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Title

The Hypothalamic-Pituitary-Adrenal Axis and Low-Dose Glucocorticoids in the Treatment of Septic Shock.

Authors

Williamson, David R.; Lapointe, Marc

Abstract

Explores the therapeutic benefits of glucocorticoids in patients with septic shock. Overview of the hypothalamic-pituitary-adrenal axis in critically ill patients; Mechanisms of action of glucocorticoids in septic shock; Results of clinical studies on replacement therapy with low-dose glucocorticoids.

Subjects

GLUCOCORTICOIDS; SEPTIC shock treatment; HYPOTHALAMIC-pituitary-adrenal axis; THERAPEUTICS; CLINICAL trials

Publication

Pharmacotherapy, 2003, Vol 23, Issue 4, p514

ISSN

0277-0008

Publication type

Academic Journal

DOI

10.1592/phco.23.4.514.32123

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