Early Postoperative Effects of Uncomplicated Phacoemulsification on Corneal Parameters in Patients with Pseudoexfoliation Syndrome.

Ekici, Eren; Keleş, Ali; Karaman, Süleyman Korhan

Introduction: To compare early postoperative effects of uncomplicated phacoemulsification surgery on corneal endothelial cells and thickness in patients with pseudoexfoliation syndrome (PEX). Methods: One eye each of 32 patients with PEX and 32 age-matched non-PEX subjects was evaluated preoperatively and on the 1st, 7th, and 30th days after uncomplicated phacoemulsification surgery in this retrospective case-control study. Nuclear firmness, corneal edema (CE), anterior chamber reaction (ACR) intensity were graded by a slit-lamp microscope. Endothelial cell density (ECD), coefficient of variation in cell area (CV), hexagonal cell ratio (HEX), and central corneal thickness (CCT) were measured using a non-contact specular microscope. Results: There was no significant group-difference in age, sex, corneal edema (CE), anterior chamber reaction (ACR), coefficient of variation in cell area (CV), and hexagonal cell ratio (HEX). Mean effective phaco time (EPT) was significantly lower intraoperatively (pst (pth (p=0.011), and 30th (p=0.025) days postoperatively in the PEX group than in the non-PEX group. Mean ECD was significantly lower in the PEX group than in the non-PEX group on 7th (p=0.013), and 30th (p=0.037) days postoperatively. The mean CCT significantly differed only on the 1st (p<0.001) day postoperatively. Discussion and Conclusion: Eyes with PEX presented lower corneal ECD and decreased BCVA after uncomplicated phacoemulsification surgery. Further, there was no association between CCT and PEX existence preoperatively and in the early postoperative period.

CORNEA diseases; CORNEA; ANTERIOR chamber (Eye); DATA analysis; PHACOEMULSIFICATION; EXFOLIATION syndrome; SEX distribution; RETROSPECTIVE studies; AGE distribution; MANN Whitney U Test; CHI-squared test; DESCRIPTIVE statistics; ENDOTHELIAL cells; MEDICAL records; ACQUISITION of data; CASE-control method; STATISTICS; POSTOPERATIVE period; VISUAL acuity; CORNEA measurement; DATA analysis software; NONPARAMETRIC statistics

Haydarpaşa Numune Medical Journal, 2024, Vol 64, Issue 2, p234

2630-5720

Academic Journal

10.14744/hnhj.2022.93284