Works matching DE "INSULIN synthesis"

Results: 216

Cover Feature: Advanced Insulin Synthesis by One‐pot/Stepwise Disulfide Bond Formation Enabled by S‐Protected Cysteine Sulfoxide (Chem. Eur. J. 39/2024).

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 39, p. 1, doi. 10.1002/chem.202402230

By:

Hidaka, Kota;
Kobayashi, Daishiro;
Hayashi, Junya;
Denda, Masaya;
Otaka, Akira

Publication type:

Article

Advanced Insulin Synthesis by One‐pot/Stepwise Disulfide Bond Formation Enabled by S‐Protected Cysteine Sulfoxide.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 39, p. 1, doi. 10.1002/chem.202401003

By:

Hidaka, Kota;
Kobayashi, Daishiro;
Hayashi, Junya;
Denda, Masaya;
Otaka, Akira

Publication type:

Article

Characterization and optimization of two-chain folding pathways of insulin via native chain assembly.

Published in:

Communications Chemistry, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42004-018-0024-0

By:

Arai, Kenta;
Takei, Toshiki;
Shinozaki, Reina;
Noguchi, Masato;
Fujisawa, Shouta;
Katayama, Hidekazu;
Moroder, Luis;
Ando, Setsuko;
Okumura, Masaki;
Inaba, Kenji;
Hojo, Hironobu;
Iwaoka, Michio

Publication type:

Article

Impact of variants of the EXT2 gene on Type 2 diabetes and its related traits in the Chinese han population.

Published in:

Endocrine Research, 2015, v. 40, n. 2, p. 79, doi. 10.3109/07435800.2014.952015

By:

Ren, Qian;
Xiao, Jianzhong;
Han, Xueyao;
Yang, Wenying;
Ji, Linong

Publication type:

Article

Synthesis, Characterization, and Anti-Diabetic Therapeutic Activity of New Vanadyl(II) Complexes with Orotic Acid and Different Amino Acids Mixed Ligands.

Published in:

Russian Journal of General Chemistry, 2019, v. 89, n. 10, p. 2121, doi. 10.1134/S1070363219100219

By:

Al-Wasidi, A. S.;
Al-Jafshar, N. M.;
Al-Anazi, A. M.;
Refat, M. S.;
Ismail, L. A.;
Al-Omar, M. A.;
Naglah, A. M.;
Kalmouch, Atef

Publication type:

Article

β Cell and Autophagy: What Do We Know?

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 4, p. 649, doi. 10.3390/biom13040649

By:

Mohammadi-Motlagh, Hamid-Reza;
Sadeghalvad, Mona;
Yavari, Niloofar;
Primavera, Rosita;
Soltani, Setareh;
Chetty, Shashank;
Ganguly, Abantika;
Regmi, Shobha;
Fløyel, Tina;
Kaur, Simranjeet;
Mirza, Aashiq H.;
Thakor, Avnesh S.;
Pociot, Flemming;
Yarani, Reza

Publication type:

Article

Cholesterol Redistribution in Pancreatic β-Cells: A Flexible Path to Regulate Insulin Secretion.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 224, doi. 10.3390/biom13020224

By:

Galli, Alessandra;
Arunagiri, Anoop;
Dule, Nevia;
Castagna, Michela;
Marciani, Paola;
Perego, Carla

Publication type:

Article

Therapeutic Silencing of Centromere Protein X Ameliorates Hyperglycemia in Zebrafish and Mouse Models of Type 2 Diabetes Mellitus.

Published in:

Frontiers in Genetics, 2019, p. 1, doi. 10.3389/fgene.2019.00693

By:

Zang, Liqing;
Shimada, Yasuhito;
Nakayama, Hiroko;
Chen, Wenbiao;
Okamoto, Ayaka;
Koide, Hiroyuki;
Oku, Naoto;
Dewa, Takehisa;
Shiota, Masayuki;
Nishimura, Norihiro

Publication type:

Article

Local and regional control of calcium dynamics in the pancreatic islet.

Published in:

Diabetes, Obesity & Metabolism, 2017, v. 19, p. 30, doi. 10.1111/dom.12990

By:

Rutter, Guy A.;
Hodson, David J.;
Chabosseau, Pauline;
Haythorne, Elizabeth;
Pullen, Timothy J.;
Leclerc, Isabelle

Publication type:

Article

cAMP signalling in insulin and glucagon secretion.

Published in:

Diabetes, Obesity & Metabolism, 2017, v. 19, p. 42, doi. 10.1111/dom.12993

By:

Tengholm, Anders;
Gylfe, Erik

Publication type:

Article

The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance.

Published in:

Diabetes, Obesity & Metabolism, 2014, v. 16, n. 12, p. 1269, doi. 10.1111/dom.12357

By:

van Poppel, P. C. M.;
van Asseldonk, E. J. P.;
Holst, J. J.;
Vilsbøll, T.;
Netea, M. G.;
Tack, C. J.

Publication type:

Article

Adiponectin increases insulin content and cell proliferation in MIN6 cells via PPARγ-dependent and PPARγ-independent mechanisms.

Published in:

Diabetes, Obesity & Metabolism, 2012, v. 14, n. 11, p. 983, doi. 10.1111/j.1463-1326.2012.01626.x

By:

Rao, J. R.;
Keating, D. J.;
Chen, C.;
Parkington, H. C.

Publication type:

Article

Representation of insulin synthesis and construction of a three-dimensional insulin model as didactic tools in basic education.

Published in:

Journal of Biological Education (Taylor & Francis Ltd), 2024, v. 58, n. 2, p. 344, doi. 10.1080/00219266.2022.2058983

By:

Schmitz, Gabriela L.;
Joras, Luana E.;
Nogara, Pablo A.;
Galiciolli, Maria Eduarda A;
Piccoli, Bruna C.;
Davila da Silva, Fernanda;
Oliveira, Cláudia S.;
Rocha, João B. T.

Publication type:

Article

The Impact of Resistance and Aerobic Training on the Insulin Synthesis Genes Expression in Diabetic Rats.

Published in:

Iranian Journal of Diabetes & Obesity (IJDO), 2023, v. 15, n. 3, p. 190, doi. 10.18502/ijdo.v15i3.13740

By:

Ghofrani, Mohammad Hossein;
Rahimi, Alireza;
Alijani, Eidi;
Feizolahi, Foad

Publication type:

Article

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling.

Published in:

Science Signaling, 2019, v. 12, n. 593, p. 1, doi. 10.1126/scisignal.aav9150

By:

Mayer, Alexander E.;
Löffler, Mona C.;
Loza Valdés, Angel E.;
Schmitz, Werner;
El-Merahbi, Rabih;
Viera, Jonathan Trujillo;
Erk, Manuela;
Zhang, Thianzhou;
Braun, Ursula;
Heikenwalder, Mathias;
Leitges, Michael;
Schulze, Almut;
Sumara, Grzegorz

Publication type:

Article

Hepatic insulin synthesis increases in rat models of diabetes mellitus type 1 and 2 differently.

Published in:

PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0294432

By:

Abidov, Musa;
Sokolova, Ksenia;
Danilova, Irina;
Baykenova, Madina;
Gette, Irina;
Mychlynina, Elena;
Aydin Ozgur, Burcin;
Gurol, Ali Osman;
Yilmaz, M. Temel

Publication type:

Article

Naturally produced protein shows promise as a potential new target for diabetes treatment.

Published in:

Expert Review of Endocrinology & Metabolism, 2012, v. 7, n. 4, p. 374

By:

Laura McGuinness, Laura xz

Publication type:

Article

Chemerin as an Inducer of β Cell Proliferation Mediates Mitochondrial Homeostasis and Promotes β Cell Mass Expansion.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9136, doi. 10.3390/ijms24119136

By:

Li, Min;
Zhang, Ruifan;
Ge, Qian;
Yue, Lingzhi;
Ma, Dan;
Khattab, Firas;
Xie, Wenhua;
Cui, Yewei;
Gilon, Patrick;
Zhao, Xueya;
Li, Xi;
Cheng, Rui

Publication type:

Article

Evaluation of Insulin-Like Activity of Novel Zinc Metal–Organics toward Adipogenesis Signaling.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 6757, doi. 10.3390/ijms22136757

By:

Gabriel, Catherine;
Tsave, Olga;
Yavropoulou, Maria P.;
Architektonidis, Theodore;
Raptopoulou, Catherine P.;
Psycharis, Vassilis;
Salifoglou, Athanasios

Publication type:

Article

Role of Insulin in Health and Disease: An Update.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6403, doi. 10.3390/ijms22126403

By:

Rahman, Md Saidur;
Hossain, Khandkar Shaharina;
Das, Sharnali;
Kundu, Sushmita;
Adegoke, Elikanah Olusayo;
Rahman, Md. Ataur;
Hannan, Md. Abdul;
Uddin, Md Jamal;
Pang, Myung-Geol

Publication type:

Article

Pathophysiology of Type 2 Diabetes Mellitus.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6275, doi. 10.3390/ijms21176275

By:

Galicia-Garcia, Unai;
Benito-Vicente, Asier;
Jebari, Shifa;
Larrea-Sebal, Asier;
Siddiqi, Haziq;
Uribe, Kepa B.;
Ostolaza, Helena;
Martín, César

Publication type:

Article

Alpha-Mangostin Improves Insulin Secretion and Protects INS-1 Cells from Streptozotocin-Induced Damage.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 5, p. 1484, doi. 10.3390/ijms19051484

By:

Lee, Dahae;
Kim, Young-Mi;
Jung, Kiwon;
Chin, Young-Won;
Kang, Ki Sung

Publication type:

Article

A Synthetic Route to Human Insulin Using Isoacyl Peptides.

Published in:

Angewandte Chemie, 2014, v. 126, n. 15, p. 4064, doi. 10.1002/ange.201310735

By:

Liu, Fa;
Luo, Ethan Y.;
Flora, David B.;
Mezo, Adam R.

Publication type:

Article

Tropisetron improved testicular inflammation in the streptozotocin‐induced diabetic rats: The role of toll‐like receptor 4 (TLR4) and mir146a.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 3, p. 1, doi. 10.1002/jbt.23272

By:

Naderi, Roya;
Pourheydar, Bagher;
Moslehi, Azam

Publication type:

Article

Medium and copy number effects on the secretion of human proinsulin in Escherichia coli using the universal stress promoters uspA and uspB.

Published in:

Applied Microbiology & Biotechnology, 2003, v. 61, n. 5/6, p. 495, doi. 10.1007/s00253-003-1232-8

By:

Mergulhão, F. J. M.;
Monteiro, G. A.;
Larsson, G.;
Sandén, A. M.;
Farewell, A.;
Nystrom, T.;
Cabral, J. M. S.;
Taipa, M. A.

Publication type:

Article

Two-step transpeptidation of the insulin precursor expressed in Pichia pastoris to insulin ester via trypsin-catalyzed cleavage and coupling.

Published in:

Biotechnology & Applied Biochemistry, 2014, v. 61, n. 4, p. 408, doi. 10.1002/bab.1186

By:

Liu, Haifeng;
Zhou, Xiangshan;
Tian, Shousheng;
Hao, Xianghui;
You, Jinhua;
Zhang, Yuanxing

Publication type:

Article

Systolic Dysfunction of the Heart in Type 1 Diabetes Mellitus.

Published in:

Bulletin of Experimental Biology & Medicine, 2021, v. 172, n. 1, p. 14, doi. 10.1007/s10517-021-05321-1

By:

Lakomkin, V. L.;
Abramov, A. A.;
Lukoshkova, E. V.;
Prosvirnin, A. V.;
Kapelko, V. I.

Publication type:

Article

Generation of an Induced Pluripotent Stem Cell Line ERCi003-A Derived from a Patient with Maturity-Onset Diabetes of the Young Type 10 Caused by a Heterozygous INS Mutation.

Published in:

2024

By:

Bastrich, A. N.;
Antonov, D.;
Podzhilkova, A.;
Petrova, D. A.;
Pylina, S. V.;
Laptev, D. N.;
Sechko, E. A.;
Kuznetsov, S. N.;
Vetchinkina, E. A.;
Mokrysheva, N. G.

Publication type:

Case Study

Metabolic and endocrine changes associated with undernutrition in the peripubertal gilt1.

Published in:: Journal of Animal Science, 1993, v. 71, n. 7, p. 1887, doi. 10.2527/1993.7171887x
Publication type:: Article

Sitagliptin-induced pancreatitis - a longer road than expected.

Published in:

Clinical Case Reports, 2014, v. 2, n. 4, p. 149, doi. 10.1002/ccr3.83

By:

Nelson, Matthew;
Bhandari, Niyati;
Wener, Jill

Publication type:

Article

A Novel Three-Compartmental Model for Artificial Pancreas: Development and Validation.

Published in:

Artificial Organs, 2017, v. 41, n. 12, p. E326, doi. 10.1111/aor.12980

By:

Piemonte, Vincenzo;
Capocelli, Mauro;
De Santis, Luca;
Maurizi, Anna Rita;
Pozzilli, Paolo

Publication type:

Article

CRISPR/Cas9-Mediated α-ENaC Knockout in a Murine Pancreatic β-Cell Line.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.664799

By:

Zhang, Xue;
Zhao, Lihua;
Jin, Runbing;
Li, Min;
Li, Mei-Shuang;
Li, Rongfeng;
Liang, Xiubin

Publication type:

Article

The long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24302-6

By:

Zhang, Fangfang;
Yang, Yue;
Chen, Xi;
Liu, Yue;
Hu, Qianxing;
Huang, Bin;
Liu, Yuhong;
Pan, Yi;
Zhang, Yanfeng;
Liu, Dechen;
Liang, Rui;
Li, Guoqing;
Wei, Qiong;
Li, Ling;
Jin, Liang

Publication type:

Article

Beta-Cell Adaptation to Pregnancy – Role of Calcium Dynamics.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.853876

By:

Pretorius, Marle;
Huang, Carol

Publication type:

Article

Chop/Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice.

Published in:

Science Translational Medicine, 2021, v. 13, n. 604, p. 1, doi. 10.1126/scitranslmed.aba9796

By:

Yong, Jing;
Parekh, Vishal S.;
Reilly, Shannon M.;
Nayak, Jonamani;
Chen, Zhouji;
Lebeaupin, Cynthia;
Jang, Insook;
Zhang, Jiangwei;
Prakash, Thazha P.;
Sun, Hong;
Murray, Sue;
Guo, Shuling;
Ayala, Julio E.;
Satin, Leslie S.;
Saltiel, Alan R.;
Kaufman, Randal J.

Publication type:

Article

Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery.

Published in:

Polymers (20734360), 2024, v. 16, n. 4, p. 510, doi. 10.3390/polym16040510

By:

Jamshidnejad-Tosaramandani, Tahereh;
Kashanian, Soheila;
Karimi, Isaac;
Schiöth, Helgi B.

Publication type:

Article

Genetic, Functional, and Immunological Study of ZnT8 in Diabetes.

Published in:

International Journal of Endocrinology, 2019, p. 1, doi. 10.1155/2019/1524905

By:

Huang, Qiong;
Du, Jie;
Merriman, Chengfeng;
Gong, Zhicheng

Publication type:

Article

Association between immunity and different clinical symptoms in patients with polycystic ovary syndrome.

Published in:

American Journal of Reproductive Immunology, 2023, v. 90, n. 4, p. 1, doi. 10.1111/aji.13780

By:

Xiao, Huan;
Yin, Tailang;
Diao, Lianghui;
Zhang, Yan;
Huang, Chunyu

Publication type:

Article

A different kind of synthesis: artificial synthesis of insulin in socialist China.

Published in:

History & Technology, 2019, v. 35, n. 4, p. 453, doi. 10.1080/07341512.2019.1694124

By:

Ling, Vivian;
Jiang, Lijing

Publication type:

Article

Chemical Synthesis of a Fluorescent IGF-II Analogue.

Published in:

International Journal of Peptide Research & Therapeutics, 2013, v. 19, n. 1, p. 61, doi. 10.1007/s10989-012-9339-3

By:

Cottam, Jade;
Scanlon, Denis;
Karas, John;
Calabrese, Antonio;
Pukala, Tara;
Forbes, Briony;
Wallace, John;
Abell, Andrew

Publication type:

Article

OVEREXPRESSION OF PTEN GENE INCREASES INS2 GENE mRNA EXPRESSION, NOT INS1 GENE mRNA EXPRESSION, IN INSULINOMA CELL LINE RIN-5F.

Published in:

Acta Endocrinologica (1841-0987), 2023, v. 19, n. 3, p. 277, doi. 10.4183/aeb.2023.277

By:

Kiba, T.

Publication type:

Article

Melatonin heals the gut.

Published in:

2014

By:

Eliasson, L.

Publication type:

Editorial

Placental small extracellular vesicles from normal pregnancy and gestational diabetes increase insulin gene transcription and content in β cells.

Published in:

Clinical Science, 2024, v. 138, n. 22, p. 1481, doi. 10.1042/CS20241782

By:

Seedat, Faheem;
Kandzija, Neva;
Ellis, Michael J.;
Shuhan Jiang;
Sarbalina, Asselzhan;
Bancroft, James;
Drydale, Edward;
Hester, Svenja S.;
Fischer, Roman;
Wade, Alisha N.;
Stefana, M. Irina;
Todd, John A.;
Vatish, Manu

Publication type:

Article

Highly perturbed genes and hub genes associated with type 2 diabetes in different tissues of adult humans: a bioinformatics analytic workflow.

Published in:

Functional & Integrative Genomics, 2022, v. 22, n. 5, p. 1003, doi. 10.1007/s10142-022-00881-5

By:

De Silva, Kushan;
Demmer, Ryan T.;
Jönsson, Daniel;
Mousa, Aya;
Forbes, Andrew;
Enticott, Joanne

Publication type:

Article

Downregulation of Kcnq1ot1 attenuates β-cell proliferation and insulin secretion via the miR-15b-5p/Ccnd1 and Ccnd2 axis.

Published in:

Acta Diabetologica, 2022, v. 59, n. 7, p. 885, doi. 10.1007/s00592-022-01871-6

By:

Li, Yanli;
Chen, Yalan;
Liu, Ziyu;
Lin, Beisi;
Deng, Xiaoyi;
Xiao, Qiwen;
Chen, Zhishan;
Ye, Huiyu;
Chen, Danrui;
Su, Yanna;
Li, Wangen;
Xu, Wen

Publication type:

Article

Association of additive risk of INC I gene with the presence of Diabetes Type 1 and Type 2.

Published in:

International Journal of Pharmaceutical Research (09752366), 2021, v. 13, n. 1, p. 3580, doi. 10.31838/ijpr/2021.13.01.574

By:

AL-SALIH, AWS RASSUL HUSSAIN

Publication type:

Article

Effects of High-Intensity Interval Training on Transcription Factor 7-Like 2 / Glucagon-Like Peptide-1 Axis in Pancreatic Tissue of Obese Diabetic Rats.

Published in:

Medical Laboratory Journal, 2023, v. 17, n. 3, p. 15, doi. 10.29252/mlj.17.3.15

By:

Mehdi Behkar;
Mojtaba Eizadi;
Saeid Sedaghaty;
Yaser Kazemzadeh;
Motahareh Moslehi

Publication type:

Article

Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome.

Published in:

Biomedicines, 2025, v. 13, n. 1, p. 212, doi. 10.3390/biomedicines13010212

By:

Soukop, Jan;
Kazdová, Ludmila;
Hüttl, Martina;
Malínská, Hana;
Marková, Irena;
Oliyarnyk, Olena;
Miklánková, Denisa;
Gurská, Soňa;
Rácová, Zuzana;
Poruba, Martin;
Večeřa, Rostislav

Publication type:

Article

Metformin restores prohormone processing enzymes and normalizes aberrations in secretion of proinsulin and insulin in palmitate‐exposed human islets.

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 12, p. 3757, doi. 10.1111/dom.15270

By:

Wen, Quan;
Chowdhury, Azazul Islam;
Aydin, Banu;
Shekha, Mudhir;
Stenlid, Rasmus;
Forslund, Anders;
Bergsten, Peter

Publication type:

Article

Efficacy and Tolerability of Pioglitazone in Patients with Type 2 Diabetes Mellitus: Comparison with Other Oral Antihyperglycaemic Agents.

Published in:: Drugs, 2010, v. 70, n. 15, p. 1945, doi. 10.2165/11538100-000000000-00000
Publication type:: Article