Works matching DE "CYCLIN-dependent kinase inhibitors"

Results: 1266

A Pituitary Macroadenoma Cosecreting Prolactin and Growth Hormone in a Patient With Multiple Endocrine Neoplasia Type 4 Open Access.

Published in:

2025

By:

Green, Leah;
Simpson, Millie;
Bahri, Aufar;
Fong, Amy;
Manning, Patrick

Publication type:

Case Study

Emerging cardiovascular toxicity associated with CDK4/6 inhibitors: real-world insights from the FDA adverse event reporting system.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1558128

By:

Liu, Wensheng;
Gao, Feifei;
Song, Xue;
Chen, Hao;
She, Youjun;
Liu, Jiyong;
Du, Qiong

Publication type:

Article

Baseline cell cycle and immune profiles indicate CDK4/6 inhibitor response in metastatic HR + /HER2- breast cancer.

Published in:

NPJ Breast Cancer, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41523-025-00767-2

By:

Tzetzo, Stephanie L.;
Schultz, Emily;
Wang, Jianxin;
Rosenheck, Hanna R.;
Mahan, Sidney;
Knudsen, Erik S.;
Witkiewicz, Agnieszka K.

Publication type:

Article

Diagnostic Utility of Intratumoral Susceptibility Signals in Adult Diffuse Gliomas: Tumor Grade Prediction and Correlation with Molecular Markers Within the WHO CNS5 (2021) Classification.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 11, p. 4004, doi. 10.3390/jcm14114004

By:

Tudela Martínez, José Ignacio;
Vázquez Sáez, Victoria;
Carbonell, Guillermo;
Rodrigo Lara, Héctor;
Guzmán-Aroca, Florentina;
Berna Mestre, Juan de Dios

Publication type:

Article

Response to Venkataraman and Mokbel Free.

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 6, p. 1289, doi. 10.1093/jnci/djaf087

By:

Arecco, Luca;
Blondeaux, Eva;
Agostinetto, Elisa;
Azambuja, Evandro De;
Lambertini, Matteo;
Mastro, Lucia Del

Publication type:

Article

Clinical significance of cyclin-dependent kinase inhibitor 3 in hepatocellular carcinoma.

Published in:

Molecular & Clinical Oncology, 2025, v. 23, n. 1, p. N.PAG, doi. 10.3892/mco.2025.2860

By:

Liu, Xing;
Chang, Kaiyuan;
Liu, Jian

Publication type:

Article

Poor prognostic implication of CDKN2 deletion in adult patients with Philadelphia chromosome-positive ALL.

Published in:

Blood Cancer Journal, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41408-025-01303-y

By:

Park, So Yeon;
Kwag, Daehun;
Jung, Jin;
Min, Gi June;
Park, Sung-Soo;
Park, Silvia;
Lee, Sung-Eun;
Cho, Byung-Sik;
Eom, Ki-Seong;
Kim, Yoo-Jin;
Kim, Hee-Je;
Min, Chang-Ki;
Cho, Seok-Goo;
Kim, Yonggoo;
Kim, Myungshin;
Lee, Seok;
Yoon, Jae-Ho

Publication type:

Article

Assessment of CDKN2A homozygous and heterozygous deletions in gliomas across multiple detection platforms.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14266-x

By:

Li, Hainan;
Luo, Ningning;
Fan, Chongzhu;
Han, Tiantian;
Wei, Xuemin;
Zhang, Xing;
Dai, Lijun;
Ye, Lei;
Chen, Dongsheng;
Cai, Linbo;
Li, Zhi

Publication type:

Article

Progressive multifocal leukoencephalopathy during 4 years of Palbociclib for advanced breast cancer with a history of follicular lymphoma patient.

Published in:

2025

By:

Koyamada, Ryosuke;
Nishihara, Mariko;
Masaki, Tetsuhiro;
Shimada, Tomohito;
Ishikawa, Kazuhiro;
Hashimoto, Jun;
Mori, Nobuyoshi;
Namai, Asami;
Yokoo, Hideaki;
Takahashi, Kenta;
Suzuki, Tadaki;
Nakamichi, Kazuo;
Mori, Shinichiro

Publication type:

Case Study

CDK5 targets p21<sup>CIP1</sup> to regulate thyroid cancer cell proliferation and malignancy in patients.

Published in:

Molecular Medicine Reports, 2025, v. 32, n. 1, p. N.PAG, doi. 10.3892/mmr.2025.13547

By:

Tung, Min-Che;
Oner, Muhammet;
Soong, Shiuan-Woei;
Cheng, Pang-Ting;
Li, Yu-Hsuan;
Chen, Mei-Chih;
Chou, Chen-Kai;
Kang, Hong-Yo;
Lin, Frank Cheau-Feng;
Tsai, Stella Chin-Shaw;
Lin, Ho

Publication type:

Article

Cutting‐Edge Therapy and Immune Escape Mechanisms in EBV‐Associated Tumors.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 4, p. 1184, doi. 10.1002/med.22104

By:

Wang, Jie;
Wang, Rong;
Wang, Meifeng;
Ge, Junshang;
Wang, Yian;
Li, Yanhan;
Chen, Changan;
He, Jiale;
Zheng, Boshu;
Xu, Meifang;
Jiang, Xianjie;
Liu, Yuhang;
Chen, Mingfen;
Long, Jun

Publication type:

Article

Cuproptosis-related gene signatures define the immune microenvironment in diabetic nephropathy.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0321636

By:

Luo, Hongmin;
Cao, Yuxuan;
Guo, Liping;
Li, Hui;
Yuan, Yingying;
Lu, Fan

Publication type:

Article

Recent advancements in biomarkers and molecular diagnostics in hormonal receptor‐positive breast cancer.

Published in:

Histopathology, 2025, v. 87, n. 1, p. 3, doi. 10.1111/his.15395

By:

Wang, Yihong;
Liu, Liu;
Graff, Stephanie L.;
Cheng, Liang

Publication type:

Article

CDK4/6 inhibition in early and advanced hormone receptor-positive, HER2-negative breast cancer.

Published in:

Expert Review of Anticancer Therapy, 2025, v. 25, n. 6, p. 675, doi. 10.1080/14737140.2025.2498994

By:

Yarlagadda, Sudha;
de Oliveira Andrade, Matheus;
Nanda, Rita

Publication type:

Article

A Vitiligo-like Cutaneous Reaction Induced by Ribociclib in Advanced Breast Cancer: An Unusual Case Report from Colombia.

Published in:

Diseases, 2025, v. 13, n. 5, p. 158, doi. 10.3390/diseases13050158

By:

Montenegro, John Fernando;
Rivas-Tafurt, Giovanna Patricia;
Vidal-Cañas, Sinthia;
Diaz-Diaz, Miguel Ángel;
Bermudez, Cesar Eduardo;
Florez, Daniel;
Bravo-Gustin, Andres Felipe;
Liscano, Yamil

Publication type:

Article

Cyclin-Dependent Kinase 4/6 Inhibitors Combined with Radiotherapy in Curative Breast Cancer Patients Induced Pneumonitis: A Case Report.

Published in:

Life (2075-1729), 2025, v. 15, n. 5, p. 709, doi. 10.3390/life15050709

By:

Hou, Pei-Yu

Publication type:

Article

Allelic expression imbalance of CDKN2A variants in childhood acute lymphoblastic leukemia.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 835, doi. 10.1007/s13402-025-01049-6

By:

Tang, Zhexuan;
Pei, Kunlin;
Xu, Haoyu;
Zheng, Yongzhi;
Zhuang, Shuquan;
Weng, Kaizhi;
He, Yingyi;
Wu, Jing;
Zhang, Hui

Publication type:

Article

USE OF CYCLIN-DEPENDENT KINASE 4 AND 6 INHIBITORS IN TREATING METASTATIC BREAST CANCER - A YEAR-LONG EXPERIENCE OF SUBOTICA GENERAL HOSPITAL IN PATIENT FOLLOW-UP.

Published in:

Medical Review / Medicinski Pregled, 2024, v. 77, n. 3/4, p. 94, doi. 10.2298/MPNS2404094B

By:

ZELEN, Teodora BRDAR;
JOVIŠEVIĆ, Marija;
PRICA, Anja

Publication type:

Article

Should CDK4/6 inhibitors replace chemotherapy in HR+ /HER2− metastatic breast cancer with visceral crisis? Evaluating the emerging evidence.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02699-6

By:

Orlandi, Armando

Publication type:

Article

mRNA sequencing analysis and growth inhibitory effects of palbociclib on cell lines from canine histiocytic proliferative disorders.

Published in:

Veterinary & Comparative Oncology, 2022, v. 20, n. 3, p. 587, doi. 10.1111/vco.12812

By:

Hirabayashi, Miyuki;
Chambers, James K.;
Tani, Akiyoshi;
Tomiyasu, Hirotaka;
Motegi, Tomoki;
Rimpo, Kenji;
Nakayama, Hiroyuki;
Uchida, Kazuyuki

Publication type:

Article

In vitro study to assess the efficacy of CDK4/6 inhibitor Palbociclib (PD‐0332991) for treating canine mammary tumours.

Published in:

Veterinary & Comparative Oncology, 2019, v. 17, n. 4, p. 507, doi. 10.1111/vco.12514

By:

Schoos, Alexandra;
Knab, Vanessa M.;
Gabriel, Cordula;
Tripolt, Sabrina;
Wagner, Daniela A.;
Bauder, Barbara;
Url, Angelika;
Fux, Daniela A.

Publication type:

Article

Investigation of the cytotoxic effect of flavopiridol in canine lymphoma cell lines.

Published in:

Veterinary & Comparative Oncology, 2016, v. 14, p. 95, doi. 10.1111/vco.12130

By:

Ema, Y.;
Igase, M.;
Takeda, Y.;
Yanase, T.;
Umeki, S.;
Hiraoka, H.;
Okuda, M.;
Mizuno, T.

Publication type:

Article

Palbociclib inhibits the progression of head and neck cancer and improves the Cetuximab response under specific condition in vitro and in vivo.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09423-7

By:

Li, Ruichen;
Wang, Qi;
Zhao, Yang;
Zhu, Yi;
Wang, Xiaoshen

Publication type:

Article

The role of CXCL1 in crosstalk between endocrine resistant breast cancer and fibroblast.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-023-09119-4

By:

Pandithar, Sneha;
Galke, Daniel;
Akume, Ahone;
Belyakov, Artem;
Lomonaco, Dominick;
Guerra, Amirah A.;
Park, Jay;
Reff, Olivia;
Jin, Kideok

Publication type:

Article

CDK11 kinase activity is required to protect sister chromatid cohesion at centromeres in mitosis.

Published in:

Chromosome Research, 2014, v. 22, n. 3, p. 267, doi. 10.1007/s10577-013-9400-x

By:

Rakkaa, Tarik;
Escudé, Christophe;
Giet, Régis;
Magnaghi-Jaulin, Laura;
Jaulin, Christian

Publication type:

Article

Analyzing the scaffold diversity of cyclin‐dependent kinase inhibitors and revisiting the clinical and preclinical pipeline.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 2, p. 654, doi. 10.1002/med.21856

By:

Bhurta, Deendyal;
Bharate, Sandip B.

Publication type:

Article

Real-world experience with CDK4/6 inhibitors in hormone receptor-positive metastatic and recurrent breast cancer: findings from an Asian population.

Published in:

Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01458-1

By:

Chen, Bo-Fang;
Tsai, Yi-Fang;
Chao, Ta-Chung;
Lien, Pei-Ju;
Lin, Yen-Shu;
Feng, Chin-Jung;
Chen, Yen-Jen;
Cheng, Han-Fang;
Liu, Chun-Yu;
Lai, Jiun-I;
Tseng, Ling-Ming;
Huang, Chi-Cheng

Publication type:

Article

Clinical and Genomic Analysis of Patients with Short Survival after Surgery for Esophageal Squamous Cell Carcinoma.

Published in:

Digestive Diseases, 2023, v. 41, n. 3, p. 353, doi. 10.1159/000527983

By:

Gao, Lu;
Guo, Rong-Yun;
Lu, Hao;
Shi, Zhi-Hua;
Liu, Jun-Feng

Publication type:

Article

MicroRNA-93 Targets p21 and Promotes Proliferation in Mycosis Fungoides T Cells.

Published in:

Dermatology (10188665), 2021, v. 237, n. 2, p. 277, doi. 10.1159/000505743

By:

Gluud, Maria;
Fredholm, Simon;
Blümel, Edda;
Willerslev-Olsen, Andreas;
Buus, Terkild Brink;
Nastasi, Claudia;
Krejsgaard, Thorbjørn;
Bonefeld, Charlotte Menné;
Woetmann, Anders;
Iversen, Lars;
Litman, Thomas;
Geisler, Carsten;
Ødum, Niels;
Lindahl, Lise M.

Publication type:

Article

Evaluation of Cyclin-Dependent Kinase Inhibitor 2A and Hepatocyte Nuclear Factor-1A Gene Polymorphisms in Coronary Artery Diseases.

Published in:

Zagazig University Medical Journal, 2024, v. 30, n. 3, p. 859, doi. 10.21608/ZUMJ.2022.161460.2636

By:

Ibrahimm, Magdy;
Sherif, Abdelsalam;
Mohamed, Dina Salah;
Samy, Walaa

Publication type:

Article

Precision diagnosis and treatment of breast cancer in the post-CDK4/6 inhibitor era.

Published in:

China Oncology, 2025, v. 35, n. 3, p. 273, doi. 10.19401/j.cnki.1007-3639.2025.03.003

By:

LI Bin;
TAO Zhonghua;
HU Xichun

Publication type:

Article

"Subtype-precise" therapy leads diagnostic and therapeutic innovations: a new pattern for precision treatment of breast cancer.

Published in:

China Oncology, 2024, v. 34, n. 11, p. 1045, doi. 10.19401/j.cnki.1007-3639.2024.11.007

By:

ZHANG Siwei;
MA Ding;
JIANG Yizhou;
SHAO Zhimin

Publication type:

Article

Decreased mitochondrial transcription factor A and mitochondrial DNA copy number promote cyclin-dependent kinase inhibitor 1A expression and reduce tumorigenic properties of colorectal cancer cells.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01538-4

By:

Buchwaldt, Jessika;
Fritsch, Tania;
Hartmann, Monika;
Witzel, Hagen Roland;
Kloth, Michael;
Roth, Wilfried;
Tagscherer, Katrin E.;
Hartmann, Nils

Publication type:

Article

Prognostic significance of systemic immune inflammation indices and prognostic nutritional index before CDK4/6 inhibitor therapy in hormone receptor positive, HER2 negative metastatic breast cancer patients.

Published in:

Pamukkale Medical Journal, 2023, v. 16, n. 4, p. 682, doi. 10.31362/patd.1268419

By:

Demirel, Burçin Çakan;
Yaren, Arzu;
Demiray, Atike Gökçen;
Taşköylü, Burcu Yapar;
Doğan, Tolga;
Özdemir, Melek;
Kantar, Taliha Güçlü;
Karan, Canan;
Değirmencioğlu, Serkan;
Doğu, Gamze Gököz

Publication type:

Article

From Roscovitine to CYC202 to Seliciclib -- from bench to bedside: discovery and development.

Published in:

BioDiscovery, 2017, p. 1, doi. 10.7750/BioDiscovery.2013.10.1

By:

Zhelev, Nikolai;
Trifonov, Dimitar;
Shudong Wang;
Hassan, Moustapha;
El Serafi, Ibrahim;
Mitev, Vanio

Publication type:

Article

Modelling c-Abl Signalling in Activated Neutrophils: the Anti-inflammatory Effect of Seliciclib.

Published in:

BioDiscovery, 2017, p. 1, doi. 10.7750/BioDiscovery.2013.7.4

By:

Jackson, Robert C.;
Radivoyevitch, Tomas

Publication type:

Article

A Sensitive, Green, and Fast LC–MS/MS Analytical Method for the Quantification of Ribociclib: Evaluation of the Metabolic Stability in HLMs.

Published in:

Separations (2297-8739), 2023, v. 10, n. 9, p. 472, doi. 10.3390/separations10090472

By:

Attwa, Mohamed W.;
Abdelhameed, Ali S.;
Kadi, Adnan A.

Publication type:

Article

Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00653-3

By:

Freitag, Thomas;
Kaps, Philipp;
Ramtke, Justus;
Bertels, Sarah;
Zunke, Emily;
Schneider, Björn;
Becker, Anne-Sophie;
Koczan, Dirk;
Dubinski, Daniel;
Freiman, Thomas M.;
Wittig, Felix;
Hinz, Burkhard;
Westhoff, Mike-Andrew;
Strobel, Hannah;
Meiners, Franziska;
Wolter, Daniel;
Engel, Nadja;
Troschke-Meurer, Sascha;
Bergmann-Ewert, Wendy;
Staehlke, Susanne

Publication type:

Article

NF2: An underestimated player in cancer metabolic reprogramming and tumor immunity.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00627-5

By:

Xu, Duo;
Yin, Shiyuan;
Shu, Yongqian

Publication type:

Article

Osimertinib and palbociclib in an EGFR-mutated NSCLC with primary CDK4 amplification after progression under osimertinib.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00607-9

By:

de Jager, Vincent D.;
Stigt, Jos A.;
Niemantsverdriet, Maarten;
ter Elst, Arja;
van der Wekken, Anthonie J.

Publication type:

Article

Determinants of response to CDK4/6 inhibitors in the real-world setting.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00438-0

By:

Witkiewicz, Agnieszka K.;
Schultz, Emily;
Wang, Jianxin;
Hamilton, Deanna;
Levine, Ellis;
O'Connor, Tracey;
Knudsen, Erik S.

Publication type:

Article

EXPLORING APOPTOTIC EFFECTS OF STENOENDEMIC ACINOS ORONTIUS PLANT EXTRACTS IN GR-M MELANOMA CELLS: INITIAL FINDINGS.

Published in:

Genetics & Applications, 2023, p. 66

By:

Lejla, Lasić;
Jasna, Hanjalić Kurtović;
Lejla, Ušanović;
Merima, Miralem;
Belma, Kalamujić Stroil;
Naris, Pojskić

Publication type:

Article

QTc prolongation across CDK4/6 inhibitors: a systematic review and meta-analysis of randomized controlled trials.

Published in:

JNCI Cancer Spectrum, 2024, v. 8, n. 5, p. 1, doi. 10.1093/jncics/pkae078

By:

Murad, Bruno;
Reis, Pedro C A;
Marinho, Alice Deberaldini;
Comini, Ana Carolina Marin;
Xavier, Débora Pinheiro;
Pessoa, Beatriz Mella Soares;
Raheem, Farah;
Ernst, Brenda;
Mina, Lida A;
Batalini, Felipe

Publication type:

Article

Double-Faced Immunological Effects of CDK4/6 Inhibitors on Cancer Treatment: Challenges and Perspectives.

Published in:

Bioengineering (Basel), 2024, v. 11, n. 11, p. 1084, doi. 10.3390/bioengineering11111084

By:

Liu, Yongqin;
Deng, Yiying;
Yang, Chang;
Naranmandura, Hua

Publication type:

Article

Network pharmacological approach combined with weighted gene co-expression network analysis identifies CDKN2A as the keg target of Changweiqing against colorectal cancer.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00405-8

By:

Zushuai, Ma;
Yanrong, Ji;
Chengdu, Zhao;
Xu, Zhu;
Qianshan, Ding

Publication type:

Article

<italic>Mnb/Dyrk1A</italic> orchestrates a transcriptional network at the transition from self-renewing neurogenic progenitors to postmitotic neuronal precursors.

Published in:

Journal of Neurogenetics, 2018, v. 32, n. 1, p. 37, doi. 10.1080/01677063.2018.1438427

By:

Shaikh, Mirja N.;
Tejedor, Francisco J.

Publication type:

Article

CDK4/6 inhibition in cancer: the cell cycle splicing connection.

Published in:

2019

By:

Sheppard, Karen E.;
AbuHammad, Shatha

Publication type:

Opinion

The role of vitamin D up-regulated protein 1 in epithelial ovarian cancer.

Published in:

European Journal of Gynaecological Oncology, 2019, v. 40, n. 4, p. 585, doi. 10.12892/ejgo4484.2019

By:

Dong-Hee Kim;
Seung-Do Choi;
Hae-Hyeog Lee;
Tae-Hee Kim;
Yeon-Suk Kim;
Yesol Kim

Publication type:

Article

Expression of Jun activation domain-binding protein 1 and p27 Kip1 in endometrial polyps and uterine leiomyomas.

Published in:

European Journal of Gynaecological Oncology, 2018, v. 39, n. 4, p. 533, doi. 10.12892/ejgo3857.2018

By:

Lee, Arum;
Kim, Tae-Hee;
Lee, Hae-Hyeog;
Kim, Jun-Mo;
Kim, Yeon-Suk

Publication type:

Article

Loss of p27 expression in endometrial carcinoma patients with recurrent tumor is significantly associated with poor survival.

Published in:

European Journal of Gynaecological Oncology, 2018, v. 39, n. 1, p. 119, doi. 10.12892/ejgo3784.2018

By:

Al-Maghrabi, J.;
Abdelrahman, A. S.;
Al-Maghrabi, B.;
Buhmeida, A.;
Abuzenadah, A.;
Al-Qahtani, M.;
Al-Ahwal, M.;
Khabaz, M. N.

Publication type:

Article