Works matching DE "BROMODOMAIN-containing proteins"

Results: 256
    1
    2
    3

    A Chemical Probe for the ATAD2 Bromodomain.

    Published in:
    Angewandte Chemie, 2016, v. 128, n. 38, p. 11554, doi. 10.1002/ange.201603928
    By:
    • Bamborough, Paul;
    • Chung, Chun ‐ wa;
    • Demont, Emmanuel H.;
    • Furze, Rebecca C.;
    • Bannister, Andrew J.;
    • Che, Ka Hing;
    • Diallo, Hawa;
    • Douault, Clement;
    • Grandi, Paola;
    • Kouzarides, Tony;
    • Michon, Anne ‐ Marie;
    • Mitchell, Darren J.;
    • Prinjha, Rab K.;
    • Rau, Christina;
    • Robson, Samuel;
    • Sheppard, Robert J.;
    • Upton, Richard;
    • Watson, Robert J.
    Publication type:
    Article
    4

    LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.

    Published in:
    Angewandte Chemie, 2015, v. 127, n. 21, p. 6315, doi. 10.1002/ange.201501394
    By:
    • Clark, Peter G. K.;
    • Vieira, Lucas C. C.;
    • Tallant, Cynthia;
    • Fedorov, Oleg;
    • Singleton, Dean C.;
    • Rogers, Catherine M.;
    • Monteiro, Octovia P.;
    • Bennett, James M.;
    • Baronio, Roberta;
    • Müller, Susanne;
    • Daniels, Danette L.;
    • Méndez, Jacqui;
    • Knapp, Stefan;
    • Brennan, Paul E.;
    • Dixon, Darren J.
    Publication type:
    Article
    5

    A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction.

    Published in:
    Angewandte Chemie, 2014, v. 126, n. 24, p. 6240, doi. 10.1002/ange.201402750
    By:
    • Rooney, Timothy P. C.;
    • Filippakopoulos, Panagis;
    • Fedorov, Oleg;
    • Picaud, Sarah;
    • Cortopassi, Wilian A.;
    • Hay, Duncan A.;
    • Martin, Sarah;
    • Tumber, Anthony;
    • Rogers, Catherine M.;
    • Philpott, Martin;
    • Wang, Minghua;
    • Thompson, Amber L.;
    • Heightman, Tom D.;
    • Pryde, David C.;
    • Cook, Andrew;
    • Paton, Robert S.;
    • Müller, Susanne;
    • Knapp, Stefan;
    • Brennan, Paul E.;
    • Conway, Stuart J.
    Publication type:
    Article
    6
    7
    8
    9
    10

    Maintenance of macrophage transcriptional rograms and intestinal homeostasis by epigenetic reader SP140.

    Published in:
    Science Immunology, 2017, v. 2, n. 9, p. 1, doi. 10.1126/sciimmunol.aag3160
    By:
    • Mehta, Stuti;
    • Cronkite, D. Alexander;
    • Basavappa, Megha;
    • Saunders, Tahnee L.;
    • Adiliaghdam, Fatemeh;
    • Amatullah, Hajera;
    • Morrison, Sara A.;
    • Pagan, Jose D.;
    • Anthony, Robert M.;
    • Tonnerre, Pierre;
    • Lauer, Georg M.;
    • Lee, James C.;
    • Digumarthi, Sreehaas;
    • Pantano, Lorena;
    • Ho Sui, Shannan J.;
    • Fei Ji;
    • Sadreyev, Ruslan;
    • Chan Zhou;
    • Mullen, Alan C.;
    • Kumar, Vinod
    Publication type:
    Article
    11
    12
    13
    14
    15

    Two faces of BRD4.

    Published in:
    Transcription (2154-1264), 2013, v. 4, n. 1, p. 13, doi. 10.4161/trns.22542
    By:
    • Devaiah, Ballachanda N.;
    • Singer, Dinah S.
    Publication type:
    Article
    16
    17
    18

    Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.

    Published in:
    Nature Medicine, 2015, v. 21, n. 10, p. 1163, doi. 10.1038/nm.3952
    By:
    • Mazur, Pawel K;
    • Herner, Alexander;
    • Mello, Stephano S;
    • Wirth, Matthias;
    • Hausmann, Simone;
    • Sánchez-Rivera, Francisco J;
    • Lofgren, Shane M;
    • Kuschma, Timo;
    • Hahn, Stephan A;
    • Vangala, Deepak;
    • Trajkovic-Arsic, Marija;
    • Gupta, Aayush;
    • Heid, Irina;
    • Noël, Peter B;
    • Braren, Rickmer;
    • Erkan, Mert;
    • Kleeff, Jörg;
    • Sipos, Bence;
    • Sayles, Leanne C;
    • Heikenwalder, Mathias
    Publication type:
    Article
    19

    Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.

    Published in:
    Nature Medicine, 2014, v. 20, n. 7, p. 732, doi. 10.1038/nm.3613
    By:
    • Tang, Yujie;
    • Gholamin, Sharareh;
    • Schubert, Simone;
    • Willardson, Minde I;
    • Lee, Alex;
    • Bandopadhayay, Pratiti;
    • Bergthold, Guillame;
    • Masoud, Sabran;
    • Nguyen, Brian;
    • Vue, Nujsaubnusi;
    • Balansay, Brianna;
    • Yu, Furong;
    • Oh, Sekyung;
    • Woo, Pamelyn;
    • Chen, Spenser;
    • Ponnuswami, Anitha;
    • Monje, Michelle;
    • Atwood, Scott X;
    • Whitson, Ramon J;
    • Mitra, Siddhartha
    Publication type:
    Article
    20
    21
    22

    Papillomavirus-Associated Tumor Formation Critically Depends on c-Fos Expression Induced by Viral Protein E2 and Bromodomain Protein Brd4.

    Published in:
    PLoS Pathogens, 2016, v. 12, n. 1, p. 1, doi. 10.1371/journal.ppat.1005366
    By:
    • Delcuratolo, Maria;
    • Fertey, Jasmin;
    • Schneider, Markus;
    • Schuetz, Johanna;
    • Leiprecht, Natalie;
    • Hudjetz, Benjamin;
    • Brodbeck, Stephan;
    • Corall, Silke;
    • Dreer, Marcel;
    • Schwab, Roxana Michaela;
    • Grimm, Martin;
    • Wu, Shwu-Yuan;
    • Stubenrauch, Frank;
    • Chiang, Cheng-Ming;
    • Iftner, Thomas
    Publication type:
    Article
    23

    An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression.

    Published in:
    PLoS Pathogens, 2015, v. 11, n. 7, p. 1, doi. 10.1371/journal.ppat.1005063
    By:
    • Darcis, Gilles;
    • Kula, Anna;
    • Bouchat, Sophie;
    • Fujinaga, Koh;
    • Corazza, Francis;
    • Ait-Ammar, Amina;
    • Delacourt, Nadège;
    • Melard, Adeline;
    • Kabeya, Kabamba;
    • Vanhulle, Caroline;
    • Van Driessche, Benoit;
    • Gatot, Jean-Stéphane;
    • Cherrier, Thomas;
    • Pianowski, Luiz F.;
    • Gama, Lucio;
    • Schwartz, Christian;
    • Vila, Jorge;
    • Burny, Arsène;
    • Clumeck, Nathan;
    • Moutschen, Michel
    Publication type:
    Article
    24
    25
    26
    27
    28
    29
    30
    31

    BET inhibitor resistance emerges from leukaemia stem cells.

    Published in:
    Nature, 2015, v. 525, n. 7570, p. 538, doi. 10.1038/nature14888
    By:
    • Fong, Chun Yew;
    • Gilan, Omer;
    • Lam, Enid Y. N.;
    • Rubin, Alan F.;
    • Ftouni, Sarah;
    • Tyler, Dean;
    • Stanley, Kym;
    • Sinha, Devbarna;
    • Yeh, Paul;
    • Morison, Jessica;
    • Giotopoulos, George;
    • Lugo, Dave;
    • Jeffrey, Philip;
    • Lee, Stanley Chun-Wei;
    • Carpenter, Christopher;
    • Gregory, Richard;
    • Ramsay, Robert G.;
    • Lane, Steven W.;
    • Abdel-Wahab, Omar;
    • Kouzarides, Tony
    Publication type:
    Article
    32

    Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.

    Published in:
    Nature, 2015, v. 525, n. 7570, p. 543, doi. 10.1038/nature14898
    By:
    • Rathert, Philipp;
    • Roth, Mareike;
    • Neumann, Tobias;
    • Muerdter, Felix;
    • Roe, Jae-Seok;
    • Muhar, Matthias;
    • Deswal, Sumit;
    • Cerny-Reiterer, Sabine;
    • Peter, Barbara;
    • Jude, Julian;
    • Hoffmann, Thomas;
    • Boryń, Łukasz M.;
    • Axelsson, Elin;
    • Schweifer, Norbert;
    • Tontsch-Grunt, Ulrike;
    • Dow, Lukas E.;
    • Gianni, Davide;
    • Pearson, Mark;
    • Valent, Peter;
    • Stark, Alexander
    Publication type:
    Article
    33
    34
    35
    36
    37

    Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery.

    Published in:
    Epigenetics & Chromatin, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13072-015-0026-4
    By:
    • Zhan, Yanai;
    • Kost-Alimova, Maria;
    • Xi Shi;
    • Leo, Elisabetta;
    • Bardenhagen, Jennifer P.;
    • Shepard, Hannah E.;
    • Appikonda, Srikanth;
    • Vangamudi, Bhavatarini;
    • Zhao, Shuping;
    • Tieu, Trang N.;
    • Jiang, Shiming;
    • Heffernan, Timothy P.;
    • Marszalek, Joseph R.;
    • Toniatti, Carlo;
    • Draetta, Giulio;
    • Tyler, Jessica;
    • Barton, Michelle;
    • Jones, Philip;
    • Palmer, Wylie S.;
    • Geck Do, Mary K.
    Publication type:
    Article
    38

    Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery.

    Published in:
    Epigenetics & Chromatin, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13072-015-0026-4
    By:
    • Zhan, Yanai;
    • Kost-Alimova, Maria;
    • Xi Shi;
    • Leo, Elisabetta;
    • Bardenhagen, Jennifer P.;
    • Shepard, Hannah E.;
    • Appikonda, Srikanth;
    • Vangamudi, Bhavatarini;
    • Shuping Zhao;
    • Tieu, Trang N.;
    • Shiming Jiang;
    • Heffernan, Timothy P.;
    • Marszalek, Joseph R.;
    • Toniatti, Carlo;
    • Draetta, Giulio;
    • Tyler, Jessica;
    • Barton, Michelle;
    • Jones, Philip;
    • Palmer, Wylie S.;
    • Geck Do, Mary K.
    Publication type:
    Article
    39
    40
    41
    42

    BRD4 Short Isoform Interacts with RRP1B, SIPA1 and Components of the LINC Complex at the Inner Face of the Nuclear Membrane.

    Published in:
    PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080746
    By:
    • Alsarraj, Jude;
    • Faraji, Farhoud;
    • Geiger, Thomas R.;
    • Mattaini, Katherine R.;
    • Williams, Mia;
    • Wu, Josephine;
    • Ha, Ngoc-Han;
    • Merlino, Tyler;
    • Walker, Renard C.;
    • Bosley, Allen D.;
    • Xiao, Zhen;
    • Andresson, Thorkell;
    • Esposito, Dominic;
    • Smithers, Nicholas;
    • Lugo, Dave;
    • Prinjha, Rab;
    • Day, Anup;
    • Crawford, Nigel P. S.;
    • Ozato, Keiko;
    • Gardner, Kevin
    Publication type:
    Article
    43
    44
    45
    46
    47

    A Comparative Study of Fluorescence Assays in Screening for BRD4.

    Published in:
    Assay & Drug Development Technologies, 2018, v. 16, n. 7, p. 372, doi. 10.1089/adt.2018.850
    By:
    • Hansson, Pia;
    • Boyd, Helen;
    • Dale, Ian L.;
    • Dahl, Göran;
    • Nicolaus, Felix;
    • Bowen, Wayne;
    • Doering, Klaus;
    • Dunsmore, Colin;
    • Cotton, Graham;
    • Lindmark, Helena
    Publication type:
    Article
    48

    Literature Search and Review.

    Published in:
    Assay & Drug Development Technologies, 2017, v. 15, n. 5, p. 190, doi. 10.1089/adt.2017.29060.lit
    By:
    • Simeonov, Anton;
    • Davis, Mindy I.;
    • Auld, Doug
    Publication type:
    Article
    49
    50

    The Role of BPTF in Melanoma Progression and in Response to BRAF-Targeted Therapy.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2015, v. 107, n. 5, p. 1, doi. 10.1093/jnci/djv034
    By:
    • Dar, Altaf A.;
    • Nosrati, Mehdi;
    • Bezrookove, Vladimir;
    • de Semir, David;
    • Majid, Shahana;
    • Thummala, Suresh;
    • Sun, Vera;
    • Tong, Schuyler;
    • Leong, Stanley P. L.;
    • Minor, David;
    • Billings, Paul R.;
    • Soroceanu, Liliana;
    • Debs, Robert;
    • Miller III, James R.;
    • Sagebiel, Richard W.;
    • Kashani-Sabet, Mohammed
    Publication type:
    Article