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Title

Learning From Glycosuria.

Authors

Ferrannini, Ele

Abstract

The author comments on the study "SGLT2 Deletion Improves Glucose Homeostasis and Preserves Pancreatic β-Cell Function." She discusses the functions of the SGLT-2, a member of the sodium glucose transporter (SGLT) family of transmembrane proteins. She explores the physiological effects of deleting SGLT-2. She addresses the inability to achieve the complete blockade of renal glucose reabsorption with selective SGLT-2 inhibition.

Subjects

GLYCOSURIA; GLUCOSE; PANCREATIC beta cells; PROTEINS; HOMEOSTASIS

Publication

Diabetes, 2011, Vol 60, Issue 3, p695

ISSN

0012-1797

Publication type

Academic Journal

DOI

10.2337/db10-1667

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