Background: Hair transplant surgery using follicular unit extraction technique (FUE) is a common surgical procedure for the treatment of prominent hair loss. This study aimed to determine the role of Platelet Rich Plasma (PRP) in the procedure of Follicular Unit Extraction (FUE). Patients and methods: A prospective comparative study was carried out in Plastic & Reconstructive Surgery Department of Zagazig University Hospitals during the period from January 2019 to January 2020. It included 16 patients with androgenic alopecia, patients included in the study was divided into two groups according to receiving RPR or not, Group (1); eight Patients treated with FUE with PRP. Group (2); eight Patients treated with FUE without PRP. The median age and degree of medical comorbidities were comparable in the two groups. Hair density indices were compared using Trichoscope. Results: All eight patients treated with PRP showed a good hair regrowth, with prefect outcome. Of the eight patients treated without PRP, five showed a good hair regrowth, with good outcome. Conclusion: This study demonstrated that PRP treatment during the hair transplant plays a significant role in hair re-growth, and it remarkably improves density and quality of hair growth.