An Infant with a Diagnostically Challenging Hepatic Teratoma, Hypofibrinogenemia, and Adrenal Neuroblastoma: Case Report.

FRIED, IRIS; ROM-GROSS, EITAN; FINEGOLD, MILTON; SIMANOVSKY, NATALIA; REVEL-VILK, SHOSHANA; BEN-NERIAH, ZIVA; WEINTRAUB, MICHAEL; PAPPO, ORIT; MEIR, KAREN

Teratomas of the liver are exceedingly rare. Neuroblastoma is the most common, extracranial solid tumor of infancy. We describe the case of a 2-month-old, female infant who presented with an abdominal mass arising in the right lobe of the liver, and a severe coagulopathy, which necessitated cryoprecipitate infusion. Biopsy was interpreted as hepatoblastoma. Following resection, difficulty classifying the mass led to several consultations, and an eventual diagnosis of teratoma. During follow-up, the patient was diagnosed with right adrenal neuroblastoma, which, in retrospect, had been present before the hepatic resection. To our knowledge, these 2 tumors have never been reported together, or in combination with isolated hypofibrinogenemia.

NEUROBLASTOMA; BLOOD coagulation disorders; TERATOMA; TUMORS; TERATOCARCINOMA

Pediatric & Developmental Pathology, 2015, Vol 18, Issue 3, p251

1093-5266

Academic Journal

10.2350/13-08-1361-CR.1