Works matching DE "DEOXYCYTIDINE"

Results: 546

Structural basis for cisplatin DNA damage tolerance by human polymerase ? during cancer chemotherapy.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 628, doi. 10.1038/nsmb.2295

By:

Ummat, Ajay;
Rechkoblit, Olga;
Jain, Rinku;
Roy Choudhury, Jayati;
Johnson, Robert E;
Silverstein, Timothy D;
Buku, Angeliki;
Lone, Samer;
Prakash, Louise;
Prakash, Satya;
Aggarwal, Aneel K

Publication type:

Article

How to 'PrEP' for HIV Prevention in Women.

Published in:

Journal of Women's Health (15409996), 2017, v. 26, n. 2, p. 195, doi. 10.1089/jwh.2016.6318

By:

Ntim, Gifty-Maria J.;
Kransdorf, Lisa N.

Publication type:

Article

Synthese eines DNA-Promotorsegments mit allen vier epigenetischen Nukleosiden: 5-Methyl-, 5-Hydroxymethyl-, 5-Formyl- und 5-Carboxy-2′-Desoxycytidin.

Published in:

Angewandte Chemie, 2014, v. 126, n. 1, p. 321, doi. 10.1002/ange.201308469

By:

Schröder, Arne S.;
Steinbacher, Jessica;
Steigenberger, Barbara;
Gnerlich, Felix A.;
Schiesser, Stefan;
Pfaffeneder, Toni;
Carell, Thomas

Publication type:

Article

Effects of 5-Aza-2′-deoxycytidine (decitabine) on gene expression.

Published in:

Drug Metabolism Reviews, 2018, v. 50, n. 2, p. 193, doi. 10.1080/03602532.2018.1437446

By:

Seelan, Ratnam S.;
Mukhopadhyay, Partha;
Pisano, M. Michele;
Greene, Robert M.

Publication type:

Article

Afatinib as First-line Treatment of Older Patients With EGFR Mutation-Positive Non-Small-Cell Lung Cancer: Subgroup Analyses of the LUX-Lung 3, LUX-Lung 6, and LUX-Lung 7 Trials.

Published in:

2018

By:

Wu, Yi-Long;
Sequist, Lecia V;
Tan, Eng-Huat;
Geater, Sarayut L;
Orlov, Sergey;
Zhang, Li;
Lee, Ki Hyeong;
Tsai, Chun-Ming;
Kato, Terufumi;
Barrios, Carlos H;
Schuler, Martin;
Hirsh, Vera;
Yamamoto, Nobuyuki;
O'Byrne, Kenneth;
Boyer, Michael;
Mok, Tony;
Peil, Barbara;
Märten, Angela;
Chih-Hsin Yang, James;
Paz-Ares, Luis

Publication type:

journal article

Efficacy and Safety of Necitumumab Continuation Therapy in the Phase III SQUIRE Study of Patients With Stage IV Squamous Non-Small-Cell Lung Cancer.

Published in:

2018

By:

Ciuleanu, Tudor;
Socinski, Mark A.;
Obasaju, Coleman;
Luft, Alexander V.;
Szczesna, Aleksandra;
Szafrański, Wojciech;
Ramlau, Rodryg;
Bálint, Beatrix;
Molinier, Olivier;
Depenbrock, Henrik;
Nanda, Shivani;
Paz-Ares, Luis;
Thatcher, Nick

Publication type:

journal article

Long-term Outcomes of Induction Carboplatin and Gemcitabine Followed by Concurrent Radiotherapy With Low-dose Paclitaxel and Gemcitabine for Stage III Non-small-cell Lung Cancer.

Published in:

2017

By:

Guilbault, Catherine;
Garant, Aurelie;
Faria, Sergio;
Owen, Scott;
Ofiara, Linda;
Duclos, Marie;
Hirsh, Vera;
Kopek, Neil

Publication type:

journal article

Phase II Trial of Dose-dense Pemetrexed, Gemcitabine, and Bevacizumab in Patients With Advanced, Non-Small-cell Lung Cancer.

Published in:

2017

By:

Schneider, Bryan J.;
Kalemkerian, Gregory P.;
Gadgeel, Shirish M.;
Valdivieso, Manuel;
Hackstock, Deborah M.;
Wei Chen;
Heilbrun, Lance K.;
Ruckdeschel, John C.;
Wozniak, Antoinette J.;
Chen, Wei

Publication type:

journal article

Correlation of DNA Repair Gene Polymorphisms With Clinical Outcome in Patients With Locally Advanced Non-Small-Cell Lung Cancer Receiving Induction Chemotherapy Followed by Surgery.

Published in:

2017

By:

Santarpia, Mariacarmela;
Ramirez, Jose Luis;
de Aguirre, Itziar;
Garrido, Pilar;
Pérez Cano, Maria;
Queralt, Cristina;
Gonzalez-Larriba, Jose Luis;
Insa, Amelia;
Provencio, Mariano;
Isla, Dolores;
Camps, Carlos;
Blanco, Remei;
Moran, Teresa;
Rosell, Rafael;
Spanish Lung Cancer Group

Publication type:

journal article

Biweekly Carboplatin Plus Gemcitabine as First-Line Treatment of Elderly Patients With Advanced Squamous Non-Small-cell Lung Cancer: A Multicenter Phase I-II Trial by the Hellenic Oncology Research Group.

Published in:

2016

By:

Karampeazis, Athanasios;
Vamvakas, Lambros;
Kentepozidis, Nikolaos;
Polyzos, Aris;
Chandrinos, Vassilis;
Rigas, Georgios;
Christofyllakis, Charalambos;
Kotsakis, Athanasios;
Hatzidaki, Dora;
Pallis, Athanasios G.;
Georgoulias, Vassilis

Publication type:

journal article

Differential sensitization of two human colon cancer cell lines to the antitumor effects of irinotecan combined with 5-aza-2'-deoxycytidine.

Published in:

Oncology Letters, 2018, v. 15, n. 4, p. 4641, doi. 10.3892/ol.2018.7883

By:

Hakata, Shuko;
Terashima, Jun;
Shimoyama, Yu;
Okada, Kouji;
Fujioka, Shiho;
Ito, Erika;
Habano, Wataru;
Ozawa, Shogo

Publication type:

Article

Role of 5-Aza-CdR in mitomycin-C chemosensitivity of T24 bladder cancer cells.

Published in:

Oncology Letters, 2017, v. 14, n. 5, p. 5652, doi. 10.3892/ol.2017.6853

By:

HUI-HUI ZHANG;
BO HUANG;
YOU-HAN CAO;
QING LI;
HAN-FENG XU

Publication type:

Article

Delineating the effect of demethylating agent 5-aza-2'-deoxycytidine on human Caco-2 colonic carcinoma cells.

Published in:

Oncology Letters, 2016, v. 12, n. 1, p. 139, doi. 10.3892/ol.2016.4551

By:

XIUMEI LI;
BINGZHAO QIN;
BO LIU

Publication type:

Article

Demethylation drug 5-Aza-2'-deoxycytidine-induced upregulation of miR-200c inhibits the migration, invasion and epithelial-mesenchymal transition of clear cell renal cell carcinoma in vitro.

Published in:

Oncology Letters, 2016, v. 11, n. 5, p. 3167, doi. 10.3892/ol.2016.4364

By:

JUAN JIANG;
BO YI;
SIQING DING;
JIAN SUN;
WEI CAO;
MENGZI LIU

Publication type:

Article

Abnormal methylation status of FBXW10 and SMPD3, and associations with clinical characteristics in clear cell renal cell carcinoma.

Published in:

Oncology Letters, 2015, v. 10, n. 5, p. 3073, doi. 10.3892/ol.2015.3707

By:

JINYOU WANG;
JIAN LI;
JUN GU;
JIAN YU;
SHICHENG GUO;
YAO ZHU;
DINGWEI YE

Publication type:

Article

Effect of combined 5-aza-2'deoxycytidine and cisplatin treatment on the P15 lung adenocarcinoma cell line.

Published in:

Oncology Letters, 2015, v. 9, n. 5, p. 2007, doi. 10.3892/ol.2015.2986

By:

KAISHAN LIU;
WENYAN HUANG;
WEISONG GAO;
WENFANG HE

Publication type:

Article

Role of PTCH1 gene methylation in gastric carcinogenesis.

Published in:

Oncology Letters, 2014, v. 8, n. 2, p. 679, doi. 10.3892/ol.2014.2178

By:

YUN ZUO;
YU SONG;
MIN ZHANG;
ZHEN XU;
XIAOLAN QIAN

Publication type:

Article

All-trans retinoic acid enhances the effect of 5-aza-2'-deoxycytidine on p16INK4a demethylation, and the two drugs synergistically activate retinoic acid receptor β gene expression in the human erythroleukemia K562 cell line.

Published in:

Oncology Letters, 2014, v. 8, n. 1, p. 117, doi. 10.3892/ol.2014.2133

By:

LILI XIANG;
WEIMIN DONG;
RONG WANG;
JIANG WEI;
GUOQIANG QIU;
JIANNONG CEN;
ZIXING CHEN;
XIAO ZHENG;
SHAOYAN HU;
XIAOBAO XIE;
XIANGSHAN CAO;
WEIYING GU

Publication type:

Article

Should Patients Be Required to Undergo Standard Chemotherapy Before Being Eligible for Novel Phase I Immunotherapy Clinical Trials?

Published in:

2017

By:

Wilfond, Benjamin S.;
Morales, Christian;
Taylor, Holly A.

Publication type:

Case Study

Loss of heterozygosity and methylation of multiple tumor suppressor genes on chromosome 3 in hepatocellular carcinoma.

Published in:

Journal of Gastroenterology, 2013, v. 48, n. 1, p. 132, doi. 10.1007/s00535-012-0621-0

By:

Zhang, Xiaoying;
Li, Hiu;
Liu, Zhiyan;
Zhou, Gengyin;
Zhang, Qinghui;
Zhang, Tingguo;
Zhang, Jianping;
Zhang, Cuijuan

Publication type:

Article

A Humanized Yeast Phenomic Model of Deoxycytidine Kinase to Predict Genetic Buffering of Nucleoside Analog Cytotoxicity.

Published in:

Genes, 2019, v. 10, n. 10, p. 770, doi. 10.3390/genes10100770

By:

Santos, Sean M.;
Icyuz, Mert;
Pound, Ilya;
William, Doreen;
Guo, Jingyu;
McKinney, Brett A.;
Niederweis, Michael;
Rodgers, John;
Hartman IV, John L.

Publication type:

Article

Downregulation and DNA methylation of ECRG4 in gastric cancer.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 4019, doi. 10.2147/OTT.S161200

By:

Deng, Peng;
Chang, Xiao-Jing;
Gao, Zi-Ming;
Xu, Xiao-Yang;
Sun, An-Qi;
Li, Kai;
Dai, Dong-Qiu

Publication type:

Article

A new tumor suppressor lncRNA RP11-190D6.2 inhibits the proliferation, migration, and invasion of epithelial ovarian cancer cells.

Published in:

OncoTargets & Therapy, 2017, v. 10, p. 1227, doi. 10.2147/OTT.S125185

By:

Wenxian Tong;
Liu Yang;
Qiang Yu;
Jie Yao;
Anbing He

Publication type:

Article

Low concentrations of 5-aza-2'-deoxycytidine induce breast cancer stem cell differentiation by triggering tumor suppressor gene expression.

Published in:

OncoTargets & Therapy, 2016, v. 9, p. 49, doi. 10.2147/OTT.S96291

By:

Nhan Lu-Chinh Phan;
Ngu Van Trinh;
Phuc Van Pham

Publication type:

Article

The nexus of vitamin homeostasis and DNA synthesis and modification in mammalian brain.

Published in:

Molecular Brain, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-6606-7-3

By:

Spector, Reynold;
Johanson, Conrad E.

Publication type:

Article

Investigating epigenetic effects of activation-induced deaminase in chronic lymphocytic leukemia.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208753

By:

Schubert, Maria;
Hackl, Hubert;
Gassner, Franz Josef;
Greil, Richard;
Geisberger, Roland

Publication type:

Article

Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0195048

By:

Ziegler, Samantha J.;
Liu, Chang;
Landau, Mark;
Buzovetsky, Olga;
Desimmie, Belete A.;
Zhao, Qi;
Sasaki, Tomoaki;
Burdick, Ryan C.;
Pathak, Vinay K.;
Anderson, Karen S.;
Xiong, Yong

Publication type:

Article

Comparison of capecitabine and 5-fluorouracil in chemoradiotherapy for locally advanced pancreatic cancer.

Published in:

2013

By:

Kim, Yeon-Joo;
Lee, Woo Jin;
Woo, Sang Myung;
Kim, Tae Hyun;
Han, Sung-Sik;
Kim, Bo Hyun;
Moon, Sung Ho;
Kim, Sang Soo;
Koh, Young Hwan;
Park, Sang-Jae;
Kim, Joo-Young;
Kim, Dae Yong;
Park, Joong-Won

Publication type:

journal article

Late-onset thymidine kinase 2 deficiency: a review of 18 cases.

Published in:

2019

By:

Domínguez-González, Cristina;
Hernández-Laín, Aurelio;
Rivas, Eloy;
Hernández-Voth, Ana;
Sayas Catalán, Javier;
Fernández-Torrón, Roberto;
Fuiza-Luces, Carmen;
García García, Jorge;
Morís, Germán;
Olivé, Montse;
Miralles, Frances;
Díaz-Manera, Jordi;
Caballero, Candela;
Méndez-Ferrer, Bosco;
Martí, Ramon;
García Arumi, Elena;
Badosa, María Carmen;
Esteban, Jesús;
Jimenez-Mallebrera, Cecilia;
Encinar, Alberto Blazquez

Publication type:

journal article

Recognition of the highly conserved YMDD region in the human immunodeficiency virus type 1 reverse transcriptase by HLA-A2-restricted cytotoxic T lymphocytes from an asymptomatic long-term nonprogressor.

Published in:

1996

By:

Harrer E;
Harrer T;
Barbosa P;
Feinberg M;
Johnson RP;
Buchbinder S;
Walker BD;
Harrer, E;
Harrer, T;
Barbosa, P;
Feinberg, M;
Johnson, R P;
Buchbinder, S;
Walker, B D

Publication type:

journal article

Regulation of TIMP-1 in Human Placenta and Fetal Membranes by lipopolysaccharide and demethylating agent 5-aza-2'-deoxycytidine.

Published in:

Reproductive Biology & Endocrinology, 2015, v. 13, p. 1, doi. 10.1186/s12958-015-0132-y

By:

Vincent, Zoë L.;
Mitchell, Murray D.;
Ponnampalam, Anna P.

Publication type:

Article

Deoxycytidine production by a metabolically engineered Escherichia coli strain.

Published in:

Microbial Cell Factories, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12934-015-0291-8

By:

Jin-Sook Kim;
Bong-Seong Koo;
Hyung-Hwan Hyun;
Hyeon-Cheol Lee

Publication type:

Article

CpG island hypermethylation-associated silencing of microRNAs promotes human endometrial cancer.

Published in:

Cancer Cell International, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1475-2867-13-44

By:

Bi-Lan Li;
Wen Lu;
Cong Lu;
Jun-jie Qu;
Ting-ting Yang;
Qin Yan;
Xiao-ping Wan

Publication type:

Article

Oromandibular dystonia: a serious side effect of capecitabine.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1132-1

By:

van Pelt-Sprangers, Melanie J. M.;
Geijteman, Eric C. T.;
Alsma, Jelmer;
Boere, Ingrid A.;
Mathijssen, Ron H. J.;
Schuit, Stephanie C. E.

Publication type:

Article

Targeting cMET with INC280 impairs tumour growth and improves efficacy of gemcitabine in a pancreatic cancer model.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1064-9

By:

Brandes, Franziska;
Schmidt, Katharina;
Wagner, Christine;
Redekopf, Julia;
Jürgen Schlitt, Hans;
Geissler, Edward Kenneth;
Lang, Sven Arke

Publication type:

Article

A randomized phase II study of capecitabine-based chemoradiation with or without bevacizumab in resectable locally advanced rectal cancer: clinical and biological features.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1053-z

By:

Salazar, Ramon;
Capdevila, Jaume;
Laquente, Berta;
Manzano, Jose Luis;
Pericay, Carles;
Villacampa, Mercedes Martínez;
López, Carlos;
Losa, Ferran;
Safont, Maria Jose;
Gómez, Auxiliadora;
Alonso, Vicente;
Escudero, Pilar;
Gallego, Javier;
Sastre, Javier;
Grávalos, Cristina;
Biondo, Sebastiano;
Palacios, Amalia;
Aranda, Enrique

Publication type:

Article

Phase II study of preoperative bevacizumab, capecitabine and radiotherapy for resectable locally-advanced rectal cancer.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1052-0

By:

García, Margarita;
Martinez-Villacampa, Mercedes;
Santos, Cristina;
Navarro, Valentin;
Teule, Alex;
Losa, Ferran;
Pisa, Aleydis;
Cambray, Maria;
Soler, Gemma;
Lema, Laura;
Kreisler, Esther;
Figueras, Agnes;
Juan, Xavier San;
Viñals, Francesc;
Biondo, Sebastiano;
Salazar, Ramon

Publication type:

Article

Multicenter Phase II study of FOLFOX or biweekly XELOX and Erbitux (cetuximab) as first-line therapy in patients with wild-type KRAS/BRAF metastatic colorectal cancer: The FLEET study.

Published in:

2015

By:

Soda, Hitoshi;
Maeda, Hiromichi;
Hasegawa, Junichi;
Takahashi, Takao;
Hazama, Shoichi;
Fukunaga, Mutsumi;
Kono, Emiko;
Kotaka, Masahito;
Sakamoto, Junichi;
Nagata, Naoki;
Oba, Koji;
Mishima, Hideyuki

Publication type:

journal article

Temporal evolution in caveolin 1 methylation levels during human esophageal carcinogenesis.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-345

By:

Zhe Jin;
Liang Wang;
Ziyi Cao;
Yulan Cheng;
Yan Gao;
Xianling Feng;
Si Chen;
Huimin Yu;
Wenjing Wu;
Zhenfu Zhao;
Ming Dong;
Xiaojing Zhang;
Jie Liu;
Xinmin Fan;
Yuriko Mori;
Meltzer, Stephen J.

Publication type:

Article

Demethylation of the miR-146a promoter by 5-Aza-2'-deoxycytidine correlates with delayed progression of castration-resistant prostate cancer.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-308

By:

Xiaolu Wang;
Haitao Gao;
Lixin Ren;
Junfei Gu;
Yanping Zhang;
Yong Zhang

Publication type:

Article

Bevacizumab with 5-fluorouracil, leucovorin, and oxaliplatin versus bevacizumab with capecitabine and oxaliplatin for metastatic colorectal carcinoma: results of a large registry-based cohort analysis.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-323

By:

Buchler, Tomas;
Pavlik, Tomas;
Melichar, Bohuslav;
Bortlicek, Zbynek;
Usiakova, Zuzana;
Dusek, Ladislav;
Kiss, Igor;
Kohoutek, Milan;
Benesova, Vera;
Vyzula, Rostislav;
Abrahamova, Jitka;
Obermannova, Radka

Publication type:

Article

Capecitabine in combination with oxaliplatin and bevacizumab (AXELOX) as 1st line treatment for fit and vulnerable elderly patients (aged >70 years) with metastatic colorectal cancer (mCRC): a multicenter phase II study of the Hellenic Oncology Research Group (HORG).

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-277

By:

Vamvakas, Lambros;
Matikas, Alexios;
Karampeazis, Athanasios;
Hatzidaki, Dora;
Kakolyris, Stelios;
Christophylakis, Charalampos;
Boukovinas, Ioannis;
Polyzos, Aris;
Georgoulias, Vassilis;
Souglakos, John

Publication type:

Article

Chk1 inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers.

Published in:

2014

By:

Bryant, Christopher;
Rawlinson, Rebecca;
Massey, Andrew J

Publication type:

journal article

Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine.

Published in:

2013

By:

Jørgensen, Charlotte L. T.;
Ejlertsen, Bent;
Bjerre, Karsten D.;
Balslev, Eva;
Nielsen, Dorte L.;
Nielsen, Kirsten V.

Publication type:

journal article

Phase I study evaluating the treatment of patients with locally advanced pancreatic cancer with carbon ion radiotherapy: the PHOENIX-01 trial.

Published in:

2013

By:

Combs, Stephanie E.;
Habermehl, Daniel;
Kieser, Meinhard;
Dreher, Constantin;
Werner, Jens;
Haselmann, Renate;
Jäkel, Oliver;
Jäger, Dirk;
Büchler, Markus W.;
Debus, Jürgen

Publication type:

journal article

Bifractionated CPT-11 with LV5FU2 infusion (FOLFIRI-3) in combination with bevacizumab: clinical outcomes in first-line metastatic colorectal cancers according to plasma angiopoietin-2 levels.

Published in:

2013

By:

Kim, Stefano;
Dobi, Erion;
Jary, Marine;
Monnien, Franck;
Curtit, Elsa;
NGuyen, Thierry;
Lakkis, Zaher;
Heyd, Bruno;
Fratte, Serge;
Cléau, Denis;
Lamfichekh, Najib;
Nerich, Virginie;
Guiu, Boris;
Demarchi, Martin;
Borg, Christophe

Publication type:

journal article

Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo.

Published in:

2013

By:

Montano, Ryan;
Thompson, Ruth;
Injae Chung;
Huagang Hou;
Nadeem Khan;
Eastman, Alan;
Chung, Injae;
Hou, Huagang;
Khan, Nadeem

Publication type:

journal article

Different Mutagenic Potential of HIV-1 Restriction Factors APOBEC3G and APOBEC3F Is Determined by Distinct Single-Stranded DNA Scanning Mechanisms.

Published in:

PLoS Pathogens, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.ppat.1004024

By:

Ara, Anjuman;
Love, Robin P.;
Chelico, Linda

Publication type:

Article

Functionalized Silver‐Ion‐Mediated α‐dC/β‐dC Hybrid Base Pairs with Exceptional Stability: α‐d‐5‐Iodo‐2′‐Deoxycytidine and Its Octadiynyl Derivative in Metal DNA.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 12, p. 3077, doi. 10.1002/chem.201805299

By:

Müller, Sebastian Lars;
Zhou, Xinglong;
Leonard, Peter;
Korzhenko, Oxana;
Daniliuc, Constantin;
Seela, Frank

Publication type:

Article

Dehalogenation of Halogenated Nucleobases and Nucleosides by Organoselenium Compounds.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 7, p. 1773, doi. 10.1002/chem.201805112

By:

Mondal, Santanu;
Mugesh, Govindasamy

Publication type:

Article