Works matching AU Pfeifer, Alexander

Results: 88

EBI2 is a negative modulator of brown adipose tissue energy expenditure in mice and human brown adipocytes.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03201-6

By:

Copperi, Francesca;
Schleis, Inna;
Roumain, Martin;
Muccioli, Giulio G.;
Casola, Stefano;
Klingenspor, Martin;
Pfeifer, Alexander;
Gnad, Thorsten

Publication type:

Article

Author Correction: PDGF regulates guanylate cyclase expression and cGMP signaling in vascular smooth muscle.

Published in:

2022

By:

Hildebrand, Staffan;
Ibrahim, Mohamed;
Schlitzer, Andreas;
Maegdefessel, Lars;
Röll, Wilhelm;
Pfeifer, Alexander

Publication type:

Correction Notice

PDGF regulates guanylate cyclase expression and cGMP signaling in vascular smooth muscle.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03140-2

By:

Hildebrand, Staffan;
Ibrahim, Mohamed;
Schlitzer, Andreas;
Maegdefessel, Lars;
Röll, Wilhelm;
Pfeifer, Alexander

Publication type:

Article

Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33487-8

By:

Muth, Doreen;
Corman, Victor Max;
Roth, Hanna;
Binger, Tabea;
Dijkman, Ronald;
Gottula, Lina Theresa;
Gloza-Rausch, Florian;
Balboni, Andrea;
Battilani, Mara;
Rihtarič, Danijela;
Toplak, Ivan;
Ameneiros, Ramón Seage;
Pfeifer, Alexander;
Thiel, Volker;
Drexler, Jan Felix;
Müller, Marcel Alexander;
Drosten, Christian

Publication type:

Article

Different MicroRNA Profiles in Chronic Epilepsy Versus Acute Seizure Mouse Models.

Published in:

Journal of Molecular Neuroscience, 2015, v. 55, n. 2, p. 466, doi. 10.1007/s12031-014-0368-6

By:

Kretschmann, Anita;
Danis, Benedicte;
Andonovic, Lidija;
Abnaof, Khalid;
Rikxoort, Marijke;
Siegel, Franziska;
Mazzuferi, Manuela;
Godard, Patrice;
Hanon, Etienne;
Fröhlich, Holger;
Kaminski, Rafal;
Foerch, Patrik;
Pfeifer, Alexander

Publication type:

Article

The obesity pandemic and its impact on non-communicable disease burden.

Published in:

Pflügers Archiv: European Journal of Physiology, 2025, v. 477, n. 5, p. 657, doi. 10.1007/s00424-025-03066-8

By:

Hildebrand, Staffan;
Pfeifer, Alexander

Publication type:

Article

Fat tissues, the brite and the dark sides.

Published in:

Pflügers Archiv: European Journal of Physiology, 2016, v. 468, n. 11/12, p. 1803, doi. 10.1007/s00424-016-1884-8

By:

Chen, Yong;
Pan, Ruping;
Pfeifer, Alexander

Publication type:

Article

The enhancement of HCN channel instantaneous current facilitated by slow deactivation is regulated by intracellular chloride concentration.

Published in:

Pflügers Archiv: European Journal of Physiology, 2006, v. 452, n. 6, p. 718, doi. 10.1007/s00424-006-0095-0

By:

Mistrík, Pavel;
Pfeifer, Alexander;
Biel, Martin

Publication type:

Article

The RGD motif in fibronectin is essential for development but dispensable for fibril assembly.

Published in:

Journal of Cell Biology, 2007, v. 178, n. 1, p. 167, doi. 10.1083/jcb.200703021

By:

Takahashi, Seiichiro;
Leiss, Michael;
Moser, Markus;
Fässler, Reinhard;
Ohashi, Tomoo;
Erickson, Harold P.;
Kitao, Tomoe;
Takagi, Junichi;
Heckmann, Dominik;
Kessler, Horst;
Pfeifer, Alexander

Publication type:

Article

CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1308456

By:

Jaeckstein, Michelle Y.;
Schulze, Isabell;
Zajac, Michael Wolfgang;
Heine, Markus;
Mann, Oliver;
Pfeifer, Alexander;
Heeren, Joerg

Publication type:

Article

Brown Fat Develops a Brite Future.

Published in:

Obesity Facts: The European Journal of Obesity, 2012, v. 5, n. 6, p. 890, doi. 10.1159/000346337

By:

Klingenspor, Martin;
Herzig, Stephan;
Pfeifer, Alexander

Publication type:

Article

Filarial Infection or Antigen Administration Improves Glucose Tolerance in Diet-Induced Obese Mice.

Published in:

Journal of Innate Immunity, 2016, v. 8, n. 6, p. 601, doi. 10.1159/000448401

By:

Berbudi, afiat;
Surendar, Jayagopi;
ajendra, Jesuthas;
Gondorf, Fabian;
Schmidt, David;
Neumann, anna-Lena;
Wardani, ajeng P.F.;
Layland, Laura E.;
Hoffmann, Linda S.;
Pfeifer, alexander;
Hoerauf, achim;
Hübner, Marc P.

Publication type:

Article

Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.

Published in:

Science Signaling, 2019, v. 12, n. 573, p. N.PAG, doi. 10.1126/scisignal.aau5948

By:

Annala, Suvi;
Eryilmaz, Funda;
Patt, Julian;
Pfeil, Eva M.;
Häberlein, Felix;
Schrage, Ramona;
Heycke, Nina;
Rick, Ulrike;
Kostenis, Evi;
Feng, Xiaodong;
Gutkind, J. Silvio;
Shridhar, Naveen;
Slodczyk, Tanja;
Tüting, Thomas;
Gaffal, Evelyn;
Yang, JuHee;
Pfeifer, Alexander;
Cervantes-Villagrana, Rodolfo Daniel;
Vázquez-Prado, José;
Inoue, Asuka

Publication type:

Article

Combined inhibition of PI3Kβ and PI3Kγ reduces fat mass by enhancing α-MSH--dependent sympathetic drive.

Published in:

Science Signaling, 2014, v. 7, n. 352, p. 1, doi. 10.1126/scisignal.2005485

By:

Perino, Alessia;
Beretta, Martina;
Kilić, Ana;
Ghigo, Alessandra;
Carnevale, Daniela;
Repetto, Ivan Enrico;
Braccini, Laura;
Longo, Dario;
Liebig-Gonglach, Michaela;
Zaglia, Tania;
Iacobucci, Roberta;
Mongillo, Marco;
Wetzker, Reinhard;
Bauer, Michael;
Aime, Silvio;
Vercelli, Alessandro;
Lembo, Giuseppe;
Pfeifer, Alexander;
Hirsch, Emilio

Publication type:

Article

Lentiviral Vector Mediated Thymidine Kinase Expression in Pluripotent Stem Cells Enables Removal of Tumorigenic Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0070543

By:

Lim, Tiong-Ti;
Geisen, Caroline;
Hesse, Michael;
Fleischmann, Bernd K.;
Zimmermann, Katrin;
Pfeifer, Alexander

Publication type:

Article

Impaired Channel Targeting and Retinal Degeneration in Mice Lacking the Cyclic Nucleotide-Gated Channel Subunit CNGB1.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 1, p. 130, doi. 10.1523/JNEUROSCI.3764-04.2005

By:

Hüttl, Sabine;
Michalakis, Stylianos;
Seeliger, Mathias;
Dong-Gen Luo;
Acar, Niyazi;
Geiger, Heidi;
Hudl, Kristiane;
Mader, Robert;
Haverkamp, Silke;
Moser, Markus;
Pfeifer, Alexander;
Gerstner, Andrea;
King-Wai Yau;
Biel, Martin

Publication type:

Article

Mena and Vasodilator-Stimulated Phosphoprotein Are Required for Multiple Actin-Dependent Processes That Shape the Vertebrate Nervous System.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 37, p. 8029, doi. 10.1523/JNEUROSCI.1057-04.2004

By:

Menzies, A. Shiela;
Aszodi, Attila;
Williams, Scott E.;
Pfeifer, Alexander;
Wehman, Ann M.;
Keow Lin Goh;
Mason, Carol A.;
Fassler, Reinhard;
Gertler, Frank B.

Publication type:

Article

Regulation of Brown Adipose Tissue and Beige Fat by the Adenosine A2B Receptor 8.5.5.

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04815

By:

Gnad, Thorsten;
Pfeifer, Alexander

Publication type:

Article

Increased cGMP promotes healthy expansion and browning of white adipose tissue.

Published in:

FASEB Journal, 2013, v. 27, n. 4, p. 1621, doi. 10.1096/fj.12-221580

By:

Mitschke, Michaela M.;
Hoffmann, Linda S.;
Gnad, Thorsten;
Scholz, Daniela;
Kruithoff, Katja;
Mayer, Peter;
Haas, Bodo;
Sassmann, Antonia;
Pfeifer, Alexander;
Kilić, Ana

Publication type:

Article

B2 bradykinin receptors in cultured neonatal rat cardiomyocytes mediate a negative chronotropic and negative inotropic response.

Published in:

1996

By:

Kasel, Albert M.;
Faußner, Alexander;
Pfeifer, Alexander;
Müller, Ursula;
Werdan, Karl;
Roscher, Adelbert A.;
Kasel, A M;
Faussner, A;
Pfeifer, A;
Müller, U;
Werdan, K;
Roscher, A A

Publication type:

journal article

A cGMP Kinase Mutant with Increased Sensitivity to the Protein Kinase Inhibitor Peptide PKI(5-24).

Published in:

Biological Chemistry, 1996, v. 377, n. 7/8, p. 514

By:

Ruth, Peter;
Kamm, Simone;
Nau, Uschi;
Pfeifer, Alexander;
Hofmann, Franz

Publication type:

Article

Efficient and graded gene expression in glia and neurons of primary cerebellar cultures transduced by lentiviral vectors.

Published in:

Histochemistry & Cell Biology, 2015, v. 143, n. 1, p. 109, doi. 10.1007/s00418-014-1260-8

By:

Kumar, Sujeet;
Zimmermann, Katrin;
Hioki, Hiroyuki;
Pfeifer, Alexander;
Baader, Stephan

Publication type:

Article

Distribution and expression of porcine endogenous retroviruses in multi-transgenic pigs generated for xenotransplantation.

Published in:

Xenotransplantation, 2009, v. 16, n. 2, p. 64, doi. 10.1111/j.1399-3089.2009.00515.x

By:

Dieckhoff, Britta;
Kessler, Barbara;
Jobst, Danny;
Kues, Wilfried;
Petersen, Björn;
Pfeifer, Alexander;
Kurth, Reinhard;
Niemann, Heiner;
Wolf, Eckhard;
Denner, Joachim

Publication type:

Article

Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

Published in:

2020

By:

Kuschak, Markus;
Namasivayam, Vigneshwaran;
Rafehi, Muhammad;
Voss, Jan H.;
Garg, Jaspal;
Schlegel, Jonathan G.;
Abdelrahman, Aliaa;
Kehraus, Stefan;
Reher, Raphael;
Küppers, Jim;
Sylvester, Katharina;
Hinz, Sonja;
Matthey, Michaela;
Wenzel, Daniela;
Fleischmann, Bernd K.;
Pfeifer, Alexander;
Inoue, Asuka;
Gütschow, Michael;
König, Gabriele M.;
Müller, Christa E.

Publication type:

journal article

Decoding Signaling and Function of the Orphan G Protein--Coupled Receptor GPR17 with a Small-Molecule Agonist.

Published in:

Science Signaling, 2013, v. 6, n. 298, p. 1, doi. 10.1126/scisignal.2004350

By:

Hennen, Stephanie;
Haibo Wang;
Peters, Lucas;
Merten, Nicole;
Simon, Katharina;
Spinrath, Andreas;
Blättermann, Stefanie;
Akkari, Rhalid;
Schrage, Ramona;
Schröder, Ralf;
Schulz, Daniel;
Vermeiren, Celine;
Zimmermann, Katrin;
Kehraus, Stefan;
Drewke, Christel;
Pfeifer, Alexander;
König, Gabriele M.;
Mohr, Klaus;
Gillard, Michel;
Müller, Christa E.

Publication type:

Article

A VASP-Rac-Soluble Guanylyl Cyclase Pathway Controls cGMP Production in Adipocytes.

Published in:

Science Signaling, 2012, v. 5, n. 239, p. 1, doi. 10.1126/scisignal.2002867

By:

Jennissen, Katja;
Siegel, Franziska;
Liebig-Gonglach, Michaela;
Hermann, Michaela-Rosemarie;
Kipschull, Stefanie;
van Dooren, Sander;
Kunz, Wolfram S.;
Fässler, Reinhard;
Pfeifer, Alexander

Publication type:

Article

Cyclic GMP and Protein Kinase G Control a Src-Containing Mechanosome in Osteoblasts.

Published in:

Science Signaling, 2010, v. 3, n. 153, p. 1, doi. 10.1126/scisignal.2001423

By:

Rangaswami, Hema;
Schwappacher, Raphaela;
Marathe, Nisha;
Shunhui Zhuang;
Casteel, Darren E.;
Haas, Bodo;
Yong Chen;
Pfeifer, Alexander;
Kato, Hisashi;
Shattil, Sanford;
Boss, Gerry R.;
Pilz, Renate B.

Publication type:

Article

Protein Kinase G Controls Brown Fat Cell Differentiation and Mitochondrial Biogenesis.

Published in:

Science Signaling, 2009, v. 2, n. 99, p. 1, doi. 10.1126/scisignal.2000511

By:

Haas, Bodo;
Mayer, Peter;
Jennissen, Katja;
Scholz, Daniela;
Diaz, Mauricio Berriel;
Bloch, Wilhelm;
Herzig, Stephan;
Fässler, Reinhard;
Pfeifer, Alexander

Publication type:

Article

KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 4, p. 1027, doi. 10.1093/brain/aws045

By:

Brockschmidt, Antje;
Trost, Detlef;
Peterziel, Heike;
Zimmermann, Katrin;
Ehrler, Marion;
Grassmann, Henriette;
Pfenning, Philipp-Niclas;
Waha, Anke;
Wohlleber, Dirk;
Brockschmidt, Felix F.;
Jugold, Manfred;
Hoischen, Alexander;
Kalla, Claudia;
Waha, Andreas;
Seifert, Gerald;
Knolle, Percy A.;
Latz, Eicke;
Hans, Volkmar H.;
Wick, Wolfgang;
Pfeifer, Alexander

Publication type:

Article

Highly efficient concentration of lenti- and retroviral vector preparations by membrane adsorbers and ultrafiltration.

Published in:

BMC Biotechnology, 2011, v. 11, n. 1, p. 55, doi. 10.1186/1472-6750-11-55

By:

Zimmermann, Katrin;
Scheibe, Oliver;
Kocourek, Andreas;
Muelich, Jutta;
Jurkiewicz, Elke;
Pfeifer, Alexander

Publication type:

Article

Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 6, p. 1490, doi. 10.1172/JCI29882

By:

Algül, Hana;
Treiber, Matthias;
Lesina, Marina;
Nakhai, Hassan;
Saur, Dieter;
Geisler, Fabian;
Pfeifer, Alexander;
Paxian, Stephan;
Schmid, Roland M.

Publication type:

Article

Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice.

Published in:

Journal of Clinical Investigation, 2006, v. 116, n. 12, p. 3204, doi. 10.1172/JCI29236

By:

Pfeifer, Alexander;
Eigenbrod, Sabina;
Al-Khadra, Saba;
Hofmann, Andreas;
Mitteregger, Gerda;
Moser, Markus;
Bertsch, Uwe;
Kretzschmar, Hans

Publication type:

Article

Differential expression of miR-184 in temporal lobe epilepsy patients with and without hippocampal sclerosis - Influence on microglial function.

Published in:

Scientific Reports, 2016, p. 33943, doi. 10.1038/srep33943

By:

Danis, Bénédicte;
van Rikxoort, Marijke;
Kretschmann, Anita;
Zhang, Jiong;
Godard, Patrice;
Andonovic, Lidija;
Siegel, Franziska;
Niehusmann, Pitt;
Hanon, Etienne;
Delev, Daniel;
von Lehe, Marec;
Kaminski, Rafal M.;
Pfeifer, Alexander;
Foerch, Patrik

Publication type:

Article

TRPM4-mediated control of FcεRI-evoked Ca2+ elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells.

Published in:

Scientific Reports, 2016, p. 32981, doi. 10.1038/srep32981

By:

Rixecker, Torben;
Mathar, Ilka;
Medert, Rebekka;
Mannebach, Stefanie;
Pfeifer, Alexander;
Lipp, Peter;
Tsvilovskyy, Volodymyr;
Freichel, Marc

Publication type:

Article

Metabolic role of dipeptidyl peptidase 4 (DPP4) in primary human (pre)adipocytes.

Published in:

Scientific Reports, 2016, p. 23074, doi. 10.1038/srep23074

By:

Zilleßen, Pia;
Celner, Jennifer;
Kretschmann, Anita;
Pfeifer, Alexander;
Racké, Kurt;
Mayer, Peter

Publication type:

Article

Influence of PKG on insulin signalling and GSK3 phosphorylation in SH-SY5Y cells.

Published in:

2013

By:

Sanya, Abhishek;
Lochmatter, Didier;
Preußner, Anne;
Pfeifer, Alexander

Publication type:

Abstract

Phosphodiesterase 5 is main regulator of brown adipocyte differentiation.

Published in:

2013

By:

Kilić, Ana;
Gnad, Thorsten;
Hoffmann, Linda S.;
Pfeifer, Alexander

Publication type:

Abstract

The role of VASP in cGMP-mediated vascular smooth muscle relaxation.

Published in:

2013

By:

Hildebrand, Staffan;
Zimmermann, Katrin;
Wenzel, Daniela;
Fleischmann, Bernd K.;
Pfeifer, Alexander

Publication type:

Abstract

Guanylyl cyclase-B plays an important role in adipogenesis and "browning" of white fat.

Published in:

2013

By:

Glöde, Anja;
Kilić, Ana;
Burnett, John C.;
Pfeifer, Alexander

Publication type:

Abstract

The soluble guanylyl cyclase stimulator BAY 41- 2272 increases differentiation and function of brown adipocytes.

Published in:

2013

By:

Etzrodt, Jennifer;
Hoffmann, Linda S.;
Friebe, Andreas;
Pfeifer, Alexander

Publication type:

Abstract

A possible crosstalk between cGMP pathway and Activin receptor-like kinase 7 (Alk7) in adipocytes.

Published in:

2013

By:

Balkow, Aileen;
Jagow, Johanna;
Kilic, Ana;
Pfeifer, Alexander

Publication type:

Abstract

Role of cGMP in fat and metabolism.

Published in:

2013

By:

Pfeifer, Alexander;
Kilić, Ana;
Hoffmann, Linda

Publication type:

Abstract

Neuronal fate determinants of adult olfactory bulb neurogenesis.

Published in:

Nature Neuroscience, 2005, v. 8, n. 7, p. 865, doi. 10.1038/nn1479

By:

Hack, Michael A.;
Saghatelyan, Armen;
de Chevigny, Antoine;
Pfeifer, Alexander;
Ashery-Padan, Ruth;
Lledo, Pierre-Marie;
Götz, Magdalena

Publication type:

Article

Impaired relaxation of stomach smooth muscle in mice lacking cyclic GMP-dependent protein kinase I.

Published in:

British Journal of Pharmacology, 2000, v. 129, n. 2, p. 395, doi. 10.1038/sj.bjp.0703061

By:

Ny, Lars;
Pfeifer, Alexander;
Aszòdi, Attila;
Ahmad, Marianne;
Alm, Per;
Hedlund, Petter;
Fässler, Reinhard;
Andersson, Karl-Erik

Publication type:

Article

Tissue Clearing and Light Sheet Microscopy: Imaging the Unsectioned Adult Zebra Finch Brain at Cellular Resolution.

Published in:

Frontiers in Neuroanatomy, 2019, p. N.PAG, doi. 10.3389/fnana.2019.00013

By:

Rocha, Mariana Diales;
Düring, Daniel Normen;
Bethge, Philipp;
Voigt, Fabian F.;
Hildebrand, Staffan;
Helmchen, Fritjof;
Pfeifer, Alexander;
Hahnloser, Richard Hans Robert;
Gahr, Manfred

Publication type:

Article

The role of compartmentalized β‐AR/cAMP signaling in the regulation of lipolysis in white and brown adipocytes.

Published in:

FEBS Journal, 2025, v. 292, n. 2, p. 261, doi. 10.1111/febs.17157

By:

De Jong, Kirstie A.;
Siddig, Sana;
Pfeifer, Alexander;
Nikolaev, Viacheslav O.

Publication type:

Article

Combination of phosphodiesterase‐5‐inhibitors and beta blockers improves experimental portal hypertension and erectile dysfunction.

Published in:

Liver International, 2020, v. 40, n. 9, p. 2228, doi. 10.1111/liv.14586

By:

Uschner, Frank E.;
Glückert, Kathleen;
Paternostro, Rafael;
Gnad, Thorsten;
Schierwagen, Robert;
Mandorfer, Mattias;
Magdaleno, Fernando;
Ortiz, Cristina;
Schwarzkopf, Katharina;
Kamath, Patrick S.;
Alessandria, Carlo;
Boesecke, Christoph;
Pfeifer, Alexander;
Reiberger, Thomas;
Kreisel, Wolfgang;
Sauerbruch, Tilman;
Ferlitsch, Arnulf;
Trebicka, Jonel;
Klein, Sabine

Publication type:

Article

Regulation of human brown adipose tissue by adenosine and A2A receptors - studies with [15O]H2O and [11C]TMSX PET/CT.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2019, v. 46, n. 3, p. 743, doi. 10.1007/s00259-018-4120-2

By:

Lahesmaa, Minna;
Oikonen, Vesa;
Helin, Semi;
Luoto, Pauliina;
U Din, Mueez;
Pfeifer, Alexander;
Nuutila, Pirjo;
Virtanen, Kirsi A.

Publication type:

Article

Correction to: Regulation of human brown adipose tissue by adenosine and A2A receptors - studies with [15O]H2O and [11C]TMSX PET/CT.

Published in:

2018

By:

Lahesmaa, Minna;
Oikonen, Vesa;
Helin, Semi;
Luoto, Pauliina;
U Din, Mueez;
Pfeifer, Alexander;
Nuutila, Pirjo;
Virtanen, Kirsi A.

Publication type:

Correction Notice

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 15, p. 2928, doi. 10.1093/hmg/ddr197

By:

Araujo, Julieta;
Breuer, Peter;
Dieringer, Susanne;
Krauss, Sybille;
Dorn, Stephanie;
Zimmermann, Katrin;
Pfeifer, Alexander;
Klockgether, Thomas;
Wuellner, Ullrich;
Evert, Bernd O.

Publication type:

Article