Works matching DE "ANIMAL models of Alzheimer's disease"

Results: 261

Agmatine, A Metabolite of Arginine, Improves Learning and Memory in Streptozotocin-Induced Alzheimer's Disease Model in Rats.

Published in:

Klinik Psikofarmakoloji Bulteni, 2016, v. 26, n. 4, p. 342, doi. 10.5455/bcp.20161121125642

By:

Sirvanci-Yalabik, Muge;
Sehirli, Ahmet Ozer;
Utkan, Tijen;
Aricioglu, Feyza

Publication type:

Article

A Single Biosensor for Evaluating the Levels of Copper Ion and L- Cysteine in a Live Rat Brain with Alzheimer's Disease.

Published in:

Angewandte Chemie, 2015, v. 127, n. 47, p. 14259, doi. 10.1002/ange.201508635

By:

Luo, Yongping;
Zhang, Limin;
Liu, Wei;
Yu, Yanyan;
Tian, Yang

Publication type:

Article

Multi-Frequency, Multi-Technique Pulsed EPR Investigation of the Copper Binding Site of Murine Amyloid β Peptide.

Published in:

Angewandte Chemie, 2015, v. 127, n. 5, p. 1581, doi. 10.1002/ange.201410389

By:

Donghun Kim;
Jeong Kyu Bang;
Sun Hee Kim

Publication type:

Article

Genome-wide analysis of DNA methylation profiles in a senescence-accelerated mouse prone 8 brain using whole-genome bisulfite sequencing.

Published in:

Bioinformatics, 2017, v. 33, n. 11, p. 1591, doi. 10.1093/bioinformatics/btx040

By:

Shuai Zhang;
Chunxia Qin;
Guoqiong Cao;
Limin Guo;
Chengqiang Feng;
Wensheng Zhang

Publication type:

Article

Reduction of Hippocampal Apoptosis by Intracerebroventricular Administration of Extracellular Signal-Regulated Protein Kinase and/or p38 Inhibitors in Amyloid Beta Rat Model of Alzheimer's Disease: Involvement of Nuclear-Related Factor-2 and Nuclear Factor-κ B

Published in:

Basic & Clinical Pharmacology & Toxicology, 2013, v. 112, n. 3, p. 145, doi. 10.1111/bcpt.12000

By:

Ashabi, Ghorbangol;
Alamdary, Shabnam Zeighamy;
Ramin, Mahmoudreza;
Khodagholi, Fariba

Publication type:

Article

Clearance from the mouse brain by convection of interstitial fluid towards the ventricular system.

Published in:

Fluids & Barriers of the CNS, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12987-015-0019-5

By:

Bedussi, Beatrice;
van Lier, Monique G. J. T. B.;
Bartstra, Jonas W.;
de Vos, Judith;
Siebes, Maria;
VanBavel, Ed;
Bakker, Erik N. T. P.

Publication type:

Article

Kaolin-induced chronic hydrocephalus accelerates amyloid deposition and vascular disease in transgenic rats expressing high levels of human APP.

Published in:

Fluids & Barriers of the CNS, 2015, v. 12, n. 1, p. 37, doi. 10.1186/2045-8118-12-2

By:

Silverberg, Gerald D.;
Miller, Miles C.;
Pascale, Crissey L.;
Caralopoulos, Ilias N.;
Agca, Yuksel;
Agca, Cansu;
Stopa, Edward G.

Publication type:

Article

Caspases in synaptic plasticity.

Published in:: Molecular Brain, 2012, v. 5, n. 1, p. 15, doi. 10.1186/1756-6606-5-15
Publication type:: Article

Neurovascular and Cognitive failure in Alzheimer's Disease: Benefits of Cardiovascular Therapy.

Published in:

Cellular & Molecular Neurobiology, 2016, v. 36, n. 2, p. 219, doi. 10.1007/s10571-015-0285-4

By:

Hamel, Edith;
Royea, Jessika;
Ongali, Brice;
Tong, Xin-Kang

Publication type:

Article

Concurrence of High Fat Diet and APOE Gene Induces Allele Specific Metabolic and Mental Stress Changes in a Mouse Model of Alzheimer's Disease.

Published in:

Frontiers in Behavioral Neuroscience, 2016, p. 1, doi. 10.3389/fnbeh.2016.00170

By:

Segev, Yifat;
Livne, Adva;
Mints, Meshi;
Rosenblum, Kobi

Publication type:

Article

Angiotensin-converting enzyme gene insertion-deletion polymorphism is a risk marker for Alzheimer's disease in a Chinese population: a meta-analysis of case-control studies.

Published in:

Journal of Neural Transmission, 2015, v. 122, n. 8, p. 1105, doi. 10.1007/s00702-015-1368-6

By:

Yuan, Ye;
Piao, Jin-hua;
Ma, Ke;
Lu, Na

Publication type:

Article

Staging of cognitive deficits and neuropathological and ultrastructural changes in streptozotocin-induced rat model of Alzheimer's disease.

Published in:

Journal of Neural Transmission, 2015, v. 122, n. 4, p. 577, doi. 10.1007/s00702-015-1394-4

By:

Knezovic, Ana;
Osmanovic-Barilar, Jelena;
Curlin, Marija;
Hof, Patrick;
Simic, Goran;
Riederer, Peter;
Salkovic-Petrisic, Melita

Publication type:

Article

Amyloid-β protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer's disease.

Published in:

Journal of Neural Transmission, 2011, v. 118, n. 5, p. 699, doi. 10.1007/s00702-010-0572-7

By:

Rolyan, Harshvardhan;
Feike, Ann;
Upadhaya, Ajeet;
Waha, Andreas;
Dooren, Tom;
Haass, Christian;
Birkenmeier, Gerd;
Pietrzik, Claus;
Leuven, Fred;
Thal, Dietmar

Publication type:

Article

Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer's disease: a long-term follow up study.

Published in:

Journal of Neural Transmission, 2011, v. 118, n. 5, p. 765, doi. 10.1007/s00702-011-0651-4

By:

Salkovic-Petrisic, Melita;
Osmanovic-Barilar, Jelena;
Brückner, Martina;
Hoyer, Siegfried;
Arendt, Thomas;
Riederer, Peter

Publication type:

Article

Inflammasomes as therapeutic targets for Alzheimer's disease.

Published in:

Brain Pathology, 2017, v. 27, n. 2, p. 223, doi. 10.1111/bpa.12478

By:

White, Claire S.;
Lawrence, Catherine B.;
Brough, David;
Rivers‐Auty, Jack

Publication type:

Article

Amyloid Generation and Dysfunctional Immunoproteasome Activation with Disease Progression in Animal Model of Familial Alzheimer's Disease.

Published in:

Brain Pathology, 2012, v. 22, n. 5, p. 636, doi. 10.1111/j.1750-3639.2011.00560.x

By:

Aso, Ester;
Lomoio, Selene;
López-González, Irene;
Joda, Laura;
Carmona, Margarita;
Fernández-Yagüe, Núria;
Moreno, Jesús;
Juvés, Salvador;
Pujol, Aurora;
Pamplona, Reinald;
Portero-Otin, Manuel;
Martín, Virginia;
Díaz, Mario;
Ferrer, Isidro

Publication type:

Article

Oleic Acid Ameliorates Amyloidosis in Cellular and Mouse Models of Alzheimer's Disease.

Published in:

Brain Pathology, 2011, v. 21, n. 3, p. 321, doi. 10.1111/j.1750-3639.2010.00449.x

By:

Amtul, Zareen;
Westaway, David;
Cechetto, David F.;
Rozmahel, Richard F.

Publication type:

Article

Understanding the role of progranulin in Alzheimer's disease.

Published in:

Nature Medicine, 2014, v. 20, n. 10, p. 1099, doi. 10.1038/nm.3712

By:

D'Alton, Simon;
Lewis, Jada

Publication type:

Article

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease.

Published in:

Nature Medicine, 2014, v. 20, n. 8, p. 886, doi. 10.1038/nm.3639

By:

Jo, Seonmi;
Yarishkin, Oleg;
Hwang, Yu Jin;
Chun, Ye Eun;
Park, Mijeong;
Woo, Dong Ho;
Bae, Jin Young;
Kim, Taekeun;
Lee, Jaekwang;
Chun, Heejung;
Park, Hyun Jung;
Lee, Da Yong;
Hong, Jinpyo;
Kim, Hye Yun;
Oh, Soo-Jin;
Park, Seung Ju;
Lee, Hyo;
Yoon, Bo-Eun;
Kim, YoungSoo;
Jeong, Yong

Publication type:

Article

Mouse modeling of Alzheimer's disease.

Published in:

Nature Genetics, 2015, v. 47, n. 4, p. 311, doi. 10.1038/ng.3267

By:

LaFlamme, Brooke

Publication type:

Article

THE CANINE SAND MAZE: AN APPETITIVE SPATIAL MEMORY PARADIGM SENSITIVE TO AGE-RELATED CHANGE IN DOGS.

Published in:

Journal of the Experimental Analysis of Behavior, 2011, v. 95, n. 1, p. 109, doi. 10.1901/jeab.2011.95-109

By:

Salvin, Hannah E.;
Mcgreevy, Paul D.;
Sachdev, Perminder S.;
Valenzuela, Michael J.

Publication type:

Article

Matrine improves cognitive impairment and modulates the balance of Th17/Treg cytokines in a rat model of Aβ<sub>1-42</sub>-induced Alzheimer's disease.

Published in:

Central European Journal of Immunology, 2015, v. 40, n. 4, p. 411, doi. 10.5114/ceji.2015.56961

By:

YANFENG ZHANG;
MEIFENG LIU;
HONGRI SUN;
KUIMING YIN

Publication type:

Article

Exercise and the brain: a slap on the HAND.

Published in:

Journal of NeuroVirology, 2013, v. 19, n. 5, p. 407, doi. 10.1007/s13365-013-0208-4

By:

Mattson, Mark

Publication type:

Article

A Physically-Modified Saline Suppresses Neuronal Apoptosis, Attenuates Tau Phosphorylation and Protects Memory in an Animal Model of Alzheimer's Disease.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0103606

By:

Modi, Khushbu K.;
Jana, Arundhati;
Ghosh, Supurna;
Watson, Richard;
Pahan, Kalipada

Publication type:

Article

Aggregate-Depleted Brain Fails to Induce Aβ Deposition in a Mouse Model of Alzheimer's Disease.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089014

By:

Duran-Aniotz, Claudia;
Morales, Rodrigo;
Moreno-Gonzalez, Ines;
Hu, Ping Ping;
Fedynyshyn, Joseph;
Soto, Claudio

Publication type:

Article

A Shortened Barnes Maze Protocol Reveals Memory Deficits at 4-Months of Age in the Triple-Transgenic Mouse Model of Alzheimer's Disease.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080355

By:

Attar, Aida;
Liu, Tingyu;
Chan, Wai-Ting Coco;
Hayes, Jane;
Nejad, Mona;
Lei, KaiChyuan;
Bitan, Gal

Publication type:

Article

Selection of Appropriate Reference Genes for RT-qPCR Analysis in a Streptozotocin-Induced Alzheimer’s Disease Model of Cynomolgus Monkeys (<i>Macaca fascicularis</i>).

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056034

By:

Park, Sang-Je;
Kim, Young-Hyun;
Lee, Youngjeon;
Kim, Kyoung-Min;
Kim, Heui-Soo;
Lee, Sang-Rae;
Kim, Sun-Uk;
Kim, Sang-Hyun;
Kim, Ji-Su;
Jeong, Kang-Jin;
Lee, Kyoung-Min;
Huh, Jae-Won;
Chang, Kyu-Tae

Publication type:

Article

Immunomodulation Targeting Abnormal Protein Conformation Reduces Pathology in a Mouse Model of Alzheimer's Disease.

Published in:

PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013391

By:

Goñi, Fernando;
Prelli, Frances;
Yong Ji;
Scholtzova, Henrieta;
Jing Yang;
Yanjie Sun;
Feng-Xia Liang;
Kascsak, Regina;
Kascsak, Richard;
Mehta, Pankaj;
Wisniewski, Thomas

Publication type:

Article

Gender- and Age-Dependent γ-Secretase Activity in Mouse Brain and Its Implication in Sporadic Alzheimer Disease.

Published in:

PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005088

By:

Placanica, Lisa;
Lei Zhu;
Yue-Ming Li

Publication type:

Article

Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease.

Published in:

PLoS ONE, 2008, v. 3, n. 8, p. 1, doi. 10.1371/journal.pone.0002935

By:

Rodríguez1, José J.;
Jones, Victoria C.;
Tabuchi, Masashi;
Allan, Stuart M.;
Knight, Elysse M.;
LaFerla, Frank M.;
Oddo, Salvatore;
Verkhratsky, Alexei

Publication type:

Article

Reconsidering hippocampal neurogenesis in Alzheimer's disease.

Published in:

Frontiers in Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fnins.2014.00147

By:

Martinez-Canabal, Alonso

Publication type:

Article

Amyloid and tau pathology of familial Alzheimer's disease APP/PS1 mouse model in a senescence phenotype background (SAMP8).

Published in:

Age (0161-9152), 2015, v. 37, n. 1, p. 1, doi. 10.1007/s11357-015-9747-3

By:

Porquet, D.;
Andrés-Benito, P.;
Griñán-Ferré, C.;
Camins, A.;
Ferrer, I.;
Canudas, A. M.;
Del Valle, J.;
Pallàs, Mercè

Publication type:

Article

Age-dependent impairment of glucose tolerance in the 3xTg-AD mouse model of Alzheimer's disease.

Published in:

FASEB Journal, 2015, v. 29, n. 10, p. 4273, doi. 10.1096/fj.14-268482

By:

Vandal, Milene;
White, Phillip J.;
Chevrier, Geneviève;
Tremblay, Cyntia;
St.-Amour, Isabelle;
Planel, Emmanuel;
Marette, Andre;
Calon, Frederic

Publication type:

Article

Anxiolytic and antidepressant profile of the methanolic extract of Piper nigrum fruits in beta-amyloid (1-42) rat model of Alzheimer's disease.

Published in:

Behavioral & Brain Functions, 2015, v. 11, n. 1, p. 1, doi. 10.1186/s12993-015-0059-7

By:

Hritcu, Lucian;
Noumedem, Jaurès A.;
Cioanca, Oana;
Hancianu, Monica;
Postu, Paula;
Mihasan, Marius

Publication type:

Article

News.

Published in:: Chemistry & Industry, 2012, v. 76, n. 3, p. 6, doi. 10.1002/cind.7603_3.x
Publication type:: Article

Protective effect of telmisartan on neurovascular unit and inflammasome in stroke-resistant spontaneously hypertensive rats.

Published in:

Neurological Research, 2015, v. 37, n. 6, p. 491, doi. 10.1179/1743132815Y.0000000002

By:

Liu, Wentao;
Yamashita, Toru;
Kurata, Tomoko;
Kono, Syoichiro;
Hishikawa, Nozomi;
Deguchi, Kentaro;
Zhai, Yun;
Abe, Koji

Publication type:

Article

Asiaticoside ameliorates β-amyloid-induced learning and memory deficits in rats by inhibiting mitochondrial apoptosis and reducing inflammatory factors.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 13, n. 2, p. 413, doi. 10.3892/etm.2016.4004

By:

ZHUO ZHANG;
XIAOBIN LI;
DUO LI;
MAO LUO;
YONGJIE LI;
LI SONG;
XIAN JIANG

Publication type:

Article

Gastrodin alleviates memory deficits and reduces neuropathology in a mouse model of Alzheimer's disease.

Published in:

Neuropathology, 2014, v. 34, n. 4, p. 370, doi. 10.1111/neup.12115

By:

Hu, Yikui;
Li, Chengyan;
Shen, Wei

Publication type:

Article

The relationship between glycine transporter 1 occupancy and the effects of the glycine transporter 1 inhibitor RG1678 or ORG25935 on object retrieval performance in scopolamine impaired rhesus monkey.

Published in:

Psychopharmacology, 2014, v. 231, n. 3, p. 511, doi. 10.1007/s00213-013-3260-0

By:

Eddins, Donnie;
Hamill, Terence;
Puri, Vanita;
Cannon, Christopher;
Vivian, Jeffrey;
Sanabria-Bohórquez, Sandra;
Cook, Jacquelynn;
Morrow, John;
Thomson, Fiona;
Uslaner, Jason

Publication type:

Article

Effects of sub-chronic donepezil on brain Abeta and cognition in a mouse model of Alzheimer's disease.

Published in:

Psychopharmacology, 2013, v. 230, n. 2, p. 279, doi. 10.1007/s00213-013-3152-3

By:

Easton, Amy;
Sankaranarayanan, Sethu;
Tanghe, An;
Terwel, Dick;
Lin, Alan;
Hoque, Nina;
Bourin, Clotilde;
Gu, Huidong;
Ahlijanian, Michael;
Bristow, Linda

Publication type:

Article

Role of Notoginsenoside Rgl in Improving Spatial Cognitive Ability and Lowering Phosphorylation Level of Tau Protein in AD Model Rats.

Published in:

Medicinal Plant, 2018, v. 9, n. 2, p. 73, doi. 10.19600/j.cnki.issn2152-3924.2018.02.018

By:

Muzhe LI;
Wenhui WU;
Zhiping WU;
Meiling REN;
Shuxian CHEN;
Xiaoling GUO;
Ping WANG;
Li LIN

Publication type:

Article

Pharmacologic blockade of 12/15-lipoxygenase ameliorates memory deficits, Aβ and tau neuropathology in the triple-transgenic mice.

Published in:

Molecular Psychiatry, 2015, v. 20, n. 11, p. 1329, doi. 10.1038/mp.2014.170

By:

Chu, J;
Li, J-G;
Giannopoulos, P F;
Blass, B E;
Childers, W;
Abou-Gharbia, M;
Praticò, D

Publication type:

Article

DISC1 regulates trafficking and processing of APP and Aβ generation.

Published in:

Molecular Psychiatry, 2015, v. 20, n. 7, p. 874, doi. 10.1038/mp.2014.100

By:

Shahani, N;
Seshadri, S;
Jaaro-Peled, H;
Ishizuka, K;
Hirota-Tsuyada, Y;
Wang, Q;
Koga, M;
Sedlak, T W;
Korth, C;
Brandon, N J;
Kamiya, A;
Subramaniam, S;
Tomoda, T;
Sawa, A

Publication type:

Article

Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model.

Published in:

Frontiers in Aging Neuroscience, 2013, v. 5, p. 1, doi. 10.3389/fnagi.2013.00065

By:

Xiao-rui Cheng;
Xiu-liang Cui;
Yue Zheng;
Gui-rong Zhang;
Peng Li;
Huang Huang;
Yue-ying Zhao;
Wen-xia Zhou;
Yong-xiang Zhang

Publication type:

Article

Baicalein improves behavioral dysfunction induced by Alzheimer's disease in rats.

Published in:

Neuropsychiatric Disease & Treatment, 2016, v. 12, p. 3145, doi. 10.2147/ndt.s117469

By:

Li Zhou;
Sha Tan;
Yi-long Shan;
Yu-ge Wang;
Wei Cai;
Xue-hong Huang;
Xi-yuan Liao;
Hai-yan Li;
Lei Zhang;
Bing-jun Zhang;
Zheng-qi Lu

Publication type:

Article

Intracranial injection of PEG-PEI/ROCK II-siRNA improves cognitive impairment in a mouse model of Alzheimer's disease.

Published in:

International Journal of Neuroscience, 2014, v. 124, n. 9, p. 697, doi. 10.3109/00207454.2013.877014

By:

Wen, Xiaojun;
Wang, Limin;
Liu, Zhonglin;
Liu, Yunyun;
Hu, Jingyang

Publication type:

Article

Sominone Improves Memory Impairments and Increases Axonal Density in Alzheimer's Disease Model Mice, 5XFAD.

Published in:

International Journal of Neuroscience, 2011, v. 121, n. 4, p. 181, doi. 10.3109/00207454.2010.541571

By:

Joyashiki, Eri;
Matsuya, Yuji;
Tohda, Chihiro

Publication type:

Article

What is the new target inhibiting the progression of Alzheimer's disease?

Published in:

Neural Regeneration Research, 2013, v. 8, n. 21, p. 1938, doi. 10.3969/j.issn.1673-5374.2013.21.002

By:

Lin Zhang;
Jing Yang;
Yunpeng Cao

Publication type:

Article

Effect of p62 on tau hyperphosphorylation in a rat model of Alzheimer's disease.

Published in:

2012

By:

Xianhong Zheng;
Weiwei Wang;
Ruizhi Liu;
Honglan Huang;
Rihui Zhang;
Liankun Sun

Publication type:

Abstract

Buyuan Congnao decoction decreases hippocampal beta-amyloid expression in a rat model of Alzheimer's disease.

Published in:

Neural Regeneration Research, 2012, v. 7, n. 9, p. 664, doi. 10.3969/j.issn.1673-5374.2012.09.004

By:

Min Chen;
Jing Wang;
Cairong Ming

Publication type:

Article