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Results: 121

Rip1 enhances methylmercury toxicity through production of reactive oxygen species (ROS) in budding yeast.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 715, doi. 10.2131/jts.34.715
By:
- Jin-Yong Lee;
- Gi-Wook Hwang;
- Naganuma, Akira
Publication type:
Article
A protein assey for heme oxygenase-1 (HO-1) induced by chemicals in HepG2 cells.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 709, doi. 10.2131/jts.34.709
By:
- Miyamoto, Yohei;
- Ohshida, Keiyu;
- Sasago, Kaori
Publication type:
Article
Dysfunctional nascent polypeotide-associated complex (NAC) activity in ribosomes enhances adriamycin toxicity in budding yeast.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 703, doi. 10.2131/jts.34.703
By:
- Takahashi, Tsutomu;
- Hirose, Ken-ichiro;
- Mizutani, Emi;
- Naganuma, Akira
Publication type:
Article
Carbonated soft drinks and carbonyl stress burden.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 699, doi. 10.2131/jts.34.699
By:
- Nakayama, Keisuke;
- Nakayama, Masaaki;
- Terawaki, Hiroyuki;
- Murata, Yaeko;
- Sato, Toshinobu;
- Kohno, Masahiro;
- Ito, Sadayoshi
Publication type:
Article
In vitro and in vivo evaluation of mutagenicity of fucoxanthin (FX) and its metabolite fucoxanthinol (FXOH).
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 693, doi. 10.2131/jts.34.693
By:
- Beppu, Fumiaki;
- Niwano, Yoshimi;
- Sato, Emiko;
- Kohno, Masahiro;
- Tsukui, Takayuki;
- Hosokawa, Masashi;
- Miyashita, Kazuo
Publication type:
Article
Effect ofperfluorooctane sulfonate (PFOS) on influenza A virus-induced mortality in female B6C3F1 mice.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 687, doi. 10.2131/jts.34.687
By:
- Guruge, Keerthi S.;
- Hikono, Hirokazu;
- Shimada, Nobuaki;
- Murakami, Kenji;
- Hasegawa, Jun;
- Yeung, Leo W. Y.;
- Yamanaka, Noriko;
- Yamashita, Nobuyoshi
Publication type:
Article
Sexing of postimplantation rat embryos in stored two-dimensional electrophoresis (2-DE) samples by polymerase chain reaction (PCR) of an Sry sequence.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 681, doi. 10.2131/jts.34.681
By:
- Miyajima, Atsuko;
- Sunouchi, Momoko;
- Mitsunaga, Katsuyoshi;
- Yamakoshi, Yoko;
- Nakazawa, Ken;
- Usami, Makoto
Publication type:
Article
Paraquat (PQ)-induced pulmonary fibrosis increases exercise metabolic cost, reducing aerobic perfomance in rats.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 671, doi. 10.2131/jts.34.671
By:
- Lacerda, Ana Cristina Rodrigues;
- Rodrigues-Machado, Maria da Glória;
- Mendes, Polyana Leite;
- Novaes, Rômulo Dias;
- Carvalho, Giovanna Marcella Cavalcante;
- Zin, Walter Araujo;
- Gripp, Fernando;
- Coimbra, Cândido Celso
Publication type:
Article
Toxic responses to deltamethrin (DM) low doses on gonads, sex hormones and lipoperoxidation in male rats following subcutaneous treatments.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 663, doi. 10.2131/jts.34.663
By:
- Issam, Chargui;
- Samir, Haouem;
- Zohra, Haouas;
- Monia, Zaouali;
- Hassen, Ben Cheikh
Publication type:
Article
Comprehensive analysis of hepatic gene and protein expression profiles on phenobarbital- or clofibrate-induced hepatic hypertrophy in dogs.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 647, doi. 10.2131/jts.34.647
By:
- Makino, Toshihiko;
- Kinoshita, Junzo;
- Arakawa, Shingo;
- Ito, Kazumi;
- Ando, Yosuke;
- Yamoto, Takashi;
- Teranishi, Munehiro;
- Sanbuissho, Atsushi;
- Nakayama, Hiroyuki
Publication type:
Article
Inhibition property of green tea extract in relation to reserpine-induced ribosomal strips of rough endoplasmic reticulum (rER) of the rat kidney proximal tubule cells.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 637, doi. 10.2131/jts.34.637
By:
- Abdel-Majeed, Safer;
- Mohammad, Afzal;
- Shaima, Al-Bloushi;
- Mohammad, Rafique;
- Mousa, Shaker A.
Publication type:
Article
Catechol estrogens mediated activation of Nrf2 through covalent modification of its quinone metabolite to Keap1.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 627, doi. 10.2131/jts.34.627
By:
- Sumi, Daigo;
- Numasawa, Yumiko;
- Endo, Akiko;
- Iwamoto, Noriko;
- Kumagai, Yoshito
Publication type:
Article
Inter-laboratory study of short time exposure (STE) test gor predicting eye irritation potential of chemicals and correspondence to globally harmonized system (GHS) classification.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 611, doi. 10.2131/jts.34.611
By:
- Takahashi, Yutaka;
- Hayashi, Takumi;
- Watanabe, Shinichi;
- Hayashi, Kazuhiko;
- Koike, Mirei;
- Aisawa, Noriko;
- Ebata, Shinya;
- Sakaguchi, Hitoshi;
- Nakamura, Tsuneaki;
- Kuwahara, Hirofumi;
- Nishiyama, Naohiro
Publication type:
Article
Phenobarbital (PB)-induced changes in blood coagulation-related parameters in pregnant rats, lactating rats and pups.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 603, doi. 10.2131/jts.34.603
By:
- Mochizuki, Masahiro;
- Shimizu, Satomi;
- Kidokoro, Yuri;
- Kamata, Takashi;
- Kitazawa, Takahiro;
- Kishi, Daisuke;
- Okazaki, Emi;
- Nishihata, Yoshito;
- Ohishi, Takumi
Publication type:
Article
Charateristics of troponins as myocardial damage biomarkers in cynomolgus monkeys.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 6, p. 589, doi. 10.2131/jts.34.589
By:
- Minomo, Hirofumi;
- Torikai, Yusuke;
- Furukawa, Tomohiro;
- Uchino, Hiroshi;
- Kadokura, Hidetomi;
- Nakama, Kazuhiro;
- Maeda, Hiroshi;
- Kamenosono, Takeshi;
- Sukamoto, Takayuki;
- Fukuzaki, Koichiro;
- Nagata, Ryoichi
Publication type:
Article
Letter to the Editor.
Published in:
2009
By:
- Tyl, Rochelle W.
Publication type:
Letter
Hepatotoxicity and subchronic toxicity tests of Morinda citrifolia (noni) fruit.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 581, doi. 10.2131/jts.34.581
By:
- West, Brett J.;
- Su, Chen X.;
- Jensen, C. Jarakae
Publication type:
Article
Tributyltin sensitivity of vacuolar-type Na+-transporting ATPase from Enterococcus hirae.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 575, doi. 10.2131/jts.34.575
By:
- Chardwiriyapreecha, Soracom;
- Inoue, Tomohiro;
- Sugimoto, Naoko;
- Sekito, Takayuki;
- Yamato, Ichiro;
- Murata, Takeshi;
- Homma, Michio;
- Kakinuma, Yoshimi
Publication type:
Article
Neurotoxicity of perfluorooctane sulfonate (PFOS) in rates and mice after single oral exposure.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 569, doi. 10.2131/jts.34.569
By:
- Sato, Itaru;
- Kawamoto, Kosuke;
- Nishikawa, Yasuo;
- Tsuda, Shuji;
- Yoshida, Midori;
- Yaegashi, Kaori;
- Saito, Norimitsu;
- Wei Liu;
- Yihe Jin
Publication type:
Article
Famotidine neither affects action potential parameters nor inhibits human ether-a-go-go-related gene (hERG) K+ current.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 563, doi. 10.2131/jts.34.563
By:
- Nakamura, Yuji;
- Takahara, Akira;
- Sugiyama, Atsushi
Publication type:
Article
Safety evaluation of highly purified fullerenes (HPFs): based on screening of eye and skin damage.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 555, doi. 10.2131/jts.34.555
By:
- Aoshima, Hisae;
- Saitoh, Yasukazu;
- Ito, Shinobu;
- Yamana, Shuichi;
- Miwa, Nobuhiko
Publication type:
Article
Multi-endpoint genotoxic assay using L5178Y (Tk+/- -3.7.2c) cells.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 547, doi. 10.2131/jts.34.547
By:
- Ogawa, Izumi;
- Furukawa, Satoshi;
- Abe, Masayoshi;
- Tanaka, Yoshinori;
- Hayashi, Seigo;
- Usuda, Koji
Publication type:
Article
Tributyltin induces Yca1p-dependent cell death of yeast Saccharomyces cerevisiae.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 541, doi. 10.2131/jts.34.541
By:
- Chahomchuen, Thippayarat;
- Akiyama, Koichi;
- Sekito, Takayuki;
- Sugimoto, Naoko;
- Okabe, Masaaki;
- Nishimoto, Sogo;
- Sugahara, Takuya;
- Kakinuma, Yoshimi
Publication type:
Article
Multiple organ toxicity, including hypochromic anemia, following repeated dose oral administration of phenobarbital (PB) in rats.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 527, doi. 10.2131/jts.34.527
By:
- Kojima, Sayuri;
- Sasaki, Junya;
- Tomita, Mariko;
- Saka, Machiko;
- Ishizuka, Katsumi;
- Kawakatsu, Hisao;
- Yoshida, Toshinori;
- Kosaka, Tadashi;
- Enomoto, Akiko;
- Nakashima, Nobuaki;
- Harada, Takanori
Publication type:
Article
Severe toxicity and cyclooxygenase (COX)-2 mRNA increase by lithium in the neonatal mouse kidney.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 519, doi. 10.2131/jts.34.519
By:
- Yoshioka, Wataru;
- Akagi, Toshiya;
- Nishimura, Noriko;
- Shimizu, Hana;
- Watanabe, Chiho;
- Tohyama, Chiharu
Publication type:
Article
Perfusion fluids used in neurosurgery affect cerebrospinal fluid and surrounding brain parenchyma in the rat ventriculocisternal perfusion model.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 511, doi. 10.2131/jts.34.511
By:
- Doi, Kazuhisa;
- Morioka, Yujiro;
- Nishimura, Masuhiro;
- Kawano, Takeshi;
- Harada, Daisuke;
- Naito, Shinsaku;
- Yamauchi, Aiko
Publication type:
Article
Single and repeated oral does toxicity study of fucoxanthin (FX), a marine carotenoid, in mice.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 501, doi. 10.2131/jts.34.501
By:
- Beppu, Fumiaki;
- Niwano, Yoshimi;
- Tsukui, Takayuki;
- Hosokawa, Masashi;
- Miyashita, Kazuo
Publication type:
Article
Good Laboratory Practice (GLP) status of Asian countries and its implementation in non-clinical safety studies in pharmaceutical drug development.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 493, doi. 10.2131/jts.34.493
By:
- Sasaki, Madoka;
- Hinotsu, Shiro;
- Kawakami, Koji
Publication type:
Article
Diesel exhaust (DE) aggravates pathology of delayed-type hypersensitivity (DTH) Induced by methyl-bovine serum albumin (mBSA) in mice.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 483, doi. 10.2131/jts.34.483
By:
- Sakai, Masanobu;
- Yamashita, Keichiro;
- Takemoto, Naoya;
- Ohshima, Yasuhiro;
- Tsukimoto, Mitsutoshi;
- Shinkai, Yusuke;
- Takeda, Ken;
- Oshio, Shigeru;
- Kojima, Shuji
Publication type:
Article
Low dose effects of dichlorodiphenyltrichloroethane (DDT) on gene transcription and DNA methylation in the hypothalamus of young male rats: implication of hormeses-like effects.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 469, doi. 10.2131/jts.34.469
By:
- Shutoh, Yasufumi;
- Takeda, Makio;
- Ohtsuka, Ryoichi;
- Haishima, Atsuko;
- Yamaguchi, Satoru;
- Fujie, Hideaki;
- Komatsu, Yutaka;
- Maita, Keizo;
- Harada, Takanori
Publication type:
Article
Heavy oil fractions induce negative influences on mouse immune system.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 459, doi. 10.2131/jts.34.459
By:
- Nishimoto, Sogo;
- Kanda, Kota;
- Yamawaki, Manami;
- Okabe, Masaaki;
- Akiyama, Koichi;
- Kakinuma, Yoshimi;
- Sugahara, Takuya
Publication type:
Article
Protective role of metallothionein in benzo[a]pyrene-induced DNA damage.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 5, p. 449, doi. 10.2131/jts.34.449
By:
- Takaishi, Masaki;
- Sawada, Masumi;
- Shimada, Akinori;
- Suzuki, Junko S.;
- Satoh, Masahiko;
- Nagase, Hisamitsu
Publication type:
Article
DNA microarray analysis of transcriptional responses of mouse spinal cords to physical exercise.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 445, doi. 10.2131/jts.34.445
By:
- Hashimoto, Kazunori;
- Honda, Akiko;
- Hayashi, Yuichi;
- Inuzuka, Takashi;
- Satoh, Masahiko;
- Hozumi, Isao
Publication type:
Article
Overexpression of Ycg1 or Ydr520c confers resistance to cadmium in Saccharomyces cerevisiae.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 441, doi. 10.2131/jts.34.441
By:
- Gi-Wook Hwang;
- Sasaki, Kanae;
- Takahashi, Tsutomu;
- Yamamoto, Reiko;
- Naganuma, Akira
Publication type:
Article
Suppression of fibroblast growth factor-2 expression: Possible mechanism underlying methylmercury-induced inhibition of the repair of wounded monolayers of cultured human brain microvascular endothelial cells.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 433, doi. 10.2131/jts.34.433
By:
- Hirooka, Takashi;
- Fujiwara, Yasuyuki;
- Inoue, Shoku;
- Shinkai, Yasuhiro;
- Yamamoto, Chika;
- Satoh, Masahiko;
- Yasutake, Akira;
- Eto, Komyo;
- Kaji, Toshiyuki
Publication type:
Article
Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 427, doi. 10.2131/jts.34.427
By:
- Yamaura, Katsunori;
- Oda, Manabu;
- Suwa, Eriko;
- Suzuki, Masahiko;
- Sato, Hiromi;
- Ueno, Koichi
Publication type:
Article
Internal exposure to 210Po and 40K from ingestion of cooked daily foodstuffs for adults in Japanese cities.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 417, doi. 10.2131/jts.34.417
By:
- Sugiyama, Hideo;
- Terada, Hiroshi;
- Isomura, Kimio;
- Iijima, Ikuyo;
- Kobayashi, Jun;
- Kitamura, Kiyoshi
Publication type:
Article
Overexpression of the novel F-box protein Ymr258c confers resistance to methylmercury in Saccharomyces cerevisiae.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 413, doi. 10.2131/jts.34.413
By:
- Gi-Wook Hwang;
- Wada, Naomi;
- Kuge, Shusuke;
- Naganuma, Akira
Publication type:
Article
Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 407, doi. 10.2131/jts.34.407
By:
- Young-Man Cho;
- Imai, Toshio;
- Hasumura, Mai;
- Watanabe, Naoko;
- Ushijima, Toshikazu;
- Hirose, Masao;
- Nishikawa, Akiyoshi
Publication type:
Article
Selenium increases expression of HSP70 and antioxidant enzymes to lessen oxidative damage in Fincoal-type fluorosis.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 399, doi. 10.2131/jts.34.399
By:
- Qun Chen;
- Zhilun Wang;
- Yongmin Xiong;
- Wanli Xue;
- Xibin Kao;
- Yan Gao;
- Muhammad, Nawaz;
- Daiqin Song
Publication type:
Article
Genotoxicity studies of ubidecarenone (coenzyme Q10) manufactured by bacteria fermentation.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 389, doi. 10.2131/jts.34.389
By:
- Yamaguchi, Noriko;
- Nakamura, Kaori;
- Oguma, Yoshihiro;
- Fujiwara, Sho;
- Takabe, Michihito;
- Sono, Akira;
- Kawasaki, Tsuneshirou;
- Otsubo, Kazumasa;
- Wakigawa, Koichi
Publication type:
Article
Effects of fenofibrate on plasma and hepatic transaminase activities and hepatic transaminase gene expression in rats.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 377, doi. 10.2131/jts.34.377
By:
- Kobayashi, Akio;
- Suzuki, Yusuke;
- Kuno, Hideyuki;
- Sugai, Shoichiro;
- Sakakibara, Hiroyuki;
- Shimoi, Kayoko
Publication type:
Article
Cytotoxicity of nanoparticles independent from oxidative stress.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 363
By:
- Fröhlich, Eleonore;
- Samberger, Claudia;
- Kueznik, Tatjana;
- Absenger, Markus;
- Roblegg, Eva;
- Zimmer, Andreas;
- Pieber, Thomas R.
Publication type:
Article
Changes in blood coagulation-related parameters in phenobarbital-treated rabbits.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 4, p. 357, doi. 10.2131/jts.34.357
By:
- Mochizuki, Masahiro;
- Abe, Hajime;
- Wakabayashi, Kei;
- Yoshinaga, Hiroyasu;
- Okazaki, Emi;
- Saito, Tsubasa;
- Fujita, Mariko;
- Edamoto, Hiroshi;
- Asano, Yuzo
Publication type:
Article
Views inspired from a recent paper: Recommendation on the nonparametric Dunnett test using collaborative work on the evaluation of ovarian toxicity.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 3, p. 355, doi. 10.2131/jts.34.355
Publication type:
Article
A comparative study on oxidative damage and distributions of perfluorooctane sulfonate (PFOS) in mice at different postnatal developmental stages.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 3, p. 245, doi. 10.2131/jts.34.245
By:
- Li Liu;
- Wei Liu;
- Hongyao Yu;
- Yihe Jin;
- Kazunori Oami;
- Sato, Itaru;
- Saito, Norimitsu;
- Tsuda, Shuji
Publication type:
Article
Comparative suppression of phthalate monoesters and phthalate diesters on calcium signalling coupled to nicotinic acetylcholine receptors.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 3, p. 255, doi. 10.2131/jts.34.255
By:
- Pei-Shan Liu;
- Fu-Wei Tseng;
- Jenn-Hwa Liu
Publication type:
Article
Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 3, p. 281, doi. 10.2131/jts.34.281
By:
- Hirode, Mitsuhiro;
- Omura, Ko;
- Kiyosawa, Naoki;
- Uehara, Takeki;
- Shimuzu, Toshinobu;
- Ono, Atsushi;
- Miyagishima, Toshikazu;
- Nagao, Taku;
- Ohno, Yasuo;
- Urushidani, Tetsuro
Publication type:
Article
Metabolism of tellurium, antimony and germanium simultaneously administered to rats.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 3, p. 295, doi. 10.2131/jts.34.295
By:
- Kobayashi, Akihiro;
- Ogra, Yasumitsu
Publication type:
Article
Toxicity studies of Asahi Kasei PI, purified phosphatidylinositol from soy lecithin.
Published in:
Journal of Toxicological Sciences, 2009, v. 34, n. 3, p. 265, doi. 10.2131/jts.34.265
By:
- Honda, Kumiko;
- Enoshima, Teruhiko;
- Oshikata, Takafumi;
- Kamiya, Koichi;
- Hamamura, Masao;
- Yamaguchi, Noriko;
- Nakamura, Kaori;
- Oguma, Yoshihiro;
- Fujiwara, Sho;
- Takabe, Michihito;
- Sono, Akira;
- Kawasaki, Tsuneshirou;
- Nasu, Masaaki;
- Otsubo, Kazumasa;
- Wakigawa, Koichi
Publication type:
Article