Severe esophagitis induced by antituberculosis drugs: a case report.

Mamani, Roxana Flores; Silva, Franciele Moreira; de Lima-Júnior, Marcos Vidal; de Oliveira Lima, Juliana Paitach; Vianna, Vitor Montez; Trindade de Azevedo, Rivelino; McBenedict, Billy; Martins, Ezequias Batista

Tuberculosis stands as one of humanity's oldest afflictions, intrinsically intertwined with social disparities. This formidable disease spares no age group and remains the prevailing cause of infection-induced mortality worldwide, particularly in developing nations. We present a case of a 56-year-old woman with diabetes who was diagnosed with Pulmonary Tuberculosis. After receiving antituberculosis drugs as part of her treatment, she experienced a range of systemic manifestations and suffered from severe ulcerative esophagitis. This adverse reaction led to uncontrollable gastrointestinal intolerance, tragically resulting in her untimely demise. The incident underscores the potential seriousness of adverse reactions that can arise from tuberculosis treatment medications.

ANTITUBERCULAR agents; TUBERCULOSIS; DEVELOPING countries; AGE groups; DRUGS

Revista do Instituto de Medicina Tropical de São Paulo, 2024, Vol 66, p1

0036-4665

Academic Journal

10.1590/S1678-9946202466002