Currently, gastrointestinal diseases are included among the main infectious diseases of pigs, both because of their frequency of appearance and because of the economic cost they represent for pig farmers. In recent years, the emergence and re-emergence of different enteric viruses, combined with the absence of commercial vaccines for the prevention of these viral enteric infections in pigs, has made it difficult to control enteric processes, increasing the impact of viral enteritis in pig farms. Porcine Enteric Diarrhea (PED) produces a clinical condition characterized by the rapid onset of diarrhea, which is accompanied by vomiting and dehydration, and can cause high lethality in the first days of life of piglets, as well as growth retardation in older pigs. PED is caused by a single-chain alpha-coronavirus that replicates in enterocytes, lysing and necrotising them, leading to the appearance of clinical signs within the first 10 days after infection. Molecular diagnosis of PED virus is considered the best option as it is highly sensitive and specific as it detects early infection and excretion of the virus during the period between infection and seroconversion compared to immunological techniques.