Works matching DE "TUMOR suppressor genes"

Results: 5000

Oxindole–Coumarin Hybrids With Broad‐Spectrum Anticancer Activity: Apoptosis Induction and Selective CA IX/XII Targeting.

Published in:

Drug Development Research, 2025, v. 86, n. 4, p. 1, doi. 10.1002/ddr.70116

By:

Abdelaal, Hend I.;
Mohamed, Abdalla R.;
Elnagar, Mohamed R.;
Giovannuzzi, Simone;
Fahim, Samar H.;
Abdel‐Aziz, Hatem A.;
Supuran, Claudiu T.;
Abou‐Seri, Sahar M.

Publication type:

Article

Gambogic acid suppresses osteosarcoma progression through upregulation of FOXO3a.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02776-w

By:

Hu, Yawei;
Wu, Jiawen;
Ye, Songqing;
Zhang, Hao;
Guo, Zengfeng;
Han, Xiaohong;
Zhou, Jianhua

Publication type:

Article

ADAM32 Oncogene in Hepatoblastoma Is Regulated by IGF2BP2.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1772, doi. 10.3390/cancers17111772

By:

Fukazawa, Takahiro;
Tanimoto, Keiji;
Kojima, Masato;
Kanawa, Masami;
Hirohashi, Nobuyuki;
Hiyama, Eiso

Publication type:

Article

The Interplay of SMAD4 and EMT in Oral Squamous Cell Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1761, doi. 10.3390/cancers17111761

By:

Mozalbat, Shiraz;
Nashef, Aysar;
Maalouf, Naseem;
Abdol-Elraziq, Murad;
El-naaj, Imad Abu;
Tadmor, Hagar;
Ghantous, Yasmin

Publication type:

Article

Integrating Aggressive-Variant Prostate Cancer-Associated Tumor Suppressor Gene Status with Clinical Variables to Refine Prognosis and Predict Androgen Receptor Pathway Inhibitor Response in Metastatic Hormone-Sensitive Setting.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5309, doi. 10.3390/ijms26115309

By:

Pedrani, Martino;
Salfi, Giuseppe;
Merler, Sara;
Testi, Irene;
Agrippina Clerici, Chiara Maria;
Pecoraro, Giovanna;
Castelo-Branco, Luis;
Turco, Fabio;
Tortola, Luigi;
Vogl, Ursula;
Gillessen, Silke;
Theurillat, Jean-Philippe;
Zilli, Thomas;
Mestre, Ricardo Pereira

Publication type:

Article

The Predictive Impact of HPV Genotypes, Tumor Suppressors and Local Immune Response in the Regression of Cervical Intraepithelial Neoplasia 2-3: A Prospective Population-Based Cohort Study.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5205, doi. 10.3390/ijms26115205

By:

Sustova, Pavla;
Engesæter, Birgit;
Øvestad, Irene Tveiterås;
Gudlaugsson, Einar G.;
Ghiasvand, Reza;
Skaland, Ivar;
Baak, Jan P. A.;
Tropé, Ameli;
Janssen, Emiel A. M.;
Munk, Ane Cecilie

Publication type:

Article

Molecular mechanisms and therapeutic strategies for small‑cell lung cancer transformation after TKI therapy in EGFR‑mutated lung adenocarcinoma (Review).

Published in:

Molecular & Clinical Oncology, 2025, v. 23, n. 1, p. N.PAG, doi. 10.3892/mco.2025.2857

By:

Zhang, Hongbing;
Gao, Hongye;
Gao, Penghu;
Liu, Hongyu;
Chen, Jun

Publication type:

Article

Relationship between the protein expression of ARID1A, ARID1B and ARID2 with the clinicopathological characteristics of colorectal cancer.

Published in:

Biomedical Reports, 2025, v. 23, n. 1, p. N.PAG, doi. 10.3892/br.2025.1997

By:

Mongkolwat, Wariya;
Sonthi, Phattarapon;
Somsuan, Keerakarn;
Aluksanasuwan, Siripat;
Samol, Ratirath;
Sakulsak, Natthiya;
Wanna-Udom, Sasithorn

Publication type:

Article

GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1588646

By:

Luo, Kexin;
Liu, Meihan;
Peng, Zhongqin;
Zhao, Haiyang;
Li, Guoyi;
Cai, Yuanze;
Lei, Yumeng;
Zhang, Hongpan;
Zhao, Yongsheng

Publication type:

Article

Identification of a Novel TP63 Variant in a Chinese Patient with Orofacial Clefts and Ectrodactyly: Case Report and Literature Review.

Published in:

Cleft Palate Craniofacial Journal, 2025, v. 62, n. 7, p. 1263, doi. 10.1177/10556656241241132

By:

Jiang, Leheng;
Jiang, Chanyuan;
Song, Tao;
Wang, Yongqian;
Si, Nuo;
Li, Haidong;
Yin, Ningbei

Publication type:

Article

Preface : Invited Issue Editor, Professor Tai-Tong Wong and the Cancer Predisposition Syndrome.

Published in:

Journal of Korean Neurosurgical Society, 2025, v. 68, n. 3, p. 249, doi. 10.3340/jkns.2025.0063

By:

Phi, Ji Hoon;
Wong, Tai-Tong;
Kim, Seung-Ki

Publication type:

Article

Li-Fraumeni Syndrome : Current Strategies and Future Perspectives.

Published in:

Journal of Korean Neurosurgical Society, 2025, v. 68, n. 3, p. 305, doi. 10.3340/jkns.2025.0050

By:

Lee, Ji Won

Publication type:

Article

Editors' Pick in May 2025.

Published in:

Journal of Korean Neurosurgical Society, 2025, v. 68, n. 3, p. 247, doi. 10.3340/jkns.2025.0080

By:

Yang, Hee-Jin

Publication type:

Article

Germline Variants in Pediatric Cancer : Based on Oncogenic Pathways.

Published in:

Journal of Korean Neurosurgical Society, 2025, v. 68, n. 3, p. 350, doi. 10.3340/jkns.2025.0011

By:

Kim, Joo Whan

Publication type:

Article

Management Strategies of Neurofibromatosis Type 2 in Pediatric Patients : Challenges and Emerging Therapies.

Published in:

Journal of Korean Neurosurgical Society, 2025, v. 68, n. 3, p. 278, doi. 10.3340/jkns.2024.0237

By:

Lee, Jong Seok

Publication type:

Article

The tumor suppressor FAT1 controls YAP/TAZ protein degradation and tumor cell proliferation through E3 ligase MIB2.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325535

By:

Li, Rui;
Strilic, Boris;
Jin, Young-June;
Shao, Jingchen;
Peng, Yundong;
Wang, Lei;
Quan, Qi;
Wang, Zhiyong;
Graumann, Johannes;
Gutkind, J. Silvio;
Wettschureck, Nina;
Offermanns, Stefan

Publication type:

Article

LTF as a Potential Prognostic and Immunological Biomarker in Glioblastoma.

Published in:

Biochemical Genetics, 2025, v. 63, n. 3, p. 2347, doi. 10.1007/s10528-024-10716-6

By:

Qiu, Kai;
Ding, Daling;
Zhang, Fengjiang;
Yang, Bo

Publication type:

Article

"Unlocking the potential of phytochemicals in cancer therapy".

Published in:

Natural Product Research, 2025, v. 39, n. 12, p. 3606, doi. 10.1080/14786419.2024.2371106

By:

Shanmugam, Geetha

Publication type:

Article

Bryophyllum pinnatum Induces p53‐Dependent Apoptosis of Colorectal Cancer Cells via Increased Intracellular ROS and G2/M Cell‐Cycle Arrest In Vitro and Validated in Silico by Molecular Docking.

Published in:

Cell Biology International, 2025, v. 49, n. 5, p. 534, doi. 10.1002/cbin.70004

By:

Mukherjee, Sumoyee;
Banik, Sheuli Kangsa;
Chakraborty, Sourio;
Das, Tanya;
Choudhury, Manabendra Dutta;
Tripathi, Anusri

Publication type:

Article

Poor prognostic implication of CDKN2 deletion in adult patients with Philadelphia chromosome-positive ALL.

Published in:

Blood Cancer Journal, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41408-025-01303-y

By:

Park, So Yeon;
Kwag, Daehun;
Jung, Jin;
Min, Gi June;
Park, Sung-Soo;
Park, Silvia;
Lee, Sung-Eun;
Cho, Byung-Sik;
Eom, Ki-Seong;
Kim, Yoo-Jin;
Kim, Hee-Je;
Min, Chang-Ki;
Cho, Seok-Goo;
Kim, Yonggoo;
Kim, Myungshin;
Lee, Seok;
Yoon, Jae-Ho

Publication type:

Article

Role of FOXN3 and long noncoding RNA NEAT1 as potential predisposing factors for development of Helicobacter pyloriassociated gastric adenocarcinoma.

Published in:

Microbes & Infectious Diseases, 2025, v. 6, n. 2, p. 830, doi. 10.21608/MID.2024.342407.2385

By:

Elawady, Basma Ahmed;
Sabry, Dina;
Elshobaky, Mustafa Ali;
Eletreby, Rasha;
Gohar, Noha Mahmoud;
Abdelgwad, Marwa

Publication type:

Article

Suppression of MRPL23 induces cellular senescence in hepatocellular carcinoma by targeting HMGB1.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02885-6

By:

Huang, Ya-Bin;
Xu, Shi-meng;
Li, Min;
Chen, Jin;
Lu, Cui-Hua;
Liu, Qing-qing

Publication type:

Article

Deciphering the dual role of autophagy in gastric cancer and gastroesophageal junction cancer: from tumor suppression to cancer progression.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02802-x

By:

Lei, Lili;
Zhang, Junling;
Wei, Ran;
Dong, Bingqi;
Wang, Xin;
Zhou, Ying

Publication type:

Article

TTP as Tumor Suppressor and Inflammatory Regulator in Oral Carcinogenesis.

Published in:

Journal of Dental Research, 2025, v. 104, n. 7, p. 795, doi. 10.1177/00220345251316828

By:

Ferri, D.M.;
Ayre, M.;
Ariza Bareño, L.;
Stedile, M.;
DiGaudio, A.V.;
Fernandez Ugazio, G.;
Kordon, E.C.;
Blackshear, P.J.;
Urtreger, A.;
Raimondi, A.R.

Publication type:

Article

A Familial Case of 1q31.2q32.2 Deletion with No Phenotypic Presentation.

Published in:

Cytogenetic & Genome Research, 2025, v. 165, n. 1, p. 23, doi. 10.1159/000543937

By:

Littlefield, Rebecca;
Weiss, Jennifer;
Zakas, Anna

Publication type:

Article

Non-recurrent mutations and copy number changes predominate pituitary adenoma genomes.

Published in:

European Journal of Endocrinology, 2025, v. 192, n. 5, p. 590, doi. 10.1093/ejendo/lvaf086

By:

Mohan, Dipika R;
Paes, Ticiana;
Mebarak, Jacobo Buelvas;
Meredith, David M;
Soares, Beatriz;
Vaz, Victor;
Carroll, Rona S;
Kaiser, Ursula B;
Smith, Timothy R;
Bi, Wenya L;
Lerario, Antonio M;
Abreu, Ana Paula

Publication type:

Article

Breaking Barriers; Phytoestrogens in the Fight Against Triple‐Negative Breast Cancer: A Comprehensive Review.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 4, p. 1211, doi. 10.1002/med.22107

By:

Sohel, Md

Publication type:

Article

基于生物材料的肿瘤防治和器官保护一体化.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 3, p. 233, doi. 10.3872/j.issn.1007-385x.2025.03.001

By:

钟锐;
季珂钦;
薛芊;
高洁

Publication type:

Article

Adipocyte/Tumor cell crosstalk via IGF-1/TXNIP axis promotes malignancy and endocrine resistance in breast cancer.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02262-4

By:

Caruso, Amanda;
Accattatis, Felice Maria;
Giordano, Cinzia;
Gelsomino, Luca;
Del Console, Piercarlo;
Fiorita, Maria Francesca;
Gyorffy, Balazs;
Bianchi, Laura;
Carleo, Alfonso;
De Salvo, Rossana;
Simões, Bruno M;
Clarke, Robert B;
Memeo, Lorenzo;
Colarossi, Cristina;
Aiello, Eleonora;
Conforti, Francesco;
Fuqua, Suzanne A W;
Todaro, Matilde;
Stassi, Giorgio;
Morelli, Catia

Publication type:

Article

Epigenetic modifications in follicular cell-derived thyroid cancer: new dimensions in pathogenesis and treatment.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1549477

By:

Han, Yanmei;
Wu, Bian;
Tan, Jie;
Wu, Ruolin;
Wang, Jingjing;
Ren, Xiaojing;
Zhang, Yajing;
Gao, Zairong;
Xia, Xiaotian

Publication type:

Article

Distribution and potential involvement of PTEN in the innate immune response during viral infections in Cherry Valley ducks.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1570872

By:

Chen, Wende;
Han, Shaojie;
Li, Rong;
Li, Shuo;
Cao, Zhi;
Pan, Qing;
Li, Gen

Publication type:

Article

Genomic landscape and homologous recombination repair deficiency signature in stage I-III and de novo stage IV primary breast cancers.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyaf089

By:

Jeon, June E;
Chen, Kuei-Ting;
Madison, Russell;
Schrock, Alexa B;
Sokol, Ethan;
Levy, Mia A;
Rozenblit, Mariya;
Huang, Richard S P;
Pusztai, Lajos

Publication type:

Article

MDM2 as a therapeutic target in advanced biliary tract cancers.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyaf094

By:

Spencer, Kristen R;
King, Gentry G

Publication type:

Article

Epigenetic Therapies in Melanoma—Targeting DNA Methylation and Histone Modification.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1188, doi. 10.3390/biomedicines13051188

By:

Tigu, Adrian Bogdan;
Ivancuta, Andrei;
Uhl, Andrada;
Sabo, Alexandru Cristian;
Nistor, Madalina;
Mureșan, Ximena-Maria;
Cenariu, Diana;
Timis, Tanase;
Diculescu, Doru;
Gulei, Diana

Publication type:

Article

Circular Nucleic Acids Act as an Oncogenic MicroRNA Sponge to Inhibit Hepatocellular Carcinoma Progression.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1171, doi. 10.3390/biomedicines13051171

By:

Zhang, Qianyi;
Sun, Pengcheng;
Hu, Guang;
Yu, Xuanyao;
Zhang, Wen;
Feng, Xuan;
Yu, Lan;
Zhang, Pengfei

Publication type:

Article

Uncovering a Novel Role of ROR1 in the Epigenetic Regulation of Tumor Suppressor Gene CREB3L1 in Triple-Negative Breast Cancer Cells.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 734, doi. 10.3390/biom15050734

By:

Reed, Victoria L.;
Lalu, Eric;
Yoon, Leena;
Fultang, Norman;
Peethambaran, Bela

Publication type:

Article

Radon Exposure and Cancer Risk: Assessing Genetic and Protein Markers in Affected Populations.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 506, doi. 10.3390/biology14050506

By:

Kashkinbayev, Yerlan;
Kazhiyakhmetova, Baglan;
Altaeva, Nursulu;
Bakhtin, Meirat;
Tarlykov, Pavel;
Saifulina, Elena;
Aumalikova, Moldir;
Ibrayeva, Danara;
Bolatov, Aidos

Publication type:

Article

Is miR-10a a tumor suppressor that modulates proliferation and invasion in high-grade bladder cancer?

Published in:

Oncology Research, 2025, v. 33, n. 6, p. 1377, doi. 10.32604/or.2025.055306

By:

RODRIGUES, THAINá;
CANDIDO, PATRíCIA;
MALUF, FERES CAMARGO;
ROMãO, POLIANA;
MIOSHI, CAROLINA MIE;
GUIMARãES, VANESSA RIBEIRO;
CAMARGO, JULIANA ALVES DE;
SILVA, KARINA SERAFIM DA;
SANTOS, GABRIEL ARANTES DOS;
SILVA, IRAN AMORIM;
LEITE, KATIA RAMOS MOREIRA;
NAHAS, WILLIAM C.;
REIS, SABRINA T.;
PIMENTA, RUAN;
VIANA, NAYARA IZABEL

Publication type:

Article

Metachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database.

Published in:

British Journal of Surgery, 2025, v. 112, n. 4, p. 1, doi. 10.1093/bjs/znaf061

By:

Zalevskaja, K;
Ojala, K;
Petrov, A;
Haupt, S;
Sunde, L;
Bernstein, I;
Jenkins, M A;
Aretz, S;
Nielsen, M;
Capella, G;
Balaguer, F;
Evans, D G;
Burn, J;
Holinski-Feder, E;
Bertario, L;
Bonanni, B;
Lindblom, A;
Levi, Z;
Macrae, F;
Winship, I

Publication type:

Article

Laryngeal Cancer in the Modern Era: Evolving Trends in Diagnosis, Treatment, and Survival Outcomes.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 10, p. 3367, doi. 10.3390/jcm14103367

By:

Hut, Alexandru-Romulus;
Boia, Eugen Radu;
Para, Diana;
Iovanescu, Gheorghe;
Horhat, Delia;
Mikša, Loredan;
Chiriac, Maria;
Galant, Raphaël;
Motofelea, Alexandru Catalin;
Balica, Nicolae Constantin

Publication type:

Article

Advancements in Gene Therapy for Non-Small Cell Lung Cancer: Current Approaches and Future Prospects.

Published in:

Genes, 2025, v. 16, n. 5, p. 569, doi. 10.3390/genes16050569

By:

Ziółkowska-Suchanek, Iwona;
Rozwadowska, Natalia

Publication type:

Article

Dysregulation of Locus-Specific Repetitive Elements in TCGA Pan-Cancers.

Published in:

Genes, 2025, v. 16, n. 5, p. 528, doi. 10.3390/genes16050528

By:

Wang, Chao;
Liang, Chun

Publication type:

Article

The Basis for Targeting the Tumor Macrophage Compartment in Glioblastoma Immunotherapy.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1631, doi. 10.3390/cancers17101631

By:

Eckert, Thomas;
Walton, Chase;
Bell, Marcus;
Small, Coulter;
Rowland, Nathan C.;
Rivers, Charlotte;
Zukas, Alicia;
Lindhorst, Scott;
Fecci, Peter;
Strickland, Ben A.

Publication type:

Article

Molecular Mechanisms of Drug Resistance in Clear Cell Renal Cell Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1613, doi. 10.3390/cancers17101613

By:

Bianchi, Nicoletta;
Ancona, Pietro;
Aguiari, Gianluca

Publication type:

Article

The Central Role of Ribosomal Proteins in p53 Regulation.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1597, doi. 10.3390/cancers17101597

By:

Lindström, Mikael S.

Publication type:

Article

Different Mechanisms in Doxorubicin-Induced Neurotoxicity: Impact of BRCA Mutations.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4736, doi. 10.3390/ijms26104736

By:

Bhatt, Kriti S.;
Singh, Aman;
Marwaha, Gursharan S.;
Ravendranathan, Naresh;
Sandhu, Inderbir S.;
Kim, Kristen;
Singh, Eesha;
Frisbee, Jefferson C.;
Singh, Krishna K.

Publication type:

Article

Correction: Beylerli et al. MiRNAs as Noninvasive Biomarkers and Therapeutic Agents of Pituitary Adenomas. Int. J. Mol. Sci. 2020, 21 , 7287.

Published in:

2025

By:

Beylerli, Ozal;
Beeraka, Narasimha M.;
Gareev, Ilgiz;
Pavlov, Valentin;
Yang, Guang;
Liang, Yanchao;
Aliev, Gjumrakch

Publication type:

Correction Notice

锌指结构转录因子锌指蛋白 148 和 SP5 对 P53 转录活性的作用.

Published in:

Chinese Journal of Biochemistry & Molecular Biology, 2025, v. 41, n. 5, p. 707, doi. 10.13865/j.cnki.cjbmb.2025.03.1514

By:

王代伟;
周晨;
张品正;
王旭莹;
李佳文;
马雨凯;
严佳琦;
王志婷;
王佳琪;
郭志义

Publication type:

Article

Therapeutic Potential of Translational Readthrough at Disease‐Associated Premature Termination Codons From Tumor Suppressor Genes.

Published in:

IUBMB Life, 2025, v. 77, n. 5, p. 1, doi. 10.1002/iub.70018

By:

Torices, Leire;
Nunes‐Xavier, Caroline E.;
Pulido, Rafael

Publication type:

Article

Pathogenic TP53 mutations influence chemotherapy response and survival rate of patients with HPV-negative oral carcinomas.

Published in:: Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2022, v. 79, n. 11, p. 1063, doi. 10.2298/VSP200525068J
Publication type:: Article