PATIENT SAFETY IN THE ADMINISTRATION OF ANTINEOPLASTIC CHEMOTHERAPY AND OF IMMUNOTHERAPICS FOR ONCOLOGICAL TREATMENT: SCOPING REVIEW.

Peres de Oliveira, Patrícia; Pereira Santos, Viviane Euzébia; dos Santos Bezerril, Manacés; Belmiro de Andrade, Fernanda; de Melo Paiva, Renilly; Araújo da Silveira, Edilene Aparecida

Objective: to identify and synthesize the scientific evidence on cancer patient safety in the administration of antineoplastic and immunotherapeutic chemotherapeutic agents. Method: a scoping review, according to the Joanna Briggs Institute and to the recommendations of the PRISMA-ScR international guide. The research was conducted in five electronic databases, the Cochrane Library and eight catalogs of theses and dissertations. The inclusion criteria were the following: studies related to patient safety in the administration of antineoplastic and immunotherapeutic chemotherapy by nurses in places where cancer care occurs, published entirely in Portuguese, Spanish and/or English, with no time limit. The extracted data were analyzed and synthesized in narrative form. Results: a total of 14,444 records were retrieved and 47 studies were kept for review. Most publications (44.7%) had a qualitative approach, while 40.4% were quantitative and 14.9%, mixed. When summarizing the findings, the following themes emerged: Safety standards in parenteral administration of antineoplastic chemotherapy; Good practices for patient safety using oral antineoplastic therapy; Administration and safe handling of immunotherapies; Prevention and management of errors related to the administration of antineoplastic and immunotherapeutic chemotherapeutic agents. Conclusion: patients safety with cancer in the administration of antineoplastic therapy occurs when there is implementation of evidence-based protocols, continuing education of nurses and implementation of safety standards and processes, as a strategy to prevent errors in drug administration.

MEDICATION error prevention; ANTINEOPLASTIC agents; CANCER chemotherapy; CANCER patient medical care; CINAHL database; IMMUNOTHERAPY; INFORMATION storage & retrieval systems; MEDICAL databases; MEDLINE; ONLINE information services; PATIENT safety; RESEARCH funding; SYSTEMATIC reviews; DESCRIPTIVE statistics

Texto & Contexto Enfermagem, 2019, Vol 28, p1

0104-0707

Academic Journal

10.1590/1980-265X-TCE-2018-0312