Mukus Epidermis Clarias Batrachus Merencat Pertumbuhan Bakteria Gram Negatif.

SAHALAN, AHMAD ZORIN; SHARMILA, ENGKU; SULAIMAN, NAZAHIYAH

Recently, epidermal mucus of fish has been identified as a rich biological source of various bioactive substances, particularly antibacterial peptides. This study was conducted to identify the potential of epidermal mucosa of Clarias batrachus as a source of antibacterial material. Mucosal samples were collected from C. batrachus epidermis and extracted using an aqueous extraction method. Antibacterial activity of the crude epidermal mucus extract was determined by using spectrophotometric method. As a result there was antibacterial activity by the mucus extract against Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853). The results of this study supports the role of mucus as a part of body immune system with antibacterial peptide as a component of innate body immune system. Hence, these findings can be used as one of the first steps towards the development of new class antibiotics.

Malaysian Journal of Health Sciences / Jurnal Sains Kesihatan Malaysia, 2018, Vol 16, p83

1675-8161

Academic Journal

10.17576/JSKM-2018-12