Results
Title

The Correlation Between Sperm DNA Integrity and Conventional Semen Parameters.

Authors

Khalaf, Narges Mohsen; Mohammed, Amal Abdulwahid; Rahim, Ali Ibrahim

Abstract

The integrity of sperm deoxyribonucleic acid (DNA) and chromatin is very important for genetic material transmission into offspring. Therefore, the aim of the present study was to investigate the correlation between sperm deoxyribonucleic acid integrity and sperm parameters. The current study was conducted on 96 semen samples. This study was done at the High Institute for Infertility Diagnosis and Assisted Reproductive Technologies, Al-Nahrain University for the period between November 2020 and May 2021. The samples were collected, and seminal fluid analysis was performed according to World Health Organization guidelines. Sperm Chromatin Dispersion test was performed. The results showed that the deoxyribonucleic acid fragmentation of sperms in infertile men in this study was higher than reported in fertile men in previous studies indicating that deoxyribonucleic acid fragmentation (DNA) is actively contributing at least partially to male infertility. In terms of enrolled men, sperm deoxyribonucleic acid fragmentation (SDF) showed significant positive correlation with round cell count.

Subjects

WORLD Health Organization; SEMEN; SPERMATOZOA; Y chromosome; DNA; REPRODUCTIVE technology; MALE infertility

Publication

Iraqi Journal of Embryos & Infertility Researches, 2022, Vol 11, Issue 1, p1

ISSN

2218-0265

Publication type

Academic Journal

DOI

10.28969/IJEIR.v11.i1.r1