Works matching Pharmacodynamics
Results: 5000
Role of mechanistically-based pharmacokinetic/pharmacodynamic models in drug development : a case study of a therapeutic protein.
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- 2006
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- journal article
Pharmacokinetic/pharmacodynamic modelling of antibacterials in vitro and in vivo using bacterial growth and kill kinetics: the minimum inhibitory concentration versus stationary concentration.
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- 2005
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- journal article
Pharmacokinetic-pharmacodynamic relationships of apomorphine in patients with Parkinson's disease.
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- 1999
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- journal article
Achieving an optimal outcome in the treatment of infections. The role of clinical pharmacokinetics and pharmacodynamics of antimicrobials.
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- 1999
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- journal article
Methodological issues in pharmacokinetic-pharmacodynamic modelling.
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- 1998
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- journal article
Pharmacokinetics and Pharmacodynamics of Newer Oral Cephalosporins: Implications for Treatment of Community-Acquired Lower Respiratory Tract Infections.
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- Clinical Drug Investigation, 1998, v. 16, n. 4, p. 335, doi. 10.2165/00044011-199816040-00008
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- Article
The pharmacokinetic-pharmacodynamic model of telmisartan and hydrochlorothiazide on blood pressure and plasma potassium after long-term administration in spontaneously hypertensive rats.
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- Fundamental & Clinical Pharmacology, 2015, v. 29, n. 6, p. 543, doi. 10.1111/fcp.12152
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- Article
A direct comparison of the pharmacodynamic properties of insulin detemir and neutral protamine lispro insulin in patients with type 1 diabetes A direct comparison of the pharmacodynamic properties of insulin detemir and neutral protamine lispro insulin in patients with type 1 diabetes
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- Diabetes, Obesity & Metabolism, 2013, v. 15, n. 3, p. 241, doi. 10.1111/dom.12016
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- Article
Population pharmacokinetics and pharmacodynamics of meropenem in Japanese pediatric patients.
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- Journal of Infection & Chemotherapy (Springer Science & Business Media B.V.), 2010, v. 16, n. 2, p. 139, doi. 10.1007/s10156-009-0025-0
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- Article
Characterization of Neutropenia in Advanced Cancer Patients Following Palbociclib Treatment Using a Population Pharmacokinetic-Pharmacodynamic Modeling and Simulation Approach.
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- Journal of Clinical Pharmacology, 2017, v. 57, n. 9, p. 1159, doi. 10.1002/jcph.902
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- Article
Plasma and cerebrospinal fluid concentrations of ibuprofen in pediatric patients and antipyretic effect: Pharmacokinetic-pharmacodynamic modeling analysis.
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- Journal of Clinical Pharmacology, 2014, v. 54, n. 9, p. 1023, doi. 10.1002/jcph.307
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- Article
Population pharmacokinetic and pharmacodynamic modeling of different formulations of ONO-5334, cathepsin K inhibitor, in Caucasian and Japanese postmenopausal females.
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- Journal of Clinical Pharmacology, 2014, v. 54, n. 1, p. 23, doi. 10.1002/jcph.186
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- Article
Population Pharmacokinetic and Pharmacodynamic Model-Based Comparability Assessment of a Recombinant Human Epoetin Alfa and the Biosimilar HX575.
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- Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1624, doi. 10.1177/0091270011421911
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Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Predict the Impact of CYP2C9 Genetic Polymorphisms, Co-Medication and Formulation on the Pharmacokinetics and Pharmacodynamics of Flurbiprofen.
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- Pharmaceutics, 2020, v. 12, n. 11, p. 1049, doi. 10.3390/pharmaceutics12111049
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- Article
Population pharmacokinetic-pharmacodynamic modelling to describe the effects of paracetamol and N-acetylcysteine on the international normalized ratio.
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- Clinical & Experimental Pharmacology & Physiology, 2015, v. 42, n. 1, p. 102, doi. 10.1111/1440-1681.12327
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Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects.
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- British Journal of Clinical Pharmacology, 2013, v. 75, n. 1, p. 197, doi. 10.1111/j.1365-2125.2012.04320.x
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Lamotrigine pharmacokinetic/pharmacodynamic modelling in rats.
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- Fundamental & Clinical Pharmacology, 2005, v. 19, n. 6, p. 669, doi. 10.1111/j.1472-8206.2005.00380.x
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Pharmacodynamic model of dopamine D1 receptor agonists in the treatment of breast cancer lung metastasis.
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- Journal of Chinese Pharmaceutical Sciences, 2020, v. 29, n. 1, p. 45, doi. 10.5246/jcps.2020.01.004
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- Article
Mechanism-based pharmacokinetic/pharmacodynamic modeling of the effects of sitagliptin on DPP-4 activity, insulin and glucose in diabetic rats.
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- Journal of Chinese Pharmaceutical Sciences, 2018, v. 27, n. 6, p. 371, doi. 10.5246/jcps.2018.06.038
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A strategy for designing voriconazole dosage regimens to prevent invasive pulmonary aspergillosis based on a cellular pharmacokinetics/pharmacodynamics model.
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- 2018
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- Publication type:
- journal article
Evaluation of the safety, pharmacodynamic, and pharmacokinetic effects following oral coadministration of immediate-release morphine with ethanol in healthy male participants.
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- Human Psychopharmacology: Clinical & Experimental, 2014, v. 29, n. 3, p. 251, doi. 10.1002/hup.2394
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Pharmacokinetic and pharmacodynamic assessments of atogepant in healthy male adults: Results from phase 1 studies.
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- Cephalalgia Reports, 2023, v. 6, p. 1, doi. 10.1177/25158163231191582
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Influence of aprepitant on the pharmacodynamics and pharmacokinetics of gliclazide in rats and rabbits.
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- PeerJ, 2018, v. 6, p. 1, doi. 10.7717/peerj.4798
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Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility.
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- European Biophysics Journal, 2004, v. 33, n. 8, p. 694, doi. 10.1007/s00249-004-0413-4
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Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Integration of Enrofloxacin Following Single Oral Administration of Different Doses in Brown Trout (Salmo trutta).
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- Animals (2076-2615), 2021, v. 11, n. 11, p. 3086, doi. 10.3390/ani11113086
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Pharmacokinetics, pharmacodynamics and drug interaction potential of enfuvirtide.
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- 2005
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- journal article
Pharmacodynamics of vancomycin and other antimicrobials in patients with Staphylococcus aureus lower respiratory tract infections.
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- 2004
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- journal article
Influence of severe renal impairment on the pharmacokinetics and pharmacodynamics of oral ximelagatran and subcutaneous melagatran.
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- 2003
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- journal article
Pharmacokinetic-Pharmacodynamic Relationships of Immunoglobulin Therapy for Envenomation.
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- Clinical Pharmacokinetics, 2003, v. 42, n. 8, p. 721
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Influence of age on the pharmacokinetics and pharmacodynamics of ximelagatran, an oral direct thrombin inhibitor.
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- 2003
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- journal article
Pharmacokinetics and pharmacodynamics of methotrexate in non-neoplastic diseases.
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- 2003
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Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease.
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- 2002
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- journal article
Clinical pharmacokinetics and pharmacodynamics of insulin aspart.
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- 2001
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- journal article
Pharmacokinetic-Pharmacodynamic Modelling of the antipyretic effect of two oral formulations of ibuprofen.
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- 2000
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- journal article
The Efficiency Concept in Pharmacodynamics.
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- Clinical Pharmacokinetics, 1999, v. 36, n. 5, p. 375
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Olanzapine. Pharmacokinetic and pharmacodynamic profile.
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- 1999
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- journal article
Clinical Pharmacokinetics and Pharmacodynamics of Artemether-Lumefantrine.
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- Clinical Pharmacokinetics, 1999, v. 37, n. 2, p. 105, doi. 10.2165/00003088-199937020-00002
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Pharmacodynamics and pharmacokinetics of thiopental.
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- 1998
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- journal article
Pharmacokinetics and pharmacodynamics of hydroxyurea.
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- 1998
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- journal article
Clinical pharmacokinetics and pharmacodynamics of torasemide.
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- 1998
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- journal article
Pharmacokinetics and pharmacodynamics of dopamine and norepinephrine in critically ill head-injured patients.
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- 2004
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- journal article
Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration.
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- 2020
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- journal article
Pharmacokinetics and pharmacodynamics of oral mecamylamine - development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation.
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- 2017
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- journal article
Pharmacokinetics, pharmacodynamics and safety of CEP-26401, a high-affinity histamine-3 receptor antagonist, following single and multiple dosing in healthy subjects.
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- 2016
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- journal article
Effects of nitazoxanide on pharmacokinetics and pharmacodynamics of a single dose of warfarin.
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- American Journal of Health-System Pharmacy, 2009, v. 66, n. 9, p. 838, doi. 10.2146/ajhp080332
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- Article
Applying antimicrobial pharmacodynamics to resistant gram-negative pathogens.
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- American Journal of Health-System Pharmacy, 2006, v. 63, n. 14, p. 1346, doi. 10.2146/ajhp050403
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- Article
Pharmacokinetics and pharmacodynamics of a novel amoxicillin/sulbactam/prednisolone intramammary infusion in lactating cows after repeated administrations.
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- Veterinární Medicína, 2014, v. 59, n. 5, p. 221, doi. 10.17221/7515-vetmed
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Pharmacokinetic–pharmacodynamic relationship of rocuronium under stable nitrous oxide–fentanyl or nitrous oxide–sevoflurane anesthesia in children.
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- Pediatric Anesthesia, 2006, v. 16, n. 7, p. 761, doi. 10.1111/j.1460-9592.2005.01840.x
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- Article
PHARMACOKINETICS AND PHARMACODYNAMICS OF LINEZOLID IN BURN PATIENTS.
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- Annals of Burns & Fire Disasters, 2018, v. 31, n. 2, p. 118
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- Article
Pharmacokinetic Pharmacodynamic Modelling Contributions to Improve Paediatric Anaesthesia Practice.
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- Journal of Clinical Medicine, 2022, v. 11, n. 11, p. 3009, doi. 10.3390/jcm11113009
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- Article