sonia;
Moulai-Mostefa, Nadji

Publication type:

Article

Folic acid-modified β-cyclodextrin nanoparticles as drug delivery to load DOX for liver cancer therapeutics.

Published in:

Soft Materials, 2019, v. 17, n. 4, p. 437, doi. 10.1080/1539445X.2019.1624265

By:

Fan, Wenbo;
Xu, Yuedi;
Li, Zheng;
Li, Qiang

Publication type:

Article

Handling (Nano)Silver as Antimicrobial Agent: Therapeutic Window, Dissolution Dynamics, Detection Methods and Molecular Interactions.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 48, p. 10948, doi. 10.1002/chem.202002143

By:

Abram, Sarah‐Luise;
Fromm, Katharina M.

Publication type:

Article

Development of mesoporous magnetic nanoparticles supported idarubicin and investigation of apoptotic and cytotoxic effects on cancer cell lines.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09914-7

By:

Ulusal, Hasan;
Ulusal, Fatma;
Özdemir, Nalan

Publication type:

Article

Increase in the solubility of uvsY using a site saturation mutagenesis library for application in a lyophilized reagent for recombinase polymerase amplification.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09367-y

By:

Morimoto, Kenta;
Juma, Kevin Maafu;
Yamagata, Masaya;
Takita, Teisuke;
Kojima, Kenji;
Suzuki, Koichiro;
Yanagihara, Itaru;
Fujiwara, Shinsuke;
Yasukawa, Kiyoshi

Publication type:

Article

Counter‐intuitive discovery in the formulation of poorly water‐soluble drugs: Amorphous small‐molecule gels.

Published in:

Medicinal Research Reviews, 2024, v. 44, n. 6, p. 2624, doi. 10.1002/med.22060

By:

Shu, Yecheng;
Zhao, Peixu;
Li, Xin;
Shi, Xianbao;
Fu, Qiang

Publication type:

Article

Buccal delivery system of active pharmaceutical ingredients-ionic liquid (API-IL): Effects of API-IL loading and gelatin film concentration.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2024, v. 202, p. 115, doi. 10.1016/j.cherd.2023.12.027

By:

Ng, Liu Han;
Hadinoto, Kunn

Publication type:

Article

A high throughput approach of selecting excipients for solubility enhancement of BCS Class II active pharmaceutical ingredients for oral dosage forms.

Published in:

Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A, 2023, v. 193, p. 751, doi. 10.1016/j.cherd.2023.04.011

By:

Bahr, Matthew N.;
Matamoros, Sharon V.;
Campbell, Gossett A.

Publication type:

Article

A holistic continuum model-based approach to drug release.

Published in:

Continuum Mechanics & Thermodynamics, 2022, v. 34, n. 1, p. 81, doi. 10.1007/s00161-021-01046-8

By:

Morozova, Anna S.;
Vilchevskaya, Elena N.;
Müller, Wolfgang;
Bessonov, Nikolay M.

Publication type:

Article

Dimerization of aurein 1.2: effects in structure, antimicrobial activity and aggregation of Cândida albicans cells.

Published in:

Amino Acids, 2013, v. 44, n. 6, p. 1521, doi. 10.1007/s00726-013-1475-3

By:

Lorenzón, E.;
Sanches, P.;
Nogueira, L.;
Bauab, T.;
Cilli, E.

Publication type:

Article

Symbravo Mechanism of Action and Patient Selection, with PI Stewart Tepper, MD.

Published in:

Patient Care (Online), 2025, p. 1

By:

Tepper, Stewart

Publication type:

Article

Enhancement of Dissolution Rate of Piperine Using Solid Dispersion Approach and Evaluation of Its Antioxidant Activity.

Published in:

Trends in Sciences, 2025, v. 22, n. 1, p. 1, doi. 10.48048/tis.2024.8757

By:

Dewi, Rizna Triana;
Shiddiqi, Muhamad Fikri Ash;
Hapsari, Vidia;
Naulidia, Rifqah Azzahra;
Yuliani, Tri;
Angelina, Marissa;
Okselni, Tia;
Septama, Abdi Wira

Publication type:

Article

UTILIZATION OF NEAR-INFRARED SPECTROSCOPY COMBINED WITH PLS-2 REGRESSION LEARNER TO PREDICT METFORMIN HCL TABLET DISSOLUTION PROFILE.

Published in:

Eduvest: Journal Of Universal Studies, 2025, v. 5, n. 1, p. 882, doi. 10.59188/eduvest.v5i1.1566

By:

Zakaria, Mohamad Rahmatullah;
Sutriyo;
Hayun;
Rukmana, Taufiq Indra

Publication type:

Article

The Potential of Colloidal Systems Based on Carbamate-Containing Hexadecylpiperidinium Surfactants in Biomedical Applications.

Published in:

Colloids & Interfaces, 2024, v. 8, n. 5, p. 57, doi. 10.3390/colloids8050057

By:

Kushnazarova, Rushana;
Mirgorodskaya, Alla;
Bekrenev, Dmitry;
Kuznetsov, Denis;
Lyubina, Anna;
Voloshina, Alexandra;
Zakharova, Lucia

Publication type:

Article

Determination of Pterostilbene in Pharmaceutical Products Using a New HPLC Method and Its Application to Solubility and Stability Samples.

Published in:

Separations (2297-8739), 2023, v. 10, n. 3, p. 178, doi. 10.3390/separations10030178

By:

Haq, Nazrul;
Shakeel, Faiyaz;
Ghoneim, Mohammed M.;
Asdaq, Syed Mohammed Basheeruddin;
Alam, Prawez;
Aloatibi, Fahad Obaid;
Alshehri, Sultan

Publication type:

Article

Formulation and optimization of polymeric agglomerates of Bosentan monohydrate by crystallo-co-agglomeration technique.

Published in:

Bulletin of the National Research Centre, 2022, v. 46, n. 1, p. 1, doi. 10.1186/s42269-022-00837-6

By:

Varia, Umang;
Patel, Azad;
Katariya, Hitesh;
Detholia, Krunal

Publication type:

Article

配位滴定法测定锌含量的合适酸度条件研究.

Published in:

Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue, 2022, v. 12, n. 3, p. 145, doi. 10.3969/j.issn.2095-1035.2022.03.022

By:

苏铁军;
夏金强;
李克娥

Publication type:

Article

Silicone matrices for controlled dexamethasone release: toward a better understanding of the underlying mass transport mechanisms.

Published in:

Regenerative Biomaterials, 2023, v. 10, p. 1, doi. 10.1093/rb/rbad008

By:

Rongthong, Thitiphorn;
Qnouch, Adam;
Gehrke, Maria Maue;
Paccou, Laurent;
Oliveira, Paulo;
Danede, Florence;
Verin, Jeremy;
Vincent, Christophe;
Willart, Jean-Francois;
Siepmann, Florence;
Siepmann, Juergen

Publication type:

Article

Amorphous solid dispersion: a promising technique for improving oral bioavailability of poorly water-soluble drugs.

Published in:

SA Pharmaceutical Journal Incorporating Pharmacy Management, 2018, v. 85, n. 1, p. 50

By:

Ghule, Prashant;
Gilhotra, Ritu;
Jithan, Aukunuru;
Bairagi, Shripad;
Aher, Abhijeet

Publication type:

Article

Simulation and Optimization: A New Direction in Supercritical Technology Based Nanomedicine.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 12, p. 1404, doi. 10.3390/bioengineering10121404

By:

Huang, Yulan;
Zheng, Yating;
Lu, Xiaowei;
Zhao, Yang;
Zhou, Da;
Zhang, Yang;
Liu, Gang

Publication type:

Article

Systematic Screening Study for the Selection of Proper Stabilizers to Produce Physically Stable Canagliflozin Nanosuspension by Wet Milling Method.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 8, p. 927, doi. 10.3390/bioengineering10080927

By:

Pirincci Tok, Yagmur;
Mesut, Burcu;
Güngör, Sevgi;
Sarıkaya, Ali Osman;
Aldeniz, Emre Erol;
Dude, Udaya;
Özsoy, Yıldız

Publication type:

Article

TARTESSUS : A Customized Electrospun Drug Delivery System Loaded with Irinotecan for Local and Sustained Chemotherapy Release in Pancreatic Cancer.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 2, p. 183, doi. 10.3390/bioengineering10020183

By:

Cepeda-Franco, Carmen;
Mitxelena-Iribarren, Oihane;
Calero-Castro, Francisco José;
Astigarraga, Malen;
Castillo-Tuñon, Juan M.;
Laga, Iman;
Pereira, Sheila;
Arana, Sergio;
Mujika, Maite;
Padillo-Ruiz, Javier

Publication type:

Article

Polymeric liposomes of emtricitabine employing modified pullulan—an attempt to reduce associated hepatotoxicity.

Published in:

Journal of Liposome Research, 2024, v. 34, n. 4, p. 630, doi. 10.1080/08982104.2024.2362352

By:

Bhattacharyya, Sayani;
R, Lahari;
MK, Ranganath

Publication type:

Article

Assessments of in vitro and in vivo antineoplastic potentials of β-sitosterol-loaded PEGylated niosomes against hepatocellular carcinoma.

Published in:

Journal of Liposome Research, 2021, v. 31, n. 3, p. 304, doi. 10.1080/08982104.2020.1820520

By:

Nisha, Raquibun;
Kumar, Pranesh;
Gautam, Anurag Kumar;
Bera, Hriday;
Bhattacharya, Bolay;
Parashar, Poonam;
Saraf, Shubhini A.;
Saha, Sudipta

Publication type:

Article

Quality by design (Qbd) assisted development of phytosomal gel of aloe vera extract for topical delivery.

Published in:

Journal of Liposome Research, 2021, v. 31, n. 4, p. 381, doi. 10.1080/08982104.2020.1849279

By:

Jain, Pooja;
Taleuzzaman, Mohamad;
Kala, Chandra;
Kumar Gupta, Dipak;
Ali, Asad;
Aslam, Mohammed

Publication type:

Article

Novel Vitamin E TPGS based docetaxel nanovesicle formulation for its safe and effective parenteral delivery: Toxicological, pharmacokinetic and pharmacodynamic evaluation.

Published in:

Journal of Liposome Research, 2021, v. 31, n. 4, p. 365, doi. 10.1080/08982104.2020.1835955

By:

Singh, Amrinder;
Thakur, Shubham;
Singh, Harmanpreet;
Singh, Harjeet;
Kaur, Sandeep;
Kaur, Satwinderjeet;
Dudi, Rajesh;
Mondhe, Dilip Manikrao;
Jain, Subheet Kumar

Publication type:

Article

Potential role of resveratrol-loaded elastic sorbitan monostearate nanovesicles for the prevention of UV-induced skin damage.

Published in:

Journal of Liposome Research, 2020, v. 30, n. 1, p. 45, doi. 10.1080/08982104.2019.1580721

By:

Abbas, Haidy;
Kamel, Rabab

Publication type:

Article

Design of a liquid nano-sized drug delivery system with enhanced solubility of rivaroxaban for venous thromboembolism management in paediatric patients and emergency cases.

Published in:

Journal of Liposome Research, 2019, v. 29, n. 4, p. 399, doi. 10.1080/08982104.2019.1576732

By:

Abouhussein, Dalia M. N.;
Bahaa El Din Mahmoud, Dina;
Mohammad F., Ebtehal

Publication type:

Article

Formulation development of self-nanoemulsifying drug delivery system of celecoxib for the management of oral cavity inflammation.

Published in:

Journal of Liposome Research, 2019, v. 29, n. 2, p. 195, doi. 10.1080/08982104.2018.1524484

By:

Salem, Heba F.;
Kharshoum, Rasha M.;
Sayed, Ossama M.;
Abdel Hakim, Lekaa F.

Publication type:

Article

Formulation and optimization of solid lipid nanoparticles of buspirone HCl for enhancement of its oral bioavailability.

Published in:

Journal of Liposome Research, 2010, v. 20, n. 4, p. 286, doi. 10.3109/08982100903443065

By:

Varshosaz, Jaleh;
Tabbakhian, Majid;
Mohammadi, Mahboobeh Y.

Publication type:

Article

Lipophilic Drug Transfer Between Liposomal and Biological Membranes: What Does It Mean for Parenteral and Oral Drug Delivery?

Published in:

Journal of Liposome Research, 2006, v. 16, n. 3, p. 281, doi. 10.1080/08982100600848702

By:

Fahr, Alfred;
van Hoogevest, Peter;
Kuntsche, Judith;
Leigh, Mathew L. S.

Publication type:

Article

Mechanisms of intestinal pharmacokinetic natural product-drug interactions.

Published in:

Drug Metabolism Reviews, 2024, v. 56, n. 3, p. 285, doi. 10.1080/03602532.2024.2386597

By:

Oyanna, Victoria O.;
Clarke, John D.

Publication type:

Article

The metabolic effect of gut microbiota on drugs.

Published in:

Drug Metabolism Reviews, 2020, v. 52, n. 1, p. 139, doi. 10.1080/03602532.2020.1718691

By:

Xie, Yuan;
Hu, Fangdi;
Xiang, Dawei;
Lu, Hui;
Li, Wenbin;
Zhao, Anpeng;
Huang, Longji;
Wang, Rong

Publication type:

Article

Toward a better understanding of metabolic and pharmacokinetic characteristics of low-solubility, low-permeability natural medicines.

Published in:

Drug Metabolism Reviews, 2020, v. 52, n. 1, p. 19, doi. 10.1080/03602532.2020.1714646

By:

Yang, Jie;
Li, Kailing;
He, Dan;
Gu, Jing;
Xu, Jingyu;
Xie, Jiaxi;
Zhang, Min;
Liu, Yuying;
Tan, Qunyou;
Zhang, Jingqing

Publication type:

Article

Difference and alteration in pharmacokinetic and metabolic characteristics of low-solubility natural medicines.

Published in:

Drug Metabolism Reviews, 2018, v. 50, n. 2, p. 140, doi. 10.1080/03602532.2018.1430823

By:

Yan, Shenglei;
Liu, Yuying;
Feng, Jianfang;
Zhao, Hua;
Yu, Zhongshu;
Zhao, Jing;
Li, Yao;
Zhang, Jingqing

Publication type:

Article

Glucuronidation: driving factors and their impact on glucuronide disposition.

Published in:

Drug Metabolism Reviews, 2017, v. 49, n. 2, p. 105, doi. 10.1080/03602532.2017.1293682

By:

Yang, Guangyi;
Ge, Shufan;
Singh, Rashim;
Basu, Sumit;
Shatzer, Katherine;
Zen, Ming;
Liu, Jiong;
Tu, Yifan;
Zhang, Chenning;
Wei, Jinbao;
Shi, Jian;
Zhu, Lijun;
Liu, Zhongqiu;
Wang, Yuan;
Gao, Song;
Hu, Ming

Publication type:

Article

SCIENTOMETRIC REVIEW OF TABLET SUPER-DISINTEGRANTS.

Published in:

Journal of Pharmaceutical & Allied Sciences, 2023, v. 20, n. 3, p. 3943

By:

BAKO, WUNIA'H;
ZAKKA, PAUL W.;
S., OKAFOR IGNATIUS

Publication type:

Article

Preparation and evaluation of biological activity of ZSM-5 nanoparticles loaded with gefitinib for the treatment of non-small cell lung carcinoma.

Published in:

Pharmacia (0428-0296), 2024, v. 71, n. 1, p. 1, doi. 10.3897/pharmacia.71.e112449

By:

Al-Sahlawi, Farah;
Al-Ani, Israa;
El-Tanani, Mohamed;
Farooq, Hafiz Aadil

Publication type:

Article

A novel formulation of ketoconazole entrapped in alginate with anionic polymer beads for solubility enhancement: Preparation and characterization.

Published in:

Pharmacia (0428-0296), 2023, v. 70, n. 4, p. 1423, doi. 10.3897/pharmacia.70.e108120

By:

Annisa, Viviane;
Saifullah Sulaiman, Teuku Nanda;
Nugroho, Akhmad Kharis;
Nugroho, Agung Endro

Publication type:

Article

Environmental friendly carrier material for nifedipine as hypertension drug.

Published in:

Global Journal of Environmental Science & Management (GJESM), 2020, v. 6, n. 4, p. 523, doi. 10.22034/gjesm.2020.04.08

By:

Budianto, E.;
Astuti, S. H.

Publication type:

Article

DESIGN AND EVALUATION OF SELF-NANO EMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS) OF A BCS CLASS II ANTIHYPERTENSIVE DRUG.

Published in:

International Journal of Chemical & Pharmaceutical Analysis, 2018, v. 6, n. 1, p. 1

By:

Khutle, Nilesh Mahadeo;
Pawar, Harshal Ashok;
Doke, Vishakha Vishwanath;
Joshi, Laxmi Shashidhar

Publication type:

Article

LIQUISOLID COMPACT: A NOVEL APPROACH TO ENHANCE SOLUBILITY AND DISSOLUTION RATE.

Published in:

International Journal of Chemical & Pharmaceutical Analysis, 2015, v. 3, n. 1, p. 1

By:

Gorde, Nilesh;
Kale, Mohan;
Waghulde, Sandeep;
Naik, Pravin

Publication type:

Article

ANTIMICROBIAL EFFICACY OF INTERCANAL MEDICAMENTS AGAINST A MATURE MULTI-SPICIES BIOFILM MODEL: AN EX-VIVO STUDY.

Published in:

International Arab Journal of Dentistry, 2024, v. 15, n. 1, p. 57, doi. 10.70174/iajd.v15i1.959

By:

Zakaria, Nada;
Nagy, Mohamed Mokhtar;
Elhady, Soha;
Saber, Shehabeldin

Publication type:

Article

6种常用抗寄生虫药在鸡的生物药剂学分类研究.

Published in:

Journal of Nanjing Agricultural University / Nanjuing Nongye Daxue Xuebao, 2020, v. 43, n. 5, p. 919, doi. 10.7685/jnau.201912014

By:

李香秀;
王玥;
孙乃岩;
刘洋;
黄金虎;
樊萍;
王丽平

Publication type:

Article