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Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects.
Published in:
Diabetes, Obesity & Metabolism, 2023, v. 25, n. 3, p. 856, doi. 10.1111/dom.14937
By:
- Asker, Mohammed;
- Krieger, Jean‐Philippe;
- Liles, Amber;
- Tinsley, Ian C.;
- Borner, Tito;
- Maric, Ivana;
- Doebley, Sarah;
- Furst, C. Daniel;
- Börchers, Stina;
- Longo, Francesco;
- Bhat, Yashaswini R.;
- De Jonghe, Bart C.;
- Hayes, Matthew R.;
- Doyle, Robert P.;
- Skibicka, Karolina P.
Publication type:
Article
A second‐generation glucagon‐like peptide‐1 receptor agonist mitigates vomiting and anorexia while retaining glucoregulatory potency in lean diabetic and emetic mammalian models.
Published in:
Diabetes, Obesity & Metabolism, 2020, v. 22, n. 10, p. 1729, doi. 10.1111/dom.14089
By:
- Borner, Tito;
- Shaulson, Evan D.;
- Tinsley, Ian C.;
- Stein, Lauren M.;
- Horn, Charles C.;
- Hayes, Matthew R.;
- Doyle, Robert P.;
- De Jonghe, Bart C.
Publication type:
Article
Cover Image, Volume 20, Issue 5.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 5, p. i, doi. 10.1111/dom.13540
By:
- Mietlicki‐Baase, Elizabeth G.;
- Liberini, Claudia G.;
- Reiner, David J.;
- Koch‐Laskowski, Kieran;
- McGrath, Lauren E.;
- Lhamo, Rinzin;
- Stein, Lauren M.;
- Hayes, Matthew R.;
- Workinger, Jayme L.;
- Bonaccorso, Ron L.;
- Doyle, Robert P.;
- Borner, Tito;
- De Jonghe, Bart C.;
- Holz, George G.;
- Roth, Christian L.
Publication type:
Article
Cover Image, Volume 20, Issue 5.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 5, p. i, doi. 10.1111/dom.13314
By:
- Mietlicki‐Baase, Elizabeth G.;
- Liberini, Claudia G.;
- Workinger, Jayme L.;
- Bonaccorso, Ron L.;
- Borner, Tito;
- Reiner, David J.;
- Koch‐Laskowski, Kieran;
- McGrath, Lauren E.;
- Lhamo, Rinzin;
- Stein, Lauren M.;
- De Jonghe, Bart C.;
- Holz, George G.;
- Roth, Christian L.;
- Doyle, Robert P.;
- Hayes, Matthew R.
Publication type:
Article
A vitamin B12 conjugate of exendin‐4 improves glucose tolerance without associated nausea or hypophagia in rodents.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 5, p. 1223, doi. 10.1111/dom.13222
By:
- Mietlicki‐Baase, Elizabeth G.;
- Liberini, Claudia G.;
- Reiner, David J.;
- Koch‐Laskowski, Kieran;
- McGrath, Lauren E.;
- Lhamo, Rinzin;
- Stein, Lauren M.;
- Hayes, Matthew R.;
- Workinger, Jayme L.;
- Bonaccorso, Ron L.;
- Doyle, Robert P.;
- Borner, Tito;
- De Jonghe, Bart C.;
- Holz, George G.;
- Roth, Christian L.
Publication type:
Article
Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41407-2
By:
- Salimando, Gregory J.;
- Tremblay, Sébastien;
- Kimmey, Blake A.;
- Li, Jia;
- Rogers, Sophie A.;
- Wojick, Jessica A.;
- McCall, Nora M.;
- Wooldridge, Lisa M.;
- Rodrigues, Amrith;
- Borner, Tito;
- Gardiner, Kristin L.;
- Jayakar, Selwyn S.;
- Singeç, Ilyas;
- Woolf, Clifford J.;
- Hayes, Matthew R.;
- De Jonghe, Bart C.;
- Bennett, F. Christian;
- Bennett, Mariko L.;
- Blendy, Julie A.;
- Platt, Michael L.
Publication type:
Article
GABA neurons in the nucleus tractus solitarius express GLP-1 receptors and mediate anorectic effects of liraglutide in rats.
Published in:
Science Translational Medicine, 2020, v. 12, n. 533, p. 1, doi. 10.1126/scitranslmed.aay8071
By:
- Fortin, Samantha M.;
- Lipsky, Rachele K.;
- Lhamo, Rinzin;
- Chen, Jack;
- Kim, Eun;
- Borner, Tito;
- Schmidt, Heath D.;
- Hayes, Matthew R.
Publication type:
Article
Olanzapine Administration Reduces Chemotherapy-Induced Nausea Behavior in Rats.
Published in:
Biological Research for Nursing, 2021, v. 23, n. 4, p. 584, doi. 10.1177/10998004211000443
By:
- Jaime-Lara, Rosario B.;
- Borner, Tito;
- Holland, Ruby A.;
- Shaulson, Evan;
- Brooks, Brianna;
- De Jonghe, Bart C.
Publication type:
Article
Glucagon‐like peptide‐1 in diabetes care: Can glycaemic control be achieved without nausea and vomiting?
Published in:
British Journal of Pharmacology, 2022, v. 179, n. 4, p. 542, doi. 10.1111/bph.15647
By:
- Borner, Tito;
- Tinsley, Ian C.;
- Doyle, Robert P.;
- Hayes, Matthew R.;
- De Jonghe, Bart C.
Publication type:
Article
Anorexia-cachexia syndrome in hepatoma tumour-bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC-1/GDF15.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2017, v. 8, n. 3, p. 417, doi. 10.1002/jcsm.12169
By:
- Borner, Tito;
- Arnold, Myrtha;
- Ruud, Johan;
- Breit, Samuel N.;
- Langhans, Wolfgang;
- Lutz, Thomas A.;
- Blomqvist, Anders;
- Riediger, Thomas
Publication type:
Article
Novel Insights into the Physiology of Nutrient Sensing and Gut-Brain Communication in Surgical and Experimental Obesity Therapy.
Published in:
Obesity Surgery, 2023, v. 33, n. 9, p. 2906, doi. 10.1007/s11695-023-06739-4
By:
- Frick, Lukas D.;
- Hankir, Mohammed K.;
- Borner, Tito;
- Malagola, Ermanno;
- File, Bálint;
- Gero, Daniel
Publication type:
Article
GPR-160 Receptor Signaling in the Dorsal Vagal Complex of Male Rats Modulates Meal Microstructure and CART-Mediated Hypophagia.
Published in:
Nutrients, 2023, v. 15, n. 10, p. 2268, doi. 10.3390/nu15102268
By:
- Sanchez-Navarro, Marcos J.;
- Borner, Tito;
- Reiner, Benjamin C.;
- Crist, Richard C.;
- Samson, Willis K.;
- Yosten, Gina L. C.;
- Stein, Lauren;
- Hayes, Matthew R.
Publication type:
Article
GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior.
Published in:
Diabetes, 2022, v. 71, n. 7, p. 1410, doi. 10.2337/db21-0848
By:
- Samms, Ricardo J.;
- Cosgrove, Richard;
- Snider, Brandy M.;
- Furber, Ellen C.;
- Droz, Brian A.;
- Briere, Daniel A.;
- Dunbar, James;
- Dogra, Mridula;
- Alsina-Fernandez, Jorge;
- Borner, Tito;
- De Jonghe, Bart C.;
- Hayes, Matthew R.;
- Coskun, Tamer;
- Sloop, Kyle W.;
- Emmerson, Paul J.;
- Ai, Minrong
Publication type:
Article
GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist-Induced Nausea and Emesis in Preclinical Models.
Published in:
2021
By:
- Borner, Tito;
- Geisler, Caroline E.;
- Fortin, Samantha M.;
- Cosgrove, Richard;
- Alsina-Fernandez, Jorge;
- Dogra, Mridula;
- Doebley, Sarah;
- Sanchez-Navarro, Marcos J.;
- Leon, Rosa M.;
- Gaisinsky, Jane;
- White, Arianna;
- Bamezai, Ankur;
- Ghidewon, Misgana Y.;
- Grill, Harvey J.;
- Crist, Richard C.;
- Reiner, Benjamin C.;
- Ai, Minrong;
- Samms, Ricardo J.;
- De Jonghe, Bart C.;
- Hayes, Matthew R.
Publication type:
journal article
The Role of GIP in the Regulation of GLP-1 Satiety and Nausea.
Published in:
2021
By:
- Hayes, Matthew R.;
- Borner, Tito;
- De Jonghe, Bart C.
Publication type:
journal article

Found: 15