Works matching DE "CELLULAR signal transduction"

Results: 5000

Recent advancements of betulinic acid-based drug delivery systems for cancer therapy (2002–2023).

Published in:

Natural Product Research, 2025, v. 39, n. 11, p. 3260, doi. 10.1080/14786419.2024.2412838

By:

Morparia, Saurabh;
Metha, Chaitanya;
Suvarna, Vasanti

Publication type:

Article

Chemical characterisation of essential oil from Sambucus williamsii Hance leaves and its hepatoprotective effects.

Published in:

Natural Product Research, 2025, v. 39, n. 11, p. 3111, doi. 10.1080/14786419.2024.2327637

By:

Meng, Xianqun;
Wang, Dan;
Hu, Qiushi;
Liang, Shanshan;
Wei, Qing;
Kang, Tingguo;
Meng, Xiansheng

Publication type:

Article

MST1 modulates inflammatory responses by targeting the NF-κB/NLRP3 pathway in LPS-induced acute lung injury.

Published in:

Histochemistry & Cell Biology, 2025, v. 163, n. 1, p. 1, doi. 10.1007/s00418-025-02383-4

By:

Peng, Zi-xi;
Song, Lin-li;
Wang, Xiao-Li

Publication type:

Article

基于网络药理学及分子对接探究马齿苋缓解肉兔肠炎的作用机制.

Published in:

China Herbivore Science, 2025, v. 45, n. 3, p. 29, doi. 10.3969/j.issn.2095-3887.2024.00.126

By:

谢浦航;
张子儒;
唐晓琴;
张贝贝;
邱彦博;
佘木子;
孙秀柱

Publication type:

Article

RUNX2 is essential for maintaining synchondrosis chondrocytes and cranial base growth.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-025-00426-z

By:

Hallett, Shawn A.;
Dixon, Ashley;
Marrale, Isabella;
Batoon, Lena;
Brenes, José;
Zhou, Annabelle;
Arbiv, Ariel;
Kaartinen, Vesa;
Allen, Benjamin;
Ono, Wanida;
Franceschi, Renny T.;
Ono, Noriaki

Publication type:

Article

Increased STAT3 Phosphorylation in CD4 + T-Cells of Treated Patients with Chronic Lymphocytic Leukemia and Changes in Circulating Regulatory T-Cell Subsets Relative to Tumor Mass Distribution Value and Disease Duration.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1204, doi. 10.3390/biomedicines13051204

By:

Dreisinger, Mojca;
Roškar, Zlatko;
Goropevšek, Aleš;
Zakelšek, Andreja;
Čurič, Sara;
Živko, Nada;
Bevc, Sebastjan;
Homšak, Evgenija

Publication type:

Article

The Regulation of the NF-κB p65 and Nrf2/HO-1 Signaling Pathways by Fucoxanthin in Human THP-1 Monocyte Macrophages Under a Lipopolysaccharide-Induced Inflammation Model.

Published in:

Foods, 2025, v. 14, n. 10, p. 1746, doi. 10.3390/foods14101746

By:

Zhang, Linyi;
Li, Tong;
Liu, Jingyi;
Sun, Jiyan;
Niu, Jinkun;
Ren, Dandan;
Ma, Yichao;
He, Yunhai;
Liu, Shu;
Wang, Qiukuan

Publication type:

Article

Stachydrine from Natural Foods Alleviates Hyperuricemia by Modulating Renal Urate Transporters and Suppressing Mitochondrial Oxidative Stress.

Published in:

Foods, 2025, v. 14, n. 10, p. 1718, doi. 10.3390/foods14101718

By:

Guo, Jian;
Jia, Jinhui;
Wang, Ailin;
Gu, Yunqi;
Xia, Xiaodong

Publication type:

Article

Correction to "miR‐223 Improves Intestinal Inflammation Through Inhibiting the IL‐6/STAT3 Signaling Pathway in Dextran Sodium Sulfate‐Induced Experimental Colitis".

Published in:: Immunity, Inflammation & Disease, 2025, v. 13, n. 5, p. 1, doi. 10.1002/iid3.70209
Publication type:: Article

Correction: Chen et al. Metabolomics-Based Study on the Anticonvulsant Mechanism of Acorus tatarinowii : GABA Transaminase Inhibition Alleviates PTZ-Induced Epilepsy in Rats. Metabolites 2025, 15 , 175.

Published in:

2025

By:

Chen, Liang;
Li, Jiaxin;
Fang, Chengwei;
Wang, Jiepeng

Publication type:

Correction Notice

Baicalin Alleviates Piglet Immunosuppression Induced by Glaesserella parasuis via Promoting CD163/Tumor Necrosis Factor-like Weak Inducer of Apoptosis-Mediated Autophagy.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 722, doi. 10.3390/biom15050722

By:

Fu, Shulin;
Luo, Ronghui;
Li, Jingyang;
Fu, Yunjian;
Dong, Qiaoli;
Liu, Siyu;
Sun, Yamin;
Guo, Ling;
Hu, Jin;
Qiu, Yinsheng

Publication type:

Article

PI3K/mTOR Signaling Pathway Dual Inhibition for the Management of Neuroinflammation: Novel Insights from In Vitro Models.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 677, doi. 10.3390/biom15050677

By:

Ardizzone, Alessio;
Scuderi, Sarah Adriana;
Casili, Giovanna;
Basilotta, Rossella;
Esposito, Emanuela;
Lanza, Marika

Publication type:

Article

The Critical Balance Between Quiescence and Reactivation of Neural Stem Cells.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 672, doi. 10.3390/biom15050672

By:

Elkin, Adam M.;
Robbins, Sarah;
Barros, Claudia S.;
Bossing, Torsten

Publication type:

Article

Baicalin Relieves Glaesserella parasuis -Triggered Immunosuppression Through Polarization via MIF/CD74 Signaling Pathway in Piglets.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 640, doi. 10.3390/biom15050640

By:

Fu, Shulin;
Dong, Qiaoli;
Fu, Yunjian;
Luo, Ronghui;
Li, Jingyang;
Sun, Yamin;
Liu, Siyu;
Qiu, Yinsheng;
Guo, Ling;
Hu, Jin

Publication type:

Article

Chartarlactams U-X: Novel Phenylspirodrimanes from a Marine Derived Fungus Stachybotrys sp. SZU-W23 with Anti-Inflammatory Activity Mediated by the NF-κB/ROS Signaling Pathways.

Published in:

Marine Drugs, 2025, v. 23, n. 5, p. 216, doi. 10.3390/md23050216

By:

Wu, Yanhua;
Lu, Lanyi;
Zhang, Peng;
Wang, Liyan

Publication type:

Article

Retraction notice: "MicroRNA-199a Inhibits Cell Proliferation, Migration, and Invasion and Activates AKT/mTOR Signaling Pathway by Targeting B7-H3 in Cervical Cancer".

Published in:: 2025
Publication type:: Correction Notice

Ampelopsis japonica enhances the effect of radiotherapy in non-small cell lung cancer.

Published in:

Strahlentherapie und Onkologie, 2025, v. 201, n. 6, p. 627, doi. 10.1007/s00066-024-02322-7

By:

Liu, Zhaohua;
Cui, Peixia;
Wu, Qian;
Ji, Xiao

Publication type:

Article

Ceramides as the molecular link between impaired lipid metabolism, saturated fatty acid intake and insulin resistance: are all saturated fatty acids to be blamed for ceramide-mediated lipotoxicity?

Published in:

Nutrition Research Reviews, 2025, v. 38, n. 1, p. 256, doi. 10.1017/S0954422424000179

By:

Sergi, Domenico;
Zauli, Enrico;
Celeghini, Claudio;
Previati, Maurizio;
Zauli, Giorgio

Publication type:

Article

RETRACTION NOTE: MIR-195 ALLEVIATES ULCERATIVE COLITIS IN RATS VIA MAPK SIGNALING PATHWAY.

Published in:: European Review for Medical & Pharmacological Sciences, 2025, v. 29, n. 5, p. 221
Publication type:: Article

Integrating network pharmacology, quantitative transcriptomic analysis, and experimental validation revealed the mechanism of cordycepin in the treatment of obesity.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1571480

By:

Liao, Yu;
Wang, Mingchao;
Qin, Fuli;
Liu, Taotao;
Chen, Jiemei

Publication type:

Article

Sphingosine 1-phosphate receptor 1 modulators exert neuroprotective effects in central nervous system disorders.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1516991

By:

Chen, Shouming;
Wu, Lan;
Lang, Bingchen;
Zhao, Guoyan;
Zhang, Wensheng

Publication type:

Article

Effect of Ochratoxin A (OTA) on the Immune System: A Systematic Review.

Published in:

Toxins, 2025, v. 17, n. 5, p. 256, doi. 10.3390/toxins17050256

By:

Mubarik, Yusif;
Boyetey, Shadrach Tetteh;
Aikins, Anastasia Rosebud;
Mutocheluh, Mohamed

Publication type:

Article

Unraveling the Transcriptomic Profiles of Large and Small Donkey Follicles.

Published in:

Genes, 2025, v. 16, n. 5, p. 602, doi. 10.3390/genes16050602

By:

Wang, Yanping;
Gao, Zihao;
Zhang, Qiang;
Guo, Xuchuan;
Xia, Wei;
Gu, Xinli;
Zeng, Weibin

Publication type:

Article

Signaling Pathways in Gliomas.

Published in:

Genes, 2025, v. 16, n. 5, p. 600, doi. 10.3390/genes16050600

By:

Stachyra, Paulina;
Grzybowska-Szatkowska, Ludmiła

Publication type:

Article

Altered miRNA Signatures in Follicular Fluid: Insights into Infertility Etiologies.

Published in:

Genes, 2025, v. 16, n. 5, p. 537, doi. 10.3390/genes16050537

By:

Braicu, Cornelia;
Ciocan, Cristina;
Bica, Cecilia;
Zanoaga, Oana;
Pop, Laura Ancuta;
Strilciuc, Stefan;
Staicu, Adelina;
Goidescu, Iulian;
Muresan, Daniel;
Surcel, Mihai;
Berindan-Neagoe, Ioana

Publication type:

Article

Genome-Wide Identification, Evolution and Expression Analysis of the G-Protein Gene Family in Poplar (Populus alba × Populus glandulosa).

Published in:

Forests (19994907), 2025, v. 16, n. 5, p. 805, doi. 10.3390/f16050805

By:

Song, Bobo;
Liu, Qian;
Zeng, Zitong;
Gu, Yiyang;
Ye, Wenxin;
Fu, Fangfang;
Ming, Meiling

Publication type:

Article

ADAM Proteases in Cancer: Biological Roles, Therapeutic Challenges, and Emerging Opportunities.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1703, doi. 10.3390/cancers17101703

By:

Arora, Sakshi;
Scott, Andrew M.;
Janes, Peter W.

Publication type:

Article

Interleukin-6 Is a Crucial Factor in Shaping the Inflammatory Tumor Microenvironment in Ovarian Cancer and Determining Its Hot or Cold Nature with Diagnostic and Prognostic Utilities.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1691, doi. 10.3390/cancers17101691

By:

Amer, Hina;
Flanagan, Katie L.;
Kampan, Nirmala C.;
Itsiopoulos, Catherine;
Scott, Clare L.;
Kartikasari, Apriliana E. R.;
Plebanski, Magdalena

Publication type:

Article

Innate Immunity and Platelets: Unveiling Their Role in Chronic Pancreatitis and Pancreatic Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1689, doi. 10.3390/cancers17101689

By:

Blümke, Juliane;
Schameitat, Moritz;
Verma, Atul;
Limbecker, Celina;
Arlt, Elise;
Kessler, Sonja M.;
Kielstein, Heike;
Krug, Sebastian;
Bazwinsky-Wutschke, Ivonne;
Haemmerle, Monika

Publication type:

Article

High KYNU Expression Is Associated with Poor Prognosis, KEAP1 / STK11 Mutations, and Immunosuppressive Metabolism in Patient-Derived but Not Murine Lung Adenocarcinomas.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1681, doi. 10.3390/cancers17101681

By:

Cai, Ling;
Rogers, Thomas J.;
Mousavi Jafarabad, Reza;
Vu, Hieu;
Yang, Chendong;
Novaresi, Nicole;
Galán-Cobo, Ana;
Girard, Luc;
Ostrin, Edwin J.;
Fahrmann, Johannes F.;
Kim, Jiyeon;
Heymach, John V.;
O'Donnell, Kathryn A.;
Xiao, Guanghua;
Xie, Yang;
DeBerardinis, Ralph J.;
Minna, John D.

Publication type:

Article

Chondrosarcoma: Multi-Targeting Therapeutic Effects of Doxorubicin, BEZ235, and the Small Molecule Aspartyl-Asparaginyl-β-hydroxylase Inhibitor SMI1182.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1671, doi. 10.3390/cancers17101671

By:

Fife, Megan;
Tong, Ming;
Das, Bhaskar;
Rodriguez, Rene;
Chokkalingam, Parthiban;
Carlson, Rolf I.;
de la Monte, Suzanne M.

Publication type:

Article

Short Tandem Repeat (STR) Somatic Mutation in Non-Melanoma Skin Cancer (NMSC): Association with Transcriptomic Profile and Potential Implications for Therapy.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1669, doi. 10.3390/cancers17101669

By:

Kibriya, Muhammad G.;
Almazan, Armando;
Argos, Maria;
Islam, Tariqul;
Shea, Christopher R.;
Ahsan, Habibul;
Jasmine, Farzana

Publication type:

Article

Petosemtamab, a Bispecific Antibody Targeting Epidermal Growth Factor Receptor (EGFR) and Leucine-Rich G Repeat-Containing Protein-Coupled Receptor (LGR5) Designed for Broad Clinical Applications.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1665, doi. 10.3390/cancers17101665

By:

Lundberg, Ante S.;
Geuijen, Cecile A. W.;
Hill, Sally;
Lammerts van Bueren, Jeroen J.;
Fumagalli, Arianna;
de Kruif, John;
Silverman, Peter B.;
Tabernero, Josep

Publication type:

Article

CAF-Targeting Antibody–Drug Conjugates (ADCs) in Solid Cancers.

Published in:

2025

By:

Papavassiliou, Kostas A.;
Sofianidi, Amalia A.;
Papavassiliou, Athanasios G.

Publication type:

Editorial

Exosome Enveloped by Nano Lipid Particle a New Model for Signal Transducer and Activator of Transcription 3 Silencer Ribonucleic Acid Delivery System to a Glioblastoma Mice Model.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1648, doi. 10.3390/cancers17101648

By:

Monfaredan, Amir;
Şen, Sena;
Hosseininasab, Alaviyehsadat;
Taştekin, Didem;
Fazli, Ghazaleh;
Bozbey, Hamza Uğur;
Yousefi, Nasrin;
Hocaoğlu, Merve;
Öncül, Mustafa Oral;
Özen, Rıdvan Seçkin

Publication type:

Article

Growth Hormone-Releasing Hormone (GHRH) Antagonist Peptides Combined with PI3K Isoform Inhibitors Enhance Cell Death in Prostate Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1643, doi. 10.3390/cancers17101643

By:

Perez-Stable, Carlos;
de las Pozas, Alicia;
Wangpaichitr, Medhi;
Sha, Wei;
Wang, Haibo;
Cai, Renzhi;
Schally, Andrew V.

Publication type:

Article

Programmed Death-1 Ligand 1 Domain Organization, Signaling Motifs, and Interactors in Cancer Immunotherapy.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1635, doi. 10.3390/cancers17101635

By:

Escors, David;
Chocarro, Luisa;
Echaide, Miriam;
Rodriguez-Neira, Claudia;
Vilaplana, Borja;
Kochan, Grazyna

Publication type:

Article

The Basis for Targeting the Tumor Macrophage Compartment in Glioblastoma Immunotherapy.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1631, doi. 10.3390/cancers17101631

By:

Eckert, Thomas;
Walton, Chase;
Bell, Marcus;
Small, Coulter;
Rowland, Nathan C.;
Rivers, Charlotte;
Zukas, Alicia;
Lindhorst, Scott;
Fecci, Peter;
Strickland, Ben A.

Publication type:

Article

TP53 Mutation-Specific Dysregulation of Store-Operated Calcium Entry and Apoptotic Sensitivity in Triple-Negative Breast Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1614, doi. 10.3390/cancers17101614

By:

Rabab, Kaneez E.;
Buchanan, Paul J.;
Colley, Grace;
White, Anita;
Murphy, Aisling;
McCormack, Chloe;
Eustace, Alex J.

Publication type:

Article

PI3Kδ as a Novel Therapeutic Target for Aggressive Prostate Cancer.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1610, doi. 10.3390/cancers17101610

By:

Wang, Bi-Dar;
Lucero, Alyssa;
Ha, Siyoung;
Yarmohammadi, Reyhaneh

Publication type:

Article

Single-Agent and Associated Therapies with Monoclonal Antibodies: What About Follicular Lymphoma?

Published in:

Cancers, 2025, v. 17, n. 10, p. 1602, doi. 10.3390/cancers17101602

By:

Cancemi, Gabriella;
Campo, Chiara;
Caserta, Santino;
Rizzotti, Iolanda;
Mannina, Donato

Publication type:

Article

The Role of the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma: Recent Advancements and Emerging Therapeutic Strategies.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1599, doi. 10.3390/cancers17101599

By:

Glapiński, Franciszek;
Zając, Weronika;
Fudalej, Marta;
Deptała, Andrzej;
Czerw, Aleksandra;
Sygit, Katarzyna;
Kozłowski, Remigiusz;
Badowska-Kozakiewicz, Anna

Publication type:

Article

Fish Oil Supplementation Attenuates Offspring's Neurodevelopmental Changes Induced by a Maternal High-Fat Diet in a Rat Model.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1741, doi. 10.3390/nu17101741

By:

Muñoz, Yasna;
Kaune, Heidy;
Dagnino-Subiabre, Alexies;
Cruz, Gonzalo;
Toledo, Jorge;
Valenzuela, Rodrigo;
Moraga, Renato;
Tabilo, Luis;
Flores, Cristian;
Muñoz, Alfredo;
Crisosto, Nicolás;
Montiel, Juan F.;
Maliqueo, Manuel

Publication type:

Article

The Protective Effects of Pectic Polysaccharides on Dextran Sulfate Sodium-Induced Colitis in Drosophila melanogaster and Their Structure–Function Relationships.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1738, doi. 10.3390/nu17101738

By:

Sun, Zhenou;
Qi, Tianyu;
Cheng, Boyu;
Guo, Yingxiao;
Atehli, Dima;
Cui, Steve W.;
Kang, Ji;
Guo, Qingbin

Publication type:

Article

Sweet Taste Receptors' Genetic Variability in Advanced Potential Targets of Obesity.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1712, doi. 10.3390/nu17101712

By:

Wagner-Reguero, Sonia;
Fernández, Lara P.;
Colmenarejo, Gonzalo;
Cruz-Gil, Silvia;
Espinosa, Isabel;
Molina, Susana;
Crespo, María Carmen;
Aguilar-Aguilar, Elena;
Marcos-Pasero, Helena;
de la Iglesia, Rocío;
Loria-Kohen, Viviana;
Ruiz, Ricardo Ramos;
Laparra-Llopis, Moisés;
de Molina, Ana Ramírez;
Gómez de Cedrón, Marta

Publication type:

Article

Impaired Mitophagy Contributes to Pyroptosis in Sarcopenic Obesity Zebrafish Skeletal Muscle.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1711, doi. 10.3390/nu17101711

By:

Tang, Xiangbin;
Zou, Yunyi;
Yang, Siyuan;
Chen, Zhanglin;
Zhou, Zuoqiong;
Peng, Xiyang;
Tang, Changfa

Publication type:

Article

Glutamine Administration Attenuates Poly(I:C)-Induced Lung Injury by Reducing Neutrophil Infiltration and Activating the TLR-3 Antiviral Pathway.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1700, doi. 10.3390/nu17101700

By:

Su, Li-Han;
Tsai, Wen-Chiuan;
Shirakawa, Hitoshi;
Tsai, Yu-Ling;
Yeh, Sung-Ling;
Yeh, Chiu-Li

Publication type:

Article

A Novel Camel Milk-Derived Peptide LLPK Improves Glucose-Lipid Metabolism in db / db Mice via PPAR Signaling Pathway.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1693, doi. 10.3390/nu17101693

By:

Han, Binsong;
Ye, Yuhui;
Zhang, Cunzheng;
Zhang, Lina;
Zhou, Peng

Publication type:

Article

3,3′-Diindolylmethane Ameliorates Metabolism Dysfunction-Associated Fatty Liver Disease via AhR/p38 MAPK Signaling.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1681, doi. 10.3390/nu17101681

By:

Su, Jiewen;
Fang, Heng;
Lin, Yunfeng;
Yao, Yilu;
Liu, Yanxi;
Zhong, Yuquan;
Li, Xudong;
Sun, Siyu;
Huang, Bing;
Yang, Guangyu;
Li, Wenxue;
Zhang, Yan;
Li, Juntao;
Wu, Jinyin;
Liu, Weiwen;
Hu, Qiansheng;
Zhu, Wei

Publication type:

Article

Coix Seed Oil Alleviates Hyperuricemia in Mice by Ameliorating Oxidative Stress and Intestinal Microbial Composition.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1679, doi. 10.3390/nu17101679

By:

Wu, Guozhen;
Wang, Xinming;
Dong, Hongjing;
Yu, Jinqian;
Li, Tao;
Wang, Xiao

Publication type:

Article