Nursing staff have been tried and convicted of murdering patients. This qualitative study described attributes of nurses who killed patients in healthcare institutions and characteristics of murder events. Data sources included news reports, books, and court records. Results revealed personality and behavioral indicators manifested by nurses who murdered or were accused of murdering patients, and details of murder events. Registered nurses were accused and convicted of murder most frequently; male nursing staff were disproportionately represented. Old and acutely ill patients were frequent victims and poisoning with medications, the usual murder method. Power/dominance ranked as the most frequent motive.