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Effect of 4-Year Antioxidant Treatment with α-Lipoic Acid in Diabetic Polyneuropathy: The NATHAN 1 Trial.
Published in:
Diabetes, 2007, v. 56, p. A2
By:
- Ziegler, Dan;
- Low, Phillip A.;
- Boulton, Andrew J.;
- Vinik, Aaron I.;
- Freeman, Roy;
- Samigullin, Rustem;
- Tritschler, Hans;
- Munzel, Ullrich;
- Maus, Joachim;
- Schuette, Klemens;
- Dyck, Peter J.
Publication type:
Article
Activation of tubular epithelial cells in diabetic nephropathy.
Published in:
2002
By:
- Morcos, Michael;
- Sayed, Ahmed A. R.;
- Bierhaus, Angelika;
- Yard, Benito;
- Waldherr, Rüdigger;
- Merz, Wolfgang;
- Kloeting, Ingrid;
- Schleicher, Erwin;
- Mentz, Stefani;
- Abd el Baki, Randa F.;
- Tritschler, Hans;
- Kasper, Michael;
- Schwenger, Vedat;
- Hamann, Andreas;
- Dugi, Klaus A.;
- Schmidt, Anne-Marie;
- Stern, David;
- Ziegler, Reinhard;
- Haering, Hans U.;
- Andrassy, Martin
Publication type:
journal article
Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.
Published in:
2001
By:
- Bierhaus, Angelika;
- Schiekofer, Stephan;
- Schwaninger, Markus;
- Andrassy, Martin;
- Humpert, Per M.;
- Chen, Jiang;
- Hong, Mei;
- Luther, Thomas;
- Henle, Thomas;
- Klöting, Ingrid;
- Morcos, Michael;
- Hofmann, Marion;
- Tritschler, Hans;
- Weigle, Bernd;
- Kasper, Michael;
- Smith, Mark;
- Perry, George;
- Schmidt, Ann-Marie;
- Stern, David M.;
- Haring, Hans-Ulrich
Publication type:
journal article
Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy.
Published in:
1999
By:
- Kishi, Yutaka;
- Schmelzer, James D.;
- Yao, Jeffrey K.;
- Zollman, Paula J.;
- Nickander, Kim K.;
- Tritschler, Hans J.;
- Low, Phillip A.;
- Kishi, Y;
- Schmelzer, J D;
- Yao, J K;
- Zollman, P J;
- Nickander, K K;
- Tritschler, H J;
- Low, P A
Publication type:
journal article
The Roles of Oxidative Stress and Antioxidant Treatment in Experimental Diabetic Neuropathy.
Published in:
Diabetes, 1997, v. 46, p. S38, doi. 10.2337/diab.46.2.s38
By:
- Low, Phillip A.;
- Nickander, Kim K.;
- Tritschler, Hans J.
Publication type:
Article
Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells.
Published in:
1997
By:
- Bierhaus, Angelika;
- Chevion, Shlomit;
- Chevion, Mordechai;
- Hofmann, Marion;
- Quehenberger, Peter;
- Illmer, Thomas;
- Luther, Thomas;
- Berentshtein, Eduard;
- Tritschler, Hans;
- Müller, Martin;
- Wahl, Peter;
- Ziegler, Reinhard;
- Nawroth, Peter P.;
- Bierhaus, A;
- Chevion, S;
- Chevion, M;
- Hofmann, M;
- Quehenberger, P;
- Illmer, T;
- Luther, T
Publication type:
journal article
Stimulation of Glucose Uptake by the Natural Coenzyme α-Lipoic Acid/Thioctic Acid.
Published in:
Diabetes, 1996, v. 45, n. 12, p. 1798, doi. 10.2337/diab.45.12.1798
By:
- Estrada, D. Elizabeth;
- Ewart, H. Stephen;
- Tsakiridis, Theodoros;
- Volchuk, Allen;
- Ramlal, Toolsie;
- Tritschler, Hans;
- Klip, Amira
Publication type:
Article
The Antioxidant α-Lipoic Acid Enhances Insulin-Stimulated Glucose Metabolism in Insulin-Resistant Rat Skeletal Muscle.
Published in:
Diabetes, 1996, v. 45, n. 8, p. 1024, doi. 10.2337/diab.45.8.1024
By:
- Jacob, Stephan;
- Streeper, Ryan S.;
- Fogt, Donovan L.;
- Hokama, Jason Y.;
- Tritschler, Hans J.;
- Dietze, Günther J.;
- Henriksen, Erik J.
Publication type:
Article
Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy.
Published in:
1995
By:
- Nagamatsu, Masaaki;
- Nickander, Kim K.;
- Schemelzer, James D.;
- Raya, Ángel;
- Wittrock, Debra A.;
- Tritschler, Hans;
- Low, Phillip A.;
- Nagamatsu, M;
- Nickander, K K;
- Schmelzer, J D;
- Raya, A;
- Wittrock, D A;
- Tritschler, H;
- Low, P A
Publication type:
journal article
Activation of Aldose Reductase in Rat Lens and Metal-Ion Chelation by Aldose Reductase Inhibitors and Lipoic Acid.
Published in:
Free Radical Research, 1996, v. 25, n. 4, p. 337, doi. 10.3109/10715769609149056
By:
- Ou, Piemian;
- Nourooz-zadeh, Jaffar;
- Tritschler, Hans-J;
- Wolff, Simon
Publication type:
Article
2D NMR of the Metabolic Antioxidant Dihydrolipoic Acid and its Derivatives.
Published in:
Free Radical Research, 1996, v. 25, n. 3, p. 195, doi. 10.3109/10715769609149045
By:
- Schepkin, Victor;
- Kawabata, Teruyuki;
- Tritschler, Hans J.;
- Packer, Lester
Publication type:
Article
Lipoic and Dihydrolipoic Acids as Antioxidants. a Critical Evaluation.
Published in:
Free Radical Research, 1994, v. 20, n. 2, p. 119, doi. 10.3109/10715769409147509
By:
- Scott, Brigitte C.;
- Aruoma, Okezie I.;
- Evans, Patricia J.;
- O'neill, Charles;
- Van Der Vliet, Albert;
- Cross, Carroll E.;
- Tritschler, Hans;
- Halliwell, Barry
Publication type:
Article
Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial.
Published in:
2011
By:
- Ziegler D;
- Low PA;
- Litchy WJ;
- Boulton AJ;
- Vinik AI;
- Freeman R;
- Samigullin R;
- Tritschler H;
- Munzel U;
- Maus J;
- Schütte K;
- Dyck PJ;
- Ziegler, Dan;
- Low, Phillip A;
- Litchy, William J;
- Boulton, Andrew J M;
- Vinik, Aaron I;
- Freeman, Roy;
- Samigullin, Rustem;
- Tritschler, Hans
Publication type:
journal article
Efficacy and Safety of Antioxidant Treatment With α-Lipoic Acid Over 4 Years in Diabetic Polyneuropathy.
Published in:
Diabetes Care, 2011, v. 34, n. 9, p. 2054, doi. 10.2337/dc11-0503
By:
- ZIEGLER, DAN;
- LOW, PHILLIP A.;
- LITCHY, WILLIAM J.;
- BOULTON, ANDREW J. M.;
- VINIK, AARON I.;
- FREEMAN, ROY;
- SAMIGULLIN, RUSTEM;
- TRITSCHLER, HANS;
- MUNZEL, ULLRICH;
- MAUS, JOACHIM;
- SCHÜTTE, KLEMENS;
- DYCK, PETER J.
Publication type:
Article
Challenges in Design of Multicenter Trials.
Published in:
Diabetes Care, 2007, v. 30, n. 10, p. 2619, doi. 10.2337/dc06-2479
By:
- Dyck, Peter J.;
- Norell, Jane E.;
- Tritschler, Hans;
- Schuette, Klemens;
- Samigullin, Rustem;
- Ziegler, Dan;
- Bastyr III, Edward J.;
- Litchy, William J.;
- O'Brien, Peter C.;
- Skljarevski, Vladimir;
- Low, Phillip A.;
- Dyck, James B.;
- Klein, Christopher J.;
- Melton III, L. Joseph
Publication type:
Article
The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid: the SYDNEY trial.
Published in:
2003
By:
- Ametov, Alexander S.;
- Barinov, Alexei;
- Dyck, Peter J.;
- Hermann, Robert;
- Kozlova, Natalia;
- Litchy, William J.;
- Low, Phillip A.;
- Nehrdich, Detlef;
- Novosadova, Maria;
- O'Brien, Peter C.;
- Reljanovic, Miroslav;
- Samigullin, Rustem;
- Schuette, Klemens;
- Strokov, Igor;
- Tritschler, Hans J.;
- Wessel, Klaus;
- Yakhno, Nikolai;
- Ziegler, Dan;
- SYDNEY Trial Study Group
Publication type:
journal article
Alpha-Tocopherol Induces Leptin Expression in Healthy Individuals and In Vitro.
Published in:
Diabetes Care, 1999, v. 22, n. 7, p. 1227, doi. 10.2337/diacare.22.7.1227a
By:
- Isermann, Berend;
- Bierhaus, Angelika;
- Tritschler, Hans;
- Ziegler, Reinhard;
- Nawroth, Peter Paul;
- Shimizu, Hiroyuki;
- Tsuchiya, Takahumi;
- Mori, Masatomo
Publication type:
Article
Alpha-Lipoic Acid Treatment Decreases Serum Lactate and Pyruvate Concentrations and Improves Glucose Effectiveness in Lean and Obese Patients With Type 2 Diabetes.
Published in:
Diabetes Care, 1999, v. 22, n. 2, p. 280, doi. 10.2337/diacare.22.2.280
By:
- Konrad, Thomas;
- Vicini, Paolo;
- Kusterer, Klaus;
- Hoflich, Angelika;
- Assadkhani, Afsaneh;
- Bohles, Hans J.;
- Sewell, Adrian;
- Tritschler, Hans J.;
- Cobelli, Claudio;
- Usadel, Klaus H.
Publication type:
Article
Insufficient glycemic control increases nuclear factor-kappa B binding activity in peripheral blood mononuclear cells isolated from patients with type 1 diabetes.
Published in:
1998
By:
- Hofmann, Marion A.;
- Schiekofer, Stephan;
- Kanitz, Michael;
- Klevesath, Martina S.;
- Joswig, Martina;
- Lee, Vong;
- Morcos, Michael;
- Tritschler, Hans;
- Ziegler, Reinhard;
- Wahl, Peter;
- Bierhaus, Angelika;
- Nawroth, Peter P.;
- Hofmann, M A;
- Schiekofer, S;
- Kanitz, M;
- Klevesath, M S;
- Joswig, M;
- Lee, V;
- Morcos, M;
- Tritschler, H
Publication type:
journal article
Hydroperoxides in plasma are reduced by intensified insulin treatment. A randomized controlled study of IDDM patients with microalbuminuria.
Published in:
1998
By:
- Berg, Tore Julsrud;
- Nourooz-Zadeh, Jaffar;
- Wolfe, Simon P.;
- Tritschler, Hans J.;
- Bangstad, Hans-Jacob;
- Hanssen, Kristian F.;
- Berg, T J;
- Nourooz-Zadeh, J;
- Wolff, S P;
- Tritschler, H J;
- Bangstad, H J;
- Hanssen, K F
Publication type:
journal article
Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily.
Published in:
2004
By:
- Bierhaus, Angelika;
- Haslbeck, Karl-Matthias;
- Humpert, Per M.;
- Liliensiek, Birgit;
- Dehmer, Thomas;
- Morcos, Michael;
- Sayed, Ahmed A. R.;
- Andrassy, Martin;
- Schiekofer, Stephan;
- Schneider, Jochen G.;
- Schulz, Jörg B.;
- Heuss, Dieter;
- Neundörler, Bernhard;
- Dierl, Stefan;
- Huber, Jochen;
- Tritschler, Hans;
- Schmidt, Ann-Marie;
- Schwaninger, Markus;
- Haering, Hans-Ulrich;
- Schleicher, Erwin
Publication type:
Abstract

Found: 21