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Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study.
Published in:
2019
By:
- De Silva, N. Maneka G.;
- Borges, Maria Carolina;
- Hingorani, Aroon D.;
- Engmann, Jorgen;
- Shah, Tina;
- Xiaoshuai Zhang;
- Jian'an Luan;
- Langenberg, Claudia;
- Wong, Andrew;
- Kuh, Diana;
- Chambers, John C.;
- Weihua Zhang;
- Jarvelin, Marjo-Ritta;
- Sebert, Sylvain;
- Auvinen, Juha;
- Gaunt, Tom R.;
- Lawlor, Deborah A.;
- Zhang, Xiaoshuai;
- Luan, Jian'an;
- Zhang, Weihua
Publication type:
journal article
Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-35563-0
By:
- Kentistou, Katherine A.;
- Luan, Jian'an;
- Wittemans, Laura B. L.;
- Hambly, Catherine;
- Klaric, Lucija;
- Kutalik, Zoltán;
- Speakman, John R.;
- Wareham, Nicholas J.;
- Kendall, Timothy J.;
- Langenberg, Claudia;
- Wilson, James F.;
- Joshi, Peter K.;
- Morton, Nicholas M.
Publication type:
Article
Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 4, p. 1065, doi. 10.1210/clinem/dgab877
By:
- Koprulu, Mine;
- Zhao, Yajie;
- Wheeler, Eleanor;
- Dong, Liang;
- Rocha, Nuno;
- Li, Chen;
- Griffin, John D.;
- Patel, Satish;
- de Streek, Marcel Van;
- Glastonbury, Craig A.;
- Stewart, Isobel D.;
- Day, Felix R.;
- Luan, Jian’an;
- Bowker, Nicholas;
- Wittemans, Laura B. L.;
- Kerrison, Nicola D.;
- Cai, Lina;
- Lucarelli, Debora M. E.;
- Barroso, Inês;
- McCarthy, Mark I.
Publication type:
Article
Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans.
Published in:
2010
By:
- Schoenmakers, Erik;
- Agostini, Maura;
- Mitchell, Catherine;
- Schoenmakers, Nadia;
- Papp, Laura;
- Rajanayagam, Odelia;
- Padidela, Raja;
- Ceron-Gutierrez, Lourdes;
- Doffinger, Rainer;
- Prevosto, Claudia;
- Luan, Jian'an;
- Montano, Sergio;
- Jun Lu;
- Castanet, Mireille;
- Clemons, Nick;
- Groeneveld, Matthijs;
- Castets, Perrine;
- Karbaschi, Mahsa;
- Aitken, Sri;
- Dixon, Adrian
Publication type:
journal article
Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study.
Published in:
Scientific Data, 2020, v. 7, n. 1, p. 1, doi. 10.1038/s41597-020-00716-7
By:
- Cai, Lina;
- Wheeler, Eleanor;
- Kerrison, Nicola D.;
- Luan, Jian'an;
- Deloukas, Panos;
- Franks, Paul W.;
- Amiano, Pilar;
- Ardanaz, Eva;
- Bonet, Catalina;
- Fagherazzi, Guy;
- Groop, Leif C.;
- Kaaks, Rudolf;
- Huerta, José María;
- Masala, Giovanna;
- Nilsson, Peter M.;
- Overvad, Kim;
- Pala, Valeria;
- Panico, Salvatore;
- Rodriguez-Barranco, Miguel;
- Rolandsson, Olov
Publication type:
Article
Synergistic insights into human health from aptamer- and antibody-based proteomic profiling.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27164-0
By:
- Pietzner, Maik;
- Wheeler, Eleanor;
- Carrasco-Zanini, Julia;
- Kerrison, Nicola D.;
- Oerton, Erin;
- Koprulu, Mine;
- Luan, Jian'an;
- Hingorani, Aroon D.;
- Williams, Steve A.;
- Wareham, Nicholas J.;
- Langenberg, Claudia
Publication type:
Article
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Published in:
Nature Genetics, 2013, v. 45, n. 5, p. 501, doi. 10.1038/ng.2606
By:
- Berndt, Sonja I;
- Gustafsson, Stefan;
- Mägi, Reedik;
- Ganna, Andrea;
- Wheeler, Eleanor;
- Feitosa, Mary F;
- Justice, Anne E;
- Monda, Keri L;
- Croteau-Chonka, Damien C;
- Day, Felix R;
- Esko, Tõnu;
- Fall, Tove;
- Ferreira, Teresa;
- Gentilini, Davide;
- Jackson, Anne U;
- Luan, Jian'an;
- Randall, Joshua C;
- Vedantam, Sailaja;
- Willer, Cristen J;
- Winkler, Thomas W
Publication type:
Article
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Published in:
Nature Genetics, 2012, v. 44, n. 9, p. 981, doi. 10.1038/ng.2383
By:
- Morris, Andrew P;
- Voight, Benjamin F;
- Teslovich, Tanya M;
- Ferreira, Teresa;
- Segrè, Ayellet V;
- Steinthorsdottir, Valgerdur;
- Strawbridge, Rona J;
- Khan, Hassan;
- Grallert, Harald;
- Mahajan, Anubha;
- Prokopenko, Inga;
- Kang, Hyun Min;
- Dina, Christian;
- Esko, Tonu;
- Fraser, Ross M;
- Kanoni, Stavroula;
- Kumar, Ashish;
- Lagou, Vasiliki;
- Langenberg, Claudia;
- Luan, Jian'an
Publication type:
Article
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
Published in:
Nature Genetics, 2012, v. 44, n. 9, p. 991, doi. 10.1038/ng.2385
By:
- Scott, Robert A;
- Lagou, Vasiliki;
- Welch, Ryan P;
- Wheeler, Eleanor;
- Montasser, May E;
- Luan, Jian'an;
- Mägi, Reedik;
- Strawbridge, Rona J;
- Rehnberg, Emil;
- Gustafsson, Stefan;
- Kanoni, Stavroula;
- Rasmussen-Torvik, Laura J;
- Yengo, Loïc;
- Lecoeur, Cecile;
- Shungin, Dmitry;
- Sanna, Serena;
- Sidore, Carlo;
- Johnson, Paul C D;
- Jukema, J Wouter;
- Johnson, Toby
Publication type:
Article
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
Published in:
2011
By:
- Heid, Iris M;
- Jackson, Anne U;
- Randall, Joshua C;
- Winkler, Thomas W;
- Qi, Lu;
- Steinthorsdottir, Valgerdur;
- Thorleifsson, Gudmar;
- Zillikens, M Carola;
- Speliotes, Elizabeth K;
- Mägi, Reedik;
- Workalemahu, Tsegaselassie;
- White, Charles C;
- Bouatia-Naji, Nabila;
- Harris, Tamara B;
- Berndt, Sonja I;
- Ingelsson, Erik;
- Willer, Cristen J;
- Weedon, Michael N;
- Luan, Jian'an;
- Vedantam, Sailaja
Publication type:
Correction Notice
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Published in:
Nature Genetics, 2011, v. 43, n. 11, p. 1131, doi. 10.1038/ng.970
By:
- Chambers, John C;
- Zhang, Weihua;
- Sehmi, Joban;
- Li, Xinzhong;
- Wass, Mark N;
- Van der Harst, Pim;
- Holm, Hilma;
- Sanna, Serena;
- Kavousi, Maryam;
- Baumeister, Sebastian E;
- Coin, Lachlan J;
- Deng, Guohong;
- Gieger, Christian;
- Heard-Costa, Nancy L;
- Hottenga, Jouke-Jan;
- Kühnel, Brigitte;
- Kumar, Vinod;
- Lagou, Vasiliki;
- Liang, Liming;
- Luan, Jian'an
Publication type:
Article
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
Published in:
Nature Genetics, 2011, v. 43, n. 8, p. 753, doi. 10.1038/ng.866
By:
- Kilpelainen, Tuomas O.;
- Carola Zillikens, M.;
- Stančakova, Alena;
- Finucane, Francis M.;
- Ried, Janina S.;
- Langenberg, Claudia;
- Weihua Zhang;
- Beckmann, Jacques S.;
- Jian’an Luan;
- Vandenput, Liesbeth;
- Styrkarsdottir, Unnur;
- Yanhua Zhou;
- Smith, Albert Vernon;
- Jing-Hua Zhao;
- Amin, Najaf;
- Vedantam, Sailaja;
- So-Youn Shin;
- Haritunians, Talin;
- Mao Fu;
- Feitosa, Mary F.
Publication type:
Article
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
Published in:
Nature Genetics, 2010, v. 42, n. 11, p. 949, doi. 10.1038/ng.685
By:
- Heid, Iris M.;
- Jackson, Anne U.;
- Randall, Joshua C.;
- Winkler, Thomas W.;
- Lu Qi;
- Steinthorsdottir, Valgerdur;
- Thorleifsson, Gudmar;
- Zillikens, M. Carola;
- Speliotes, Elizabeth K.;
- Mägi, Reedik;
- Workalemahu, Tsegaselassie;
- White, Charles C.;
- Bouatia-Naji, Nabila;
- Harris, Tamara B.;
- Berndt, Sonja I.;
- Ingelsson, Erik;
- Willer, Cristen J.;
- Weedon, Michael N.;
- Luan, Jian'an;
- Vedantam, Sailaja
Publication type:
Article
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
Published in:
Nature Genetics, 2010, v. 42, n. 11, p. 937, doi. 10.1038/ng.686
By:
- Speliotes, Elizabeth K.;
- Willer, Cristen J.;
- Berndt, Sonja I.;
- Monda, Keri L.;
- Thorleifsson, Gudmar;
- Jackson, Anne U.;
- Allen, Hana Lango;
- Lindgren, Cecilia M.;
- Luan, Jian'an;
- Mägi, Reedik;
- Randall, Joshua C.;
- Vedantam, Sailaja;
- Winkler, Thomas W.;
- Lu Qi;
- Workalemahu, Tsegaselassie;
- Heid, Iris M.;
- Steinthorsdottir, Valgerdur;
- Stringham, Heather M.;
- Weedon, Michael N.;
- Wheeler, Eleanor
Publication type:
Article
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
Published in:
Nature Genetics, 2010, v. 42, n. 2, p. 142, doi. 10.1038/ng.521
By:
- Saxena, Richa;
- Hivert, Marie-France;
- Langenberg, Claudia;
- Tanaka, Toshiko;
- Pankow, James S.;
- Vollenweider, Peter;
- Lyssenko, Valeriya;
- Bouatia-Naji, Nabila;
- Dupuis, Josée;
- Jackson, Anne U.;
- Linda Kao, W. H.;
- Man Li;
- Glazer, Nicole L.;
- Manning, Alisa K.;
- Jian'an Luan;
- Stringham, Heather M.;
- Prokopenko, Inga;
- Johnson, Toby;
- Grarup, Niels;
- Boesgaard, Trine W.
Publication type:
Article
Genetic variation in LIN28B is associated with the timing of puberty.
Published in:
Nature Genetics, 2009, v. 41, n. 6, p. 729, doi. 10.1038/ng.382
By:
- Ong, Ken K.;
- Elks, Cathy E.;
- Shengxu Li;
- Jing Hua Zhao;
- Jian'an Luan;
- Andersen, Lars B.;
- Bingham, Sheila A.;
- Brage, Soren;
- Smith, George Davey;
- Ekelund, Ulf;
- Gillson, Christopher J.;
- Glaser, Beate;
- Golding, Jean;
- Hardy, Rebecca;
- Kay-Tee Khaw;
- Kuh, Diana;
- Luben, Robert;
- Marcus, Michele;
- McGeehin, Michael A.;
- Ness, Andrew R.
Publication type:
Article
Digenic inheritance of severe insulin resistance in a human pedigree.
Published in:
Nature Genetics, 2002, v. 31, n. 4, p. 379, doi. 10.1038/ng926
By:
- Savage, David B.;
- Agostini, Maura;
- Barroso, Inês;
- Gurnell, Mark;
- Luan, Jian'an;
- Meirhaeghe, Aline;
- Harding, Anne-Helen;
- Ihrke, Gudrun;
- Rajanayagam, Odelia;
- Soos, Maria A.;
- George, Stella;
- Berger, Dirk;
- Thomas, E. Louise;
- Bell, Jimmy D.;
- Meeran, Karim;
- Ross, Richard J.;
- Vidal-Puig, Antonio;
- Wareham, Nicholas J.;
- O'Rahilly, Stephen;
- Chatterjee, V. Krishna K.
Publication type:
Article
Features of effective staff training programmes within school-based interventions targeting student activity behaviour: a systematic review and meta-analysis.
Published in:
International Journal of Behavioral Nutrition & Physical Activity, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12966-022-01361-6
By:
- Ryan, Mairead;
- Alliott, Olivia;
- Ikeda, Erika;
- Luan, Jian'an;
- Hofmann, Riikka;
- van Sluijs, Esther
Publication type:
Article
Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions.
Published in:
PLoS Genetics, 2017, v. 13, n. 6, p. 1, doi. 10.1371/journal.pgen.1006812
By:
- Shungin, Dmitry;
- Deng, Wei Q.;
- Varga, Tibor V.;
- Luan, Jian'an;
- Mihailov, Evelin;
- Metspalu, Andres;
- null, null;
- Morris, Andrew P.;
- Forouhi, Nita G.;
- Lindgren, Cecilia;
- Magnusson, Patrik K. E.;
- Pedersen, Nancy L.;
- Hallmans, Göran;
- Chu, Audrey Y.;
- Justice, Anne E.;
- Graff, Mariaelisa;
- Winkler, Thomas W.;
- Rose, Lynda M.;
- Langenberg, Claudia;
- Cupples, L. Adrienne
Publication type:
Article
Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.
Published in:
Diabetologia, 2023, v. 66, n. 7, p. 1260, doi. 10.1007/s00125-023-05922-7
By:
- Li, Josephine H.;
- Brenner, Laura N.;
- Kaur, Varinderpal;
- Figueroa, Katherine;
- Schroeder, Philip;
- Huerta-Chagoya, Alicia;
- MAGIC Investigators;
- Chen, Ji;
- Spracklen, Cassandra N.;
- Marenne, Gaëlle;
- Varshney, Arushi;
- Corbin, Laura J.;
- Luan, Jian'an;
- Willems, Sara M.;
- Wu, Ying;
- Zhang, Xiaoshuai;
- Horikoshi, Momoko;
- Boutin, Thibaud S.;
- Mägi, Reedik;
- Waage, Johannes
Publication type:
Article
Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46639-4
By:
- Thériault, Sébastien;
- Li, Zhonglin;
- Abner, Erik;
- Luan, Jian'an;
- Manikpurage, Hasanga D.;
- Houessou, Ursula;
- Zamani, Pardis;
- Briend, Mewen;
- Boudreau, Dominique K.;
- Gaudreault, Nathalie;
- Frenette, Lily;
- Argaud, Déborah;
- Dahmene, Manel;
- Dagenais, François;
- Clavel, Marie-Annick;
- Pibarot, Philippe;
- Arsenault, Benoit J.;
- Boekholdt, S. Matthijs;
- Wareham, Nicholas J.;
- Esko, Tõnu
Publication type:
Article
A Latent Variable Partial Least Squares Path Modeling Approach to Regional Association and Polygenic Effect with Applications to a Human Obesity Study.
Published in:
PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031927
By:
- Fuzhong Xue;
- Shengxu Li;
- Jian'an Luan;
- Zhongshang Yuan;
- Luben, Robert N.;
- Khaw, Kay-Tee;
- Wareham, Nicholas J.;
- Loos, Ruth J. F.;
- Jing Hua Zhao
Publication type:
Article
Does physical activity energy expenditure explain the between-individual variation in plasma leptin concentrations after adjusting for differences in body composition?
Published in:
2003
By:
- Franks, Paul W;
- Farooqi, I Sadaf;
- Luan, Jian'an;
- Wong, Man-Yu;
- Halsall, Ian;
- O'Rahilly, Stephen;
- Wareham, Nicholas J
Publication type:
journal article
The Effect of the Gly16Arg Polymorphism of the β<sub>2</sub>-Adrenergic Receptor Gene on Plasma Free Fatty Acid Levels Is Modulated by Physical Activity.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 12, p. 5881, doi. 10.1210/jc.86.12.5881
By:
- MEIRHAEGHE, ALINE;
- LUAN, JIAN’AN;
- SELBERG-FRANKS, PAUL;
- HENNINGS, SUSIE;
- MITCHELL, JO;
- HALSALL, DAVID;
- O’RAHILLY, STEPHEN;
- WAREHAM, NICHOLAS J.
Publication type:
Article
Compensatory mammary growth following protein restriction during pregnancy and lactation increases early-onset mammary tumor incidence in rats.
Published in:
Carcinogenesis, 2007, v. 28, n. 3, p. 545
By:
- D.S. Fernandez-Twinn;
- B.A. Gusterson;
- Jian'an Luan
Publication type:
Article
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Published in:
Nature Communications, 2017, v. 8, n. 7, p. 1, doi. 10.1038/s41467-017-00031-7
By:
- Zillikens, M. Carola;
- Demissie, Serkalem;
- Yi-Hsiang Hsu;
- Yerges-Armstrong, Laura M.;
- Wen-Chi Chou;
- Stolk, Lisette;
- Livshits, Gregory;
- Broer, Linda;
- Johnson, Toby;
- Koller, Daniel L.;
- Kutalik, Zoltán;
- Luan, Jian’an;
- Malkin, Ida;
- Ried, Janina S.;
- Smith, Albert V.;
- Thorleifsson, Gudmar;
- Vandenput, Liesbeth;
- Jing Hua Zhao;
- Weihua Zhang;
- Aghdassi, Ali
Publication type:
Article
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
Published in:
Nature Communications, 2014, v. 5, n. 10, p. 4926, doi. 10.1038/ncomms5926
By:
- Benyamin, Beben;
- Esko, Tonu;
- Ried, Janina S.;
- Radhakrishnan, Aparna;
- Vermeulen, Sita H.;
- Traglia, Michela;
- Gögele, Martin;
- Anderson, Denise;
- Broer, Linda;
- Podmore, Clara;
- Luan, Jian'an;
- Kutalik, Zoltan;
- Sanna, Serena;
- van der Meer, Peter;
- Tanaka, Toshiko;
- Wang, Fudi;
- Westra, Harm-Jan;
- Franke, Lude;
- Mihailov, Evelin;
- Milani, Lili
Publication type:
Article
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
Published in:
Science Translational Medicine, 2016, v. 8, n. 341, p. 1, doi. 10.1126/scitranslmed.aad3744
By:
- Scott, Robert A.;
- Freitag, Daniel F.;
- Li Li;
- Chu, Audrey Y.;
- Surendran, Praveen;
- Young, Robin;
- Grarup, Niels;
- Stancáková, Alena;
- Yuning Chen;
- Varga, Tibor V.;
- Yaghootkar, Hanieh;
- Jian’an Luan;
- Jing Hua Zhao;
- Willems, Sara M.;
- Wessel, Jennifer;
- Shuai Wang;
- Maruthur, Nisa;
- Michailidou, Kyriaki;
- Pirie, Ailith;
- van der Lee, Sven J.
Publication type:
Article
Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 14, p. 2791, doi. 10.1093/hmg/ddx174
By:
- Mullin, Benjamin H.;
- Jing Hua Zhao;
- Brown, Suzanne J.;
- Perry, John R. B.;
- Luan, Jian'an;
- Hou-Feng Zheng;
- Langenberg, Claudia;
- Dudbridge, Frank;
- Scott, Robert;
- Wareham, Nick J.;
- Spector, Tim D.;
- Richards, J. Brent;
- Walsh, John P.;
- Wilson, Scott G.
Publication type:
Article
Testing the role of predicted gene knockouts in human anthropometric trait variation.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 10, p. 2082, doi. 10.1093/hmg/ddw055
By:
- Lessard, Samuel;
- Manning, Alisa K.;
- Cécile Low-Kam;
- Auer, Paul L.;
- Giri, Ayush;
- Graff, Mariaelisa;
- Schurmann, Claudia;
- Yaghootkar, Hanieh;
- Luan, Jian'an;
- Esko, Tonu;
- Karaderi, Tugce;
- Bottinger, Erwin P.;
- Yingchang Lu;
- Carlson, Chris;
- Caulfield, Mark;
- Dubé, Marie-Pierre;
- Jackson, Rebecca D.;
- Kooperberg, Charles;
- McKnight, Barbara;
- Mongrain, Ian
Publication type:
Article
Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.
Published in:
2018
By:
- Lotta, Luca A.;
- Wittemans, Laura B. L.;
- Zuber, Verena;
- Stewart, Isobel D.;
- Sharp, Stephen J.;
- Luan, Jian'an;
- Day, Felix R.;
- Li, Chen;
- Bowker, Nicholas;
- Cai, Lina;
- De Lucia Rolfe, Emanuella;
- Khaw, Kay-Tee;
- Perry, John R. B.;
- O'Rahilly, Stephen;
- Scott, Robert A.;
- Savage, David B.;
- Burgess, Stephen;
- Wareham, Nicholas J.;
- Langenberg, Claudia
Publication type:
journal article
Population-Specific Risk of Type 2 Diabetes Conferred by HNF4A P2 Promoter Variants.
Published in:
Diabetes, 2008, v. 57, n. 11, p. 3161, doi. 10.2337/db08-0719
By:
- Barroso, Inês;
- Luan, Jian'an;
- Wheeler, Eleanor;
- Whittaker, Pamela;
- Wasson, Jon;
- Zeggini, Eleftheria;
- Weedon, Michael N.;
- Hunt, Sarah;
- Venkatesh, Ranganath;
- Frayling, Timothy M.;
- Delgado, Marcos;
- Neuman, Rosalind J.;
- Zhao, Jinghua;
- Sherva, Richard;
- Glaser, Benjamin;
- Walker, Mark;
- Hitman, Graham;
- McCarthy, Mark I.;
- Hattersley, Andrew T.;
- Permutt, M. Alan
Publication type:
Article
Baseline serum 25-hydroxy vitamin d is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000.
Published in:
2008
By:
- Forouhi NG;
- Luan J;
- Cooper A;
- Boucher BJ;
- Wareham NJ;
- Forouhi, Nita G;
- Luan, Jian'an;
- Cooper, Andrew;
- Boucher, Barbara J;
- Wareham, Nicholas J
Publication type:
journal article
Baseline Serum 25-Hydroxy Vitamin D Is Predictive of Future Glycemic Status and Insulin Resistance.
Published in:
Diabetes, 2008, v. 57, n. 10, p. 2619, doi. 10.2337/db08-0593
By:
- Forouhi, Nita G.;
- Luan, Jian'an;
- Cooper, Andrew;
- Boucher, Barbara J.;
- Wareham, Nicholas J.
Publication type:
Article
Retinol Binding Protein 4 (RBP4) Levels Are Associated with Markers of Lipid Metabolism and Insulin Resistance in a British Cohort.
Published in:
Diabetes, 2007, v. 56, p. A251
By:
- Bouatia-Naji, Nabila;
- Semple, Robert K.;
- Luan, Jian'an;
- Burling, Keith;
- Loos, Ruth J.;
- O'Rahilly, Stephen;
- Wareham, Nicholas J.
Publication type:
Article
Paradoxical Elevation of High-Molecular Weight Adiponectin in Acquired Extreme Insulin Resistance Due to Insulin Receptor Antibodies.
Published in:
Diabetes, 2007, v. 56, n. 6, p. 1712, doi. 10.2337/db06-1665
By:
- Semple, Robert K.;
- Halberg, Nils H.;
- Burling, Keith;
- Soos, Maria A.;
- Schraw, Todd;
- Luan, Jian'an;
- Cochran, Elaine K.;
- Dunger, David B.;
- Wareham, Nicholas J.;
- Scherer, Philipp E.;
- Gorden, Phillip;
- O'Rahilly, Stephen
Publication type:
Article
Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.
Published in:
2007
By:
- Mesa JL;
- Loos RJ;
- Franks PW;
- Ong KK;
- Luan J;
- O'rahilly S;
- Wareham NJ;
- Barroso I;
- Mesa, José L;
- Loos, Ruth J F;
- Franks, Paul W;
- Ong, Ken K;
- Luan, Jian'an;
- O'Rahilly, Stephen;
- Wareham, Nicholas J;
- Barroso, Inês
Publication type:
journal article
Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes.
Published in:
2007
By:
- Tan K;
- Kimber WA;
- Luan J;
- Soos MA;
- Semple RK;
- Wareham NJ;
- O'rahilly S;
- Barroso I;
- Tan, Karen;
- Kimber, Wendy A;
- Luan, Jian'an;
- Soos, Maria A;
- Semple, Robert K;
- Wareham, Nicholas J;
- O'Rahilly, Stephen;
- Barroso, Inês
Publication type:
journal article
Lamin A/C Polymorphisms, Type 2 Diabetes, and the Metabolic Syndrome.
Published in:
Diabetes, 2007, v. 56, n. 3, p. 884, doi. 10.2337/db06-1055
By:
- Mesa, José L.;
- Loos, Ruth J. F.;
- Franks, Paul W.;
- Ong, Ken K.;
- Luan, Jian'an;
- O'Rahilly, Stephen;
- Wareham, Nicholas J.;
- Barroso, Inês
Publication type:
Article
Analysis of Genetic Variation in Akt2/PKB-β in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes.
Published in:
Diabetes, 2007, v. 56, n. 3, p. 714, doi. 10.2337/db06-0921
By:
- Tan, Karen;
- Kimber, Wendy A.;
- Luan, Jian'an;
- Soos, Maria A.;
- Semple, Robert K.;
- Wareham, Nicholas J.;
- O'Rahilly, Stephen;
- Barroso, Inês
Publication type:
Article
INS VNTR class genotype and indexes of body size and obesity: population-based studies of 7,999 middle-aged men and women.
Published in:
2005
By:
- Sandhu, Manjinder S.;
- Heude, Barbara;
- Young, Elizabeth H.;
- Luben, Robert;
- Luan, Jian'an;
- Khaw, Kay-Tee;
- Todd;
- Wareham, Nicholas J.;
- Todd, John
Publication type:
journal article
Variation in the eNOS gene modifies the association between total energy expenditure and glucose intolerance.
Published in:
2005
By:
- Franks, Paul W.;
- Luan, Jian'an;
- Barroso, Inês;
- Brage, Søren;
- Sanchez, Jose Luis Gonzalez;
- Ekelund, Ulf;
- Ríos, Manuel Serrano;
- Schafer, Alan J.;
- O'Rahilly, Stephen;
- Wareham, Nicholas J.;
- Barroso, Inês;
- Brage, Søren;
- Gonzalez Sanchez, Jose Luis;
- Ríos, Manuel Serrano
Publication type:
journal article
Studies of the peptide YY and neuropeptide Y2 receptor genes in relation to human obesity and obesity-related traits.
Published in:
2004
By:
- Hung, Chiao-Chien Connie;
- Pirie, Fraser;
- Luan, Jian'an;
- Lank, Emma;
- Motala, Ayesha;
- Yeo, Giles S.H.;
- Keogh, Julia M.;
- Wareham, Nicholas J.;
- O'Rahilly, Stephen;
- Farooqi, I. Sadaf
Publication type:
journal article
Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes.
Published in:
2004
By:
- Laudes, Matthias;
- Barroso, Inˆes;
- Luan, Jian'an;
- Soos, Maria A.;
- Yeo, Giles;
- Meirhaeghe, Aline;
- Logie, Lisa;
- Vidal-Puig, Antonio;
- Schafer, Alan J.;
- Wareham, Nick J.;
- O'Rahilly, Stephen;
- Barroso, Inês
Publication type:
journal article
Association of polymorphisms in GPR10, the gene encoding the prolactin-releasing peptide receptor with blood pressure, but not obesity, in a U.K. Caucasian population.
Published in:
2003
By:
- Bhattacharyya, Sumit;
- Luan, Jian'an;
- Challis, Benjamin;
- Schmitz, Catherine;
- Clarkson, Paul;
- Franks, Paul W.;
- Middelberg, Rita;
- Keogh, Julia;
- Farooqi, I. Sadaf;
- Montague, Carl;
- Brennand, John;
- Wareham, Nicholas J.;
- O'Rahilly, Stephen
Publication type:
journal article
Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations.
Published in:
2003
By:
- Hung, Chiao-Chien Connie;
- Farooqi, I. Sadaf;
- Ong, Ken;
- Luan, Jian'an;
- Keogh, Julia M.;
- Pembrey, Marcus;
- Yeo, Giles S. H.;
- Dunger, David;
- Wareham, Nicholas J.;
- O'Rahilly, Stephen
Publication type:
journal article
Evidence for gene-nutrient interaction at the PPARgamma locus.
Published in:
2001
By:
- Luan, Jian'an;
- Browne, Paul O.;
- Harding, Anne-Helen;
- Halsall, David J.;
- O'Rahilly, Stephen;
- Chatterjee, V.K. Krishna;
- Wareham, Nicholas J.;
- Luan, J;
- Browne, P O;
- Harding, A H;
- Halsall, D J;
- O'Rahilly, S;
- Chatterjee, V K;
- Wareham, N J
Publication type:
journal article
The CART Gene and Human Obesity.
Published in:
Diabetes, 2000, v. 49, n. 5, p. 872, doi. 10.2337/diabetes.49.5.872
By:
- Challis, Benjamin G.;
- Yeo, Giles S.H.;
- Farooqi, I. Sadaf;
- Luan, Jian'an;
- Aminian, Shiva;
- Halsall, David J.;
- Keogh, Julia M.;
- Wareham, Nicholas J.;
- O'Rahilly, Stephen
Publication type:
Article
The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.
Published in:
2020
By:
- Zheng, Ju-Sheng;
- Luan, Jian'an;
- Sofianopoulou, Eleni;
- Sharp, Stephen J.;
- Day, Felix R.;
- Imamura, Fumiaki;
- Gundersen, Thomas E.;
- Lotta, Luca A.;
- Sluijs, Ivonne;
- Stewart, Isobel D.;
- Shah, Rupal L.;
- van der Schouw, Yvonne T.;
- Wheeler, Eleanor;
- Ardanaz, Eva;
- Boeing, Heiner;
- Dorronsoro, Miren;
- Dahm, Christina C.;
- Dimou, Niki;
- El-Fatouhi, Douae;
- Franks, Paul W.
Publication type:
journal article
Correction: Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action.
Published in:
2003
By:
- Barroso, Inês;
- Luan, Jian'an;
- Middelberg, Rita P. S;
- Harding, Anne-Helen;
- Jakes, Rupert W;
- Clayton, David;
- Schafer, Alan J;
- O'Rahilly, Stephen;
- Wareham, Nicholas J
Publication type:
Correction Notice

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