Works matching AU Neel, Benjamin G.
Results: 72
Corrigendum: Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling.
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- Nature, 2014, v. 508, n. 7496, p. 420, doi. 10.1038/nature13170
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- Article
Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling.
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- Nature, 2013, v. 499, n. 7459, p. 491, doi. 10.1038/nature12396
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- Article
CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity.
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- Nature Immunology, 2004, v. 5, n. 6, p. 651, doi. 10.1038/ni1072
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- Article
PTP1B regulates Eph receptor function and trafficking.
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- Journal of Cell Biology, 2010, v. 191, n. 6, p. 1189, doi. 10.1083/jcb.201005035
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- Article
SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth.
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- Journal of Cell Biology, 2006, v. 175, n. 1, p. 87, doi. 10.1083/jcb.200602029
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- Article
Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner.
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- Science Signaling, 2018, v. 11, n. 522, p. 1, doi. 10.1126/scisignal.aao1591
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- Article
Targeting uroporphyrinogen decarboxylase for head and neck cancer treatment.
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- BMC Proceedings, 2013, v. 7, n. Suppl 2, p. 1, doi. 10.1186/1753-6561-7-S2-P19
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- Article
Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.
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- 2011
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- journal article
MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutation.
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- 2011
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- journal article
Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation.
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- 2010
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- journal article
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis.
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- Nature, 1981, v. 290, n. 5806, p. 475, doi. 10.1038/290475a0
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- Article
Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47440-w
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- Article
The Noonan Syndrome-linked Raf1<sup>L613V</sup> mutation drives increased glial number in the mouse cortex and enhanced learning.
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- PLoS Genetics, 2019, v. 15, n. 4, p. 1, doi. 10.1371/journal.pgen.1008108
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- Article
Integrated analysis of proteome, phosphotyrosine-proteome, tyrosine-kinome, and tyrosine-phosphatome in acute myeloid leukemia.
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- Proteomics, 2017, v. 17, n. 6, p. n/a, doi. 10.1002/pmic.201600361
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- Article
Differential regulation of FGFR3 by PTPN1 and PTPN2.
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- Proteomics, 2015, v. 15, n. 2/3, p. 419, doi. 10.1002/pmic.201400259
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- Article
MMD-associated RNF213 SNPs encode dominant-negative alleles that globally impair ubiquitylation.
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- Life Science Alliance, 2022, v. 5, n. 5, p. 1, doi. 10.26508/lsa.202000807
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- Article
Uroporphyrinogen Decarboxylase Is a Radiosensitizing Target for Head and Neck Cancer.
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- Science Translational Medicine, 2011, v. 3, n. 67, p. 1, doi. 10.1126/scitranslmed.3001922
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- Article
Methods to monitor classical protein-tyrosine phosphatase oxidation.
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- FEBS Journal, 2013, v. 280, n. 2, p. 459, doi. 10.1111/j.1742-4658.2012.08626.x
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- Article
Increased BRAF Heterodimerization Is the Common Pathogenic Mechanism for Noonan Syndrome-Associated RAF1 Mutants.
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- Molecular & Cellular Biology, 2012, v. 32, n. 19, p. 3872, doi. 10.1128/MCB.00751-12
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- Article
Neuronal Protein Tyrosine Phosphatase 1B Deficiency Results in Inhibition of Hypothalamic AMPK and Isoform-Specific Activation of AMPK in Peripheral Tissues.
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- Molecular & Cellular Biology, 2009, v. 29, n. 16, p. 4563, doi. 10.1128/MCB.01914-08
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- Article
Improved Glucose Homeostasis in Mice with Muscle-Specific Deletion of Protein-Tyrosine Phosphatase 1B.
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- Molecular & Cellular Biology, 2007, v. 27, n. 21, p. 34, doi. 10.1128/MCB.00959-07
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- Article
Phosphatidylinositol 3-Kinase p85α Subunit-Dependent Interaction with BCR/ABL-Related Fusion Tyrosine Kinases: Molecular Mechanisms and Biological Consequences.
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- Molecular & Cellular Biology, 2005, v. 25, n. 18, p. 8001, doi. 10.1128/MCB.25.18.8001-8008.2005
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- Article
Coordinated Regulation of Insulin Signaling by the Protein Tyrosine Phosphatases PTP1B and TCPTP.
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- Molecular & Cellular Biology, 2005, v. 25, n. 2, p. 819, doi. 10.1128/MCB.25.2.819-829.2005
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- Article
Site-Selective Regulation of Platelet-Derived Growth Factor β Receptor Tyrosine Phosphorylation by T-Cell Protein Tyrosine Phosphatase.
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- Molecular & Cellular Biology, 2004, v. 24, n. 5, p. 2190, doi. 10.1128/MCB.24.5.2190-2201.2004
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- Article
Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00503-w
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- Article
Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome.
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- Nature Communications, 2017, v. 8, n. 5, p. 15518, doi. 10.1038/ncomms15518
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- Article
Antagonism between binding site affinity and conformational dynamics tunes alternative cis-interactions within Shp2.
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- Nature Communications, 2013, v. 4, n. 6, p. 2037, doi. 10.1038/ncomms3037
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- Article
Signal transfer in human protein tyrosine phosphatase PTP1B from allosteric inhibitor P00058.
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- Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 24, p. 13823, doi. 10.1080/07391102.2021.1994879
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- Article
Addendum: Neuronal PTP1B regulates body weight, adiposity and leptin action.
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- 2010
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- Correction Notice
Corrigendum: Neuronal PTP1B regulates body weight, adiposity and leptin action.
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- 2010
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- Correction Notice
Neuronal PTP1B regulates body weight, adiposity and leptin action.
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- Nature Medicine, 2006, v. 12, n. 8, p. 917, doi. 10.1038/nm1435
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- Article
Stops along the RAS pathway in human genetic disease.
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- Nature Medicine, 2006, v. 12, n. 3, p. 283, doi. 10.1038/nm0306-283
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- Article
A role for the scaffolding adapter GAB2 in breast cancer.
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- Nature Medicine, 2006, v. 12, n. 1, p. 114, doi. 10.1038/nm1341
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- Article
PTP-1B is an essential positive regulator of platelet integrin signaling.
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- Journal of Cell Biology, 2005, v. 170, n. 5, p. 837, doi. 10.1083/jcb.200503125
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- Article
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase.
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- Journal of Cell Biology, 2003, v. 163, n. 5, p. 999, doi. 10.1083/jcb.200309036
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- Article
Critical role for scaffolding adapter Gab2 in FcγR-mediated phagocytosis.
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- Journal of Cell Biology, 2003, v. 161, n. 6, p. 1151, doi. 10.1083/jcb.200212158
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- Article
Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (PTPN11).
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- BMC Structural Biology, 2014, v. 14, p. 1, doi. 10.1186/1472-6807-14-10
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- Article
Ventromedial hypothalamus-specific Ptpn1 deletion exacerbates diet-induced obesity in female mice.
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- Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3781, doi. 10.1172/JCI68585
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- Article
The tyrosine phosphatase SHP-1 influences thymocyte selection by setting TCR signaling thresholds.
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- International Immunology, 1999, v. 11, n. 12, p. 1999, doi. 10.1093/intimm/11.12.1999
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- Article
Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma.
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- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13116-2
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- Article
Direct identification of PTEN phosphorylation sites
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- FEBS Letters, 2002, v. 528, n. 1-3, p. 145, doi. 10.1016/S0014-5793(02)03274-X
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- Article
The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer.
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- Oncogene, 2002, v. 21, n. 33, p. 5175, doi. 10.1038/sj.onc.1205522
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- Article
Noonan syndrome-causing SHP2 mutants impair ERK-dependent chondrocyte differentiation during endochondral bone growth.
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- Human Molecular Genetics, 2018, v. 27, n. 13, p. 2276, doi. 10.1093/hmg/ddy133
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- Article
Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22969-5
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- Article
Leukemogenic Ptpn11 Allele Causes Defective Erythropoiesis in Mice.
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- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109682
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- Article
Regulation of Signaling at Regions of Cell-Cell Contact by Endoplasmic Reticulum-Bound Protein-Tyrosine Phosphatase 1B.
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- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036633
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- Article
Adipocyte-Specific Protein Tyrosine Phosphatase 1B Deletion Increases Lipogenesis, Adipocyte Cell Size and Is a Minor Regulator of Glucose Homeostasis.
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- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0032700
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- Article
Regulation of protein tyrosine phosphatase 1B by sumoylation.
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- Nature Cell Biology, 2007, v. 9, n. 1, p. 80, doi. 10.1038/ncb1522
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- Article
Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca<sup>2+</sup> homeostasis.
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- EMBO Molecular Medicine, 2013, v. 5, n. 6, p. 904, doi. 10.1002/emmm.201201429
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- Article
Regulation of Kidney Development by Shp2: An Unbiased Stereological Analysis.
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- Anatomical Record: Advances in Integrative Anatomy & Evolutionary Biology, 2010, v. 293, n. 12, p. 2147, doi. 10.1002/ar.21236
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- Article