Works matching DE "PHYSIOLOGICAL effects of hypoglycemic agents"

Results: 195

Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones.
Published in:
Nature, 2014, v. 511, n. 7507, p. 94, doi. 10.1038/nature13297
By:
- Maianti, Juan Pablo;
- McFedries, Amanda;
- Foda, Zachariah H.;
- Kleiner, Ralph E.;
- Du, Xiu Quan;
- Leissring, Malcolm A.;
- Tang, Wei-Jen;
- Charron, Maureen J.;
- Seeliger, Markus A.;
- Saghatelian, Alan;
- Liu, David R.
Publication type:
Article
A safety update on sodium glucose co‐transporter 2 inhibitors.
Published in:
Diabetes, Obesity & Metabolism, 2019, v. 21, p. 34, doi. 10.1111/dom.13611
By:
- Fitchett, David
Publication type:
Article
Comparative risk of genital infections associated with sodium‐glucose co‐transporter‐2 inhibitors.
Published in:
Diabetes, Obesity & Metabolism, 2019, v. 21, n. 2, p. 434, doi. 10.1111/dom.13531
By:
- Dave, Chintan V.;
- Schneeweiss, Sebastian;
- Patorno, Elisabetta
Publication type:
Article
Effects on clinical outcomes of intensifying triple oral antidiabetic drug (OAD) therapy by initiating insulin versus enhancing OAD therapy in patients with type 2 diabetes: A nationwide population‐based, propensity‐score‐matched cohort study
Published in:
Diabetes, Obesity & Metabolism, 2019, v. 21, n. 2, p. 312, doi. 10.1111/dom.13525
By:
- Kuo, Shihchen;
- Yang, Chun‐Ting;
- Wu, Jin‐Shang;
- Ou, Huang‐Tz
Publication type:
Article
Safety and tolerability of dapagliflozin, saxagliptin and metformin in combination: <italic>Post‐hoc</italic> analysis of concomitant add‐on versus sequential add‐on to metformin and of triple versus dual therapy with metformin.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 6, p. 1542, doi. 10.1111/dom.13258
By:
- Del Prato, Stefano;
- Rosenstock, Julio;
- Garcia‐Sanchez, Ricardo;
- Iqbal, Nayyar;
- Chen, Hungta;
- Hansen, Lars;
- Johnsson, Eva;
- Mathieu, Chantal
Publication type:
Article
Long-term maintenance of efficacy of dapagliflozin in patients with type 2 diabetes mellitus and cardiovascular disease.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 8, p. 766, doi. 10.1111/dom.12666
By:
- Leiter, L. A.;
- Cefalu, W. T.;
- Bruin, T. W. A.;
- Xu, J.;
- Parikh, S.;
- Johnsson, E.;
- Gause‐Nilsson, I.
Publication type:
Article
Comparative cardiovascular safety of glucagon-like peptide-1 receptor agonists versus other antidiabetic drugs in routine care: a cohort study.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 8, p. 755, doi. 10.1111/dom.12665
By:
- Patorno, E.;
- Everett, B. M.;
- Goldfine, A. B.;
- Glynn, R. J.;
- Liu, J.;
- Gopalakrishnan, C.;
- Kim, S. C.
Publication type:
Article
Efficacy and safety of combination therapy with vildagliptin and metformin versus metformin uptitration in Chinese patients with type 2 diabetes inadequately controlled with metformin monotherapy: a randomized, open-label, prospective study ( VISION).
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 8, p. 775, doi. 10.1111/dom.12667
By:
- Ji, L.‐N.;
- Pan, C.‐Y.;
- Lu, J.‐M.;
- Li, H.;
- Zhu, D.‐L.;
- Li, Q.;
- Li, Q.‐F.;
- Peng, Y.‐D.;
- Tian, H.‐M.;
- Yao, C.;
- Zhao, Z.‐G.;
- Wang, L.;
- Wang, B.‐H.
Publication type:
Article
Efficacy and safety of titrated canagliflozin in patients with type 2 diabetes mellitus inadequately controlled on metformin and sitagliptin.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 8, p. 812, doi. 10.1111/dom.12684
By:
- Rodbard, H. W.;
- Seufert, J.;
- Aggarwal, N.;
- Cao, A.;
- Fung, A.;
- Pfeifer, M.;
- Alba, M.
Publication type:
Article
Similar efficacy and safety of once-weekly dulaglutide in patients with type 2 diabetes aged ≥65 and <65 years.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 8, p. 820, doi. 10.1111/dom.12687
By:
- Boustani, M. A.;
- Pittman, I.;
- Yu, M.;
- Thieu, V. T.;
- Varnado, O. J.;
- Juneja, R.
Publication type:
Article
Efficacy and safety of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes mellitus: systematic review and network meta-analysis.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 8, p. 783, doi. 10.1111/dom.12670
By:
- Zaccardi, F.;
- Webb, D. R.;
- Htike, Z. Z.;
- Youssef, D.;
- Khunti, K.;
- Davies, M. J.
Publication type:
Article
Differential effects of once-weekly glucagon-like peptide-1 receptor agonist dulaglutide and metformin on pancreatic β-cell and insulin sensitivity during a standardized test meal in patients with type 2 diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 8, p. 834, doi. 10.1111/dom.12671
By:
- Mari, A.;
- Del Prato, S.;
- Ludvik, B.;
- Milicevic, Z.;
- Peña, A.;
- Shurzinske, L.;
- Karanikas, C. A.;
- Pechtner, V.
Publication type:
Article
Effects of multiple ascending doses of the glucagon receptor antagonist PF-06291874 in patients with type 2 diabetes mellitus.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 8, p. 795, doi. 10.1111/dom.12672
By:
- Kazierad, D. J.;
- Bergman, A.;
- Tan, B.;
- Erion, D. M.;
- Somayaji, V.;
- Lee, D. S.;
- Rolph, T.
Publication type:
Article
Change in glycated haemoglobin levels after initiating second-line therapy in type 2 diabetes: a primary care database study.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 8, p. 840, doi. 10.1111/dom.12673
By:
- Rathmann, W.;
- Bongaerts, B.;
- Kostev, K.
Publication type:
Article
Efficacy and safety of teneligliptin, a novel dipeptidyl peptidase-4 inhibitor, in Korean patients with type 2 diabetes mellitus: a 24-week multicentre, randomized, double-blind, placebo-controlled phase III trial.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 5, p. 528, doi. 10.1111/dom.12631
By:
- Hong, S.;
- Park, C.‐Y.;
- Han, K. A.;
- Chung, C. H.;
- Ku, B. J.;
- Jang, H. C.;
- Ahn, C. W.;
- Lee, M.‐K.;
- Moon, M. K.;
- Son, H. S.;
- Lee, C. B.;
- Cho, Y.‐W.;
- Park, S.‐W.
Publication type:
Article
Once-weekly glucagon-like peptide-1 receptor agonist dulaglutide significantly decreases glycated haemoglobin compared with once-daily liraglutide in Japanese patients with type 2 diabetes: 52 weeks of treatment in a randomized phase III study.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 3, p. 249, doi. 10.1111/dom.12602
By:
- Odawara, M.;
- Miyagawa, J.;
- Iwamoto, N.;
- Takita, Y.;
- Imaoka, T.;
- Takamura, T.
Publication type:
Article
Patient-reported outcomes among patients with type 2 diabetes mellitus treated with dapagliflozin in a triple-therapy regimen for 52 weeks.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 3, p. 306, doi. 10.1111/dom.12604
By:
- Grandy, S.;
- Sternhufvud, C.;
- Ryden, A.;
- Sugg, J.;
- Rohwedder, K.
Publication type:
Article
Use of incretin agents and risk of pancreatic cancer: a population-based cohort study.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 3, p. 258, doi. 10.1111/dom.12605
By:
- Knapen, L. M.;
- van Dalem, J.;
- Keulemans, Y. C.;
- van Erp, N. P.;
- Bazelier, M. T.;
- De Bruin, M. L.;
- Leufkens, H. G. M.;
- Croes, S.;
- Neef, C.;
- de Vries, F.;
- Driessen, J. H. M.
Publication type:
Article
Ten-year observational follow-up of PROactive: a randomized cardiovascular outcomes trial evaluating pioglitazone in type 2 diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 3, p. 266, doi. 10.1111/dom.12608
By:
- Erdmann, E.;
- Harding, S.;
- Lam, H.;
- Perez, A.
Publication type:
Article
Treatment intensification with an insulin degludec ( IDeg)/insulin aspart ( IAsp) co-formulation twice daily compared with basal IDeg and prandial IAsp in type 2 diabetes: a randomized, controlled phase III trial.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 3, p. 274, doi. 10.1111/dom.12609
By:
- Rodbard, H. W.;
- Cariou, B.;
- Pieber, T. R.;
- Endahl, L. A.;
- Zacho, J.;
- Cooper, J. G.
Publication type:
Article
Comparison of the pharmacokinetics and pharmacodynamics of dapagliflozin in patients with type 1 versus type 2 diabetes mellitus.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 3, p. 236, doi. 10.1111/dom.12594
By:
- Tang, W.;
- Leil, T. A.;
- Johnsson, E.;
- Boulton, D. W.;
- LaCreta, F.
Publication type:
Article
Cardiovascular and non-cardiovascular safety of dipeptidyl peptidase-4 inhibition: a meta-analysis of randomized controlled cardiovascular outcome trials.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 3, p. 295, doi. 10.1111/dom.12595
By:
- Abbas, A. S.;
- Dehbi, H.‐M.;
- Ray, K. K.
Publication type:
Article
Frequency of cancer events with saxagliptin in the SAVOR-TIMI 53 trial.
Published in:
Diabetes, Obesity & Metabolism, 2016, v. 18, n. 2, p. 186, doi. 10.1111/dom.12582
By:
- Leiter, L. A.;
- Teoh, H.;
- Mosenzon, O.;
- Cahn, A.;
- Hirshberg, B.;
- Stahre, C. A. M.;
- Hoekstra, J. B. L.;
- Alvarsson, M.;
- Im, K.;
- Scirica, B. M.;
- Bhatt, D. L.;
- Raz, I.
Publication type:
Article
Bioavailability of insulin detemir and human insulin at the level of peripheral interstitial fluid in humans, assessed by open-flow microperfusion.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 12, p. 1166, doi. 10.1111/dom.12551
By:
- Bodenlenz, M.;
- Ellmerer, M.;
- Schaupp, L.;
- Jacobsen, L. V.;
- Plank, J.;
- Brunner, G. A.;
- Wutte, A.;
- Aigner, B.;
- Mautner, S. I.;
- Pieber, T. R.
Publication type:
Article
Comparison of basal insulin therapies with regard to the risk of acute myocardial infarction in patients with type 2 diabetes: an observational cohort study.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 12, p. 1158, doi. 10.1111/dom.12554
By:
- Kollhorst, B.;
- Behr, S.;
- Enders, D.;
- Dippel, F.‐W.;
- Theobald, K.;
- Garbe, E.
Publication type:
Article
Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 12, p. 1180, doi. 10.1111/dom.12572
By:
- Chilton, R.;
- Tikkanen, I.;
- Cannon, C. P.;
- Crowe, S.;
- Woerle, H. J.;
- Broedl, U. C.;
- Johansen, O. E.
Publication type:
Article
A novel and selective sodium-glucose cotransporter-2 inhibitor, tofogliflozin, improves glycaemic control and lowers body weight in patients with type 2 diabetes mellitus.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 10, p. 984, doi. 10.1111/dom.12538
By:
- Ikeda, S.;
- Takano, Y.;
- Cynshi, O.;
- Tanaka, R.;
- Christ, A. D.;
- Boerlin, V.;
- Beyer, U.;
- Beck, A.;
- Ciorciaro, C.;
- Meyer, M.;
- Kadowaki, T.
Publication type:
Article
Efficacy and tolerability of saxagliptin compared with glimepiride in elderly patients with type 2 diabetes: a randomized, controlled study (GENERATION).
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 7, p. 630, doi. 10.1111/dom.12461
By:
- Schernthaner, G.;
- Durán‐Garcia, S.;
- Hanefeld, M.;
- Langslet, G.;
- Niskanen, L.;
- Östgren, C. J.;
- Malvolti, E.;
- Hardy, E.
Publication type:
Article
Safety and effectiveness of non-insulin glucose-lowering agents in the treatment of people with type 2 diabetes who observe Ramadan: a systematic review and meta-analysis.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 7, p. 639, doi. 10.1111/dom.12462
By:
- Gray, L. J.;
- Dales, J.;
- Brady, E. M.;
- Khunti, K.;
- Hanif, W.;
- Davies, M. J.
Publication type:
Article
Long-term treatment with empagliflozin as add-on to oral antidiabetes therapy in Japanese patients with type 2 diabetes mellitus.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 7, p. 665, doi. 10.1111/dom.12464
By:
- Araki, E.;
- Tanizawa, Y.;
- Tanaka, Y.;
- Taniguchi, A.;
- Koiwai, K.;
- Kim, G.;
- Salsali, A.;
- Woerle, H. J.;
- Broedl, U. C.
Publication type:
Article
Incretin-based medications for type 2 diabetes: an overview of reviews.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 7, p. 649, doi. 10.1111/dom.12465
By:
- Gamble, J.‐M.;
- Clarke, A.;
- Myers, K. J.;
- Agnew, M. D.;
- Hatch, K.;
- Snow, M. M.;
- Davis, E. M.
Publication type:
Article
Efficacy and safety of fasiglifam ( TAK-875), a G protein-coupled receptor 40 agonist, in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise: a randomized, double-blind, placebo-controlled, phase III trial.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 7, p. 675, doi. 10.1111/dom.12467
By:
- Kaku, K.;
- Enya, K.;
- Nakaya, R.;
- Ohira, T.;
- Matsuno, R.
Publication type:
Article
Faster-acting insulin aspart: earlier onset of appearance and greater early pharmacokinetic and pharmacodynamic effects than insulin aspart.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 7, p. 682, doi. 10.1111/dom.12468
By:
- Heise, T.;
- Hövelmann, U.;
- Brøndsted, L.;
- Adrian, C. L.;
- Nosek, L.;
- Haahr, H.
Publication type:
Article
A systematic review of acute pancreatitis as an adverse event of type 2 diabetes drugs: from hard facts to a balanced position.
Published in:
Diabetes, Obesity & Metabolism, 2014, v. 16, n. 11, p. 1041, doi. 10.1111/dom.12297
By:
- Giorda, C. B.;
- Nada, E.;
- Tartaglino, B.;
- Marafetti, L.;
- Gnavi, R.
Publication type:
Article
The amino acid response to a mixed meal in patients with type 2 diabetes: effect of sitagliptin treatment.
Published in:
Diabetes, Obesity & Metabolism, 2014, v. 16, n. 11, p. 1140, doi. 10.1111/dom.12350
By:
- Muscelli, E.;
- Frascerra, S.;
- Casolaro, A.;
- Baldi, S.;
- Mari, A.;
- Gall, W.;
- Cobb, J.;
- Ferrannini, E.
Publication type:
Article
Oxidative stress as a covariate of recovery in diabetes therapy.
Published in:
Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00089
By:
- Kulkarni, R.;
- Acharya, J.;
- Ghaskadbi, S.;
- Goel, P.
Publication type:
Article
Glycaemic control and glucose-lowering therapy in diabetic patients with kidney disease.
Published in:
African Journal of Diabetes Medicine, 2014, v. 22, n. 1, p. 12
By:
- Mpondo, B.
Publication type:
Article
A set of four simple performance measures reflecting adherence to guidelines predicts hospitalization: a claims-based cohort study of patients with diabetes.
Published in:
Patient Preference & Adherence, 2016, v. 10, p. 223, doi. 10.2147/PPA.S99895
By:
- Huber, Carola A.;
- Brändle, Michael;
- Rapold, Roland;
- Reich, Oliver;
- Rosemann, Thomas
Publication type:
Article
Metformin Treatment Decreases mTOR mRNA Level in MCF-7 Breast Cancer Cells.
Published in:
Ibnosina Journal of Medicine & Biomedical Sciences, 2016, v. 8, n. 4, p. 99, doi. 10.4103/1947-489X.210230
By:
- Alalem, Mohamed;
- Ray, Alpana;
- Ray, Bimal K.
Publication type:
Article
SAVOR-TIMI to SUSTAIN-6: a critical comparison of cardiovascular outcome trials of antidiabetic drugs.
Published in:
Expert Review of Clinical Pharmacology, 2017, v. 10, n. 4, p. 429, doi. 10.1080/17512433.2017.1287562
By:
- Singh, Awadhesh Kumar;
- Singh, Ritu
Publication type:
Article
Cardiovascular Safety of New Drugs for Diabetes: Getting the Balance Right?
Published in:
Pharmaceutical Medicine, 2014, v. 28, n. 3, p. 109, doi. 10.1007/s40290-014-0053-7
By:
- Krentz, Andrew;
- Hompesch, Marcus
Publication type:
Article
Metformin and other antidiabetic agents in renal failure patients.
Published in:
Kidney International, 2015, v. 87, n. 2, p. 308, doi. 10.1038/ki.2014.19
By:
- Lalau, Jean-Daniel;
- Arnouts, Paul;
- Sharif, Adnan;
- De Broe, Marc E
Publication type:
Article
Effectiveness and safety of bifidobacteria and berberine in people with hyperglycemia: study protocol for a randomized controlled trial.
Published in:
2018
By:
- Ming, Jie;
- Xu, Shaoyong;
- Liu, Chun;
- Liu, Xiangyang;
- Jia, Aihua;
- Ji, Qiuhe
Publication type:
journal article
Influence of metformin intake on the risk of bladder cancer in type 2 diabetes patients.
Published in:
British Journal of Clinical Pharmacology, 2015, v. 80, n. 6, p. 1464, doi. 10.1111/bcp.12740
By:
- Goossens, Maria E.;
- Buntinx, Frank;
- Zeegers, Maurice P.;
- Driessen, J.H.M.;
- De Bruin, Marie L.;
- De Vries, Frank
Publication type:
Article
Hypoglycemic effects of an aqueous extract of Bauhinia forficata on the salivary glands of diabetic mice.
Published in:
Pakistan Journal of Pharmaceutical Sciences, 2012, v. 25, n. 3, p. 493
By:
- Curcio, Sergio Augusto Fudaba;
- Stefan, Luciana Francine Bocchi;
- Randi, Bruno Azevedo;
- Dias, Marco Antonio;
- Silva, Rodrigo Eduardo da;
- Caldeira, Eduardo José
Publication type:
Article
S6 Kinase Inhibits Intrinsic Axon Regeneration Capacity via AMP Kinase in Caenorhabditis elegans.
Published in:
Journal of Neuroscience, 2014, v. 34, n. 3, p. 758, doi. 10.1523/JNEUROSCI.2886-13.2014
By:
- Hubert, Thomas;
- Zilu Wu;
- Chisholm, Andrew D.;
- Yishi Jin
Publication type:
Article
A randomized controlled clinical trial of vildagliptin plus metformin combination therapy in patients with type II diabetes mellitus.
Published in:
Experimental & Therapeutic Medicine, 2014, v. 7, n. 4, p. 799, doi. 10.3892/etm.2014.1545
By:
- YONG SU;
- YA-LI SU;
- LI-FANG LV;
- LI-MIN WANG;
- QUAN-ZHONG LI;
- ZHI-GANG ZHAO
Publication type:
Article
Efficacy of alogliptin in preventing non-alcoholic fatty liver disease progression in patients with type 2 diabetes.
Published in:
Biomedical Reports, 2016, v. 4, n. 2, p. 183, doi. 10.3892/br.2016.569
By:
- TSUYOSHI MASHITANI;
- RYUICHI NOGUCHI;
- YASUSHI OKURA;
- TADASHI NAMISAKI;
- AKIRA MITORO;
- HITOSHI ISHII;
- TOSHIYA NAKATANI;
- EIRYO KIKUCHI;
- HIROTO MORIYASU;
- MASAMI MATSUMOTO;
- SHINYA SATO;
- TATSUICHI AN;
- HIROSHI MORITA;
- SIGEYUKI AIZAWA;
- YASUNORI TOKUOKA;
- MASATOSHI ISHIKAWA;
- YOSHINOBU MATSUMURA;
- HIROMASA OHIRA;
- ATSUKO KOGURE;
- KAZUHIRO NOGUCHI
Publication type:
Article
Therapeutic potential of cyanobacteria against streptozotocin-induced diabetic rats.
Published in:
3 Biotech, 2016, v. 6, n. 1, p. 1, doi. 10.1007/s13205-016-0411-0
By:
- Pandurangan, Muthuraman;
- Doo Hwan Kim
Publication type:
Article
Diazole and triazole derivatives of castor oil extract: synthesis, hypoglycemic effect, antioxidant potential and antimicrobial activity.
Published in:
Grasas y Aceites, 2020, v. 71, n. 4, p. 1, doi. 10.3989/gya.0342191
By:
- Brahimi, F. Taieb;
- Belkhadem, F.;
- Trari, B.;
- Othman, A. A.
Publication type:
Article