Works matching DE "MENDELIAN randomization"

Results: 1207

Shared genetic architecture between leukocyte telomere length and Alzheimer's disease.

Published in:

Alzheimer's Research & Therapy, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13195-025-01757-z

By:

Cao, Zhi;
Tan, Qilong;
Yang, Hongxi;
Xu, Chenjie

Publication type:

Article

Evaluating the causal effects of life-course adiposity on jaw anomalies.

Published in:

Progress in Orthodontics (2196-1042), 2025, v. 26, n. 1, p. 1, doi. 10.1186/s40510-025-00565-3

By:

Chen, Xin;
Cheng, Zheng;
Wang, Qianyi;
Jiang, Yubin;
Cheng, Qing;
Jiang, Qianglin

Publication type:

Article

The causal relationship between celiac disease and psoriasis: evidence from Mendelian randomization and meta-analysis.

Published in:

Archives of Dermatological Research, 2025, v. 317, n. 1, p. 1, doi. 10.1007/s00403-025-04253-4

By:

Wang, Ruixuan;
Fodei, Suad Ali Hassan;
Wang, Xinquan;
Chen, Wangqing;
Zhu, Wu

Publication type:

Article

Exploring causal associations between plasma metabolites and attention-deficit/hyperactivity disorder.

Published in:

BMC Psychiatry, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12888-025-06951-9

By:

Shi, Shangyun;
Baranova, Ancha;
Cao, Hongbao;
Zhang, Fuquan

Publication type:

Article

Association between Apolipoprotein B and diabetic nephropathy: insights from the National Health and Nutrition Examination Survey 2007–2016 and Mendelian randomization analysis.

Published in:

Nutrition & Diabetes, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41387-025-00370-1

By:

Wang, Hui;
Wu, Sensen;
Pan, Dikang;
Ning, Yachan;
Fu, Yanhong;
Feng, Chunjing;
Guo, Jianming;
Liu, Zichuan;
Gu, Yongquan

Publication type:

Article

The contribution of oral infectious diseases in lacunar stroke based on meta-analysis and Mendelian randomization study.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99742-x

By:

Zheng, Qifan;
Xu, Tong;
Luo, Shiyin;
Zhao, Jiahui;
Ying, Yue;
Liu, Nan;
Jiang, Aijia;
Pan, Yaping;
Zhang, Dongmei

Publication type:

Article

The causal effects of systemic antioxidant capacity on male infertility: A two-sample mendelian randomization analysis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-02243-0

By:

Zhang, Xiaolong;
Zhu, Zhirong;
Shen, Chaodong;
Tang, Guiliang

Publication type:

Article

MR.RGM: an R package for fitting Bayesian multivariate bidirectional Mendelian randomization networks Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 4, p. 1, doi. 10.1093/bioinformatics/btaf130

By:

Sarkar, Bitan;
Ni, Yang

Publication type:

Article

Genetic relationship between rheumatoid arthritis and cardiovascular diseases.

Published in:

Wiener Klinische Wochenschrift, 2025, v. 137, n. 9, p. 272, doi. 10.1007/s00508-024-02392-8

By:

Ausserwinkler, Mathias;
Gensluckner, Sophie;
Voelkerer, Andreas;
Thiel, Jens;
Neumann, Hans-Jörg;
Flamm, Maria;
Datz, Christian;
Aigner, Elmar;
Wernly, Bernhard

Publication type:

Article

A causal relationship between hypothyroidism and rheumatoid arthritis, but not hyperthyroidism: evidence from the mendelian randomization study.

Published in:

Wiener Klinische Wochenschrift, 2025, v. 137, n. 9, p. 279, doi. 10.1007/s00508-024-02386-6

By:

Yang, Mingyi;
Su, Yani;
Xu, Ke;
Wen, Pengfei;
Guo, Jianbin;
Yang, Zhi;
Liu, Lin;
Xu, Peng

Publication type:

Article

Distinct pathway-based effects of blood pressure and body mass index on cardiovascular traits: comparison of novel Mendelian randomization approaches.

Published in:

Genome Medicine, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13073-025-01472-2

By:

Leyden, Genevieve M.;
Sobczyk, Maria K.;
Richardson, Tom G.;
Gaunt, Tom R.

Publication type:

Article

Editorial: The immunological events of macrophages in the course of sepsis.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1610868

By:

Wu, Shiyun;
Li, Xu

Publication type:

Article

Blood biochemical landscape and new insights into clinical decision-making for polycystic ovary syndrome in Chinese women: a prospective cohort study.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1534733

By:

Li, Yutong;
Lin, Xiufeng;
Zou, Ke;
Du, Jing;
Li, Qingni;
Zhong, Linkun;
Jiang, Shan

Publication type:

Article

Associations of Genetically Predicted NPR3 and NPR2 Perturbation and Preeclampsia Risk: A Two‐Sample Mendelian Randomization Analysis.

Published in:

International Journal of Hypertension, 2025, v. 2025, p. 1, doi. 10.1155/ijhy/9972031

By:

Harpe, Roxane de La;
Rogne, Tormod;
Nyberg, Michael;
Cronjé, Héléne T.;
Burgess, Stephen;
Karhunen, Ville;
Gill, Dipender;
Pivetta, Emanuele

Publication type:

Article

Associations Between Lipid Traits and Breast Cancer Risk: A Mendelian Randomization Study in African Women.

Published in:

Cancer Medicine, 2025, v. 14, n. 9, p. 1, doi. 10.1002/cam4.70928

By:

Ansah, Emmanuel Owusu;
Kyei, Foster;
Opoku, Caleb Frimpong;
Danquah, Andrews;
Fosu, Kwadwo;
Agyenim, Emmanuel Boateng;
Agyirifo, Daniel Sakyi

Publication type:

Article

Assessment of causality association between serum adiponectin levels and the risk of Alzheimer's disease and Parkinson's disease: a Mendelian randomization study.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1395798

By:

Lin, Jiali;
Lei, Langhuan;
Liang, Qiuyu;
Huang, Xiaozhi;
Ding, Yanping;
Pan, Liuxian;
Yang, Jianrong;
Li, Wei

Publication type:

Article

Integration of metabolomics and genomics implicates a causality between 1398 blood metabolites and gout.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 5, p. 2053, doi. 10.1007/s10067-025-07402-2

By:

Fan, Mingyuan;
Yun, Zhangjun;
Yuan, Jiushu;
Lu, Dingyi;
Xie, Hongyan;
Yuan, Haipo;
Gao, Hong

Publication type:

Article

Dissecting the genetic determinants and biological associations between body mass index and female reproductive disorders based on genome-wide association study.

Published in:

Reproductive Biology & Endocrinology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12958-025-01406-y

By:

Shao, Huijing;
Xu, Chang;
Wang, Haoran;
Lu, Nan;
Gu, Hang;
Zhang, Caihong;
Li, Lirong;
Sun, Qianqian;
Guan, Rui;
Xuan, Beibei

Publication type:

Article

Exploring glucagon-like peptide-1 receptor agonists as potential disease-modifying agent in psychiatric and neurodevelopmental conditions: evidence from a drug target Mendelian randomization.

Published in:

BMC Psychiatry, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12888-025-06914-0

By:

Zhang, Lingfeng;
Chen, Xiang;
Xu, Yantao;
Liu, Jiachen;
Liu, Zhongchun

Publication type:

Article

CD28<sup>+</sup> CD45RA<sup>−</sup> CD8br AC mediated the effects of Interleukin- 6 on Alzheimer's disease: A Mendelian Randomization Study.

Published in:

BMC Neurology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12883-025-04194-5

By:

Xu, Rui;
Gao, YongJun

Publication type:

Article

Predicting dementia in people with Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-00983-4

By:

Aborageh, Mohamed;
Hähnel, Tom;
Martins Conde, Patricia;
Klucken, Jochen;
Fröhlich, Holger

Publication type:

Article

Causal Relationship Between Psychosocial Factors and Neck Pain: A Two-Sample Mendelian Randomization Study.

Published in:

Journal of Pain Research, 2025, v. 18, p. 2191, doi. 10.2147/JPR.S508287

By:

Liang, Haibo;
Wu, Qihang;
Yang, Shu;
Zhang, Shuhao;
Miao, Jiansen;
Jin, Haiming;
Wang, Xiangyang

Publication type:

Article

Association Between Educational Attainment and Chronic Pain: A Mediation Mendelian Randomization Study.

Published in:

Journal of Pain Research, 2025, v. 18, p. 1793, doi. 10.2147/JPR.S515921

By:

Wang, Hanqi;
Liu, Mingjuan;
Li, Hongbo;
Xu, Shijie

Publication type:

Article

Lack of a Causal Association between DNA Methylation GrimAge Acceleration and Brain Tumor Incidence: A Two-Sample Mendelian Randomization Study.

Published in:

Journal of Multidisciplinary Healthcare, 2025, v. 18, p. 1913, doi. 10.2147/JMDH.S503539

By:

Yang, Xinlei;
Wei, Guojun;
Fan, Yu;
Gao, Han;
Bao, Shengxin;
Sun, Xiaobo;
Sun, Jiming;
Du, Yiran

Publication type:

Article

A Systematic Review of Mendelian Randomization in Spontaneous Miscarriage.

Published in:

Journal of Multidisciplinary Healthcare, 2025, v. 18, p. 2237, doi. 10.2147/JMDH.S515367

By:

Xiang, Shiqing;
Jiang, Yi;
Mu, Fangxiang;
Wu, Hong;
Zhang, Nian

Publication type:

Article

Combined Transcriptomic and Mendelian Randomisation Explores the Diagnostic Value of Ubiquitination-Related Genes in Sepsis.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 4709, doi. 10.2147/JIR.S489077

By:

Bai, Xue;
Liu, RuXing;
Tang, Yujiao;
Yang, LiTing;
Niu, Zesu;
Hu, Yi;
Zhang, Ling;
Chen, MengFei

Publication type:

Article

Causal effects of depression on prostatitis: a two‐step Mendelian randomisation study with immune cell mediation.

Published in:

Psychogeriatrics, 2025, v. 25, n. 3, p. 1, doi. 10.1111/psyg.70023

By:

Liu, Feifan;
Han, Lijun;
Wang, Jianyu;
Song, Yufeng;
Wu, Fei;
Wu, Haihu;
Lyu, Jiaju;
Ning, Hao

Publication type:

Article

Causal Associations Between Pre-Pregnancy Diabetes Mellitus and Pre-Eclampsia Risk: Insights from a Mendelian Randomization Study.

Published in:

Healthcare (2227-9032), 2025, v. 13, n. 9, p. 1085, doi. 10.3390/healthcare13091085

By:

Ying, Xiang;
Wu, Quanfeng;
Li, Xiaohan;
Bi, Yan;
Gao, Li;
Yu, Shushu;
Xu, Xiaona;
Li, Xiaotian;
Wang, Yanlin;
Hua, Renyi

Publication type:

Article

Lipidomics Reveals Common Mechanisms in Polycystic Ovarian Syndrome, Recurrent Spontaneous Abortion, and Infertility: A Genetic-Based Analysis.

Published in:

International Journal of Women's Health, 2025, v. 17, p. 1055, doi. 10.2147/IJWH.S514221

By:

Tao, Ailin;
Wu, Tianqiang;
Han, Xinyu;
Niu, Dingren;
Feng, Xiaoling

Publication type:

Article

Association Between Dietary Taste Preferences and Primary Ovarian Insufficiency: A Mendelian Randomization Study.

Published in:

International Journal of Women's Health, 2025, v. 17, p. 1039, doi. 10.2147/IJWH.S505332

By:

Xu, Shuying;
Zhou, You;
Wang, Lina;
Zhang, Yang

Publication type:

Article

Bidirectional Two-Sample Mendelian Randomization Study Reveals Causal Associations Between Aging and Endometriosis.

Published in:

International Journal of Women's Health, 2025, v. 17, p. 1027, doi. 10.2147/IJWH.S504181

By:

Chen, Limei;
Yan, Han;
Nie, Jichan

Publication type:

Article

Exploring the Causal Role of miR-941 in Chronic Rhinosinusitis: Insights from Transcriptomics and Genomics.

Published in:

International Journal of General Medicine, 2025, v. 18, p. 1983, doi. 10.2147/IJGM.S511534

By:

Shu, Fu;
Wang, Yaping;
Zhang, Feng;
Li, Linglong;
Mao, Dehong

Publication type:

Article

No Associations Between Genetically Predicted Chronotype, Insomnia, Daytime Sleepiness, or Physical Activity and Acne Vulgaris: A Two-Sample Mendelian Randomization Study.

Published in:

Clinical, Cosmetic & Investigational Dermatology, 2025, v. 18, p. 827, doi. 10.2147/CCID.S510739

By:

Tian, Chaoqun

Publication type:

Article

Mendelian Randomization Combined with Single-Cell Transcriptome Analysis Reveals the Role of the Key Gene PCLAF in the Pathogenesis of Atopic Dermatitis.

Published in:

Clinical, Cosmetic & Investigational Dermatology, 2025, v. 18, p. 867, doi. 10.2147/CCID.S506139

By:

Tao, Rui;
Chen, Xuejie;
Wang, Yingying;
Li, Sicheng;
Zhou, Shengzhi;
Aghayants, Sis;
Yan, Lingling;
Zhang, Qi;
Zhu, Zhanyong

Publication type:

Article

Causal Impact of Immune Phenotypes on Herpes Zoster and Postherpetic Neuralgia: Insights from Mendelian Randomization Analysis.

Published in:

Clinical, Cosmetic & Investigational Dermatology, 2025, v. 18, p. 919, doi. 10.2147/CCID.S502861

By:

Yan, Zhangren;
Shen, Dandan;
Qiu, Xiaoqian;
Ai, Bohua;
Xiong, Chenxi

Publication type:

Article

Causal relationship between plasma lipidome and rosacea: a Mendelian randomization analysis.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1427656

By:

Wang, Xiaoxue;
Zhu, Zexin

Publication type:

Article

The Causal Effect of Basal Metabolic Rate on Type 2 Diabetes: A Two‐Sample Mendelian Randomization Study.

Published in:

Journal of Diabetes Research, 2025, p. 1, doi. 10.1155/jdr/6523642

By:

Huang, Yu;
Wen, Jianxuan;
Liao, Xiaofeng;
Chen, Guiling;
Zeng, Xiang;
Chen, Yu;
Chiefari, Eusebio

Publication type:

Article

Integrating plasma circulating protein-centered multi-omics to identify potential therapeutic targets for Parkinsonian cognitive disorders.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06541-z

By:

Tuersong, Tayier;
Yong, Yu Xuan;
Chen, Yan;
Li, Pei Shan;
Shataer, Samire;
Shataer, Munire;
Ma, Liang Ying;
Yang, Xin Ling

Publication type:

Article

Circulating mediators linking cardiometabolic diseases to HFpEF: a mediation Mendelian randomization analysis.

Published in:

Cardiovascular Diabetology, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12933-025-02738-0

By:

Lin, Mingzhi;
Guo, Jiuqi;
Tao, Hongqian;
Gu, Zhilin;
Tang, Wenyi;
Zhou, Fuliang;
Jiang, Yanling;
Zhang, Ruyi;
Jia, Dalin;
Sun, Yingxian;
Jia, Pengyu

Publication type:

Article

肠道菌群与食物过敏的因果关联: 一项孟德尔随机化分析.

Published in:

Chinese Journal of Contemporary Pediatrics, 2025, v. 27, n. 4, p. 444, doi. 10.7499/j.issn.1008-8830.2409021

By:

胡丽鑫;
范国振;
马慧;
李蕾;
王芳;
曲政海;
管仁政

Publication type:

Article

Causal effect of gut microbiota metabolic pathways on CSAG1 expression in chondrosarcoma: a mendelian randomization analysis.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14281-y

By:

Liu, Xiaoyun;
Yang, Sen;
Liu, Liyun

Publication type:

Article

Micronutrients and skin cancer risk: a Mendelian randomization study.

Published in:

World Journal of Surgical Oncology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12957-025-03814-1

By:

Chen, Wangcheng;
Pang, Lili;
Wei, Xiuzhen;
Lan, Yuemei;
Su, Xiayi;
Dong, Yaling;
Zhu, Zhibo;
Bai, Jie;
Zhou, Jiayan;
Cui, Heteng;
Zhang, Baihong

Publication type:

Article

Post-genome-wide association study dissects genetic vulnerability and risk gene expression of Sjögren's disease for cardiovascular disease.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06568-2

By:

Yi, Xinglin;
Liu, Erxiong;
Wang, Yong

Publication type:

Article

Metabolic pathways mediating insulin resistance and gestational diabetes mellitus discovered by high-dimensional systematic Mendelian randomization.

Published in:

Cardiovascular Diabetology, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12933-025-02746-0

By:

Chen, Wei;
Luo, Mingjuan;
Guo, Jingyi;
Wang, Suna;
Yan, Dandan;
Feng, Xiaohui;
Huang, Yunting;
Zeng, Tao;
Shen, Li;
Zhang, Rong;
Yan, Jing;
Hu, Cheng;
Zhang, Weituo;
Yu, Xiangtian

Publication type:

Article

DECIPHERING THE ROLE OF PYROPTOSIS-RELATED GENES AND NATURAL KILLER T CELLS IN SEPSIS PATHOGENESIS: A COMPREHENSIVE BIOINFORMATICS AND MENDELIAN RANDOMIZATION ANALYSIS.

Published in:

Journal of Physiology & Pharmacology, 2025, v. 76, n. 2, p. 209, doi. 10.26402/jpp.2025.2.10

By:

ZHOU, L.;
DONG, W.;
LIU, Y.

Publication type:

Article

Exploring the diagnostic potential of IL1R1 in depression and its association with lipid metabolism.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1519287

By:

Gao, Yao;
Song, Xiao-Na;
Zhang, Nan;
Liu, Huang-Hui;
Hu, Jian-Zhen;
Du, Xin-Zhe;
Song, Guo-Hua;
Liu, Sha

Publication type:

Article

Revisiting the causal impact of lipid traits on metabolic dysfunction‐associated fatty liver disease: Insights from a multidimensional plasma lipid profile.

Published in:

Journal of Diabetes Investigation, 2025, v. 16, n. 5, p. 917, doi. 10.1111/jdi.14413

By:

Xie, Fang;
Zheng, Wenkai;
Chen, Jing;
Yao, Chuanxia;
Li, Cong;
Tang, Li;
Li, Ping;
Tan, Shanzhong

Publication type:

Article

Associations between psoriasis and risk of 33 cancers: a Mendelian randomization study.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14243-4

By:

Liu, Mengsi;
Sun, Zhen;
Tan, Peixin;
Xie, Dehuan;
Liu, Yantan;
Feng, Wenqing;
Ren, Chen;
Du, Shasha

Publication type:

Article

基于生物信息学联合孟德尔随机化分析探讨类风湿关节炎相关通路在肺鳞癌中的作用与机制.

Published in:

Science Technology & Engineering, 2025, v. 25, n. 11, p. 4467, doi. 10.12404/j.issn.1671-1815.2402571

By:

代家兴;
唐东昕;
李沅音;
张少望;
杨兵

Publication type:

Article

Identifying the genetic link between type 1 diabetes and autoimmune liver diseases.

Published in:

Clinical & Experimental Hepatology, 2025, v. 11, n. 1, p. 52, doi. 10.5114/ceh.2025.149078

By:

Yu, Guo;
Dong, Tao;
Gu, Haoyuan;
Liang, Depeng;
Song, Liming;
Shi, Jijing;
Duan, Xibin;
Ma, Chao

Publication type:

Article