Works matching DE "REDUCTASE inhibitors"

Results: 676

Clinical Predictors and Risk Factors of Gleason Score Upgrade: A Retrospective Cohort Analysis.

Published in:

Diagnostics (2075-4418), 2025, v. 15, n. 10, p. 1238, doi. 10.3390/diagnostics15101238

By:

Sciorio, Carmine;
Giannella, Riccardo;
Romano, Lorenzo;
Mirto, Benito Fabio;
Di Girolamo, Antonio;
Ruffo, Antonio;
Romeo, Giuseppe;
Esposito, Fabio;
Crocetto, Felice;
Napolitano, Luigi;
Balsamo, Raffaele;
Trama, Francesco;
Bottone, Francesco;
Quattrone, Carmelo;
Imperatore, Vittorio;
Spirito, Lorenzo

Publication type:

Article

Benign prostatic enlargement and lower urinary tract symptoms: An update on treatment.

Published in:

Medicine Today, 2025, v. 26, n. 5, p. 12

By:

SOARES, DEANNE S.

Publication type:

Article

Ferroptosis‐modulating small molecules for targeting drug‐resistant cancer: Challenges and opportunities in manipulating redox signaling.

Published in:

Medicinal Research Reviews, 2023, v. 43, n. 3, p. 614, doi. 10.1002/med.21933

By:

Koeberle, Solveigh C.;
Kipp, Anna P.;
Stuppner, Hermann;
Koeberle, Andreas

Publication type:

Article

Statins affect human iPSC-derived cardiomyocytes by interfering with mitochondrial function and intracellular acidification.

Published in:

Basic Research in Cardiology, 2024, v. 119, n. 2, p. 309, doi. 10.1007/s00395-023-01025-x

By:

Somers, Tim;
Siddiqi, Sailay;
Maas, Renee G. C.;
Sluijter, Joost P. G.;
Buikema, Jan W.;
van den Broek, Petra H. H.;
Meuwissen, Tanne J.;
Morshuis, Wim J.;
Russel, Frans G. M.;
Schirris, Tom J. J.

Publication type:

Article

Syntheses of some α-cyclic tripeptides as potential inhibitors for HMG-CoA Reductase.

Published in:

Amino Acids, 2015, v. 47, n. 8, p. 1495, doi. 10.1007/s00726-015-1977-2

By:

Chakraborty, Subrata;
Lin, Shih-Hung;
Shiuan, David;
Tai, Dar-Fu

Publication type:

Article

Mitigating neuroinflammation in cognitive areas: exploring the impact of HMG-CoA reductase inhibitor.

Published in:

Biochemical Journal, 2024, v. 481, n. 22, p. 1585, doi. 10.1042/BCJ20240217

By:

Rocha Catalão, Carlos Henrique;
Angenendt da Costa, Luis Henrique;
Rodrigo dos Santos, Jonathas;
Carla Alberici, Luciane;
Luciano Falconi-Sobrinho, Luiz;
Cysne Coimbra, Norberto;
Dominguini, Diogo;
Dal-Pizzol, Felipe;
Barichello, Tatiana;
Alves Rocha, Maria José

Publication type:

Article

Synergistic Effect of Lovastatin and Selegiline on the Differentiation of Bone Marrow Stromal Cells Into Neuron-Like Cells.

Published in:

Jentashapir Journal of Cellular & Molecular Biology, 2023, v. 14, n. 4, p. 1, doi. 10.5812/jjcmb-141092

By:

Abdanipour, Alireza;
Karami, Behnam;
Fridoni, Mohammad Javad;
Mohamadi, Momeneh;
Fakheri, Farzaneh

Publication type:

Article

MODELING OF NEW POTENTIAL INHIBITORS OF DIHYDROFOLATE REDUCTASE BASED ON 1,3,4-TH I AD I AZ OLE AMIDOALKYL DERIVATIVES.

Published in:

Issues of Chemistry & Chemical Technology / Voprosy Khimii & Khimicheskoi Tekhnologii, 2023, n. 5, p. 91, doi. 10.32434/0321-4095-2023-150-5-91-97

By:

Pavlova, V. V.;
Zadorotftnii, P. V.;
Kiselev, V. V.;
Kharchenko, A. V.;
Okhtina, O. V.

Publication type:

Article

Simvastatin: In Vitro Metabolic Profiling of a Potent Competitive HMG-CoA Reductase Inhibitor.

Published in:

Separations (2297-8739), 2022, v. 9, n. 12, p. 400, doi. 10.3390/separations9120400

By:

Yin, Wencui;
Alwabli, Reem I.;
Attwa, Mohamed W.;
Rahman, A. F. M. Motiur;
Kadi, Adnan A.

Publication type:

Article

TAS1553, a small molecule subunit interaction inhibitor of ribonucleotide reductase, exhibits antitumor activity by causing DNA replication stress.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03516-4

By:

Ueno, Hiroyuki;
Hoshino, Takuya;
Yano, Wakako;
Tsukioka, Sayaka;
Suzuki, Takamasa;
Hara, Shoki;
Ogino, Yoshio;
Chong, Khoon Tee;
Suzuki, Tatsuya;
Tsuji, Shingo;
Itadani, Hikaru;
Yamamiya, Ikuo;
Otsu, Yoshihiro;
Ito, Satoshi;
Yonekura, Toshiya;
Terasaka, Miki;
Tanaka, Nozomu;
Miyahara, Seiji

Publication type:

Article

Cardiovascular Safety and Possible Benefit of a 5-Alpha Reductase Inhibitor among Benign Prostatic Hyperplasia Patients, A Nationally Representative Cohort of Korean Men.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 5, p. 733, doi. 10.3390/jcm8050733

By:

Chang, Jooyoung;
Choi, Seulggie;
Kim, Kyuwoong;
Park, Sang Min

Publication type:

Article

Impact of Oxidative Stress and Protein S-Glutathionylation in Aortic Valve Sclerosis Patients with Overt Atherosclerosis.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 4, p. 552, doi. 10.3390/jcm8040552

By:

Valerio, Vincenza;
Myasoedova, Veronika A.;
Moschetta, Donato;
Porro, Benedetta;
Perrucci, Gianluca L.;
Cavalca, Viviana;
Cavallotti, Laura;
Songia, Paola;
Poggio, Paolo

Publication type:

Article

In Silico Study Probes Potential Inhibitors of Human Dihydrofolate Reductase for Cancer Therapeutics.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 2, p. 233, doi. 10.3390/jcm8020233

By:

Rana, Rabia Mukhtar;
Rampogu, Shailima;
Zeb, Amir;
Son, Minky;
Park, Chanin;
Lee, Gihwan;
Yoon, Sanghwa;
Baek, Ayoung;
Parameswaran, Sarvanan;
Park, Seok Ju;
Lee, Keun Woo

Publication type:

Article

Long-Term Statin Administration Does Not Affect Warfarin Time in Therapeutic Range in Australia or Singapore.

Published in:

Journal of Clinical Medicine, 2018, v. 7, n. 5, p. 97, doi. 10.3390/jcm7050097

By:

Bernaitis, Nijole;
Ching, Chi Keong;
Teo, Siew Chong;
Badrick, Tony;
Davey, Andrew K.;
Crilly, Julia;
Anoopkumar-Dukie, Shailendra

Publication type:

Article

The Effect of Rosuvastatin on the Liver Enzyme of NMRI Mouse.

Published in:

Novelty in Biomedicine, 2022, v. 10, n. 2, p. 101

By:

Asl, Atena Nehzati;
Rasooli, Azadeh;
Fazeli, Maryam;
Saffarpour, Mehranoush

Publication type:

Article

Separation and Identification of Antioxidants and Aldose Reductase Inhibitors in Lepechinia meyenii (Walp.) Epling.

Published in:

Plants (2223-7747), 2021, v. 10, n. 12, p. 2773, doi. 10.3390/plants10122773

By:

Zuo, Guanglei;
Je, Kang-Hoon;
Guillen Quispe, Yanymee N.;
Shin, Kyong-Oh;
Kim, Hyun Yong;
Kim, Kang Hyuk;
Arce, Paul H. Gonzales;
Lim, Soon Sung

Publication type:

Article

The Renoprotective Effect of Atorvastatin in a Rat Model of High-Fat High-Fructose Diet-Induced Renal Injury.

Published in:

Egyptian Academic Journal of Biological Sciences. D, Histology & Histochemistry, 2024, v. 16, n. 1, p. 179, doi. 10.21608/EAJBSD.2024.360842

By:

Eldesoqui, Mamdouh;
Mohamed, Abdelaty S.;
Nasr1-, Ahmed N. A.;
Ali, Sahar K.;
Eldaly, Mai M.;
Embaby, Eman M.;
Ahmed, Heba S.;
Saeed, Zeinab M.;
Mohammed, Zeinab A.;
Soliman, Rania H. M.

Publication type:

Article

Selective estrogen receptor modulators for BPH: new factors on the ground.

Published in:

Prostate Cancer & Prostatic Diseases, 2013, v. 16, n. 3, p. 226, doi. 10.1038/pcan.2013.17

By:

Garg, M;
Dalela, D;
Goel, A;
Kumar, M;
Gupta, G;
Sankhwar, S N

Publication type:

Article

The incidence of acute urinary retention secondary to BPH is increasing among California men.

Published in:

Prostate Cancer & Prostatic Diseases, 2013, v. 16, n. 3, p. 260, doi. 10.1038/pcan.2013.11

By:

Groves, H K;
Chang, D;
Palazzi, K;
Cohen, S;
Parsons, J K

Publication type:

Article

Antidiabetic Potential of Marine Brown Algae—a Mini Review.

Published in:

Journal of Diabetes Research, 2020, p. 1, doi. 10.1155/2020/1230218

By:

Gunathilaka, Thilina L.;
Samarakoon, Kalpa;
Ranasinghe, Pathmasiri;
Peiris, L. Dinithi C.

Publication type:

Article

Atorvastatin potentiates the chemosensitivity of human liver cancer cells to cisplatin via downregulating YAP1.

Published in:

Oncology Letters, 2021, v. 21, n. 2, p. 1, doi. 10.3892/ol.2020.12343

By:

LIWEN GUO;
JIAPING ZHENG;
HUI ZENG;
ZHEWEI ZHANG;
GUOLIANG SHAO

Publication type:

Article

Steroid 5 alpha-reductase 2 enzyme variants, biomass exposure and tobacco use in Mexican patients with prostate cancer.

Published in:

Oncology Letters, 2020, v. 20, n. 5, p. 1, doi. 10.3892/ol.2020.12124

By:

ROLANDO DELGADO-BALDERAS, JESUS;
LEONID GALLARDO-BLANCO, HUGO;
YEE-DE LEÓN, JUAN FELIPE;
RIVAS-ESTILLA, ANA MARIA;
SOTO-GARCÍA, BRENDA;
ARÁIZ-HERNÁNDEZ, DIANA;
GARZA-GUAJARDO, RAQUEL;
NÁÑEZ-MARÍN, MELISSA;
HERNÁNDEZ-BARAJAS, DAVID;
MISSAEL GARCÍA-BAILÓN, ALDO;
VÍZCARRA-MATA, GUILLERMO;
ALBERTO OCAÑA-MUNGUÍA, MARCO;
SALVADOR GÓMEZ-GUERRA, LAURO;
NOHEMÍ SÁNCHEZ-DOMÍNGUEZ, CELIA

Publication type:

Article

Overexpression of carbonyl reductase 1 inhibits malignant behaviors and epithelial mesenchymal transition by suppressing TGF-β signaling in uterine leiomyosarcoma cells.

Published in:

Oncology Letters, 2019, v. 18, n. 2, p. 1503, doi. 10.3892/ol.2019.10429

By:

Kajimura, Takuya;
Sato, Shun;
Murakami, Akihiro;
Hayashi-Okada, Maki;
Nakashima, Kengo;
Sueoka, Kotaro;
Sugino, Norihiro

Publication type:

Article

Low-density lipoprotein receptor expression is involved in the beneficial effect of photodynamic therapy using talaporfin sodium on gastric cancer cells.

Published in:

Oncology Letters, 2019, v. 17, n. 3, p. 3261

By:

Kanda, Tsutomu;
Sugihara, Takaaki;
Takata, Tomoaki;
Mae, Yukari;
Kinoshita, Hidehito;
Sakaguchi, Takuki;
Hasegawa, Takashi;
Kurumi, Hiroki;
Ikebuchi, Yuichiro;
Murakami, Takashi;
Isomoto, Hajime

Publication type:

Article

Simvastatin potentiates doxorubicin activity against MCF-7 breast cancer cells.

Published in:

Oncology Letters, 2017, v. 14, n. 5, p. 6243, doi. 10.3892/ol.2017.6783

By:

BURANRAT, BENJAPORN;
SUWANNALOET, WANWISA;
NAOWABOOT, JARINYAPORN

Publication type:

Article

A tale of two trials: The impact of 5α-reductase inhibition on prostate cancer (Review).

Published in:

Oncology Letters, 2014, v. 8, n. 4, p. 1391, doi. 10.3892/ol.2014.2388

By:

LACY, JOHN M.;
KYPRIANOU, NATASHA

Publication type:

Article

NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies.

Published in:

Clinical Hemorheology & Microcirculation, 2019, v. 73, n. 1, p. 249, doi. 10.3233/CH-199226

By:

Schulz, Christian;
Kammerer, Sarah;
Küpper, Jan-Heiner;
Wiggermann, P.;
Krüger-Genge, A.;
Jung, F.

Publication type:

Article

Treatment with finasteride and prostate cancer survival.

Published in:

Scandinavian Journal of Urology (Taylor & Francis Ltd), 2013, v. 47, n. 4, p. 265, doi. 10.3109/00365599.2012.737366

By:

Kjellman, Anders;
Friis, Søren;
Granath, Fredrik;
Gustafsson, Ove;
Sørensen, Henrik Toft;
Akre, Olof

Publication type:

Article

5‐Alpha reductase inhibitor related litigation: A legal database review.

Published in:

Andrology, 2022, v. 10, n. 3, p. 470, doi. 10.1111/andr.13145

By:

Low, Patrick;
Li, Kevin D.;
Hakam, Nizar;
Bell, Alexander;
Abbasi, Behzad;
Lui, Jason;
Shaw, Nathan M.;
Breyer, Benjamin N.

Publication type:

Article

Oncostatin M stimulates immature Leydig cell proliferation but inhibits its maturation and function in rats through JAK1/STAT3 signaling and induction of oxidative stress in vitro.

Published in:

Andrology, 2022, v. 10, n. 2, p. 354, doi. 10.1111/andr.13109

By:

Tian, Lili;
Li, Xueyun;
Wang, Yiyan;
Chen, Quanxu;
Li, Xiaoheng;
Ge, Ren‐Shan;
Li, Xingwang

Publication type:

Article

Is there a role for 5α‐reductase inhibitors in transgender individuals?

Published in:: Andrology, 2021, v. 9, n. 6, p. 1729, doi. 10.1111/andr.12881
Publication type:: Article

Phenothiazine‐based virtual screening, molecular docking, and molecular dynamics of new trypanothione reductase inhibitors of Trypanosoma cruzi.

Published in:

Molecular Informatics, 2023, v. 42, n. 10, p. 1, doi. 10.1002/minf.202300069

By:

González‐González, Alonzo;
Vázquez, Citlali;
Encalada, Rusely;
Saavedra, Emma;
Vázquez‐Jiménez, Lenci K.;
Ortiz‐Pérez, Eyra;
Bolognesi, María Laura;
Rivera, Gildardo

Publication type:

Article

Investigation of the Potential of Bile Acid Methyl Esters as Inhibitors of Aldo‐keto Reductase 1C2: Insight from Molecular Docking, Virtual Screening, Experimental Assays and Molecular Dynamics.

Published in:

Molecular Informatics, 2022, v. 41, n. 10, p. 1, doi. 10.1002/minf.202100256

By:

Marinović, Maja A.;
Petri, Edward T.;
Grbović, Ljubica M.;
Vasiljević, Bojana R.;
Jovanović‐Šanta, Suzana S.;
Bekić, Sofija S.;
Ćelić, Andjelka S.

Publication type:

Article

Two‐ and Three‐dimensional Quantitative Structure‐activity Relationship Models Based on Conformer Structures.

Published in:

Molecular Informatics, 2021, v. 40, n. 3, p. 1, doi. 10.1002/minf.202000123

By:

Nitta, Fumika;
Kaneko, Hiromasa

Publication type:

Article

Quinoxalinones Based Aldose Reductase Inhibitors: 2D and 3D-QSAR Analysis.

Published in:

Molecular Informatics, 2019, v. 38, n. 8/9, p. 1, doi. 10.1002/minf.201800149

By:

Masand, Vijay H.;
Elsayed, Nahed N.;
Thakur, Sumersingh D.;
Gawhale, Nandkishor;
Rathore, Mithilesh M.

Publication type:

Article

Pharmacogenetics in the Treatment of Cardiovascular Diseases and Its Current Progress Regarding Implementation in the Clinical Routine.

Published in:

Genes, 2019, v. 10, n. 4, p. 261, doi. 10.3390/genes10040261

By:

Dávila-Fajardo, Cristina Lucía;
Díaz-Villamarín, Xando;
Antúnez-Rodríguez, Alba;
Fernández-Gómez, Ana Estefanía;
García-Navas, Paloma;
Martínez-González, Luis Javier;
Dávila-Fajardo, José Augusto;
Cabeza Barrera, José

Publication type:

Article

Regulatory Effect on Skin Differentiation by Mevastatin in Psoriasis Model Using TNF-α and IL-17 Induced HaCaT Cells.

Published in:

Biotechnology & Bioprocess Engineering, 2021, v. 26, n. 3, p. 348, doi. 10.1007/s12257-020-0368-z

By:

Kim, Min Young;
Choi, You Won;
Hwang, Hyung Seo

Publication type:

Article

A Novel Biological Activity of the STAT3 Inhibitor Stattic in Inhibiting Glutathione Reductase and Suppressing the Tumorigenicity of Human Cervical Cancer Cells via a ROS-Dependent Pathway.

Published in:

OncoTargets & Therapy, 2021, v. 14, p. 4047, doi. 10.2147/OTT.S313507

By:

Xia, Yuchen;
Wang, Guihua;
Jiang, Manli;
Liu, Xueting;
Zhao, Yan;
Song, Yinghui;
Jiang, Binyuan;
Zhu, Demao;
Hu, Ling;
Zhang, Zhao;
Cao, Ting;
Wang, Ji Ming;
Hu, Jinyue

Publication type:

Article

Comparative Study of Lipophilic Statin Activity in 2D and 3D in vitro Models of Human Breast Cancer Cell Lines MDA-MB-231 and MCF-7.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 13201, doi. 10.2147/OTT.S283033

By:

Bytautaite, Meda;
Petrikaite, Vilma

Publication type:

Article

Simvastatin Inhibits the Malignant Behaviors of Gastric Cancer Cells by Simultaneously Suppressing YAP and β-Catenin Signaling.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 2057, doi. 10.2147/OTT.S237693

By:

Liu, Qing;
Xia, Hongwei;
Zhou, Sheng;
Tang, Qiulin;
Zhou, Jitao;
Ren, Min;
Bi, Feng

Publication type:

Article

Docking-Based Virtual Screening and Molecular Dynamics Simulations of Quercetin Analogs as Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors of Mycobacterium tuberculosis.

Published in:

Scientia Pharmaceutica, 2021, v. 89, n. 2, p. 1, doi. 10.3390/scipharm89020020

By:

Pitaloka, Dian Ayu Eka;
Ramadhan, Dwi Syah Fitra;
Arfan;
Chaidir, Lidya;
Fakih, Taufik Muhammad

Publication type:

Article

Influence of statins in metastatic castration-resistant prostate cancer patients treated with new antiandrogen therapies: a systematic review and meta-analysis.

Published in:

Einstein (16794508), 2022, v. 20, p. 1, doi. 10.31744/einstein_journal/2022RW6339

By:

Mariano Jr, Renato;
Tavares, Kevin Lima;
Panhoca, Renato;
Sadi, Marcus

Publication type:

Article

Lipid profile and statin use in critical care setting: implications for kidney outcome.

Published in:

Einstein (16794508), 2019, v. 17, n. 3, p. 1, doi. 10.31744/einstein_journal/2019AO4399

By:

Malbouisson, Isabelle;
Quinto, Beata Marie;
de Souza Durão Junior, Marcelino;
Martins Monte, Júlio Cesar;
Pavão dos Santos, Oscar Fernando;
Camargo Narciso, Roberto;
Aparecida Dalboni, Maria;
Costa Batista, Marcelo

Publication type:

Article

Association Between 5-Alpha Reductase Inhibitor Use and The Risk of Depression: A Meta-Analysis.

Published in:

Urology Journal, 2021, v. 18, n. 2, p. 1

By:

Tuo Deng;
Xiaolu Duan;
Zihao He;
Zhijian Zhao;
Guohua Zeng

Publication type:

Article

The Effects of Oral 5-alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in Rat Model.

Published in:

Urology Journal, 2019, v. 16, n. 2, p. 205

By:

Kilic, Sahin;
Kolukcu, Engin;
Erdemir, Fikret;
Benli, Ismail;
Arici, Akgul

Publication type:

Article

Does Preoperative Use of Dutasteride Decrease Bleeding During Open Prostatectomy?

Published in:

Urology Journal, 2018, v. 15, n. 1, p. 6022

By:

Demirbas, Arif;
Resorlu, Berkan;
Tolga Gulpinar, Murat;
Kardas, Sina;
Gokhan Doluoglu, Omer;
Tepeler, Abdulkadir;
Kilinc, Muhammet Fatih;
Karakan, Tolga;
Ozcan, Serkan

Publication type:

Article

Hormonal Therapy and Radiation Therapy in Prostate Cancer: 5-Year Outcomes From a Trial Evaluating Combined Androgen Blockade With 5-Alpha Reductase Inhibitors as an Alternative to Gonadotropin Releasing Hormone Agonists.

Published in:

Clinical Genitourinary Cancer, 2024, v. 22, n. 4, p. N.PAG, doi. 10.1016/j.clgc.2024.102103

By:

Rajeev-Kumar, Greeshma;
Pitroda, Sean P.;
Szmulewitz, Russell Z.;
Skolarus, Ted;
Eggener, Scott E.;
Liauw, Stanley L.

Publication type:

Article

The Use of 5-Alpha Reductase Inhibitors and Alpha-1 Blockers Does Not Improve Clinical Outcome in Male Patients Undergoing Radical Cystectomy for Bladder Cancer in Quebec, Canada.

Published in:

Clinical Genitourinary Cancer, 2021, v. 19, n. 4, p. e1, doi. 10.1016/j.clgc.2021.01.007

By:

Wissing, Michel D.;
O'Flaherty, Ana;
Dragomir, Alice;
Tanguay, Simon;
Kassouf, Wassim;
Aprikian, Armen G.

Publication type:

Article

Effects of Topical Atorvastatin (2 %) on Posthemorrhoidectomy Pain and Wound Healing: A Randomized Double-Blind Placebo-Controlled Clinical Trial.

Published in:

World Journal of Surgery, 2017, v. 41, n. 2, p. 596, doi. 10.1007/s00268-016-3749-x

By:

Ala, Shahram;
Alvandipour, Mina;
Saeedi, Majid;
Hamidian, Maliheh;
Shiva, Afshin;
Rahmani, Nasrin;
Faramarzi, Fatemeh

Publication type:

Article

Geographic Variation in HMG-CoA Reductase Inhibitor Use in Dialysis Patients.

Published in:

JGIM: Journal of General Internal Medicine, 2012, v. 27, n. 11, p. 1475, doi. 10.1007/s11606-012-2112-7

By:

Wetmore, James;
Mahnken, Jonathan;
Mukhopadhyay, Purna;
Hou, Qingjiang;
Ellerbeck, Edward;
Rigler, Sally;
Spertus, John;
Shireman, Theresa

Publication type:

Article