Title: Comparação entre o teste Oncotype DX e critérios prognósticos padronizados em câncer de mama receptor de estrogênio positivo em estágio inicial.
Authors: Freitas, Marcelo Roberto Pereira; Simon, Sergio Daniel
Abstract: Objective: To compare the prognosis estimated by standard prognostic criteria versus the prognosis estimated by the Oncotype DX. Methods: A retrospective study was performed on 22 patients with positive estrogen receptor, early-stage breast cancer who had an Oncotype DX recurrence score available. Results: Kappa value between Oncotype DX and standard prognostic criteria was: Adjuvant! (K = 0.091), Adjuvant! (Transbig) (K = 0.182) and National Comprehensive Cancer Network (K = 0.091). The Fisher's exact test did not show correlation between Oncotype and standard prognostic criteria. Conclusion: Standard prognostic criteria showed no correlation with Oncotype DX.
Subjects: BREAST cancer treatment; GENE expression; CANCER prognosis; ESTROGEN receptors; COMPARATIVE studies; RETROSPECTIVE studies; STATISTICAL correlation
Publication: Einstein (16794508), 2011, Vol 9, Issue 3, p354
ISSN: 1679-4508
Publication type: Academic Journal
DOI: 10.1590/s1679-45082011ao2039

Comparação entre o teste Oncotype DX e critérios prognósticos padronizados em câncer de mama receptor de estrogênio positivo em estágio inicial.

Freitas, Marcelo Roberto Pereira; Simon, Sergio Daniel