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- Title
Distinguishing between primary infection and reinfection with rubella vaccine virus by IgG avidity assay in pregnant women.
- Authors
Hamkar, R.; Jalilvand, S.; Abdolbaghi, M. H.; Jelyani, K. N.; Esteghamati, A.; Hagh-goo, A.; Mohktari-Azad, T.; Nategh, R.
- Abstract
During the mass measles/rubella vaccination campaign in 2003 in Iran, many pregnant women were vaccinated mistakenly or became pregnant within 1 month of vaccination. To distinguish pregnant women who were affected by rubella vaccine as primary infection from those who had rubella reinfection from the vaccine, serum samples were collected 1-3 months after the campaign from 812 pregnant women. IgG avidity assay showed that 0.3% of the women had no rubella-specific IgG response; 14.4% had low-avidity anti-rubella IgG and were therefore not immune to rubella before vaccination; 85.3% had high-avidity anti-rubella IgG and were regarded as cases of reinfection.
- Subjects
IRAN; RUBELLA vaccines; IMMUNOGLOBULIN G; MEASLES vaccines; PREGNANT women; VACCINATION
- Publication
Eastern Mediterranean Health Journal, 2009, Vol 15, Issue 1, p94
- ISSN
1020-3397
- Publication type
Academic Journal
- DOI
10.26719/2009.15.1.94