Works matching DE "DRUG repositioning"

Results: 1680

Non‐Medical Applications of Inorganic Medicines. A Switch Based on Mechanistic Knowledge.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 60, p. 1, doi. 10.1002/chem.202402647

By:

Cirri, Damiano;
Di Leo, Riccardo;
Chiaverini, Lorenzo;
Tolbatov, Iogann;
Marrone, Alessandro;
Messori, Luigi;
Pratesi, Alessandro;
La Mendola, Diego;
Marzo, Tiziano

Publication type:

Article

TeM-DTBA: time-efficient drug target binding affinity prediction using multiple modalities with Lasso feature selection.

Published in:

Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 12, p. 573, doi. 10.1007/s10822-023-00533-1

By:

Liyaqat, Tanya;
Ahmad, Tanvir;
Saxena, Chandni

Publication type:

Article

Exploring DrugCentral: from molecular structures to clinical effects.

Published in:

Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 12, p. 681, doi. 10.1007/s10822-023-00529-x

By:

Halip, Liliana;
Avram, Sorin;
Curpan, Ramona;
Borota, Ana;
Bora, Alina;
Bologa, Cristian;
Oprea, Tudor I.

Publication type:

Article

Best practices for repurposing studies.

Published in:

Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 12, p. 1189, doi. 10.1007/s10822-021-00430-5

By:

Lewis, Richard A.

Publication type:

Article

How to make the best of NLRP3 inhibitors in patients with COVID-19?

Published in:

2023

By:

Kow, Chia Siang;
Ramachandram, Dinesh Sangarran;
Hasan, Syed Shahzad

Publication type:

Letter to the Editor

Drug repositioning in the COVID-19 pandemic: fundamentals, synthetic routes, and overview of clinical studies.

Published in:

European Journal of Clinical Pharmacology, 2023, v. 79, n. 6, p. 723, doi. 10.1007/s00228-023-03486-4

By:

Vaz, Elisa Souza;
Vassiliades, Sandra Valeria;
Giarolla, Jeanine;
Polli, Michelle Carneiro;
Parise-Filho, Roberto

Publication type:

Article

Editorial.

Published in:

European Health & Pharma Law Review, 2023, v. 7, n. 3, p. 95, doi. 10.21552/ehpl/2023/3/3

By:

Wested, Jakob

Publication type:

Article

Should Europe Adopt a Policy Like the US FDA's Project Renewal?

Published in:

European Health & Pharma Law Review, 2023, v. 7, n. 3, p. 126, doi. 10.21552/ehpl/2023/3/6

By:

Hamidzadeh, Ashleigh;
Liddicoat, Johnathon;
Liddell, Kathleen

Publication type:

Article

Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment.

Published in:

NPJ Aging, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41514-024-00138-4

By:

Lelarge, V.;
Capelle, R.;
Oger, F.;
Mathieu, T.;
Le Calvé, B.

Publication type:

Article

Contribution of Visceral Systems to the Development of Substance Use Disorders: Translational Aspects of Interaction between Central and Peripheral Mechanisms.

Published in:

Biochemistry (00062979), 2024, v. 89, n. 11, p. 1868, doi. 10.1134/S0006297924110026

By:

Peregud, Danil I.;
Gulyaeva, Natalia V.

Publication type:

Article

Pulmonary hypertension and the potential of 'drug' repurposing: A case for African medicinal plants.

Published in:

African Journal of Thoracic & Critcal Care Medicine, 2024, v. 30, n. 2, p. 59, doi. 10.7196/AJTCCM.2024.v30i2.1352

By:

Jacobs, S.;
Payne, C.;
Shaboodien, S.;
Kgatla, T.;
Pretorius, A.;
Jumaar, C.;
Maarman, G.;
Sanni, O.

Publication type:

Article

Computational drug repurposing based on electronic health records: a scoping review.

Published in:

NPJ Digital Medicine, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s41746-022-00617-6

By:

Zong, Nansu;
Wen, Andrew;
Moon, Sungrim;
Fu, Sunyang;
Wang, Liwei;
Zhao, Yiqing;
Yu, Yue;
Huang, Ming;
Wang, Yanshan;
Zheng, Gang;
Mielke, Michelle M.;
Cerhan, James R.;
Liu, Hongfang

Publication type:

Article

Computational drug repurposing in the age of COVID-19: mixing antiviral cocktails in silico.

Published in:

2022

By:

Diao, James A.;
Raza, Marium M.;
Venkatesh, Kaushik P.;
Kvedar, Joseph C.

Publication type:

Editorial

RNA-TARGETED DRUG REPURPOSING PIPELINE FOR AEROSPACE MEDICINE.

Published in:

Aerospace Medicine & Human Performance, 2024, v. 95, n. 8, p. 532

By:

Cerqueira, Bianca;
Reese, Justin;
Galeano, Diego;
Beheshti, Afshin;
Cappelletti, Luca;
Cates, Kim;
Caufield, Harry;
Smith, Timothy;
Chapapas, Holly;
Robinson, Meghan;
Sherman, Paul

Publication type:

Article

Current status of structure-based drug repurposing against COVID-19 by targeting SARS-CoV-2 proteins.

Published in:

Biophysics & Physicobiology, 2021, v. 18, n. 1, p. 226, doi. 10.2142/biophysico.bppb-v18.025

By:

Atsushi Hijikata;
Clara Shionyu;
Setsu Nakae;
Masafumi Shionyu;
Motonori Ota;
Shigehiko Kanaya;
Tsuyoshi Shirai

Publication type:

Article

A Regulatory Roadmap for Repurposing: Comparing Pathways for Making Repurposed Drugs Available In The EU, UK, And US.

Published in:

Journal of Law, Medicine & Ethics, 2024, v. 52, n. 4, p. 940, doi. 10.1017/jme.2024.171

By:

Scholte, Mirre;
Bendicksen, Liam;
Grimm, Sabine E.;
Abu-Zahra, Teebah;
Pauly, Bianca;
Joore, Manuela;
Kesselheim, Aaron S.

Publication type:

Article

Pharmaceutical Innovation in Latin America and the Caribbean.

Published in:

Journal of Law, Medicine & Ethics, 2023, v. 51, p. 148, doi. 10.1017/jme.2023.120

By:

Rama, Martín;
Vargas, Verónica;
Darrow, Jonathan

Publication type:

Article

Drug repurposing as add-on treatment strategy for mania and bipolar depression: systematic synthesis and qualitative appraisal of the existing meta-analytic evidence.

Published in:

2024

By:

Cavaleri, D.;
Bartoli, F.;
Crocamo, C.;
Carrà, G.

Publication type:

Abstract

Evaluation of Amlodipine and Imipramine Efficacy to Treat Galleria mellonella Infection by Biofilm-Producing and Antimicrobial-Resistant Staphylococcus aureus.

Published in:

Antibiotics (2079-6382), 2025, v. 14, n. 2, p. 183, doi. 10.3390/antibiotics14020183

By:

Andrade, Mariana;
Neves, Joana;
Bento, Maria;
Marques, Joana;
Seabra, Sofia G.;
Silveira, Henrique;
Rodrigues, Liliana;
Armada, Ana;
Viveiros, Miguel;
Couto, Isabel;
Costa, Sofia Santos

Publication type:

Article

Antimicrobial and Antibiofilm Activity of Auranofin and Its Two Derivatives Bearing Naproxen and Acetylcysteine as Ligands Against Staphylococci †.

Published in:

Antibiotics (2079-6382), 2025, v. 14, n. 2, p. 118, doi. 10.3390/antibiotics14020118

By:

Ferretti, Caterina;
Chiaverini, Lorenzo;
Poma, Noemi;
Dalli, Andrea;
Di Leo, Riccardo;
Rindi, Laura;
Marrone, Alessandro;
Tolbatov, Iogann;
La Mendola, Diego;
Tavanti, Arianna;
Marzo, Tiziano;
Di Luca, Mariagrazia

Publication type:

Article

Selective Serotonin Reuptake Inhibitors: Antimicrobial Activity Against ESKAPEE Bacteria and Mechanisms of Action.

Published in:

Antibiotics (2079-6382), 2025, v. 14, n. 1, p. 51, doi. 10.3390/antibiotics14010051

By:

Endo, Thiago Hideo;
Santos, Mariana Homem de Mello;
Scandorieiro, Sara;
Gonçalves, Bruna Carolina;
Vespero, Eliana Carolina;
Perugini, Márcia Regina Eches;
Pavanelli, Wander Rogério;
Nakazato, Gerson;
Kobayashi, Renata Katsuko Takayama

Publication type:

Article

Development of a Stringent Ex Vivo-Burned Porcine Skin Wound Model to Screen Topical Antimicrobial Agents.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 12, p. 1159, doi. 10.3390/antibiotics13121159

By:

Chen, Ping;
Sebastian, Eliza A.;
Karna, S. L. Rajasekhar;
Leung, Kai P.

Publication type:

Article

Innovative Strategies in Drug Repurposing to Tackle Intracellular Bacterial Pathogens.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 9, p. 834, doi. 10.3390/antibiotics13090834

By:

Lorente-Torres, Blanca;
Llano-Verdeja, Jesús;
Castañera, Pablo;
Ferrero, Helena Á.;
Fernández-Martínez, Sergio;
Javadimarand, Farzaneh;
Mateos, Luis M.;
Letek, Michal;
Mourenza, Álvaro

Publication type:

Article

The Many Lives of Auranofin: How an Old Anti-Rheumatic Agent May Become a Promising Antimicrobial Drug.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 7, p. 652, doi. 10.3390/antibiotics13070652

By:

Coscione, Francesca;
Zineddu, Stefano;
Vitali, Valentina;
Fondi, Marco;
Messori, Luigi;
Perrin, Elena

Publication type:

Article

Impact of Growth Conditions on High-Throughput Identification of Repurposing Drugs for Pseudomonas aeruginosa Cystic Fibrosis Lung Infections.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 7, p. 642, doi. 10.3390/antibiotics13070642

By:

Di Bonaventura, Giovanni;
Lupetti, Veronica;
Pompilio, Arianna

Publication type:

Article

Repositioning of HMG-CoA Reductase Inhibitors as Adjuvants in the Modulation of Efflux Pump-Mediated Bacterial and Tumor Resistance.

Published in:

Antibiotics (2079-6382), 2023, v. 12, n. 9, p. 1468, doi. 10.3390/antibiotics12091468

By:

Schelz, Zsuzsanna;
Muddather, Hiba F.;
Zupkó, István

Publication type:

Article

Utilization of Existing Human Kinase Inhibitors as Scaffolds in the Development of New Antimicrobials.

Published in:

Antibiotics (2079-6382), 2023, v. 12, n. 9, p. 1418, doi. 10.3390/antibiotics12091418

By:

Konaklieva, Monika I.;
Plotkin, Balbina J.

Publication type:

Article

Repurposing of Nitroxoline as an Alternative Primary Amoebic Meningoencephalitis Treatment.

Published in:

Antibiotics (2079-6382), 2023, v. 12, n. 8, p. 1280, doi. 10.3390/antibiotics12081280

By:

Chao-Pellicer, Javier;
Arberas-Jiménez, Iñigo;
Fuchs, Frieder;
Sifaoui, Ines;
Piñero, José E.;
Lorenzo-Morales, Jacob;
Scheid, Patrick

Publication type:

Article

Disulfiram: Mechanisms, Applications, and Challenges.

Published in:

Antibiotics (2079-6382), 2023, v. 12, n. 3, p. 524, doi. 10.3390/antibiotics12030524

By:

Lanz, Jenna;
Biniaz-Harris, Nicholas;
Kuvaldina, Mara;
Jain, Samta;
Lewis, Kim;
Fallon, Brian A.

Publication type:

Article

An Overview of Repurposed Drugs for Potential COVID-19 Treatment.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 12, p. 1678, doi. 10.3390/antibiotics11121678

By:

Govender, Kamini;
Chuturgoon, Anil

Publication type:

Article

Non-Antibiotic Drug Repositioning as an Alternative Antimicrobial Approach.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 6, p. 816, doi. 10.3390/antibiotics11060816

By:

Barbarossa, Alexia;
Rosato, Antonio;
Corbo, Filomena;
Clodoveo, Maria Lisa;
Fracchiolla, Giuseppe;
Carrieri, Antonio;
Carocci, Alessia

Publication type:

Article

Antiamoebic Properties of Laboratory and Clinically Used Drugs against Naegleria fowleri and Balamuthia mandrillaris.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 6, p. 749, doi. 10.3390/antibiotics11060749

By:

Siddiqui, Ruqaiyyah;
Mungroo, Mohammad Ridwane;
Anuar, Tengku Shahrul;
Alharbi, Ahmad M.;
Alfahemi, Hasan;
Elmoselhi, Adel B.;
Khan, Naveed Ahmed

Publication type:

Article

Niclosamide as a Repurposing Drug against Corynebacterium striatum Multidrug-Resistant Infections.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 5, p. 651, doi. 10.3390/antibiotics11050651

By:

Folliero, Veronica;
Dell'Annunziata, Federica;
Roscetto, Emanuela;
Cammarota, Marcella;
De Filippis, Anna;
Schiraldi, Chiara;
Catania, Maria Rosaria;
Casolaro, Vincenzo;
Perrella, Alessandro;
Galdiero, Massimiliano;
Franci, Gianluigi

Publication type:

Article

A Review: Antimicrobial Therapy for Human Pythiosis.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 4, p. N.PAG, doi. 10.3390/antibiotics11040450

By:

Medhasi, Sadeep;
Chindamporn, Ariya;
Worasilchai, Navaporn

Publication type:

Article

In Vitro Screening of a 1280 FDA-Approved Drugs Library against Multidrug-Resistant and Extensively Drug-Resistant Bacteria.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 3, p. 291, doi. 10.3390/antibiotics11030291

By:

Peyclit, Lucie;
Baron, Sophie Alexandra;
Hadjadj, Linda;
Rolain, Jean-Marc

Publication type:

Article

Drug Repurposing Targeting Pseudomonas aeruginosa MvfR Using Docking, Virtual Screening, Molecular Dynamics, and Free-Energy Calculations.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 2, p. 185, doi. 10.3390/antibiotics11020185

By:

Vieira, Tatiana F.;
Magalhães, Rita P.;
Simões, Manuel;
Sousa, Sérgio F.

Publication type:

Article

Repurposing Eltrombopag for Multidrug Resistant Staphylococcus aureus Infections.

Published in:

Antibiotics (2079-6382), 2021, v. 10, n. 11, p. 1372, doi. 10.3390/antibiotics10111372

By:

Lee, Hyunjung;
Lee, Jaehoan;
Hwang, Juchan;
Park, Sinyoung;
Kim, Namyoul;
Kim, Kideok;
Lee, Honggun;
Shum, David;
Jang, Soojin

Publication type:

Article

Computational Drug Repurposing for Antituberculosis Therapy: Discovery of Multi-Strain Inhibitors.

Published in:

Antibiotics (2079-6382), 2021, v. 10, n. 8, p. 1005, doi. 10.3390/antibiotics10081005

By:

Kleandrova, Valeria V.;
Scotti, Marcus T.;
Speck-Planche, Alejandro

Publication type:

Article

Antituberculosis Targeted Drug Delivery as a Potential Future Treatment Approach.

Published in:

Antibiotics (2079-6382), 2021, v. 10, n. 8, p. 908, doi. 10.3390/antibiotics10080908

By:

Mazlan, Mohd Khairul Nizam;
Mohd Tazizi, Mohammad Hafizie Dianel;
Ahmad, Rosliza;
Noh, Muhammad Amirul Asyraf;
Bakhtiar, Athirah;
Wahab, Habibah A.;
Mohd Gazzali, Amirah

Publication type:

Article

A Comprehensive Molecular and Clinical Investigation of Approved Anti-HCV Drugs Repurposing against SARS-CoV-2 Infection: A Glaring Gap between Benchside and Bedside Medicine.

Published in:

Vaccines, 2023, v. 11, n. 3, p. 515, doi. 10.3390/vaccines11030515

By:

Bansode, Sneha;
Singh, Pawan Kumar;
Tellis, Meenakshi;
Chugh, Anita;
Deshmukh, Narendra;
Gupta, Mahesh;
Verma, Savita;
Giri, Ashok;
Kulkarni, Mahesh;
Joshi, Rakesh;
Chaudhary, Dhruva

Publication type:

Article

Meta-Data Analysis to Explore the Hub of the Hub-Genes That Influence SARS-CoV-2 Infections Highlighting Their Pathogenetic Processes and Drugs Repurposing.

Published in:

Vaccines, 2022, v. 10, n. 8, p. 1248, doi. 10.3390/vaccines10081248

By:

Mosharaf, Md. Parvez;
Kibria, Md. Kaderi;
Hossen, Md. Bayazid;
Islam, Md. Ariful;
Reza, Md. Selim;
Mahumud, Rashidul Alam;
Alam, Khorshed;
Gow, Jeff;
Mollah, Md. Nurul Haque

Publication type:

Article

Multi-Targeted Approaches and Drug Repurposing Reveal Possible SARS-CoV-2 Inhibitors.

Published in:

Vaccines, 2022, v. 10, n. 1, p. 24, doi. 10.3390/vaccines10010024

By:

Alanazi, Khalid Mashay;
Farah, Mohammad Abul;
Hor, Yan-Yan

Publication type:

Article

Coronavirus Disease (COVID-19) Control between Drug Repurposing and Vaccination: A Comprehensive Overview.

Published in:

Vaccines, 2021, v. 9, n. 11, p. 1317, doi. 10.3390/vaccines9111317

By:

Al-Karmalawy, Ahmed A.;
Soltane, Raya;
Abo Elmaaty, Ayman;
Tantawy, Mohamed A.;
Antar, Samar A.;
Yahya, Galal;
Chrouda, Amani;
Pashameah, Rami Adel;
Mustafa, Muhamad;
Abu Mraheil, Mobarak;
Mostafa, Ahmed

Publication type:

Article

Drug repositioning approach to target viral and host cells in terms of COVID-19 treatment: A review of in vivo experiments and clinical studies.

Published in:

Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2022, v. 39, n. 4, p. 1255, doi. 10.52142/omujecm.39.4.56

By:

SHAHALİ, Ali;
AKBARI, Vajihe;
SOLTANI, Rasool;
BADRI, Shirin Sadat;
ARDESHIR, Rashid Alijani

Publication type:

Article

Navigating the Gene Co-Expression Network and Drug Repurposing Opportunities for Brain Disorders Associated with Neurocognitive Impairment.

Published in:

Brain Sciences (2076-3425), 2023, v. 13, n. 11, p. 1564, doi. 10.3390/brainsci13111564

By:

Manuel, Mathew Timothy Artuz;
Tayo, Lemmuel L.

Publication type:

Article

LINCS Dataset-Based Repositioning of Dutasteride as an Anti-Neuroinflammation Agent.

Published in:

Brain Sciences (2076-3425), 2021, v. 11, n. 11, p. 1411, doi. 10.3390/brainsci11111411

By:

Luo, Dan;
Han, Lu;
Gao, Shengqiao;
Xiao, Zhiyong;
Zhou, Qingru;
Cheng, Xiaorui;
Zhang, Yongxiang;
Zhou, Wenxia

Publication type:

Article

Identifying Hub Genes and Metabolic Pathways in Collagen VI-Related Dystrophies: A Roadmap to Therapeutic Intervention.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 11, p. 1376, doi. 10.3390/biom14111376

By:

Ceyhan, Atakan Burak;
Kaynar, Ali;
Altay, Ozlem;
Zhang, Cheng;
Temel, Sehime Gulsun;
Turkez, Hasan;
Mardinoglu, Adil

Publication type:

Article

Selective Inhibition of Deamidated Triosephosphate Isomerase by Disulfiram, Curcumin, and Sodium Dichloroacetate: Synergistic Therapeutic Strategies for T-Cell Acute Lymphoblastic Leukemia in Jurkat Cells.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 10, p. 1295, doi. 10.3390/biom14101295

By:

Flores-López, Luis A.;
De la Mora-De la Mora, Ignacio;
Malagón-Reyes, Claudia M.;
García-Torres, Itzhel;
Martínez-Pérez, Yoalli;
López-Herrera, Gabriela;
Hernández-Alcántara, Gloria;
León-Avila, Gloria;
López-Velázquez, Gabriel;
Olaya-Vargas, Alberto;
Gómez-Manzo, Saúl;
Enríquez-Flores, Sergio

Publication type:

Article

Repurposing Nitazoxanide for Potential Treatment of Rare Disease Lymphangioleiomyomatosis.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 10, p. 1236, doi. 10.3390/biom14101236

By:

Bähr, Stella;
Rue, Ryan W.;
Smith, Carly J.;
Evans, Jillian F.;
Köster, Hubert;
Krymskaya, Vera P.;
Pleimes, Dirk

Publication type:

Article

Functional Genomics and Insights into the Pathogenesis and Treatment of Psoriasis.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 5, p. 548, doi. 10.3390/biom14050548

By:

Shellard, Elan May;
Rane, Shraddha S.;
Eyre, Stephen;
Warren, Richard B.

Publication type:

Article