Works matching DE "CONNECTIN"

Results: 340

Motion of a polymer globule with Vicsek-like activity: from super-diffusive to ballistic behavior.

Published in:

Soft Materials, 2021, v. 19, n. 3, p. 306, doi. 10.1080/1539445X.2021.1909064

By:

Paul, Subhajit;
Majumder, Suman;
Janke, Wolfhard

Publication type:

Article

Short-interval intracortical inhibition of the biceps brachii in chronic-resistance versus non-resistance-trained individuals.

Published in:

Experimental Brain Research, 2019, v. 237, n. 11, p. 3023, doi. 10.1007/s00221-019-05649-1

By:

Lahouti, Behzad;
Lockyer, Evan J.;
Wiseman, Shawn;
Power, Kevin E.;
Button, Duane C.

Publication type:

Article

TITINdb--a computational tool to assess titin's role as a disease gene.

Published in:

Bioinformatics, 2017, v. 33, n. 21, p. 3482, doi. 10.1093/bioinformatics/btx424

By:

Laddach, Anna;
Gautel, Mathias;
Fraternali, Franca

Publication type:

Article

Optimized Conditions for the Long-Term Maintenance of Precision-Cut Murine Myocardium in Biomimetic Tissue Culture.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 2, p. 171, doi. 10.3390/bioengineering10020171

By:

Cao-Ehlker, Xiaochun;
Fischer, Carola;
Lu, Kun;
Bruegmann, Tobias;
Sasse, Philipp;
Dendorfer, Andreas;
Tomasi, Roland

Publication type:

Article

Protein‐extending ACTN2 frameshift variants cause variable myopathy phenotypes by protein aggregation.

Published in:

Annals of Clinical & Translational Neurology, 2024, v. 11, n. 9, p. 2392, doi. 10.1002/acn3.52154

By:

Ranta‐aho, Johanna;
Felice, Kevin J.;
Jonson, Per Harald;
Sarparanta, Jaakko;
Yvorel, Cédric;
Harzallah, Ines;
Touraine, Renaud;
Pais, Lynn;
Austin‐Tse, Christina A.;
Ganesh, Vijay S.;
O'Leary, Melanie C.;
Rehm, Heidi L.;
Hehir, Michael K.;
Subramony, Sub;
Wu, Qian;
Udd, Bjarne;
Savarese, Marco

Publication type:

Article

Human Leukocyte Antigen Class II associations in late‐onset Myasthenia Gravis.

Published in:

Annals of Clinical & Translational Neurology, 2021, v. 8, n. 3, p. 656, doi. 10.1002/acn3.51309

By:

Spagni, Gregorio;
Todi, Laura;
Monte, Gabriele;
Valentini, Mariagrazia;
Di Sante, Gabriele;
Damato, Valentina;
Marino, Mariapaola;
Evoli, Amelia;
Lantieri, Francesca;
Provenzano, Carlo

Publication type:

Article

A novel long non-coding RNA TTN-AS1/microRNA-589-5p/FOXP1 positive feedback loop increases the proliferation, migration and invasion of pancreatic cancer cell lines.

Published in:

Oncology Letters, 2021, v. 22, n. 5, p. N.PAG, doi. 10.3892/ol.2021.13055

By:

Zhao, Jing;
Wu, Fang;
Yang, Jun

Publication type:

Article

Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.

Published in:

Life (2075-1729), 2023, v. 13, n. 2, p. 445, doi. 10.3390/life13020445

By:

Cafournet, Cérane;
Zanin, Sofia;
Guimier, Anne;
Hully, Marie;
Assouline, Zahra;
Barcia, Giulia;
de Lonlay, Pascale;
Steffann, Julie;
Munnich, Arnold;
Bonnefont, Jean-Paul;
Rötig, Agnès;
Ruzzenente, Benedetta;
Metodiev, Metodi D.

Publication type:

Article

Cyclic Stretch Force Induces Periodontal Ligament Cells to Secrete Exosomes That Suppress IL-1β Production Through the Inhibition of the NF-κB Signaling Pathway in Macrophages.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01310

By:

Wang, Zhuyu;
Maruyama, Kentarou;
Sakisaka, Yukihiko;
Suzuki, Shigeki;
Tada, Hiroyuki;
Suto, Mizuki;
Saito, Masahiro;
Yamada, Satoru;
Nemoto, Eiji

Publication type:

Article

Social, Genetics and Histopathological Factors Related to Titin (TTN) Gene Mutation and Survival in Women with Ovarian Serous Cystadenocarcinoma: Bioinformatics Analysis.

Published in:

Genes, 2023, v. 14, n. 5, p. 1092, doi. 10.3390/genes14051092

By:

Gomes, Fabiana de Campos;
Figueiredo, Eric Renato Lima;
Araújo, Ediane Nunes De;
Andrade, Edila Monteiro De;
Carneiro, Carlos Diego Lisbôa;
Almeida, Gabriel Mácola De;
Dias, Helana Augusta Andrade Leal;
Teixeira, Lucélia Inoue Bispo;
Almeida, Manuela Trindade;
Farias, Mariusa Fernandes De;
Linhares, Natália Albim;
Fonseca, Natasha Lima Da;
Pereira, Yago Dos Santos;
Melo-Neto, João Simão de

Publication type:

Article

Array Comparative Genomic Hybridisation and Droplet Digital PCR Uncover Recurrent Copy Number Variation of the TTN Segmental Duplication Region.

Published in:

Genes, 2022, v. 13, n. 5, p. 905, doi. 10.3390/genes13050905

By:

Sagath, Lydia;
Lehtokari, Vilma-Lotta;
Pelin, Katarina;
Kiiski, Kirsi

Publication type:

Article

Molecular Pathways Associated with Kallikrein 6 Overexpression in Colorectal Cancer.

Published in:

Genes, 2021, v. 12, n. 5, p. 749, doi. 10.3390/genes12050749

By:

Pandey, Ritu;
Zhou, Muhan;
Chen, Yuliang;
Darmoul, Dalila;
Kisiel, Conner C.;
Nfonsam, Valentine N.;
Ignatenko, Natalia A.;
Korinek, Vladimir;
Wnuk, Maciej

Publication type:

Article

Special Issue "Cardiovascular Genetics".

Published in:

2021

By:

Brodehl, Andreas;
Milting, Hendrik;
Gerull, Brenda

Publication type:

Editorial

Characterization of TTN Novex Splicing Variants across Species and the Role of RBM20 in Novex-Specific Exon Splicing.

Published in:

Genes, 2018, v. 9, n. 2, p. 86, doi. 10.3390/genes9020086

By:

Chen, Zhilong;
Song, Jiangping;
Chen, Liang;
Zhu, Chaoqun;
Cai, Hanfang;
Sun, Mingming;
Stern, Allysa;
Mozdziak, Paul;
Ge, Ying;
Means, Warrie J.;
Guo, Wei

Publication type:

Article

AHNAK2 Promotes Migration, Invasion, and Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Cells via the TGF-β/Smad3 Pathway.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 12893, doi. 10.2147/OTT.S281517

By:

Liu, Gang;
Guo, Zhongliang;
Zhang, Qian;
Liu, Zhongmin;
Zhu, Dongyi

Publication type:

Article

Ultra-stable Biomembrane Force Probe to Characterize Strong Protein-Protein Interactions on a Living Cell.

Published in:

Molecular & Cellular Biomechanics, 2019, v. 16, p. 109, doi. 10.32604/mcb.2019.07634

By:

Chenyi An;
Wei Chen

Publication type:

Article

Whole-exome sequencing reveals doubly novel heterozygous Myosin Binding Protein C and Titin mutations in a Chinese patient with severe dilated cardiomyopathy.

Published in:

2018

By:

Fan, Liang-Liang;
Chen, Ya-Qin;
Huang, Hao;
Jin, Jie-Yuan;
Li, Jing-Jing;
Tan, Zhi-Ping

Publication type:

journal article

Functional abnormalities in induced Pluripotent Stem Cell-derived cardiomyocytes generated from titin-mutated patients with dilated cardiomyopathy.

Published in:

PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0205719

By:

Schick, Revital;
Mekies, Lucy N.;
Shemer, Yuval;
Eisen, Binyamin;
Hallas, Tova;
Ben Jehuda, Ronen;
Ben-Ari, Meital;
Szantai, Agnes;
Willi, Lubna;
Shulman, Rita;
Gramlich, Michael;
Pane, Luna Simona;
My, Ilaria;
Freimark, Dov;
Murgia, Marta;
Santamaria, Gianluca;
Gherghiceanu, Mihaela;
Arad, Michael;
Moretti, Alessandra;
Binah, Ofer

Publication type:

Article

Truncations of the titin Z-disc predispose to a heart failure with preserved ejection phenotype in the context of pressure overload.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0201498

By:

Ye, Lei;
Su, Liping;
Wang, Chenxu;
Loo, Szejie;
Tee, Guizhen;
Tan, Shihua;
Khin, Sandar Win;
Ko, Shijie;
Su, Boyang;
Cook, Stuart A.

Publication type:

Article

The effects of a skeletal muscle titin mutation on walking in mice.

Published in:

Journal of Comparative Physiology A: Neuroethology, Sensory, Neural & Behavioral Physiology, 2017, v. 203, n. 1, p. 67, doi. 10.1007/s00359-016-1137-5

By:

Pace, Cinnamon;
Mortimer, Sarah;
Monroy, Jenna;
Nishikawa, Kiisa

Publication type:

Article

Clinical characteristics and prognosis of Chinese patients with hereditary transthyretin amyloid cardiomyopathy.

Published in:

2019

By:

He, Shan;
Tian, Zhuang;
Guan, Hongzhi;
Li, Jian;
Fang, Quan;
Zhang, Shuyang

Publication type:

journal article

RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.

Published in:

Nature Medicine, 2012, v. 18, n. 5, p. 766, doi. 10.1038/nm.2693

By:

Guo, Wei;
Schafer, Sebastian;
Greaser, Marion L;
Radke, Michael H;
Liss, Martin;
Govindarajan, Thirupugal;
Maatz, Henrike;
Schulz, Herbert;
Li, Shijun;
Parrish, Amanda M;
Dauksaite, Vita;
Vakeel, Padmanabhan;
Klaassen, Sabine;
Gerull, Brenda;
Thierfelder, Ludwig;
Regitz-Zagrosek, Vera;
Hacker, Timothy A;
Saupe, Kurt W;
Dec, G William;
Ellinor, Patrick T

Publication type:

Article

King of hearts: a splicing factor rules cardiac proteins.

Published in:

Nature Medicine, 2012, v. 18, n. 5, p. 660, doi. 10.1038/nm.2762

By:

Linke, Wolfgang A;
Bücker, Sandra

Publication type:

Article

Letter to the editor regarding the article "A case of hypertrophic and dilated cardiomyopathic sudden cardiac death: de novo mutation in TTN and SGCD genes".

Published in:

2017

By:

Ergören, Mahmut Çerkez;
Temel, Sehime Gülsün;
Baydar, Çetin Lütfi

Publication type:

Letter to the Editor

A hypertrophic and dilated cardiomyopathic sudden cardiac death case; de novo mutations in TTN and SGCD genes.

Published in:

2016

By:

Baydar, Çetin Lütfi;
Özen, Minel

Publication type:

Case Study

Urinary Titin on the First Postoperative Day Predicts Long-Term Skeletal Muscle Loss in Patients with Gastroenterological Cancer.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 5, p. 2026, doi. 10.3390/ijms26052026

By:

Kyomen, Momoko;
Tatsumi, Ayako;
Tsutsumi, Rie;
Izumi-Mishima, Yuna;
Hyodo, Mizusa;
Tanaka, Eiji;
Iguchi, Kohta;
Taura, Kojiro;
Terajima, Hiroaki;
Honjo, Sachiko;
Hamasaki, Akihiro;
Nomura, Kazuhiro;
Sakaue, Hiroshi

Publication type:

Article

Differential expression of genes participating in cardiomyocyte electrophysiological remodeling via membrane ionic mechanisms and Ca2+-handling in human heart failure.

Published in:

Molecular & Cellular Biochemistry, 2020, v. 463, n. 1/2, p. 33, doi. 10.1007/s11010-019-03626-4

By:

Kepenek, Eda Seyma;
Ozcinar, Evren;
Tuncay, Erkan;
Akcali, Kamil Can;
Akar, Ahmet Ruchan;
Turan, Belma

Publication type:

Article

Consecutive SSCs increase the SSC effect in skinned rat muscle fibres.

Published in:

Pflügers Archiv: European Journal of Physiology, 2025, v. 477, n. 6, p. 873, doi. 10.1007/s00424-025-03088-2

By:

Elst, Tobias;
Weidner, Sven;
Tomalka, André;
Hahn, Daniel;
Paternoster, Florian Kurt;
Seiberl, Wolfgang;
Siebert, Tobias

Publication type:

Article

Impact of lengthening velocity on the generation of eccentric force by slow-twitch muscle fibers in long stretches.

Published in:

Pflügers Archiv: European Journal of Physiology, 2024, v. 476, n. 10, p. 1517, doi. 10.1007/s00424-024-02991-4

By:

Weidner, Sven;
Tomalka, André;
Rode, Christian;
Siebert, Tobias

Publication type:

Article

Eccentric muscle contractions: from single muscle fibre to whole muscle mechanics.

Published in:

Pflügers Archiv: European Journal of Physiology, 2023, v. 475, n. 4, p. 421, doi. 10.1007/s00424-023-02794-z

By:

Tomalka, André

Publication type:

Article

Advances in understanding the state of titin truncation variants in dilated cardiomyopathy.

Published in:

2022

By:

Solaro, R. John

Publication type:

Editorial

Sarcomeric mutations in cardiac diseases.

Published in:

2019

By:

Harris, Samantha P.;
de Tombe, Pieter P.

Publication type:

Editorial

Untying the knot: protein quality control in inherited cardiomyopathies.

Published in:

Pflügers Archiv: European Journal of Physiology, 2019, v. 471, n. 5, p. 795, doi. 10.1007/s00424-018-2194-0

By:

Dorsch, Larissa M.;
Schuldt, Maike;
Knežević, Dora;
Wiersma, Marit;
Kuster, Diederik W. D.;
van der Velden, Jolanda;
Brundel, Bianca J. J. M.

Publication type:

Article

Titin mutations and muscle disease.

Published in:

Pflügers Archiv: European Journal of Physiology, 2019, v. 471, n. 5, p. 673, doi. 10.1007/s00424-019-02272-5

By:

Kellermayer, Dalma;
Smith, John E.;
Granzier, Henk

Publication type:

Article

Three perspectives on the molecular basis of hypercontractility caused by hypertrophic cardiomyopathy mutations.

Published in:

Pflügers Archiv: European Journal of Physiology, 2019, v. 471, n. 5, p. 701, doi. 10.1007/s00424-019-02259-2

By:

Spudich, James A.

Publication type:

Article

Allelic imbalance and haploinsufficiency in MYBPC3-linked hypertrophic cardiomyopathy.

Published in:

Pflügers Archiv: European Journal of Physiology, 2019, v. 471, n. 5, p. 781, doi. 10.1007/s00424-018-2226-9

By:

Glazier, Amelia A.;
Thompson, Andrea;
Day, Sharlene M.

Publication type:

Article

Expanding the MuRF1 Universe with Quantitative Ubiquitylomics.

Published in:

Function, 2021, v. 2, n. 6, p. 1, doi. 10.1093/function/zqab058

By:

Goodman, Craig A;
Parker, Benjamin L;
Gregorevic, Paul

Publication type:

Article

DNA barcode-based survey documents underestimated diversity and intricate phylogeographic patterns of aquatic Heteroptera in an endangered Balkan biodiversity hotspot: ancient Lake Skadar basin.

Published in:

Biodiversity & Conservation, 2023, v. 32, n. 12, p. 4111, doi. 10.1007/s10531-023-02686-9

By:

Rewicz, Tomasz;
Tończyk, Grzegorz;
Trębicki, Łukasz;
Gadawski, Piotr;
Mamos, Tomasz;
Pešić, Vladimir;
Zawal, Andrzej;
Grabowski, Michał

Publication type:

Article

Cocaine, amphetamine, or titin: Unraveling the genetic underpinnings of dilated cardiomyopathy.

Published in:

2024

By:

Panjiyar, Binay Kumar;
Changlani, Nikita;
Medina, Clarisa;
Trevino, Lisa R.

Publication type:

Case Study

Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.58313

By:

Filomena, Maria Carmela;
Yamamoto, Daniel L.;
Carullo, Pierluigi;
Medvedev, Roman;
Ghisleni, Andrea;
Piroddi, Nicoletta;
Scellini, Beatrice;
Crispino, Roberta;
D'Autilia, Francesca;
Jianlin Zhang;
Felicetta, Arianna;
Nemska, Simona;
Serio, Simone;
Tesi, Chiara;
Catalucci, Daniele;
Linke, Wolfgang A.;
Polishchuk, Roman;
Poggesi, Corrado;
Gautel, Mathias;
Bang, Marie-Louise

Publication type:

Article

Conformational changes in twitchin kinase in vivo revealed by FRET imaging of freely moving C. elegans.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.66862

By:

Porto, Daniel;
Matsunaga, Yohei;
Franke, Barbara;
Williams, Rhys M.;
Hiroshi Qadota;
Mayans, Olga;
Benian, Guy M.;
Hang Lu

Publication type:

Article

Pressure Overload by Transverse Aortic Constriction Induces Maladaptive Hypertrophy in a Titin-Truncated Mouse Model.

Published in:

2015

By:

Zhou, Qifeng;
Kesteven, Scott;
Wu, Jianxin;
Aidery, Parwez;
Gawaz, Meinrad;
Gramlich, Michael;
Feneley, Michael P.;
Harvey, Richard P.

Publication type:

journal article

Successful heart transplant in a child with congenital core myopathy and delayed‐onset restrictive cardiomyopathy due to recessive mutations in the titin (TTN) gene.

Published in:

Pediatric Transplantation, 2023, v. 27, n. 6, p. 1, doi. 10.1111/petr.14561

By:

Wacker, Julie;
Di Bernardo, Stefano;
Lobrinus, Johannes Alexander;
Jungbluth, Heinz;
Gautel, Mathias;
Beghetti, Maurice;
Fluss, Joel

Publication type:

Article

E3-ligase knock down revealed differential titin degradation by autopagy and the ubiquitin proteasome system.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00618-7

By:

Müller, Erik;
Salcan, Senem;
Bongardt, Sabine;
Barbosa, David Monteiro;
Krüger, Martina;
Kötter, Sebastian

Publication type:

Article

Computational analysis of the flexibility in the disordered linker region connecting LIM domains in cysteine-glycine-rich protein.

Published in:

Frontiers in Genetics, 2023, v. 14, p. 1, doi. 10.3389/fgene.2023.1134509

By:

Chauhan, Pankaj Kumar;
Sowdhamini, R.

Publication type:

Article

Altered mechanical properties of titin immunoglobulin domain 27 in the presence of calcium.

Published in:

European Biophysics Journal, 2013, v. 42, n. 4, p. 301, doi. 10.1007/s00249-012-0875-8

By:

DuVall, Michael;
Gifford, Jessica;
Amrein, Matthias;
Herzog, Walter

Publication type:

Article

Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model of phospholamban R14del cardiomyopathy.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27461-8

By:

Kamel, S. M.;
van Opbergen, C. J. M.;
Koopman, C. D.;
Verkerk, A. O.;
Boukens, B. J. D.;
de Jonge, B.;
Onderwater, Y. L.;
van Alebeek, E.;
Chocron, S.;
Polidoro Pontalti, C.;
Weuring, W. J.;
Vos, M. A.;
de Boer, T. P.;
van Veen, T. A. B.;
Bakkers, J.

Publication type:

Article

Microbial production of megadalton titin yields fibers with advantageous mechanical properties.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25360-6

By:

Bowen, Christopher H.;
Sargent, Cameron J.;
Wang, Ao;
Zhu, Yaguang;
Chang, Xinyuan;
Li, Jingyao;
Mu, Xinyue;
Galazka, Jonathan M.;
Jun, Young-Shin;
Keten, Sinan;
Zhang, Fuzhong

Publication type:

Article

The Giant Protein Titin's Role in Cardiomyopathy: Genetic, Transcriptional, and Post-translational Modifications of TTN and Their Contribution to Cardiac Disease.

Published in:

Frontiers in Physiology, 2019, v. 10, p. 1, doi. 10.3389/fphys.2019.01436

By:

Tharp, Charles A.;
Haywood, Mary E.;
Sbaizero, Orfeo;
Taylor, Matthew R. G.;
Mestroni, Luisa

Publication type:

Article

Neurodegenerative Disease–Associated Variants in TREM2 Destabilize the Apical Ligand-Binding Region of the Immunoglobulin Domain.

Published in:

Frontiers in Neurology, 2019, v. 10, p. 1, doi. 10.3389/fneur.2019.01252

By:

Dean, Hunter B.;
Roberson, Erik D.;
Song, Yuhua

Publication type:

Article