Buildings have their thermal and energetic behavior determined by their surrounding environment. However, most studies of building performance are carried out with climatic data from rural meteorological stations. Thus, the goal of this research was to evaluate variations in indoor air temperature and in relative consumption for cooling in a laboratory building, at the Federal University of Paraná (UFPR) Centro Politécnico campus, in Curitiba. The analysis was carried out based on two climatic data. The EcoDesigner STAR plug-in for the ArchiCAD construction information modeling (BIM) program was used for analysis. The energy consumption for cooling of the building was analyzed considering natural ventilation. The results showed that the use of a climatic file from a rural meteorological station would underestimate the energy consumption for refrigeration by up to 13.11% and the values of air temperature in up to 3.3%, when the building is naturally ventilated.