Salivary Flow Rate, pH, Buffering Capacity, Total Protein, Oxidative Stress and Antioxidant Capacity in Children with and without Dental Caries.

Pyati, Sudharani A.; R., Naveen Kumar; Kumar, Vinod; N. H., Praveen Kumar; Reddy, K. M. Parveen; Naveen Kumar, R; Praveen Kumar, N H; Parveen Reddy, K M

Objectives: To measure and compare the levels of salivary flow rate, pH, buffering capacity, total protein, malondialdehyde (MDA) and total antioxidant capacity (TAC) between caries active and caries free children and to study the correlation between the DMFS/dfs score and above salivary parameters in caries active children.Study Design: 50 caries active (DMFS/dfs ≥ 5) and 50 caries free (DMFS/dfs = 0) children aged between 6 to 12 years were included in the study. From all the children, unstimulated, mid-morning saliva samples were collected and salivary flow rate was calculated. Salivary pH, buffering capacity, total protein, MDA and TAC were measured.Results: The mean levels of salivary flow rate, pH, buffering capacity were significantly decreased (p 0.05) in salivary total protein, MDA and TAC as DMFS/dfs score increased in caries active children.Conclusions: Significant alteration in the levels of salivary flow rate, pH, total proteins, MDA and TAC and their correlation with DMFS/dfs score in caries active children suggest, the levels of these physico-chemical properties of saliva can act as strong indicators of caries status in children.

CHILDREN'S dental care; DENTAL caries in children; PEDIATRIC dentistry; SALIVA pH; SALIVA analysis; OXIDATIVE stress; PROTEIN metabolism; ANTIOXIDANTS; DENTAL caries; HYDROGEN-ion concentration; METABOLISM; SALIVA; MALONDIALDEHYDE; CASE-control method

Journal of Clinical Pediatric Dentistry, 2018, Vol 42, Issue 6, p445

1053-4628

Academic Journal

10.17796/1053-4625-42.6.7