The article discusses a case report of a 77-year-old woman with atopic dermatitis and asthma who developed hypereosinophilia while being treated with dupilumab. The patient's condition improved after switching to tralokinumab, which targets interleukin-13. Tralokinumab was found to be effective in controlling the symptoms of atopic dermatitis and asthma without causing hypereosinophilia. The study highlights the potential of tralokinumab as an alternative treatment for patients with atopic dermatitis and asthma who develop hypereosinophilia.