The Effects of Eight Weeks of Rhythmic Exercises with Music on IGFBP-3 Levels, Insulin Resistance Index and Quality of Life in Women with Different Body Mass Indices.
Introduction: Inactivity and passive lifestyle have led to an increase in mortality and the incidence of chronic diseases such as hypertension, type 2 diabetes and obesity. The aim of this study was to investigate the effects of eight weeks of rhythmic exercises with music on IGFBP-3, insulin resistance index and quality of life in women with different body mass indices. Methods: In this quasi-experimental study, 33 sedentary women were randomly divided into three groups: exercise + normal)body mass index [BMI] 20 to 24.9 kg/m²) (n= 11), exercise + overweight (BMI 25 to 29.9 kg/m²) (n=11), and exercise + obese (BMI 30 to 34.9 kg/m²) (n=11). The rhythmic exercise program consisted of 8 weeks, three sessions per week and each session was performed for 45 to 60 minutes with an intensity equal to 60 to 70% HRmax. The paired t-test and one-way ANOVA with repeated measures were used to compare changes within and between groups. Results: The results showed that the time interaction in the groups in terms of IGFBP-3, insulin, glucose, insulin resistance and quality of life was not statistically significant. The results of the comparison of withingroup means showed that in the normal body mass index group, the overweight and obese groups, IGFBP-3 levels, quality of life have significantly increased. In the overweight and obese body mass index groups, serum insulin levels, glucose, and insulin resistance index significantly decreased. Conclusion(s): Rhythmic exercise increased IGFBP-3 concentration and decreased fasting glucose, fasting insulin, insulin resistance index in all three groups.