Works matching DE "INSULIN pharmacokinetics"

Results: 120

Beware the pitfalls of time below range.

Published in:

Diabetic Medicine, 2023, v. 40, n. 11, p. 1, doi. 10.1111/dme.15124

By:

Thabit, Hood;
Schofield, Jonathan;
Leelarathna, Lalantha

Publication type:

Article

Optimal prandial timing of bolus insulin in diabetes management: a review.

Published in:

Diabetic Medicine, 2018, v. 35, n. 3, p. 306, doi. 10.1111/dme.13525

By:

Slattery, D.;
Amiel, S. A.;
Choudhary, P.

Publication type:

Article

Insulin degludec overdose may lead to long‐lasting hypoglycaemia through its markedly prolonged half‐life.

Published in:

Diabetic Medicine, 2018, v. 35, n. 2, p. 277, doi. 10.1111/dme.13557

By:

Uchida, J.;
Oikawa, Y.;
Katsuki, T.;
Takeda, H.;
Shimada, A.;
Kawai, T.

Publication type:

Article

Role of incretin-based therapies and sodium-glucose co-transporter-2 inhibitors as adjuncts to insulin therapy in Type 2 diabetes, with special reference to IDegLira.

Published in:

Diabetic Medicine, 2016, v. 33, n. 7, p. 864, doi. 10.1111/dme.13021

By:

Wilding, J. P. H.;
Bain, S. C.

Publication type:

Article

Insulin Glargine/Lixisenatide: A Review in Type 2 Diabetes.

Published in:

Drugs, 2017, v. 77, n. 12, p. 1353, doi. 10.1007/s40265-017-0783-4

By:

Scott, Lesley

Publication type:

Article

Insulin Glargine 300 U/mL: A Review in Diabetes Mellitus.

Published in:

Drugs, 2016, v. 76, n. 3, p. 363, doi. 10.1007/s40265-016-0541-z

By:

Blair, Hannah;
Keating, Gillian

Publication type:

Article

Insulin Aspart in the Management of Diabetes Mellitus: 15 Years of Clinical Experience.

Published in:

Drugs, 2016, v. 76, n. 1, p. 41, doi. 10.1007/s40265-015-0500-0

By:

Hermansen, Kjeld;
Bohl, Mette;
Schioldan, Anne

Publication type:

Article

Management of Diabetes Mellitus with Insulin Lispro.

Published in:

Clinical Medicine Insights: Therapeutics, 2011, n. 3, p. 275, doi. 10.4137/CMT.S1155

By:

Tanaka, Masami;
Itoh, Hiroshi

Publication type:

Article

Toward Better Understanding of Insulin Therapy by Translation of a PK‐PD Model to Visualize Insulin and Glucose Action Profiles.

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, n. 2, p. 258, doi. 10.1002/jcph.1321

By:

Schneck, Karen;
Tham, Lai San;
Ertekin, Ali;
Reviriego, Jesus

Publication type:

Article

Mechanism of action in dogs of slow-acting insulin analog O346.

Published in:

2003

By:

Ellmerer, Martin;
Hamilton-Wessler, Marianthe;
Kim, Stella P;
Dea, Melvin K;
Kirkman, Erlinda;
Perianayagam, Anjana;
Markussen, Jan;
Bergman, Richard N

Publication type:

journal article

Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry.

Published in:

Science Signaling, 2015, v. 8, n. 380, p. 1, doi. 10.1126/scisignal.aaa3139

By:

Parker, Benjamin L.;
Guang Yang;
Chaudhuri, Rima;
Xiuquan Ma;
James, David E.;
Humphrey, Sean J.;
Peterman, Scott

Publication type:

Article

Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients.

Published in:

2016

By:

van Vught, Lonneke A.;
Scicluna, Brendon P.;
Hoogendijk, Arie J.;
Wiewel, Maryse A.;
Klein Klouwenberg, Peter M. C.;
Cremer, Olaf L.;
Horn, Janneke;
Nürnberg, Peter;
Bonten, Marc M. J.;
Schultz, Marcus J.;
van der Poll, Tom

Publication type:

journal article

Kinetics-Effect Relations of Insulin-Releasing Drugs inPatients With Type 2 Diabetes.

Published in:

Diabetes, 2004, v. 53, p. S151, doi. 10.2337/diabetes.53.suppl_3.S151

By:

Melander, Arne

Publication type:

Article

An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures.

Published in:

2003

By:

Bennett, Robert G.;
Hamel, Frederick G.;
Duckworth, William C.

Publication type:

journal article

Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro.

Published in:

2000

By:

Lepore, Mauro;
Fanelli, Carmine;
Porcellati, Francesca;
Bartocci, Linda;
Di Vincenzo, Antonio;
Cordoni, Cristina;
Costa, Emanuela;
Brunetti, Paolo;
Bolli, Geremia B.;
Lepore, M;
Pampanelli, S;
Fanelli, C;
Porcellati, F;
Bartocci, L;
Di Vincenzo, A;
Cordoni, C;
Costa, E;
Brunetti, P;
Bolli, G B

Publication type:

journal article

Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients.

Published in:

2000

By:

Ryysy, Leena;
Hakkinen, Anna-Maija;
Goto, Takashi;
Vehkavaara, Satu;
Westerbacka, Jukka;
Halavaara, Juha;
Yki-Jarvinen, Hannele;
Ryysy, L;
Häkkinen, A M;
Goto, T;
Vehkavaara, S;
Westerbacka, J;
Halavaara, J;
Yki-Järvinen, H

Publication type:

journal article

Free fatty acids impair hepatic insulin extraction in vivo.

Published in:

1999

By:

Wiesenthal, Stephanie R.;
Sandhu, Harmanjit;
McCall, Richard H.;
Tchipashvili, Vaja;
Yoshii, Hidenori;
Polonsky, Kenneth;
Shi, Zed Q.;
Lewis, Gary F.;
Mari, Andrea;
Giacca, Adria;
Wiesenthal, S R;
Sandhu, H;
McCall, R H;
Tchipashvili, V;
Yoshii, H;
Polonsky, K;
Shi, Z Q;
Lewis, G F;
Mari, A;
Giacca, A

Publication type:

journal article

[Lys(B28), Pro(B29)]-human insulin. A rapidly absorbed analogue of human insulin.

Published in:

1994

By:

Howey, Daniel C.;
Bowsher, Ronald R.;
Brunelle, Rocco L.;
Woodworth, James R.;
Howey, D C;
Bowsher, R R;
Brunelle, R L;
Woodworth, J R

Publication type:

journal article

The pharmacodynamics and activity of intranasally administered insulin in healthy male volunteers.

Published in:

1993

By:

Jacobs, Maarten A. J. M.;
Schreuder, Robien H.;
Jap-A-Joe, Kenneth;
Nauta, Jos J.;
Andersen, Peder M.;
Heine, Robert J.;
Jacobs, M A;
Schreuder, R H;
Jap-A-Joe, K;
Nauta, J J;
Andersen, P M;
Heine, R J

Publication type:

journal article

In vivo imaging of insulin receptors in monkeys using 18F-labeled insulin and positron emission tomography.

Published in:

1992

By:

Eastman, Richard C.;
Carson, Richard E.;
Jacobson, Kenneth A.;
Shai, Yechial;
Channing, Michael A.;
Dunn, Bonnie B.;
Bacher, John D.;
Baas, Ervin;
Jones, Estelle;
Kirk, Kenneth L.;
Lesniak, Maxine A.;
Roth, Jesse;
Eastman, R C;
Carson, R E;
Jacobson, K A;
Shai, Y;
Channing, M A;
Dunn, B B;
Bacher, J D;
Baas, E

Publication type:

journal article

Scintigraphic studies in rats. Kinetics of insulin analogues covering wide range of receptor affinities.

Published in:

1991

By:

Jensen, I;
Kruse, V;
Larsen, U D

Publication type:

journal article

Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening.

Published in:

Assay & Drug Development Technologies, 2016, v. 14, n. 3, p. 180, doi. 10.1089/adt.2016.708

By:

Engen, Karin;
Rosenström, Ulrika;
Axelsson, Hanna;
Konda, Vivek;
Dahllund, Leif;
Otrocka, Magdalena;
Sigmundsson, Kristmundur;
Nikolaou, Alexandros;
Vauquelin, Georges;
Hallberg, Mathias;
Jenmalm Jensen, Annika;
Lundbäck, Thomas;
Larhed, Mats

Publication type:

Article

Characteristics and practicalities of a new basal insulin.

Published in:

British Journal of Nursing, 2014, v. 23, n. 1, p. 16, doi. 10.12968/bjon.2014.23.1.16

By:

Stockley, Susan

Publication type:

Article

In pursuit of excellence in diabetes care: trends in insulin delivery.

Published in:

British Journal of Nursing, 2012, v. 21, n. 10, p. 588, doi. 10.12968/bjon.2012.21.10.588

By:

Meetoo, Danny;
McAllister, Gillian;
West, Adele;
Turnbull, Mandy

Publication type:

Article

Pharmacokinetic Properties of Once‐Weekly Insulin Icodec in Children and Adolescents With Type 2 Diabetes.

Published in:

Pediatric Diabetes, 2025, v. 2025, p. 1, doi. 10.1155/pedi/5514927

By:

Van Name, Michelle;
Ásbjörnsdóttir, Björg;
Gomes, Mikel Murphy;
Hale, Paula M.;
Udupa, Keerthana;
Vinther, Siri;
Wolf, Risa M.;
Ribel-Madsen, Rasmus;
Scaramuzza, Andrea

Publication type:

Article

20 Years of insulin lispro in pediatric type 1 diabetes: a review of available evidence.

Published in:

Pediatric Diabetes, 2017, v. 18, n. 2, p. 81, doi. 10.1111/pedi.12401

By:

Kaiserman, Kevin;
Jung, Heike;
Benabbad, Imane;
Karges, Beate;
Polak, Michel;
Rosilio, Myriam

Publication type:

Article

Pharmacokinetic and prandial pharmacodynamic properties of insulin degludec/insulin aspart in children, adolescents, and adults with type 1 diabetes.

Published in:

Pediatric Diabetes, 2016, v. 17, n. 8, p. 642, doi. 10.1111/pedi.12358

By:

Biester, Torben;
Danne, Thomas;
Bläsig, Sarah;
Remus, Kerstin;
Aschemeier, Bärbel;
Kordonouri, Olga;
Bardtrum, Lars;
Haahr, Hanne

Publication type:

Article

Insulin degludec's ultra-long pharmacokinetic properties observed in adults are retained in children and adolescents with type 1 diabetes.

Published in:

Pediatric Diabetes, 2014, v. 15, n. 1, p. 27, doi. 10.1111/pedi.12116

By:

Biester, Torben;
Blaesig, Sarah;
Remus, Kerstin;
Aschemeier, Bärbel;
Kordonouri, Olga;
Granhall, Charlotte;
Søndergaard, Flemming;
Kristensen, Niels Rode;
Haahr, Hanne;
Danne, Thomas

Publication type:

Article

Faster pharmacokinetics and increased patient acceptance of intradermal insulin delivery using a single hollow microneedle in children and adolescents with type 1 diabetes.

Published in:

Pediatric Diabetes, 2013, v. 14, n. 6, p. 459, doi. 10.1111/pedi.12031

By:

Norman, James J;
Brown, Milton R;
Raviele, Nicholas A;
Prausnitz, Mark R;
Felner, Eric I

Publication type:

Article

Immunogenicity of different brands of human insulin and rapid-acting insulin analogs in insulin-naïve children with type 1 diabetes.

Published in:

Pediatric Diabetes, 2011, v. 12, n. 2, p. 78, doi. 10.1111/j.1399-5448.2010.00659.x

By:

Mianowska, B.;
Szadkowska, A.;
Pietrzak, I.;
Zmysłowska, A.;
Wegner, O.;
Tomczonek, J.;
Bodalski, J.;
Młynarski, W.

Publication type:

Article

Pharmacokinetic interactions with thiazolidinediones.

Published in:

2007

By:

Scheen, André J.;
Scheen, André J

Publication type:

journal article

Transdermal drug delivery of insulin with ultradeformable carriers.

Published in:

2003

By:

Cevc, Gregor

Publication type:

journal article

Maternal-fetal transport of hypoglycaemic drugs.

Published in:

2003

By:

Garcia-Bournissen, Facundo;
Feig, Denice S.;
Koren, Gideon

Publication type:

journal article

Clinical pharmacokinetics and pharmacodynamics of insulin lispro mixtures.

Published in:

2002

By:

Roach, P.;
Woodworth, J.R.;
Roach, Paris;
Woodworth, James R

Publication type:

journal article

Hyperglycemia in the Hospital Setting.

Published in:

MEDSURG Nursing, 2016, v. 25, n. 6, p. 393

By:

Freeland, Barbara

Publication type:

Article

Human insulin analog insulin aspart does not cause insulin allergy.

Published in:

2001

By:

Yasuda, Hisafumi;
Nagata, Masao;
Moriyama, Hiroaki;
Fujira, Kazuhiro;
Kotani, Reiko;
Yamada, Katsumi;
Ueda, Hiroo;
Yokono, Koichi;
Yasuda, H;
Nagata, M;
Moriyama, H;
Fujihira, K;
Kotani, R;
Yamada, K;
Ueda, H;
Yokono, K

Publication type:

Case Study

Insulin Aspart (B28 Asp-Insulin): A Fast-Acting Analog of Human Insulin.

Published in:

Diabetes Care, 1999, v. 22, n. 9, p. 1501, doi. 10.2337/diacare.22.9.1501

By:

Mudaliar, Sunder R.;
Lindberg, Fedon A.;
Joyce, Mary;
Beerdsen, Patricia;
Strange, Poul;
Lin, Alan;
Henry, Robert A.

Publication type:

Article

Insulin Response to Intravenous Glucose Correlates With Plasma Levels of the Tumor Necrosis Factor Receptor-1.

Published in:

Diabetes Care, 1999, v. 22, n. 5, p. 868, doi. 10.2337/diacare.22.5.868

By:

Fernandez-Real, Jose-Manuel;
Gutierrez, Cristina;
Broch, Montserrat;
Casamitjana, Roser;
Vendrell, Joan;
Ricart, Wilfredo;
Winkler, Gabor;
Lakatos, Peter;
Speer, Gabor;
Baranyi, Eva;
Melczer, Zsolt;
Cseh, Karoly

Publication type:

Article

Local skin-fold thickness as a clinical predictor of depot size during basal rate infusion of insulin.

Published in:

1993

By:

HILDEBRANDT, PER R.;
VAAG, ALLAN A.;
Hildebrandt, P R;
Vaag, A A

Publication type:

journal article

The absorption of subcutaneously injected short-acting soluble insulin: influence of injection technique and concentration.

Published in:

1983

By:

HILDEBRANDT, PER;
SESTOFT, LEIF;
NIELSEN, STEEN L.;
Hildebrandt, P;
Sestoft, L;
Nielsen, S L

Publication type:

journal article

Absorption kinetics and biologic effects of subcutaneously injected insulin preparations.

Published in:

1982

By:

Berger, M.;
Cüppers, H. J.;
Hegner, H.;
Jörgens, V.;
Berchtold, P.;
Cüppers, H J;
Jörgens, V

Publication type:

journal article

Analysis of PK/PD risk factors for development of type 2 diabetes in high risk population using Bayesian analysis of glucose–insulin kinetics.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2009, v. 36, n. 5, p. 421, doi. 10.1007/s10928-009-9130-z

By:

Chih-Wei Lin;
Peter Veng-Pedersen

Publication type:

Article

Insulin degludec: a new insulin for today?

Published in:

Diabetic Medicine, 2013, v. 30, n. 11, p. 1267, doi. 10.1111/dme.12319

By:

Hitman, G. A.

Publication type:

Article

Insulin degludec improves glycaemic control with lower nocturnal hypoglycaemia risk than insulin glargine in basal-bolus treatment with mealtime insulin aspart in Type 1 diabetes (BEGIN<sup>®</sup> Basal-Bolus Type 1): 2-year results of a randomized clinical trial

Published in:

Diabetic Medicine, 2013, v. 30, n. 11, p. 1293, doi. 10.1111/dme.12243

By:

Bode, B. W.;
Buse, J. B.;
Fisher, M.;
Garg, S. K.;
Marre, M.;
Merker, L.;
Renard, E.;
Russell‐Jones, D. L.;
Hansen, C. T.;
Rana, A.;
Heller, S. R.

Publication type:

Article

Acute hepatic injury following treatment of a long-acting insulin analogue overdose necessitating urgent insulin depot excision.

Published in:

Diabetic Medicine, 2012, v. 29, n. 2, p. 232, doi. 10.1111/j.1464-5491.2011.03385.x

By:

Warriner, D.;
Debono, M.;
Gandhi, R. A.;
Chong, E.;
Creagh, F.

Publication type:

Article

Diabetes mellitus: Its differentiation into insulin-sensitive and insulin-insensitive types.

Published in:

Diabetic Medicine, 2011, v. 28, n. 12, p. 1440, doi. 10.1111/j.1464-5491.2011.3508.x

By:

Himsworth, H. P.

Publication type:

Article

Serum omentin-1 and chemerin levels are interrelated in patients with Type 2 diabetes mellitus with or without ischaemic heart disease.

Published in:

Diabetic Medicine, 2011, v. 28, n. 10, p. 1194, doi. 10.1111/j.1464-5491.2011.03353.x

By:

El-Mesallamy, H. O.;
El-Derany, M. O.;
Hamdy, N. M.

Publication type:

Article

Type 2 diabetes mellitus and risk of malignancy: is there a strategy to identify a subphenotype of patients with increased susceptibility to endogenous and exogenous hyperinsulinism?

Published in:

Diabetic Medicine, 2011, v. 28, n. 3, p. 276, doi. 10.1111/j.1464-5491.2010.03132.x

By:

Müssig, K.;
Staiger, H.;
Kantartzis, K.;
Fritsche, A.;
Kanz, L.;
Häring, H.-U.

Publication type:

Article

Pharmacokinetics and pharmacodynamics of different modes of insulin pump delivery. A randomized, controlled study comparing subcutaneous and intravenous administration of insulin aspart.

Published in:

Diabetic Medicine, 2011, v. 28, n. 2, p. 230, doi. 10.1111/j.1464-5491.2010.03149.x

By:

Ihlo, C. A.;
Lauritzen, T.;
Sturis, J.;
Skyggebjerg, O.;
Christiansen, J. S.;
Laursen, T.

Publication type:

Article

Impact of pre-exercise rapid-acting insulin reductions on ketogenesis following running in Type 1 diabetes.

Published in:

Diabetic Medicine, 2011, v. 28, n. 2, p. 218, doi. 10.1111/j.1464-5491.2010.03162.x

By:

Bracken, R. M.;
West, D. J.;
Stephens, J. W.;
Kilduff, L. P.;
Luzio, S.;
Bain, S. C.

Publication type:

Article