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Title

Can molecular imaging techniques identify biomarkers for neuropsychiatric disorders?

Authors

Bressan, Rodrigo A.; Shih, Ming C.; Hoexter, Marcelo Q.; Lacerda, Acioly L. T.

Abstract

The article discusses the effectiveness of molecular imaging techniques, such as positron emission tomography (PET) and single photon emission computerized tomography (SPECT), in the identification of biomarkers for neuropsychiatric disorders (NPD). Accordingly, these techniques use radiolabeled tracers which allow direct investigation of neuroreceptors in vivo at any stage of the NPD. An example of such identification are the dopamine transporter (DAT) radiotracers that evaluate dopamine neuronal loss in Parkinson's disease (PD).

Subjects

POSITRON emission tomography; BIOMARKERS; NEUROPSYCHIATRY; RADIOACTIVE tracers; DOPAMINE; PARKINSON'S disease

Publication

Brazilian Journal of Psychiatry / Revista Brasileira de Psiquiatria, 2007, Vol 29, Issue 2, p102

ISSN

1516-4446

Publication type

Academic Journal

DOI

10.1590/S1516-44462007000200003

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