Works matching DE "ORGANIC cation transporters"

Results: 503

Combination of Periodontal Ligament Stem Cells and Metformin via Organic Cation Transporters for Periodontal Regeneration in Rats.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 663, doi. 10.3390/biom15050663

By:

Qiao, Qingchen;
Zhao, Zeqing;
Sun, Yaxi;
Wang, Jing;
Li, Xiaowei;
Zhang, Li;
Yang, Hao;
Zhang, Ning;
Zhang, Ke;
Bai, Yuxing

Publication type:

Article

Effects of cisplatin and acacetin on total antioxidant status, apoptosis and expression of OCTN3 in mouse testis.

Published in:

Biotechnic & Histochemistry, 2022, v. 97, n. 3, p. 185, doi. 10.1080/10520295.2021.1925347

By:

Ghanbari, Ali;
Jalili, Cyrus;
Abdolmaleki, Amir;
Shokri, Vahid

Publication type:

Article

Hydrogen Storage Materials: Room-Temperature Wet-Chemistry Approach toward Mixed-Metal Borohydrides.

Published in:

Angewandte Chemie, 2015, v. 127, n. 4, p. 1252, doi. 10.1002/ange.201408456

By:

Jaroń, Tomasz;
Orłowski, Piotr A.;
Wegner, Wojciech;
Fijałkowski, Karol J.;
Leszczyński, Piotr J.;
Grochala, Wojciech

Publication type:

Article

Coordination chemistry suggests that independently observed benefits of metformin and Zn2+ against COVID-19 are not independent.

Published in:

BioMetals, 2024, v. 37, n. 4, p. 983, doi. 10.1007/s10534-024-00590-5

By:

Lockwood, Thomas D.

Publication type:

Article

Intracellular uptake of an antitumor-active azole-bridged dinuclear platinum(II) complex in cisplatin-resistant tumor cells.

Published in:

BioMetals, 2016, v. 29, n. 6, p. 1075, doi. 10.1007/s10534-016-9978-5

By:

Kishimoto, Shuichi;
Yasuda, Megumi;
Suzuki, Ryosuke;
Fukushima, Shoji

Publication type:

Article

Thermostability-based binding assays reveal complex interplay of cation, substrate and lipid binding in the bacterial DASS transporter, VcINDY.

Published in:

Biochemical Journal, 2021, v. 478, n. 21, p. 3847, doi. 10.1042/BCJ20210061

By:

Sampson, Connor D. D.;
Fàbregas Bellavista, Cristina;
Stewart, Matthew J.;
Mulligan, Christopher

Publication type:

Article

Transporter tandems: precise tools for normalizing active transporter in the plasma membrane.

Published in:

Biochemical Journal, 2020, v. 477, n. 21, p. 4191, doi. 10.1042/BCJ20200666

By:

Tschirka, Julia;
Bach, Markus;
Kisis, Ilmars;
Lemmen, Julia;
Gnoth, Mark Jean;
Gründemann, Dirk

Publication type:

Article

The transport mechanism of P4 ATPase lipid flippases.

Published in:

Biochemical Journal, 2020, v. 477, n. 19, p. 3769, doi. 10.1042/BCJ20200249

By:

López-Marqués, Rosa L.;
Gourdon, Pontus;
Pomorski, Thomas Günther;
Palmgren, Michael

Publication type:

Article

The human organic cation transporter OCT1 and its role as a target for drug responses.

Published in:

Drug Metabolism Reviews, 2019, v. 51, n. 4, p. 389, doi. 10.1080/03602532.2019.1670204

By:

Brosseau, Nicolas;
Ramotar, Dindial

Publication type:

Article

Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation.

Published in:

Drug Metabolism Reviews, 2016, v. 48, n. 2, p. 139, doi. 10.1080/03602532.2016.1188936

By:

Hyrsova, Lucie;
Smutny, Tomas;
Trejtnar, Frantisek;
Pavek, Petr

Publication type:

Article

Inhibitory interaction of flavonoids with organic cation transporter 2 and their structure–activity relationships for predicting nephroprotective effects.

Published in:

Journal of Applied Toxicology, 2023, v. 43, n. 10, p. 1421, doi. 10.1002/jat.4474

By:

Tan, Huixin;
Wang, Fenghe;
Hu, Jiahuan;
Duan, Xiaoyan;
Bai, Wanting;
Wang, Xinbo;
Wang, Baolian;
Su, Yan;
Hu, Jinping

Publication type:

Article

An extended substrate spectrum of the proton organic cation antiporter and relation to other cation transporters.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 135, n. 6, p. 720, doi. 10.1111/bcpt.14090

By:

Ali Khan, Cauzar;
Kirsch, Nicolai;
Brockmöller, Jürgen;
Redeker, Kyra‐Elisa Maria

Publication type:

Article

Summarizing studies using constitutive genetic deficiency to investigate behavioural influences of uptake 2 monoamine transporters.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2023, v. 133, n. 5, p. 439, doi. 10.1111/bcpt.13810

By:

Weber, Brady L.;
Beaver, Jasmin N.;
Gilman, T. Lee

Publication type:

Article

No significant influence of OCT1 genotypes on the pharmacokinetics of morphine in adult surgical patients.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2022, v. 130, n. 1, p. 93, doi. 10.1111/bcpt.13667

By:

Kuhlmann, Ida;
Hjelmar Petersen, Rasmus;
Overgaard, Morten;
Dornonville de la Cour, Kenn;
Zwisler, Stine;
Bjerregaard Stage, Tore;
Hougaard Christensen, Mette Marie;
Bergmann, Troels K.;
Damkier, Per;
Gadegaard Jensen, Anders;
Nielsen, Flemming;
Brøsen, Kim

Publication type:

Article

Citrus fruit‐derived flavonoid naringenin and the expression of hepatic organic cation transporter 1 protein in diabetic rats treated with metformin.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 127, n. 3, p. 211, doi. 10.1111/bcpt.13407

By:

Mato Mofo, Edith P.;
Essop, M. Faadiel;
Owira, Peter M. O.

Publication type:

Article

Pharmacogenetics‐based population pharmacokinetic analysis of gabapentin in patients with chronic pain: Effect of OCT2 and OCTN1 gene polymorphisms.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2019, v. 124, n. 3, p. 266, doi. 10.1111/bcpt.13126

By:

Yamamoto, Priscila A.;
Benzi, Jhohann R. L.;
Azeredo, Francine J.;
Dach, Fabíola;
Ianhez Júnior, Edgar;
Zanelli, Cleslei F.;
Moraes, Natália V.

Publication type:

Article

Carnitine and γ-Butyrobetaine Stimulate Elimination of Meldonium due to Competition for OCTN2-mediated Transport.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2017, v. 120, n. 5, p. 450, doi. 10.1111/bcpt.12729

By:

Liepinsh, Edgars;
Makarova, Elina;
Sevostjanovs, Eduards;
Hartmane, Dace;
Cirule, Helena;
Zharkova‐Malkova, Olga;
Grinberga, Solveiga;
Dambrova, Maija

Publication type:

Article

Multidrug and toxin extrusion 1 and human organic cation transporter 1 polymorphisms in patients with castration-resistant prostate cancer receiving metformin (SAKK 08/09).

Published in:

Prostate Cancer & Prostatic Diseases, 2015, v. 18, n. 2, p. 167, doi. 10.1038/pcan.2015.8

By:

Joerger, M.;
van Schaik, R. H. N.;
Becker, M. L.;
Hayoz, S.;
Pollak, M.;
Cathomas, R.;
Winterhalder, R.;
Gillessen, S.;
Rothermundt, C.

Publication type:

Article

Risk factors for cisplatin-induced acute kidney injury: A pilot study on the usefulness of genetic variants for predicting nephrotoxicity in clinical practice.

Published in:

Molecular & Clinical Oncology, 2020, v. 13, n. 5, p. N.PAG, doi. 10.3892/mco.2020.2127

By:

Oda, Hiroyasu;
Mizuno, Toshiro;
Ikejiri, Makoto;
Nakamura, Maki;
Tsunoda, Akira;
Ishihara, Mikiya;
Saito, Kanako;
Tamaru, Satoshi;
Yamashita, Yoshiki;
Nishimura, Yuhei;
Nakatani, Kaname;
Katayama, Naoyuki

Publication type:

Article

Is N 1-Methylnicotinamide a Good Organic Cation Transporter 2 (OCT2) Biomarker?

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 2, p. 80, doi. 10.3390/metabo15020080

By:

Ailabouni, Anoud Sameer;
Vijaywargi, Gautam;
Subash, Sandhya;
Singh, Dilip Kumar;
Gaborik, Zsuzsanna;
Prasad, Bhagwat

Publication type:

Article

Regulation Mechanisms of Expression and Function of Organic Cation Transporter 1.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.607613

By:

Ciarimboli, Giuliano

Publication type:

Article

Cellular Uptake of Psychostimulants – Are High- and Low-Affinity Organic Cation Transporters Drug Traffickers?

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.609811

By:

Jensen, Ole;
Rafehi, Muhammad;
Gebauer, Lukas;
Brockmöller, Jürgen

Publication type:

Article

The Discovery of Insulin-Regulated Aminopeptidase (IRAP) Inhibitors: A Literature Review.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.585838

By:

Georgiadis, Dimitris;
Ziotopoulou, Angeliki;
Kaloumenou, Eleni;
Lelis, Angelos;
Papasava, Antonia

Publication type:

Article

Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A.

Published in:

Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01297

By:

Rafehi, Muhammad;
Faltraco, Frank;
Matthaei, Johannes;
Prukop, Thomas;
Jensen, Ole;
Grytzmann, Aileen;
Blome, Felix G.;
Berger, Ralf Günter;
Krings, Ulrich;
Vormfelde, Stefan V.;
Tzvetkov, Mladen V.;
Brockmöller, Jürgen

Publication type:

Article

Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats.

Published in:

Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01243

By:

Patel, Oelfah;
Muller, Christo J.F.;
Joubert, Elizabeth;
Rosenkranz, Bernd;
Taylor, Malcolm J.C.;
Louw, Johan;
Awortwe, Charles

Publication type:

Article

Renal PET-imaging with C-metformin in a transgenic mouse model for chronic kidney disease.

Published in:

EJNMMI Research, 2016, v. 6, n. 1, p. 1, doi. 10.1186/s13550-016-0211-x

By:

Pedersen, Lea;
Jensen, Jonas;
Wogensen, Lise;
Munk, Ole;
Jessen, Niels;
Frøkiær, Jørgen;
Jakobsen, Steen

Publication type:

Article

Genetic polymorphisms of OCT- 1 confer susceptibility to severe progression of primary biliary cirrhosis in Japanese patients.

Published in:

Journal of Gastroenterology, 2014, v. 49, n. 2, p. 332, doi. 10.1007/s00535-013-0795-0

By:

Ohishi, Yuki;
Nakamuta, Makoto;
Ishikawa, Naoko;
Saitoh, Ohki;
Nakamura, Hitomi;
Aiba, Yoshihiro;
Komori, Atsumasa;
Migita, Kiyoshi;
Yatsuhashi, Hiroshi;
Fukushima, Nobuyoshi;
Kohjima, Motoyuki;
Yoshimoto, Tsuyoshi;
Fukuizumi, Kunitaka;
Ishibashi, Makoto;
Nishino, Takashi;
Shirabe, Ken;
Taketomi, Akinobu;
Maehara, Yoshihiko;
Ishibashi, Hiromi;
Nakamura, Minoru

Publication type:

Article

Arabidopsis K+ transporter HAK5-mediated high-affinity root K+ uptake is regulated by protein kinases CIPK1 and CIPK9.

Published in:

Journal of Experimental Botany, 2020, v. 71, n. 16, p. 5053, doi. 10.1093/jxb/eraa212

By:

Lara, Alberto;
Ródenas, Reyes;
Andrés, Zaida;
Martínez, Vicente;
Quintero, Francisco J;
Nieves-Cordones, Manuel;
Botella, M Angeles;
Rubio, Francisco

Publication type:

Article

Natural variation in the expression of ORGANIC CATION TRANSPORTER 1 affects root length responses to cadaverine in Arabidopsis.

Published in:

Journal of Experimental Botany, 2015, v. 66, n. 3, p. 853, doi. 10.1093/jxb/eru444

By:

Strohm, Allison K.;
Vaughn, Laura M.;
Masson, Patrick H.

Publication type:

Article

Enhanced stability of low temperature processed perovskite solar cells via augmented polaronic intensity of hole transporting layer.

Published in:

Physica Status Solidi - Rapid Research Letters, 2016, v. 10, n. 12, p. 882, doi. 10.1002/pssr.201600315

By:

Arafat Mahmud, Md.;
Kumar Elumalai, NaveEN;
Baishakhi Upama, Mushfika;
Wang, Dian;
Haque, Faiazul;
Wright, Matthew;
Howe Chan, Kah;
Xu, ChENg;
Uddin, Ashraf

Publication type:

Article

Genetic Variants of SLC22A1 rs628031 and rs622342 and Glycemic Control in T2DM Patients from Northern Mexico.

Published in:

Genes, 2025, v. 16, n. 2, p. 139, doi. 10.3390/genes16020139

By:

Moreno-González, Janette G.;
Reza-López, Sandra A.;
González-Rodríguez, Everardo;
Siqueiros-Cendón, Tania Samanta;
Escareño Contreras, Alfonso;
Rascón-Cruz, Quintín;
Leal-Berumen, Irene

Publication type:

Article

Identification of Novel Intronic SNPs in Transporter Genes Associated with Metformin Side Effects.

Published in:

Genes, 2023, v. 14, n. 8, p. 1609, doi. 10.3390/genes14081609

By:

Schweighofer, Natascha;
Strasser, Moritz;
Obermayer, Anna;
Trummer, Olivia;
Sourij, Harald;
Sourij, Caren;
Obermayer-Pietsch, Barbara

Publication type:

Article

Role of OCT1 in hepatocellular carcinoma.

Published in:

OncoTargets & Therapy, 2019, v. 12, p. 6013, doi. 10.2147/OTT.S212088

By:

Li, Jingguo;
Yang, Zhengyi;
Tuo, Biguang

Publication type:

Article

Significance of downregulation of renal organic cation transporter (SLC47A1) in cisplatin-induced proximal tubular injury.

Published in:

OncoTargets & Therapy, 2015, v. 8, p. 1701, doi. 10.2147/OTT.S86743

By:

Tomohiro Mizuno;
Waichi Sato;
Kazuhiro Ishikawa;
Yuki Terao;
Kazuo Takahashi;
Yukihiro Noda;
Yukio Yuzawa;
Tadashi Nagamatsu

Publication type:

Article

Genetic polymorphism of organic cation transporter 2 (OCT2) and its effects on the pharmacokinetics and pharmacodynamics of Metformin: a narrative review.

Published in:

Egyptian Journal of Medical Human Genetics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s43042-023-00388-z

By:

Borra, Swathi Swaroopa;
Jane, Niva Rose;
Palaniappan, Dhivyaprasath;
Subramanian, Rupakrishnan;
Patankar, Mithila Amar;
Krishnamoorthy, Sadagoban Gopal;
Parthasarathy, Arun Kanniyappan

Publication type:

Article

Antituberculosis potential of borrelidin derivatives: An in silico molecular docking and molecular dynamic approach.

Published in:

Thai Journal of Pharmaceutical Sciences, 2025, v. 49, n. 1, p. 1

By:

Ernawati, Teni;
Ramadhan, Donny;
Hermawan, Faris;
Wulyoadi, Sasmito;
Marwoto, Bambang;
Wibisana, Ahmad;
Srijanto, Bambang

Publication type:

Article

Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.

Published in:

PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0214862

By:

Nishizawa, Kei;
Yoda, Noriaki;
Morokado, Fumi;
Komori, Hisakazu;
Nakanishi, Takeo;
Tamai, Ikumi

Publication type:

Article

Recent advances in radiotracers targeting norepinephrine transporter: structural development and radiolabeling improvements.

Published in:

Journal of Neural Transmission, 2020, v. 127, n. 6, p. 851, doi. 10.1007/s00702-020-02180-4

By:

Chen, Xinyu;
Kudo, Takashi;
Lapa, Constantin;
Buck, Andreas;
Higuchi, Takahiro

Publication type:

Article

9-Methyl-β-carboline inhibits monoamine oxidase activity and stimulates the expression of neurotrophic factors by astrocytes.

Published in:

Journal of Neural Transmission, 2020, v. 127, n. 7, p. 999, doi. 10.1007/s00702-020-02189-9

By:

Keller, Sebastian;
Polanski, Witold Henryk;
Enzensperger, Christoph;
Reichmann, Heinz;
Hermann, Andreas;
Gille, Gabriele

Publication type:

Article

The discovery and development of rasagiline as a new anti-Parkinson medication.

Published in:

Journal of Neural Transmission, 2020, v. 127, n. 2, p. 125, doi. 10.1007/s00702-020-02142-w

By:

Finberg, John P. M.

Publication type:

Article

Fine mapping of a thrips resistance QTL in Capsicum and the role of diterpene glycosides in the underlying mechanism.

Published in:

Theoretical & Applied Genetics, 2021, v. 134, n. 5, p. 1557, doi. 10.1007/s00122-021-03790-6

By:

van Haperen, Pauline;
Voorrips, Roeland E.;
van Kaauwen, Martijn;
van Eekelen, Henriëtte D. L. M.;
de Vos, Ric C. H.;
van Loon, Joop J. A.;
Vosman, Ben

Publication type:

Article

Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-K.

Published in:

Xenobiotica, 2022, v. 52, n. 9-11, p. 997, doi. 10.1080/00498254.2022.2129517

By:

Yamamura, Naotoshi;
Mikkaichi, Tsuyoshi;
Itokawa, Ken-ichi;
Hoshi, Misa;
Damme, Katja;
Geigner, Stefanie;
Baumhauer, Christine

Publication type:

Article

Rutaecarpine enhances the anti-diabetic activity and hepatic distribution of metformin via up-regulation of Oct1 in diabetic rats.

Published in:

Xenobiotica, 2021, v. 51, n. 7, p. 818, doi. 10.1080/00498254.2021.1926573

By:

Song, Xian-Mei;
Li, Bing-Jie;
Zhang, Yan-Yan;
Ge, Wen-Jing;
Zhang, She-Feng;
Cui, Wei-Feng;
Li, Geng-Sheng;
Liang, Rui-Feng

Publication type:

Article

Drug–drug interaction potential and clinical pharmacokinetics of enerisant, a novel potent and selective histamine H3 receptor antagonist.

Published in:

Xenobiotica, 2021, v. 51, n. 7, p. 786, doi. 10.1080/00498254.2021.1918361

By:

Terasaka, Shuichi;
Hachiuma, Kenji;
Mano, Yoko;
Onishi, Koichi;
Kitajima, Iwao;
Nishino, Izumi;
Endo, Hiromi

Publication type:

Article

Differential in vitro interactions of the Janus kinase inhibitor ruxolitinib with human SLC drug transporters.

Published in:

Xenobiotica, 2021, v. 51, n. 4, p. 467, doi. 10.1080/00498254.2021.1875516

By:

Bruyère, Arnaud;
Le Vée, Marc;
Jouan, Elodie;
Molez, Stephanie;
Nies, Anne T.;
Fardel, Olivier

Publication type:

Article

Inhibitory effect of sixteen pharmaceutical excipients on six major organic cation and anion uptake transporters.

Published in:

Xenobiotica, 2021, v. 51, n. 1, p. 95, doi. 10.1080/00498254.2020.1783720

By:

Ma, Ruicong;
Li, Gentao;
Wang, Xue;
Bi, Yajuan;
Zhang, Youcai

Publication type:

Article

Involvement of organic anion-transporting polypeptides and organic cation transporter in the hepatic uptake of jatrorrhizine.

Published in:

Xenobiotica, 2020, v. 50, n. 4, p. 479, doi. 10.1080/00498254.2019.1651921

By:

Liang, Rui-Feng;
Ge, Wen-Jing;
Song, Xian-Mei;
Zhang, Jun-Ping;
Cui, Wei-Feng;
Zhang, She-Feng;
Li, Geng-Sheng

Publication type:

Article

Jatrorrhizine reduces 5-HT and NE uptake via inhibition of uptake-2 transporters and produces antidepressant-like action in mice.

Published in:

Xenobiotica, 2019, v. 49, n. 10, p. 1237, doi. 10.1080/00498254.2018.1542188

By:

Sun, Siyuan;
Zhou, Sisi;
Lei, Shaowei;
Zhu, Shujie;
Wang, Kai;
Jiang, Huidi;
Zhou, Hui

Publication type:

Article

Interactions of organophosphorus pesticides with solute carrier (SLC) drug transporters.

Published in:

Xenobiotica, 2019, v. 49, n. 3, p. 363, doi. 10.1080/00498254.2018.1442030

By:

Chedik, Lisa;
Bruyere, Arnaud;
Fardel, Olivier

Publication type:

Article

Comparison of baseline method and DSC measurement for determining phase fractions.

Published in:

Materials Science & Technology, 2012, v. 28, n. 12, p. 1420, doi. 10.1179/1743284712Y.0000000092

By:

Xu, J F;
Liu, F;
Zhang, D;
Zhang, K

Publication type:

Article