Works matching AU Nicolau, David P.
Results: 271
Pharmacokinetics of ABT-773, a new semi-synthetic ketolide in neutropenic lung-infected mice: a population approach.
- Published in:
- Journal of Pharmacy & Pharmacology, 2002, v. 54, n. 1, p. 71, doi. 10.1211/0022357021771940
- By:
- Publication type:
- Article
Pharmacokinetics of Ticlopidine in the Rabbit.
- Published in:
- Journal of Pharmacy & Pharmacology, 1999, v. 51, n. 4, p. 393, doi. 10.1211/0022357991772583
- By:
- Publication type:
- Article
Pharmacokinetic/Pharmacodynamic Target Attainment Based on Measured versus Predicted Unbound Ceftriaxone Concentrations in Critically Ill Patients with Pneumonia: An Observational Cohort Study.
- Published in:
- Antibiotics (2079-6382), 2021, v. 10, n. 5, p. 557, doi. 10.3390/antibiotics10050557
- By:
- Publication type:
- Article
Pharmacokinetics and Pharmacodynamics of Cefepime in Adults with Hematological Malignancies and Febrile Neutropenia after Chemotherapy.
- Published in:
- Antibiotics (2079-6382), 2021, v. 10, n. 5, p. 504, doi. 10.3390/antibiotics10050504
- By:
- Publication type:
- Article
Pharmacodynamics of Ceftibuten: An Assessment of an Oral Cephalosporin against Enterobacterales in a Neutropenic Murine Thigh Model.
- Published in:
- Antibiotics (2079-6382), 2021, v. 10, n. 2, p. 201, doi. 10.3390/antibiotics10020201
- By:
- Publication type:
- Article
Development and Application of a Pragmatic Algorithm to Guide Definitive Carbapenemase Testing to Identify Carbapenemase-Producing Pseudomonas aeruginosa.
- Published in:
- Antibiotics (2079-6382), 2020, v. 9, n. 11, p. 738, doi. 10.3390/antibiotics9110738
- By:
- Publication type:
- Article
Augmented Renal Clearance and How to Augment Antibiotic Dosing.
- Published in:
- Antibiotics (2079-6382), 2020, v. 9, n. 7, p. 393, doi. 10.3390/antibiotics9070393
- By:
- Publication type:
- Article
Optimising Dosing Strategies of Antibacterials Utilising Pharmacodynamic Principles: Impact on the Development of Resistance.
- Published in:
- Drugs, 2006, v. 66, n. 1, p. 1, doi. 10.2165/00003495-200666010-00001
- By:
- Publication type:
- Article
Antibacterial activity of ceftolozane/tazobactam alone and in combination with other antimicrobial agents against MDR Pseudomonas aeruginosa.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Can we improve clinical outcomes in patients with pneumonia treated with antibiotics in the intensive care unit?
- Published in:
- Expert Review of Respiratory Medicine, 2016, v. 10, n. 8, p. 907, doi. 10.1080/17476348.2016.1190277
- By:
- Publication type:
- Article
Transitions of care in the management of acute bacterial skin and skin structure infections: a paradigm shift.
- Published in:
- Expert Review of Clinical Pharmacology, 2016, v. 9, n. 8, p. 1039, doi. 10.1080/17512433.2016.1195683
- By:
- Publication type:
- Article
Optimizing Antibiotic Dosing Strategies for the Treatment of Gram-negative Infections in the Era of Resistance.
- Published in:
- Expert Review of Clinical Pharmacology, 2016, v. 9, n. 3, p. 459, doi. 10.1586/17512433.2016.1133286
- By:
- Publication type:
- Article
In vitro potency of amikacin against carbapenem-resistant Pseudomonas aeruginosa: A target for nebulization strategy?
- Published in:
- Brazilian Journal of Infectious Diseases, 2022, v. 26, n. 2, p. 1, doi. 10.1016/j.bjid.2022.102355
- By:
- Publication type:
- Article
Assessing the pharmacodynamic profile of intravenous antibiotics against prevalent Gram-negative organisms collected in Colombia.
- Published in:
- Brazilian Journal of Infectious Diseases, 2011, v. 15, n. 5, p. 413, doi. 10.1016/S1413-8670(11)70221-5
- By:
- Publication type:
- Article
Development and confirmation of humanized plasma and epithelial lining fluid exposures of meropenem, cefiderocol and tobramycin in a standardized neutropenic murine pneumonia model.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2025, v. 80, n. 2, p. 478, doi. 10.1093/jac/dkae432
- By:
- Publication type:
- Article
Establishment of a diverse pheno-genotypic challenge set of Klebsiella pneumoniae and Pseudomonas aeruginosa suitable for use in the murine pneumonia model.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2025, v. 80, n. 1, p. 154, doi. 10.1093/jac/dkae388
- By:
- Publication type:
- Article
Differential frequency of persister cells in clinically derived isolates of Pseudomonas aeruginosa after exposure to cefiderocol and ceftolozane/tazobactam.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 12, p. 3236, doi. 10.1093/jac/dkae346
- By:
- Publication type:
- Article
Quantitative performance of humanized serum and epithelial lining fluid exposures of tigecycline and levofloxacin against a challenge set of Klebsiella pneumoniae and Pseudomonas aeruginosa in a standardized neutropenic murine pneumonia model.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 12, p. 3142, doi. 10.1093/jac/dkae333
- By:
- Publication type:
- Article
Defining optimal sulbactam regimens for treatment of Acinetobacter baumannii pneumonia and impact of bla<sub>OXA-23</sub> on efficacy.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 9, p. 2306, doi. 10.1093/jac/dkae229
- By:
- Publication type:
- Article
Ampicillin-sulbactam against Acinetobacter baumannii infections: pharmacokinetic/pharmacodynamic appraisal of current susceptibility breakpoints and dosing recommendations.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 9, p. 2227, doi. 10.1093/jac/dkae218
- By:
- Publication type:
- Article
Assessing the impact of meropenem exposure on ceftolozane/tazobactam-resistance development in Pseudomonas aeruginosa using in vitro serial passage.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 5, p. 1176, doi. 10.1093/jac/dkae089
- By:
- Publication type:
- Article
Imipenem/relebactam pharmacokinetics in critically ill patients supported on extracorporeal membrane oxygenation.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 5, p. 1118, doi. 10.1093/jac/dkae079
- By:
- Publication type:
- Article
Assessing the in vivo impact of novel β-lactamase inhibitors on the efficacy of their partner β-lactams against serine carbapenemase-producing Pseudomonas aeruginosa using human-simulated exposures.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 3, p. 546, doi. 10.1093/jac/dkad412
- By:
- Publication type:
- Article
In vitro activity of cefiderocol against a global collection of carbapenem-resistant Pseudomonas aeruginosa with a high level of carbapenemase diversity.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 2, p. 412, doi. 10.1093/jac/dkad396
- By:
- Publication type:
- Article
In vitro synergy of the combination of sulbactam-durlobactam and cefepime at clinically relevant concentrations against A. baumannii, P. aeruginosa and Enterobacterales.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 12, p. 2801, doi. 10.1093/jac/dkad244
- By:
- Publication type:
- Article
Activity of novel β-lactam/β-lactamase inhibitor combinations against serine carbapenemase-producing carbapenem-resistant Pseudomonas aeruginosa.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 12, p. 2795, doi. 10.1093/jac/dkad225
- By:
- Publication type:
- Article
Imipenem/funobactam (formerly XNW4107) in vivo pharmacodynamics against serine carbapenemase-producing Gram-negative bacteria: a novel modelling approach for time-dependent killing.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 9, p. 2343, doi. 10.1093/jac/dkad242
- By:
- Publication type:
- Article
Cefepime in vivo activity against carbapenem-resistant Enterobacterales that test as cefepime susceptible or susceptible-dose dependent in vitro: implications for clinical microbiology laboratory and clinicians.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 9, p. 2242, doi. 10.1093/jac/dkad229
- By:
- Publication type:
- Article
Assessing the in vivo efficacy of rational antibiotics and combinations against difficult-to-treat Pseudomonas aeruginosa producing GES β-lactamases.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 8, p. 1843, doi. 10.1093/jac/dkad098
- By:
- Publication type:
- Article
In vivo efficacy & resistance prevention of cefiderocol in combination with ceftazidime/avibactam, ampicillin/sulbactam or meropenem using human-simulated regimens versus Acinetobacter baumannii.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 4, p. 983, doi. 10.1093/jac/dkad032
- By:
- Publication type:
- Article
Bronchopulmonary disposition of IV cefepime/taniborbactam (2–0.5 g) administered over 2 h in healthy adult subjects.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 3, p. 703, doi. 10.1093/jac/dkac447
- By:
- Publication type:
- Article
In vivo pharmacokinetic/pharmacodynamic evaluation of cefepime/taniborbactam combination against cefepime-non-susceptible Enterobacterales and Pseudomonas aeruginosa in a murine pneumonia model.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 3, p. 692, doi. 10.1093/jac/dkac446
- By:
- Publication type:
- Article
Phenotypes, genotypes and breakpoints: an assessment of β-lactam/β-lactamase inhibitor combinations against OXA-48.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 3, p. 636, doi. 10.1093/jac/dkac425
- By:
- Publication type:
- Article
Pharmacokinetics and soft-tissue distribution of tebipenem pivoxil hydrobromide using microdialysis: a study in healthy subjects and patients with diabetic foot infections.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 1, p. 296, doi. 10.1093/jac/dkac399
- By:
- Publication type:
- Article
Phenotypic and genotypic profile of ceftolozane/tazobactam-non-susceptible, carbapenem-resistant Pseudomonas aeruginosa.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 1, p. 252, doi. 10.1093/jac/dkac385
- By:
- Publication type:
- Article
Relative bioavailability of crushed tebipenem administered through a nasogastric tube with and without enteral feeding.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 1, p. 205, doi. 10.1093/jac/dkac375
- By:
- Publication type:
- Article
In vivo pharmacokinetics and pharmacodynamics of ceftibuten/ledaborbactam, a novel oral β-lactam/β-lactamase inhibitor combination.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 1, p. 93, doi. 10.1093/jac/dkac359
- By:
- Publication type:
- Article
Trimethoprim/sulfamethoxazole pharmacodynamics against Stenotrophomonas maltophilia in the in vitro chemostat model.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2022, v. 77, n. 11, p. 3187, doi. 10.1093/jac/dkac304
- By:
- Publication type:
- Article
Imipenem/cilastatin/relebactam pharmacokinetics in critically ill patients with augmented renal clearance.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2022, v. 77, n. 11, p. 2992, doi. 10.1093/jac/dkac261
- By:
- Publication type:
- Article
Plasma and cerebrospinal fluid concentrations of cefiderocol during successful treatment of carbapenem-resistant Acinetobacter baumannii meningitis.
- Published in:
- 2022
- By:
- Publication type:
- journal article
In vivo translational assessment of the GES genotype on the killing profile of ceftazidime, ceftazidime/avibactam and meropenem against Pseudomonas aeruginosa.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Phenotypes, genotypes and breakpoints: an assessment of β-lactam/ β-lactamase inhibitor combinations against OXA-48.
- Published in:
- 2022
- By:
- Publication type:
- journal article
In vivo exposure-response relationship of meropenem against metallo-β-lactamase-harbouring Pseudomonas aeruginosa: an assessment using MICs from conventional and zinc-limited broth.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2022, v. 77, n. 7, p. 1938, doi. 10.1093/jac/dkac141
- By:
- Publication type:
- Article
In vivo efficacy of WCK 6777 (ertapenem/zidebactam) against carbapenemase-producing Klebsiella pneumoniae in the neutropenic murine pneumonia model.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Omadacycline pharmacokinetics and soft-tissue penetration in diabetic patients with wound infections and healthy volunteers using in vivo microdialysis.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Minocycline pharmacodynamics against Stenotrophomonas maltophilia in the neutropenic murine infection model: implications for susceptibility breakpoints.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Clinical exposure-response relationship of cefepime/taniborbactam against Gram-negative organisms in the murine complicated urinary tract infection model.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Levofloxacin pharmacodynamics against Stenotrophomonas maltophilia in a neutropenic murine thigh infection model: implications for susceptibility breakpoint revision.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Comment on: An update on cefepime and its future role in combination with novel β-lactamase inhibitors for MDR Enterobacterales and Pseudomonas aeruginosa.
- Published in:
- 2021
- By:
- Publication type:
- Letter
Erratum to: Intrapulmonary pharmacokinetic profile of cefiderocol in mechanically ventilated patients with pneumonia.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2021, v. 76, n. 11, p. 3069, doi. 10.1093/jac/dkab343
- By:
- Publication type:
- Article